Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Aguirrebengoa K et al. | [Endocarditis due to Bartonella henselae on a native valve. A new case with some notable aspects]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:12372243 |
Paladino JA et al. | Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia. | 2002 | Chest | pmid:12377852 |
Ivashkin VT et al. | Azithromycin in a triple therapy for H.pylori eradication in active duodenal ulcer. | 2002 | World J. Gastroenterol. | pmid:12378634 |
Hauben M and Amsden GW | The association of erythromycin and infantile hypertrophic pyloric stenosis: causal or coincidental? | 2002 | Drug Saf | pmid:12381214 |
Itoh M et al. | [A case of immotile-dyskinetic cilia syndrome responding to clenbuterol hydrochloride and azithromycin]. | 2002 | Nihon Kokyuki Gakkai Zasshi | pmid:12382429 |
Equi A et al. | Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial. | 2002 | Lancet | pmid:12383667 |
Ohara T et al. | Effects of azithromycin on shiga toxin production by Escherichia coli and subsequent host inflammatory response. | 2002 | Antimicrob. Agents Chemother. | pmid:12384353 |
Sullivan B et al. | Comparison of azithromycin and clarithromycin in triple therapy regimens for the eradication of Helicobacter pylori. | 2002 | Am. J. Gastroenterol. | pmid:12385435 |
Brook I | Antibacterial therapy for acute group a streptococcal pharyngotonsillitis: short-course versus traditional 10-day oral regimens. | 2002 | Paediatr Drugs | pmid:12390046 |
Chandrupatla S et al. | Azithromycin-induced intrahepatic cholestasis. | 2002 | Dig. Dis. Sci. | pmid:12395890 |
Mileusnic D et al. | Pathological case of the month: sudden death in a child as a result of pancreatitis during valproic acid therapy. | 2002 Sep-Oct | Pediatr Pathol Mol Med | pmid:12396903 |
Shor A | Atherosclerosis: lipid infiltration or Chlamydia pneumoniae infection? | 2002 | Circulation | pmid:12403680 |
Orfila J et al. | [Systematic screening for Chlamydia trachomatis with the molecular biological AMP-CT test in urine samples from young women]. | 2002 | J Gynecol Obstet Biol Reprod (Paris) | pmid:12407326 |
Krolewiecki A et al. | Activity of azithromycin against Leishmania major in vitro and in vivo. | 2002 | Am. J. Trop. Med. Hyg. | pmid:12408666 |
Neumann FJ | Chlamydia pneumoniae-atherosclerosis link: a sound concept in search for clinical relevance. | 2002 | Circulation | pmid:12417534 |
Woolard S and Kenkel D | Heading off antibiotic resistance. | 2001 | Adv Nurse Pract | pmid:12420432 |
Skerk V et al. | Comparative analysis of azithromycin and clarithromycin efficacy and tolerability in the treatment of chronic prostatitis caused by Chlamydia trachomatis. | 2002 | J Chemother | pmid:12420857 |
Tambiah J and Powell JT | Chlamydia pneumoniae antigens facilitate experimental aortic dilatation: prevention with azithromycin. | 2002 | J. Vasc. Surg. | pmid:12422113 |
Arnez M et al. | Solitary erythema migrans in children: comparison of treatment with azithromycin and phenoxymethylpenicillin. | 2002 | Wien. Klin. Wochenschr. | pmid:12422590 |
Maraspin V et al. | Development of erythema migrans in spite of treatment with antibiotics after a tick bite. | 2002 | Wien. Klin. Wochenschr. | pmid:12422612 |
Hall IH et al. | Disposition and intracellular activity of azithromycin in human THP-1 acute monocytes. | 2002 | Int. J. Antimicrob. Agents | pmid:12431870 |
Kadappu KK et al. | Azithromycin as treatment for cryptosporidiosis in human immunodeficiency virus disease. | 2002 Jul-Sep | J Postgrad Med | pmid:12432190 |
Kamau FN et al. | Isocratic liquid chromatographic method for the analysis of azithromycin and its structurally related substances in bulk samples. | 2002 | J Chromatogr Sci | pmid:12433117 |
Pastor E et al. | [Macrolide consumption according to geographic areas in the province of Valladolid]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:12433351 |
Tyteca D et al. | Azithromycin, a lysosomotropic antibiotic, has distinct effects on fluid-phase and receptor-mediated endocytosis, but does not impair phagocytosis in J774 macrophages. | 2002 | Exp. Cell Res. | pmid:12441132 |
Di Paolo A et al. | Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily. | 2002 | Pharmacol. Res. | pmid:12457629 |
