Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vallejo C et al. | Resolution of cyclosporine-induced gingival hyperplasia resistant to azithromycin by switching to tacrolimus. | 2001 | Haematologica | pmid:11146586 |
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| Miyazaki S et al. | Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice. | 2001 | J. Antimicrob. Chemother. | pmid:11533011 |
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| Jacks S et al. | Pharmacokinetics of azithromycin and concentration in body fluids and bronchoalveolar cells in foals. | 2001 | Am. J. Vet. Res. | pmid:11763173 |
| Kays MB and Denys GA | In vitro activity and pharmacodynamics of azithromycin and clarithromycin against Streptococcus pneumoniae based on serum and intrapulmonary pharmacokinetics. | 2001 | Clin Ther | pmid:11318076 |
| Dinos GP et al. | Insights into the mechanism of azithromycin interaction with an Escherichia coli functional ribosomal complex. | 2001 | Mol. Pharmacol. | pmid:11353804 |
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| Parsad D et al. | Azithromycin monthly pulse vs daily doxycycline in the treatment of acne vulgaris. | 2001 | J. Dermatol. | pmid:11280457 |
| Waring AL et al. | Development of a genomics-based PCR assay for detection of Mycoplasma pneumoniae in a large outbreak in New York State. | 2001 | J. Clin. Microbiol. | pmid:11283060 |
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| Di Paolo A et al. | Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily. | 2002 | Pharmacol. Res. | pmid:12457629 |
| Chiu LM et al. | Pharmacokinetics of intravenous azithromycin and ceftriaxone when administered alone and concurrently to healthy volunteers. | 2002 | J. Antimicrob. Chemother. | pmid:12461037 |
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| Kamau FN et al. | Isocratic liquid chromatographic method for the analysis of azithromycin and its structurally related substances in bulk samples. | 2002 | J Chromatogr Sci | pmid:12433117 |
| Tyteca D et al. | Azithromycin, a lysosomotropic antibiotic, has distinct effects on fluid-phase and receptor-mediated endocytosis, but does not impair phagocytosis in J774 macrophages. | 2002 | Exp. Cell Res. | pmid:12441132 |
| Aguirrebengoa K et al. | [Endocarditis due to Bartonella henselae on a native valve. A new case with some notable aspects]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:12372243 |
| Blondeau JM | The evolution and role of macrolides in infectious diseases. | 2002 | Expert Opin Pharmacother | pmid:12150692 |
| Khan WA et al. | Comparison of single-dose azithromycin and 12-dose, 3-day erythromycin for childhood cholera: a randomised, double-blind trial. | 2002 | Lancet | pmid:12480424 |
| Weiss LM | Babesiosis in humans: a treatment review. | 2002 | Expert Opin Pharmacother | pmid:12150690 |
| Rao RU et al. | Brugia malayi: effects of antibacterial agents on larval viability and development in vitro. | 2002 | Exp. Parasitol. | pmid:12243742 |
| Pastor E et al. | [Macrolide consumption according to geographic areas in the province of Valladolid]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:12433351 |
| Matute AJ et al. | Double-blind, placebo-controlled study comparing the effect of azithromycin with clarithromycin on oropharyngeal and bowel microflora in volunteers. | 2002 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:12111597 |
| Williams ES and Miller JM | Results from late-breaking clinical trial sessions at the American College of Cardiology 51st Annual Scientific Session. | 2002 | J. Am. Coll. Cardiol. | pmid:12113263 |
| Kopjar B | Azithromycin is effective in patients with chronic bronchitis. | 2002 | J. Antimicrob. Chemother. | pmid:12205072 |
| Baschiera F et al. | Improved tonsillar disposition of azithromycin following a 3-day oral treatment with 20 mg kg(-1) in paediatric patients. | 2002 | Pharmacol. Res. | pmid:12208127 |
| Maizumi N et al. | Quantitative comparison of the cytocidal effect of seven macrolide antibiotics on human periodontal ligament fibroblasts. | 2002 | J. Periodont. Res. | pmid:12200967 |
| House D et al. | Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever. | 2002 | J. Infect. Dis. | pmid:12134261 |
| Paladino JA et al. | Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia. | 2002 | Chest | pmid:12377852 |
| Wallace Jr RJ et al. | Repeat positive cultures in Mycobacterium intracellulare lung disease after macrolide therapy represent new infections in patients with nodular bronchiectasis. | 2002 | J. Infect. Dis. | pmid:12134265 |
| Cheng H et al. | Synthesis and SAR of azalide 3,6-ketal aromatic derivatives as potent Gram-positive and Gram-negative antibacterial agents. | 2002 | Bioorg. Med. Chem. Lett. | pmid:12161150 |
