Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bala M et al. | Trends of resistance to antimicrobials recommended currently and in the past for management of gonorrhea in the Apex STD center in India and comparison of antimicrobial resistance profile between 2002-2006 and 2007-2012. | 2015 | Sex Transm Dis | pmid:25763675 |
| Bianchi A et al. | Kinetics of Chlamydia trachomatis clearance in patients with azithromycin, as assessed by first void urine testing by PCR and transcription-mediated amplification. | 1998 | Sex Transm Dis | pmid:9713917 |
| Schillinger JA et al. | Patient-delivered partner treatment with azithromycin to prevent repeated Chlamydia trachomatis infection among women: a randomized, controlled trial. | 2003 | Sex Transm Dis | pmid:12514443 |
| Martin DH | The US Chlamydia trachomatis control program: successes, shortcomings and ideas for the future. | 2012 | Sex Transm Dis | pmid:23169170 |
| Kerani RP et al. | Gonorrhea treatment practices in the STD Surveillance Network, 2010-2012. | 2015 | Sex Transm Dis | pmid:25504294 |
| Chen XS | Azithromycin versus penicillin G benzathine for early syphilis. | 2012 | Sex Transm Dis | pmid:23060081 |
| Soge OO et al. | Emergence of increased azithromycin resistance during unsuccessful treatment of Neisseria gonorrhoeae infection with azithromycin (Portland, OR, 2011). | 2012 | Sex Transm Dis | pmid:23064537 |
| Sosa J et al. | High percentages of resistance to tetracycline and penicillin and reduced susceptibility to azithromycin characterize the majority of strain types of Neisseria gonorrhoeae isolates in Cuba, 1995-1998. | 2003 | Sex Transm Dis | pmid:12916137 |
| Okah E et al. | Sentinel Surveillance for Expedited Partner Therapy Prescriptions Using Pharmacy Data, in 2 New York City Neighborhoods, 2015. | 2017 | Sex Transm Dis | pmid:28079746 |
| Hook EW et al. | A randomized, comparative pilot study of azithromycin versus benzathine penicillin G for treatment of early syphilis. | 2002 | Sex Transm Dis | pmid:12172535 |
| Sahin-Hodoglugil NN et al. | A comparison of cost-effectiveness of three protocols for diagnosis and treatment of gonococcal and chlamydial infections in women in Africa. | 2003 | Sex Transm Dis | pmid:12916139 |
| Beymer MR et al. | Evaluation of gonorrhea test of cure at 1 week in a Los Angeles community-based clinic serving men who have sex with men. | 2014 | Sex Transm Dis | pmid:25211254 |
| Beyda RM et al. | Azithromycin efficacy in the treatment of Chlamydia trachomatis among detained youth. | 2014 | Sex Transm Dis | pmid:25211253 |
| Tyndall MW et al. | Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. | 1994 Jul-Aug | Sex Transm Dis | pmid:7974076 |
| Katz KA et al. | Molecular epidemiology of syphilis--San Francisco, 2004-2007. | 2010 | Sex Transm Dis | pmid:20601928 |
| Zhu BY et al. | Surveillance of antimicrobial susceptibilities of Neisseria gonorrhoeae in Nanning, China, 2000 to 2012. | 2014 | Sex Transm Dis | pmid:25013979 |
| Labbé AC et al. | Periodical antibiotic treatment for the control of gonococcal and chlamydial infections among sex workers in Benin and Ghana: a cluster-randomized placebo-controlled trial. | 2012 | Sex Transm Dis | pmid:22421690 |
| Martin IE et al. | Molecular typing of Treponema pallidum strains in western Canada: predominance of 14d subtypes. | 2010 | Sex Transm Dis | pmid:20539263 |
| Lechtenberg RJ et al. | Variation in adherence to the treatment guidelines for Neisseria gonorrhoeae by clinical practice setting, California, 2009 to 2011. | 2014 | Sex Transm Dis | pmid:24722391 |
| Vandepitte J et al. | High prevalence of ciprofloxacin-resistant gonorrhea among female sex workers in Kampala, Uganda (2008-2009). | 2014 | Sex Transm Dis | pmid:24622633 |
| Campos-Outcalt D et al. | Use of directly observed azithromycin treatment for syphilis in a homeless woman. | 2002 | Sex Transm Dis | pmid:12035029 |
| Tapsall JW et al. | Failure of azithromycin therapy in gonorrhea and discorrelation with laboratory test parameters. | 1998 | Sex Transm Dis | pmid:9858344 |
| Chaudhary C et al. | A pilot study on antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Nepal. | 2005 | Sex Transm Dis | pmid:16205307 |
