Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Aphasia, Broca D001039 1 associated lipids
T-Lymphocytopenia, Idiopathic CD4-Positive D018344 1 associated lipids
Ectodermal Dysplasia D004476 1 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Epiglottitis D004826 1 associated lipids
Tick Bites D064927 1 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Myelitis, Transverse D009188 1 associated lipids
Furcation Defects D017823 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Pseudolymphoma D019310 1 associated lipids
Achondroplasia D000130 1 associated lipids
Leishmaniasis, Mucocutaneous D007897 1 associated lipids
Trismus D014313 1 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Trichiasis D058457 1 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Paratyphoid Fever D010284 1 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Abdominal Abscess D018784 2 associated lipids
Typhoid Fever D014435 2 associated lipids
Furunculosis D005667 2 associated lipids
Tooth Erosion D014077 2 associated lipids
Heartburn D006356 2 associated lipids
Pyomyositis D052880 2 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Elephantiasis D004604 2 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Tooth Mobility D014086 2 associated lipids
Hoarseness D006685 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Toxoplasmosis, Congenital D014125 2 associated lipids
Bites, Human D001734 2 associated lipids
Penile Diseases D010409 2 associated lipids
Herpes Genitalis D006558 2 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Amebiasis D000562 2 associated lipids
Pericoronitis D010497 2 associated lipids
Lung Diseases, Parasitic D008174 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Sidhu H et al. Risk assessment of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30463165
Sidhu H et al. Plant toxicity and accumulation of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30340267
Sidhu H et al. Retention-release of ciprofloxacin and azithromycin in biosolids and biosolids-amended soils. 2019 Sci. Total Environ. pmid:30196217
Sidhu H et al. Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: Microbial toxicity and earthworm responses. 2019 Sci. Total Environ. pmid:30195128
Revello R et al. Prediction of chorioamnionitis in cases of intraamniotic infection by ureaplasma urealyticum in women with very preterm premature rupture of membranes or preterm labour. 2018 J. Matern. Fetal. Neonatal. Med. pmid:28502201
Sanchez Garcia D et al. Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) - A comparison with lysosomotropic drugs. 2018 Chem. Biol. Interact. pmid:29248446
Obaro S Azithromycin and Childhood Mortality in Africa. 2018 N. Engl. J. Med. pmid:30284804
Michelow IC and Sánchez PJ Azithromycin and Childhood Mortality in Africa. 2018 N. Engl. J. Med. pmid:30284803
Wei W et al. MPEG-PCL Copolymeric Micelles for Encapsulation of Azithromycin. 2018 AAPS PharmSciTech pmid:29675667
Barge L et al. Transient immune-mediated agranulocytosis following infection. 2018 BMJ Case Rep pmid:29669774