| Kawashima M et al. | Inhibitory effects of 14-membered ring macrolide antibiotics on bleomycin-induced acute lung injury. | 2002 | Lung | pmid:12182159 |
| Yee CL et al. | Tendon or joint disorders in children after treatment with fluoroquinolones or azithromycin. | 2002 | Pediatr. Infect. Dis. J. | pmid:12182376 |
| Clark C et al. | In vitro selection of resistance in Haemophilus influenzae by amoxicillin-clavulanate, cefpodoxime, cefprozil, azithromycin, and clarithromycin. | 2002 | Antimicrob. Agents Chemother. | pmid:12183253 |
| Blandizzi C et al. | Distribution of azithromycin in plasma and tonsil tissue after repeated oral administration of 10 or 20 milligrams per kilogram in pediatric patients. | 2002 | Antimicrob. Agents Chemother. | pmid:11959610 |
| Ekici A et al. | Effect of azithromycin on the severity of bronchial hyperresponsiveness in patients with mild asthma. | 2002 | J Asthma | pmid:11990233 |
| Mohler AM | Treatment of streptococcal pharyngitis. | 2002 | Am Fam Physician | pmid:11996411 |
| Cohen R et al. | Comparison of two dosages of azithromycin for three days versus penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. | 2002 | Pediatr. Infect. Dis. J. | pmid:12075760 |
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| Babl FE et al. | Experimental acute otitis media due to nontypeable Haemophilus influenzae: comparison of high and low azithromycin doses with placebo. | 2002 | Antimicrob. Agents Chemother. | pmid:12069974 |
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| Kays MB et al. | Azithromycin treatment failure in community-acquired pneumonia caused by Streptococcus pneumoniae resistant to macrolides by a 23S rRNA mutation. | 2002 | Diagn. Microbiol. Infect. Dis. | pmid:12088625 |
| Breier AR et al. | Microbiological assay for azithromycin in pharmaceutical formulations. | 2002 | J Pharm Biomed Anal | pmid:12093530 |
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| Sirois F | [Delirium associated with azithromycin administration]. | 2002 | Can J Psychiatry | pmid:12211892 |
| Fraser-Hurt N and Mabey D | Trachoma. | 2002 | Clin Evid | pmid:12230687 |
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| Chandrupatla S et al. | Azithromycin-induced intrahepatic cholestasis. | 2002 | Dig. Dis. Sci. | pmid:12395890 |
| Steinberg JM and Srugo I | Reoccurrence of culture-positive pertussis in an infant initially treated with azithromycin and steroids. | 2002 | Arch Pediatr Adolesc Med | pmid:12361458 |
| Hauben M and Amsden GW | The association of erythromycin and infantile hypertrophic pyloric stenosis: causal or coincidental? | 2002 | Drug Saf | pmid:12381214 |
| Duff P | Antibiotic selection in obstetrics: making cost-effective choices. | 2002 | Clin Obstet Gynecol | pmid:11862059 |
| Wolter J et al. | Effect of long term treatment with azithromycin on disease parameters in cystic fibrosis: a randomised trial. | 2002 | Thorax | pmid:11867823 |
| Zhou F et al. | High accuracy mass measurement of peptides with internal calibration using a dual electrospray ionization sprayer system for protein identification. | 2002 | Rapid Commun. Mass Spectrom. | pmid:11870887 |
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| Cascio A et al. | Clarithromycin versus azithromycin in the treatment of Mediterranean spotted fever in children: a randomized controlled trial. | 2002 | Clin. Infect. Dis. | pmid:11740701 |
| Schachter J and Dawson CR | Elimination of blinding trachoma. | 2002 | Curr. Opin. Infect. Dis. | pmid:12686881 |
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| Kutlin A et al. | Effect of prolonged treatment with azithromycin, clarithromycin, or levofloxacin on Chlamydia pneumoniae in a continuous-infection Model. | 2002 | Antimicrob. Agents Chemother. | pmid:11796350 |
| Strle F and Maraspin V | Is azithromycin treatment associated with prolongation of the Q-Tc interval? | 2002 | Wien. Klin. Wochenschr. | pmid:12708094 |
| Dawson CR and Schachter J | Should trachoma be treated with antibiotics? | 2002 | Lancet | pmid:11812548 |
| Dai G et al. | [Researching some sensitivity factor of bioassay method on the antibiotics pharmacokinetics]. | 2002 | Hunan Yi Ke Da Xue Xue Bao | pmid:12575254 |
| Dzelalija B et al. | Randomized trial of azithromycin in the prophylaxis of Mediterranean spotted fever. | 2002 | Acta Med Croatica | pmid:12596623 |
| Nalbanski B and Nalbanski A | [Treatment of Chlamydia trachomatis with azatril]. | 2002 | Akush Ginekol (Sofiia) | pmid:11935692 |
| Krumov G et al. | [Treatment of chlamydial cervicitis with azatril]. | 2002 | Akush Ginekol (Sofiia) | pmid:11935693 |