Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pieh C et al. | [Cotton wool spots in a 16-year-old girl]. | 2005 | Ophthalmologe | pmid:15095109 |
| Guchev IA et al. | Two regimens of azithromycin prophylaxis against community-acquired respiratory and skin/soft-tissue infections among military trainees. | 2004 | Clin. Infect. Dis. | pmid:15095213 |
| Fernandez-Obregon A | Oral use of azithromycin for the treatment of acne rosacea. | 2004 | Arch Dermatol | pmid:15096385 |
| Kohlhoff SA et al. | In vitro activity of a novel diaminopyrimidine compound, iclaprim, against Chlamydia trachomatis and C. pneumoniae. | 2004 | Antimicrob. Agents Chemother. | pmid:15105151 |
| Sakran W et al. | Susceptibility of Streptococcus pyogenes to two macrolides in northern Israel. | 2004 | Int. J. Antimicrob. Agents | pmid:15120735 |
| Bakar O et al. | Therapeutic potential of azithromycin in rosacea. | 2004 | Int. J. Dermatol. | pmid:15125511 |
| Worm HC et al. | High prevalence of Chlamydia pneumoniae infection in cyclosporin A-induced post-transplant gingival overgrowth tissue and evidence for the possibility of persistent infection despite short-term treatment with azithromycin. | 2004 | Nephrol. Dial. Transplant. | pmid:15128877 |
| Gonzalez BE et al. | Azithromycin compared with beta-lactam antibiotic treatment failures in pneumococcal infections of children. | 2004 | Pediatr. Infect. Dis. J. | pmid:15131461 |
| Gribajcević M et al. | [Clinical effectiveness of omeprazole, azithromycin and amoxicillin in ulcer healing and eradication of Helicobacter pylori infection]. | 2003 | Med Arh | pmid:15137249 |
| Parry CM | The treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever in Viet Nam. | 2004 | Trans. R. Soc. Trop. Med. Hyg. | pmid:15138078 |
| Klass P | Index case. | 2004 | N. Engl. J. Med. | pmid:15141038 |
| Duran D et al. | Theoretical study of selective methylation in the synthesis of azithromycin. | 2004 | J. Comput. Aided Mol. Des. | pmid:15143799 |
| Wyrick PB and Knight ST | Pre-exposure of infected human endometrial epithelial cells to penicillin in vitro renders Chlamydia trachomatis refractory to azithromycin. | 2004 | J. Antimicrob. Chemother. | pmid:15163653 |
| Agmon I et al. | Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism. | 2004 | FEBS Lett. | pmid:15165888 |
| Verleden GM and Dupont LJ | Azithromycin therapy for patients with bronchiolitis obliterans syndrome after lung transplantation. | 2004 | Transplantation | pmid:15167610 |
| Davies G and Wilson R | Prophylactic antibiotic treatment of bronchiectasis with azithromycin. | 2004 | Thorax | pmid:15170047 |
| Kaul R et al. | Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial. | 2004 | JAMA | pmid:15173146 |
| Peeling RW and Mabey DC | Syphilis. | 2004 | Nat. Rev. Microbiol. | pmid:15181902 |
| Hammerschlag MR and Roblin PM | The in vitro activity of a new fluoroquinolone, ABT-492, against recent clinical isolates of Chlamydia pneumoniae. | 2004 | J. Antimicrob. Chemother. | pmid:15190026 |
| Hunfeld KP et al. | New real-time PCR-based method for in vitro susceptibility testing of Anaplasma phagocytophilum against antimicrobial agents. | 2004 | Int. J. Antimicrob. Agents | pmid:15194126 |
| le Normand Y et al. | [Software modeling for better understanding of pharmacokinetic-pharmacodynamic relationships: application to azithromycin in the treatment of streptococcal tonsillitis and in acute exacerbation fo chronic bronchitis]]. | 2004 Jan-Feb | Therapie | pmid:15199685 |
| Halpern MT and Cifaldi MA | Is azithromycin the first-choice macrolide for treatment of community-acquired pneumonia? | 2004 | Clin. Infect. Dis. | pmid:15206068 |
| Carr RR and Nahata MC | Azithromycin for improving pulmonary function in cystic fibrosis. | 2004 | Ann Pharmacother | pmid:15213312 |
| Michot JM et al. | Active efflux of ciprofloxacin from J774 macrophages through an MRP-like transporter. | 2004 | Antimicrob. Agents Chemother. | pmid:15215125 |
| Hoberman A and Paradise JL | Study design questions in treatment of children with acute otitis media. | 2004 | Antimicrob. Agents Chemother. | pmid:15215151 |