| Schumacher CM and Ghanem KG | Retreatment rates for uncomplicated gonorrhea infection: comparing ceftriaxone and azithromycin versus ceftriaxone and doxycycline. | 2013 | Sex Transm Dis | pmid:23965767 |
| Lázaro MJ et al. | A case of late-stage lymphogranuloma venereum in a woman in Europe. | 2013 | Sex Transm Dis | pmid:24275729 |
| Abdolrasouli A and Roushan A | Corynebacterium propinquum associated with acute, nongonococcal urethritis. | 2013 | Sex Transm Dis | pmid:24275738 |
| McLean CA et al. | The emergence of Neisseria gonorrhoeae with decreased susceptibility to Azithromycin in Kansas City, Missouri, 1999 to 2000. | 2004 | Sex Transm Dis | pmid:14743069 |
| Farley TA et al. | The acceptability and behavioral effects of antibiotic prophylaxis for syphilis prevention. | 2003 | Sex Transm Dis | pmid:14603093 |
| Rahangdale L et al. | An observational cohort study of Chlamydia trachomatis treatment in pregnancy. | 2006 | Sex Transm Dis | pmid:16432482 |
| O'Farrell N et al. | Periodic presumptive treatment for cervical infections in service women in 3 border provinces of Laos. | 2006 | Sex Transm Dis | pmid:16645552 |
| Levy V et al. | A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea. | 2016 | Sex Transm Dis | pmid:26967304 |
| Mmeje O and Coleman JS | Concurrent patient-partner treatment in pregnancy: an alternative to expedited partner therapy? | 2012 | Sex Transm Dis | pmid:22902661 |
| Blandford JM and Gift TL | The cost-effectiveness of single-dose azithromycin for treatment of incubating syphilis. | 2003 | Sex Transm Dis | pmid:12782951 |
| Dillon JA et al. | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from three Caribbean countries: Trinidad, Guyana, and St. Vincent. | 2001 | Sex Transm Dis | pmid:11518867 |
| Dillon JA et al. | Reduced susceptibility to azithromycin and high percentages of penicillin and tetracycline resistance in Neisseria gonorrhoeae isolates from Manaus, Brazil, 1998. | 2001 | Sex Transm Dis | pmid:11518869 |
| Meltzer MC et al. | Association of Mobiluncus curtisii with recurrence of bacterial vaginosis. | 2008 | Sex Transm Dis | pmid:18418301 |
| SteingrÃmsson O et al. | Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men. | 1994 Jan-Feb | Sex Transm Dis | pmid:8140488 |
| Barberá MJ et al. | Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance: Prevalence and Risk Factors Among a 2013-2014 Cohort of Patients in Barcelona, Spain. | 2017 | Sex Transm Dis | pmid:28703723 |
| Yuan LF et al. | Resistance to azithromycin of Neisseria gonorrhoeae isolates from 2 cities in China. | 2011 | Sex Transm Dis | pmid:21844727 |
| Dan M et al. | Pharyngeal Gonorrhea in female sex workers: Response to a single 2-g dose of azithromycin. | 2006 | Sex Transm Dis | pmid:16572040 |
| Kiddugavu MG et al. | Effectiveness of syphilis treatment using azithromycin and/or benzathine penicillin in Rakai, Uganda. | 2005 | Sex Transm Dis | pmid:15614114 |
| Hottes TS et al. | Cephalosporin and azithromycin susceptibility in Neisseria gonorrhoeae isolates by site of infection, British Columbia, 2006 to 2011. | 2013 | Sex Transm Dis | pmid:23250301 |
| Llata E et al. | Management of Pelvic Inflammatory Disease in Selected U.S. Sexually Transmitted Disease Clinics: Sexually Transmitted Disease Surveillance Network, January 2010-December 2011. | 2015 | Sex Transm Dis | pmid:26165434 |
| Tabidze IL et al. | Adherence to Centers for Disease Control and Prevention Gonococcal Treatment Guidelines Among Chicago Health Care Providers, 2011-2012. | 2015 | Sex Transm Dis | pmid:26165433 |
| Dombrowski JC and Batteiger BE | Reconsidering the Use of Azithromycin for Chlamydial Urethritis. | 2016 | Sex Transm Dis | pmid:27626187 |
| Handsfield HH | Questioning azithromycin for chlamydial infection. | 2011 | Sex Transm Dis | pmid:21992978 |
| Lau CY and Qureshi AK | Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. | 2002 | Sex Transm Dis | pmid:12218839 |
| Herchline TE and Inkrott BP | Resistance trends in Neisseria gonorrhoeae in southwestern Ohio. | 2010 | Sex Transm Dis | pmid:19901861 |
| Gose SO et al. | Failure of azithromycin 2.0 g in the treatment of gonococcal urethritis caused by high-level resistance in California. | 2015 | Sex Transm Dis | pmid:25868141 |
| Van Damme K et al. | Evaluation of azithromycin resistance in Treponema pallidum specimens from Madagascar. | 2009 | Sex Transm Dis | pmid:19901863 |