Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

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Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Male Urogenital Diseases D052801 1 associated lipids
Trichiasis D058457 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Paratyphoid Fever D010284 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
T-Lymphocytopenia, Idiopathic CD4-Positive D018344 1 associated lipids
Ectodermal Dysplasia D004476 1 associated lipids
Aphasia, Broca D001039 1 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Myelitis, Transverse D009188 1 associated lipids
Epiglottitis D004826 1 associated lipids
Tick Bites D064927 1 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Furcation Defects D017823 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Achondroplasia D000130 1 associated lipids
Pseudolymphoma D019310 1 associated lipids
Leishmaniasis, Mucocutaneous D007897 1 associated lipids
Trismus D014313 1 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Lung Diseases, Parasitic D008174 2 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Tuberculosis, Urogenital D014401 2 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Toxoplasmosis, Ocular D014126 2 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Typhoid Fever D014435 2 associated lipids
Furunculosis D005667 2 associated lipids
Abdominal Abscess D018784 2 associated lipids
Pyomyositis D052880 2 associated lipids
Tooth Erosion D014077 2 associated lipids
Heartburn D006356 2 associated lipids
Elephantiasis D004604 2 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Tooth Mobility D014086 2 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Toxoplasmosis, Congenital D014125 2 associated lipids
Hoarseness D006685 2 associated lipids
Penile Diseases D010409 2 associated lipids
Bites, Human D001734 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Slavinsky J et al. Factors associated with the decline in sexually transmitted infections among HIV-positive women. 2000 J. Acquir. Immune Defic. Syndr. pmid:10708065
Angelilli ML et al. Palatability of oral antibiotics among children in an urban primary care center. 2000 Arch Pediatr Adolesc Med pmid:10710025
Rino BE et al. Azithromycin in the treatment of plasmodium falciparum gametocytes: a preliminary observation. 2000 J. Trop. Pediatr. pmid:10730047
Canut Blasco A et al. [A randomized, prospective and comparative study is a clinical trial]. 2000 Med Clin (Barc) pmid:10734631
Potts JM et al. Association of chronic urinary symptoms in women and Ureaplasma urealyticum. 2000 Urology pmid:10736488
Ouchi K Chlamydia pneumoniae and atherosclerosis. 1999 Jpn. J. Infect. Dis. pmid:10738358
Schissel DJ et al. Azithromycin eruption in infectious mononucleosis: a proposed mechanism of interaction. 2000 Cutis pmid:10738636
Giacometti A et al. Activity of nitazoxanide alone and in combination with azithromycin and rifabutin against Cryptosporidium parvum in cell culture. 2000 J. Antimicrob. Chemother. pmid:10747821
Nishi Y et al. [Effect of macrolide antibiotics on adhesion by cancer cells]. 2000 Jpn J Antibiot pmid:10756450
Wenisch C [Pharmacokinetic effects of antibiotics on the development of bacterial resistance particularly in reference to azithromycin]. 2000 Wien Med Wochenschr pmid:10756595
Diculencu D et al. [The postantibiotic effect of azithromycin on respiratory pathogens]. 1998 Jul-Dec Rev Med Chir Soc Med Nat Iasi pmid:10756861
Somani J et al. Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure. 2000 J. Infect. Dis. pmid:10762573
El-Sadr WM et al. Discontinuation of prophylaxis for Mycobacterium avium complex disease in HIV-infected patients who have a response to antiretroviral therapy. Terry Beirn Community Programs for Clinical Research on AIDS. 2000 N. Engl. J. Med. pmid:10766581
Brieland JK et al. Efficacy of SCH27899 in an animal model of Legionnaires' disease using immunocompromised A/J mice. 2000 Antimicrob. Agents Chemother. pmid:10770771
Najib MM et al. Cost-effectiveness of sparfloxacin compared with other oral antimicrobials in outpatient treatment of community-acquired pneumonia. 2000 Pharmacotherapy pmid:10772376
Laming AC et al. A targeted, single-dose azithromycin strategy for trachoma. 2000 Med. J. Aust. pmid:10772587
Donders GG Treatment of sexually transmitted bacterial diseases in pregnant women. 2000 Drugs pmid:10776830
Bujanda L et al. Ranitidine bismuth citrate plus azithromycin for Helicobacter pylori eradication. 2000 J. Clin. Gastroenterol. pmid:10777206
Ress BD and Gross EM Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. 2000 Ann. Otol. Rhinol. Laryngol. pmid:10778901
Miller SA et al. Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human vascular smooth muscle and induces cellular proliferation. 2000 J. Surg. Res. pmid:10781378