Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Achondroplasia D000130 1 associated lipids
Acinetobacter Infections D000151 4 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
Amebiasis D000562 2 associated lipids
Anaphylaxis D000707 35 associated lipids
Anaplasmataceae Infections D000711 3 associated lipids
Angina, Unstable D000789 14 associated lipids
Aphasia, Broca D001039 1 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Bacterial Infections D001424 21 associated lipids
Bartonella Infections D001474 3 associated lipids
Birth Weight D001724 23 associated lipids
Bites, Human D001734 2 associated lipids
Blister D001768 16 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Burns D002056 34 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cat Diseases D002371 12 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Uterine Cervicitis D002575 3 associated lipids
Chancroid D002602 4 associated lipids
Chlamydia Infections D002690 7 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Chronic Disease D002908 7 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Colitis D003092 69 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Corneal Opacity D003318 3 associated lipids
Coronary Disease D003327 70 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Crohn Disease D003424 12 associated lipids
Cross Infection D003428 9 associated lipids
Cryptosporidiosis D003457 3 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Stout JE and Floto RA Treatment of Mycobacterium abscessus: all macrolides are equal, but perhaps some are more equal than others. 2012 Am. J. Respir. Crit. Care Med. pmid:23118083
Hayes D et al. ABCA3 transporter deficiency. 2012 Am. J. Respir. Crit. Care Med. pmid:23071193
Verleden GM et al. Azithromycin reduces airway neutrophilia and interleukin-8 in patients with bronchiolitis obliterans syndrome. 2006 Am. J. Respir. Crit. Care Med. pmid:16741151
Williams TJ and Verleden GM Azithromycin: a plea for multicenter randomized studies in lung transplantation. 2005 Am. J. Respir. Crit. Care Med. pmid:16148194
Saiman L et al. Heterogeneity of treatment response to azithromycin in patients with cystic fibrosis. 2005 Am. J. Respir. Crit. Care Med. pmid:16040785
Kunisaki KM et al. Vitamin D levels and risk of acute exacerbations of chronic obstructive pulmonary disease: a prospective cohort study. 2012 Am. J. Respir. Crit. Care Med. pmid:22077070
Restrepo MI and Anzueto A Macrolide antibiotics for prevention of chronic obstructive pulmonary disease exacerbations: are we there yet? 2014 Am. J. Respir. Crit. Care Med. pmid:24983214
Lococo F et al. Hemoptysis and Progressive Dyspnea in a 67-Year-Old Woman with History of Renal Transplantation. 2016 Am. J. Respir. Crit. Care Med. pmid:26681504
Yates B et al. Azithromycin reverses airflow obstruction in established bronchiolitis obliterans syndrome. 2005 Am. J. Respir. Crit. Care Med. pmid:15976371
Hodge S et al. Azithromycin improves macrophage phagocytic function and expression of mannose receptor in chronic obstructive pulmonary disease. 2008 Am. J. Respir. Crit. Care Med. pmid:18420960
Gerhardt SG et al. Maintenance azithromycin therapy for bronchiolitis obliterans syndrome: results of a pilot study. 2003 Am. J. Respir. Crit. Care Med. pmid:12672648
Albert RK and Schuller JL Macrolide antibiotics and the risk of cardiac arrhythmias. 2014 Am. J. Respir. Crit. Care Med. pmid:24707986
Han MK et al. Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy. 2014 Am. J. Respir. Crit. Care Med. pmid:24779680
Mertens V et al. Bile acids aspiration reduces survival in lung transplant recipients with BOS despite azithromycin. 2011 Am. J. Transplant. pmid:21272237
Glanville AR CLAD: does the Emperor have new clothes? 2014 Am. J. Transplant. pmid:25394597
Verleden SE et al. Lymphocytic bronchiolitis after lung transplantation is associated with daily changes in air pollution. 2012 Am. J. Transplant. pmid:22682332
Vanaudenaerde BM et al. Macrolides inhibit IL17-induced IL8 and 8-isoprostane release from human airway smooth muscle cells. 2007 Am. J. Transplant. pmid:17061983
Greer M et al. Phenotyping established chronic lung allograft dysfunction predicts extracorporeal photopheresis response in lung transplant patients. 2013 Am. J. Transplant. pmid:23406373
Robertson AG et al. Targeting allograft injury and inflammation in the management of post-lung transplant bronchiolitis obliterans syndrome. 2009 Am. J. Transplant. pmid:19459806
Ruttens D et al. Prophylactic Azithromycin Therapy After Lung Transplantation: Post hoc Analysis of a Randomized Controlled Trial. 2016 Am. J. Transplant. pmid:26372728