Chiu LM et al. | Pharmacokinetics of intravenous azithromycin and ceftriaxone when administered alone and concurrently to healthy volunteers. | 2002 | J. Antimicrob. Chemother. | pmid:12461037 |
Ranque S et al. | Triangular test applied to the clinical trial of azithromycin against relapses in Plasmodium vivax infections. | 2002 | Malar. J. | pmid:12473182 |
Hauke W et al. | Esberitox N as supportive therapy when providing standard antibiotic treatment in subjects with a severe bacterial infection (acute exacerbation of chronic bronchitis). A multicentric, prospective, double-blind, placebo-controlled study. | 2002 | Chemotherapy | pmid:12476043 |
Khan WA et al. | Comparison of single-dose azithromycin and 12-dose, 3-day erythromycin for childhood cholera: a randomised, double-blind trial. | 2002 | Lancet | pmid:12480424 |
Williams K | Patient-delivered therapy: an additional means for addressing the Chlamydia trachomatis problem. | 2002 | Tenn Med | pmid:12491815 |
Arreaza L et al. | Emergence of gonococcal strains with resistance to azithromycin in Spain. | 2003 | J. Antimicrob. Chemother. | pmid:12493814 |
Allam AF and Shehab AY | Efficacy of azithromycin, praziquantel and mirazid in treatment of cryptosporidiosis in school children. | 2002 | J Egypt Soc Parasitol | pmid:12512828 |
Schillinger JA et al. | Patient-delivered partner treatment with azithromycin to prevent repeated Chlamydia trachomatis infection among women: a randomized, controlled trial. | 2003 | Sex Transm Dis | pmid:12514443 |
Bogomil'skiÄ MP and Komarov RM | [Azithromycin in the treatment of acute otitis media]. | 2002 | Antibiot. Khimioter. | pmid:12515096 |
Hand WI and Hand DL | [Mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes]. | 2002 | Antibiot. Khimioter. | pmid:12516190 |
Kogan R et al. | Comparative randomized trial of azithromycin versus erythromycin and amoxicillin for treatment of community-acquired pneumonia in children. | 2003 | Pediatr. Pulmonol. | pmid:12526069 |
Schultz KD and Oermann CM | Treatment of cast bronchitis with low-dose oral azithromycin. | 2003 | Pediatr. Pulmonol. | pmid:12526076 |
Ewald DP et al. | An evaluation of a SAFE-style trachoma control program in Central Australia. | 2003 | Med. J. Aust. | pmid:12526724 |
Ovetchkine P and Cohen R | Shortened course of antibacterial therapy for acute otitis media. | 2003 | Paediatr Drugs | pmid:12529165 |
[Antibiotics in routine practice. With proper selection rapid success]. | 2002 | MMW Fortschr Med | pmid:12532526 | |
[Azithromycin for pediatric indications. Brief therapy is ideal for children]. | 2002 | MMW Fortschr Med | pmid:12532527 | |
Goswick SM and Brenner GM | Activities of azithromycin and amphotericin B against Naegleria fowleri in vitro and in a mouse model of primary amebic meningoencephalitis. | 2003 | Antimicrob. Agents Chemother. | pmid:12543653 |
Hoffman HL et al. | Influence of macrolide susceptibility on efficacies of clarithromycin and azithromycin against Streptococcus pneumoniae in a murine lung infection model. | 2003 | Antimicrob. Agents Chemother. | pmid:12543686 |
Javaloy J et al. | Follicular conjunctivitis caused by Chlamydia trachomatis in an infant Saharan population: molecular and clinical diagnosis. | 2003 | Br J Ophthalmol | pmid:12543737 |
Gaynor BD et al. | Community treatment with azithromycin for trachoma is not associated with antibiotic resistance in Streptococcus pneumoniae at 1 year. | 2003 | Br J Ophthalmol | pmid:12543738 |
Niv Y and Abuksis G | Survey of the opinions, knowledge and practices of surgeons and internists regarding Helicobacter pylori test-and-treat policy. | 2003 | J. Clin. Gastroenterol. | pmid:12544197 |
Knuf M et al. | [Lymphadenitis colli due to non-tuberculous mycobacteria (NTM): a case-series and review of the literature]. | 2003 Jan-Feb | Klin Padiatr | pmid:12545419 |
Sanchez JL et al. | An outbreak of pneumococcal pneumonia among military personnel at high risk: control by low-dose azithromycin postexposure chemoprophylaxis. | 2003 | Mil Med | pmid:12546236 |
Rekart ML et al. | Targeted mass treatment for syphilis with oral azithromycin. | 2003 | Lancet | pmid:12559870 |