| Drago L et al. | Selection of resistance of telithromycin against Haemophilus influenzae, Moraxella catarrhalis and streptococci in comparison with macrolides. | 2004 | J. Antimicrob. Chemother. | pmid:15215227 |
| Hillis GS et al. | Effects of a brief course of azithromycin on soluble cell adhesion molecules and markers of inflammation in survivors of an acute coronary syndrome: A double-blind, randomized, placebo-controlled study. | 2004 | Am. Heart J. | pmid:15215794 |
| Wu Y et al. | Studies on electrochemical oxidation of azithromycin and its interaction with bovine serum albumin. | 2004 | Bioelectrochemistry | pmid:15219252 |
| Hahn DL and Plane MB | Feasibility of a practical clinical trial for asthma conducted in primary care. | 2004 May-Jun | J Am Board Fam Pract | pmid:15226283 |
| Langley JM et al. | Azithromycin is as effective as and better tolerated than erythromycin estolate for the treatment of pertussis. | 2004 | Pediatrics | pmid:15231980 |
| Clyti E et al. | [Short treatment of donovanosis with azithromycin]. | 2004 | Ann Dermatol Venereol | pmid:15235534 |
| Snider LA and Swedo SE | PANDAS: current status and directions for research. | 2004 | Mol. Psychiatry | pmid:15241433 |
| Jacobs MR et al. | Study design questions in treatment of children with acute otitis media. | 2004 | Antimicrob. Agents Chemother. | pmid:15241848 |
| Lukehart SA et al. | Macrolide resistance in Treponema pallidum in the United States and Ireland. | 2004 | N. Engl. J. Med. | pmid:15247355 |
| Antibiotics ineffective for prevention of recurrent MI. | 2004 | J Fam Pract | pmid:15251088 | |
| Mizunoe S et al. | Clarithromycin and azithromycin induce apoptosis of activated lymphocytes via down-regulation of Bcl-xL. | 2004 | Int. Immunopharmacol. | pmid:15251115 |
| Bouwman JJ et al. | Azithromycin inhibits interleukin-6 but not fibrinogen production in hepatocytes infected with cytomegalovirus and chlamydia pneumoniae. | 2004 | J. Lab. Clin. Med. | pmid:15252403 |
| Tindberg Y et al. | Helicobacter pylori eradication in children and adolescents by a once daily 6-day treatment with or without a proton pump inhibitor in a double-blind randomized trial. | 2004 | Aliment. Pharmacol. Ther. | pmid:15274666 |
| Sicuranza GB and Figueroa R | Pregnancy in a woman with unilateral lung agenesis. | 2004 | J. Matern. Fetal. Neonatal. Med. | pmid:15280115 |
| Scheinfeld NS et al. | Macrolides in dermatology. | 2004 | Dis Mon | pmid:15280867 |
| Silva-Vergara ML et al. | Azithromycin in the treatment of mucosal leishmaniasis. | 2004 May-Jun | Rev. Inst. Med. Trop. Sao Paulo | pmid:15286825 |
| Nariai A et al. | [Efficacy of azithromycin as the empiric therapy in children with community-acquired pneumonia who were isolated macrolide resistant Streptococcus pneumoniae from nasopharynx]. | 2004 | Kansenshogaku Zasshi | pmid:15287476 |
| Koeth LM et al. | Streptococcus pneumoniae in vitro development of resistance to amoxicillin/clavulanic acid, cefaclor, levofloxacin and azithromycin. | 2004 | Int. J. Antimicrob. Agents | pmid:15288313 |
| Rahav G et al. | Azithromycin versus comparative therapy for the treatment of community acquired pneumonia. | 2004 | Int. J. Antimicrob. Agents | pmid:15288319 |
| Skerk V et al. | Comparative randomized pilot study of azithromycin and doxycycline efficacy in the treatment of prostate infection caused by Chlamydia trachomatis. | 2004 | Int. J. Antimicrob. Agents | pmid:15288321 |
| Lever MS et al. | In vitro susceptibility of Coxiella burnetii to azithromycin, doxycycline, ciprofloxacin and a range of newer fluoroquinolones. | 2004 | Int. J. Antimicrob. Agents | pmid:15288324 |
| Gregory AR et al. | Ophthalmomyiasis caused by the sheep bot fly Oestrus ovis in northern Iraq. | 2004 | Optom Vis Sci | pmid:15300116 |
| Nielsen HU et al. | Nasopharyngeal pathogens in children with acute otitis media in a low-antibiotic use country. | 2004 | Int. J. Pediatr. Otorhinolaryngol. | pmid:15302145 |
| Shrader SP et al. | Azithromycin and warfarin interaction. | 2004 | Pharmacotherapy | pmid:15303459 |
| Scheinfeld N | Telithromycin: a brief review of a new ketolide antibiotic. | 2004 Jul-Aug | J Drugs Dermatol | pmid:15303785 |