Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Miyagawa T et al. | Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-α. | 2016 | Arch. Oral Biol. | pmid:26655749 |
| Pawlowski KS et al. | Ototoxicity of topical azithromycin solutions in the guinea pig. | 2010 | Arch. Otolaryngol. Head Neck Surg. | pmid:20479380 |
| Brook I and Hausfeld JN | Effect of telithromycin and azithromycin on nasopharyngeal bacterial flora in patients with acute maxillary sinusitis. | 2006 | Arch. Otolaryngol. Head Neck Surg. | pmid:16618915 |
| Chan KH et al. | Efficacy of a new macrolide (azithromycin). For acute otitis media in the chinchilla model. | 1988 | Arch. Otolaryngol. Head Neck Surg. | pmid:2844210 |
| Wu ML et al. | Enterocolonic Mycobacterium avium-intracellulare. | 2002 | Arch. Pathol. Lab. Med. | pmid:11860323 |
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| Frota LC et al. | Helicobacter pylori eradication using tetracycline and furazolidone versus amoxicillin and azithromycin in lansoprazole based triple therapy: an open randomized clinical trial. | 2005 Apr-Jun | Arq Gastroenterol | pmid:16127567 |
| Assmann G et al. | Efficacy of antibiotic therapy for SAPHO syndrome is lost after its discontinuation: an interventional study. | 2009 | Arthritis Res. Ther. | pmid:19772564 |
| St Clair EW et al. | The effects of intravenous doxycycline therapy for rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial. | 2001 | Arthritis Rheum. | pmid:11357896 |
| Carter JD et al. | Combination antibiotics as a treatment for chronic Chlamydia-induced reactive arthritis: a double-blind, placebo-controlled, prospective trial. | 2010 | Arthritis Rheum. | pmid:20155838 |
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| Sultana TA et al. | Comparative pharmacokinetic and relative bioavailability study of coated and uncoated azithromycin powder for suspension in healthy Bangladeshi male volunteers. | 2011 | Arzneimittelforschung | pmid:22164968 |
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| Setiawati E et al. | Bioequivalence study of two azithromycin formulations in healthy subjects. | 2009 | Arzneimittelforschung | pmid:19856795 |
| Afghani T et al. | Preventing Long-Term Ocular Complications of Trachoma With Topical Azithromycin: A 3-Year Follow-up Study. | 2017 Jan-Feb | Asia Pac J Ophthalmol (Phila) | pmid:28161923 |
| Magri V et al. | Fluoroquinolone-macrolide combination therapy for chronic bacterial prostatitis: retrospective analysis of pathogen eradication rates, inflammatory findings and sexual dysfunction. | 2011 | Asian J. Androl. | pmid:21765442 |
| Karanth SS et al. | A rare case of community acquired Burkholderia cepacia infection presenting as pyopneumothorax in an immunocompetent individual. | 2012 | Asian Pac J Trop Biomed | pmid:23569891 |
| Jirapongsananuruk O et al. | Recurrent Campylobacter lari bacteremia in X-linked agammaglobulinemia: a case report and review. | 2006 Jun-Sep | Asian Pac. J. Allergy Immunol. | pmid:17136884 |
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| Schriever C et al. | Red wine, resveratrol, Chlamydia pneumoniae and the French connection. | 2003 | Atherosclerosis | pmid:14644410 |
| Hotomi M et al. | Nontypeable Haemophilus influenzae isolated from intractable acute otitis media internalized into cultured human epithelial cells. | 2010 | Auris Nasus Larynx | pmid:19505782 |
| Shimizu T and Suzaki H | Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. | 2016 | Auris Nasus Larynx | pmid:26441370 |
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| Saleh A et al. | Comparison of adjunctive azithromycin and amoxicillin/metronidazole for patients with chronic periodontitis: preliminary randomized control trial. | 2016 | Aust Dent J | pmid:26836781 |
| Fujise O et al. | Regenerative effect of azithromycin on periodontitis with different levels of gingival inflammation: three case reports. | 2014 | Aust Dent J | pmid:24861402 |
| Pradeep AR et al. | Local drug delivery of 0.5% azithromycin in the treatment of chronic periodontitis among smokers. | 2013 | Aust Dent J | pmid:23441790 |
| Gomi K et al. | Full-mouth scaling and root planing combined with azithromycin to treat peri-implantitis. | 2015 | Aust Dent J | pmid:25439282 |
| Bowden FJ and Skov SJ | Treating donovanosis. | 1999 | Aust Fam Physician | pmid:10615749 |
| Heal C et al. | Genital Chlamydia trachomatis infection - a study of general practice management in northern Queensland. | 2012 | Aust Fam Physician | pmid:22762073 |
| Pereira A et al. | Acute onset of widespread pustular eruption. | 2015 | Aust Fam Physician | pmid:26209988 |
| Redmond AM et al. | Epidemic syphilis exhibits diverse manifestations. | 2007 | Aust Fam Physician | pmid:17885710 |
| SendaÄŸ F et al. | Single dose oral azithromycin versus seven day doxycycline in the treatment of non-gonococcal mucopurulent endocervicitis. | 2000 | Aust N Z J Obstet Gynaecol | pmid:10870778 |
| van der Griend B et al. | An uncommon cause of a destructive vulval lesion. | 2001 | Aust N Z J Obstet Gynaecol | pmid:11787928 |
| Tsubouchi K et al. | Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4. | 2017 | Autophagy | pmid:28613983 |
| Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
| Juricic D et al. | Vanishing bile duct syndrome associated with azithromycin in a 62-year-old man. | 2010 | Basic Clin. Pharmacol. Toxicol. | pmid:19906050 |
| Srivastava P et al. | Azithromycin treatment modulates cytokine production in Chlamydia trachomatis infected women. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19389045 |
| Mary N and Mahmood TA | Preventing infective complications relating to induced abortion. | 2010 | Best Pract Res Clin Obstet Gynaecol | pmid:20542471 |
| Legrand T et al. | An optimal LC-MS/MS method for determination of azithromycin in white blood cells: application to pediatric samples. | 2014 | Bioanalysis | pmid:25383741 |
| Cigana C et al. | Anti-inflammatory effects of azithromycin in cystic fibrosis airway epithelial cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:17045242 |
| Berquand A et al. | Real-time imaging of drug-membrane interactions by atomic force microscopy. | 2004 | Biochim. Biophys. Acta | pmid:15328052 |
| Fa N et al. | Decrease of elastic moduli of DOPC bilayers induced by a macrolide antibiotic, azithromycin. | 2007 | Biochim. Biophys. Acta | pmid:17537401 |
| Kitsiouli E et al. | Effect of azithromycin on the LPS-induced production and secretion of phospholipase A2 in lung cells. | 2015 | Biochim. Biophys. Acta | pmid:25791017 |
| Wu Y et al. | Studies on electrochemical oxidation of azithromycin and its interaction with bovine serum albumin. | 2004 | Bioelectrochemistry | pmid:15219252 |
| Saini H et al. | Antimicrobial and antifouling efficacy of urinary catheters impregnated with a combination of macrolide and fluoroquinolone antibiotics against Pseudomonas aeruginosa. | 2016 | Biofouling | pmid:26982572 |