Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
| Liao YS et al. | Azithromycin-Nonsusceptible Shigella flexneri 3a in Men Who Have Sex with Men, Taiwan, 2015-2016. | 2016 | Emerging Infect. Dis. | pmid:28098533 |
| Gawin A et al. | Mildly pruritic palmar rash. | 2016 | J Fam Pract | pmid:28087868 |
| Paul SP et al. | Spontaneous surgical emphysema: an unusual complication of paediatric asthma. | 2016 | Br J Hosp Med (Lond) | pmid:27828753 |
| Espadas D et al. | Lack of effect of azithromycin on QT interval in children: a cohort study. | 2016 | Arch. Dis. Child. | pmid:27515186 |
| Serdar Kutuk M et al. | Relationship between maternal c-reactive protein level and neonatal outcome in patients with preterm premature rupture of membranes treated with Ampicillin and Azithromycin. | 2016 | J Obstet Gynaecol | pmid:27825282 |
| Ervin AM et al. | Surveillance and Azithromycin Treatment for Newcomers and Travelers Evaluation (ASANTE) Trial: Design and Baseline Characteristics. | 2016 | Ophthalmic Epidemiol | pmid:27820670 |
| Weintraub A et al. | In-vitro activity of solithromycin against anaerobic bacteria from the normal intestinal microbiota. | 2016 | Anaerobe | pmid:27725229 |
| Zhou Y et al. | Azithromycin therapy during respiratory syncytial virus bronchiolitis: Upper airway microbiome alterations and subsequent recurrent wheeze. | 2016 | J. Allergy Clin. Immunol. | pmid:27339392 |
| Berkowitz ST et al. | Resolution of spontaneous hemoabdomen secondary to peliosis hepatis following surgery and azithromycin treatment in a Bartonella species infected dog. | 2016 | J Vet Emerg Crit Care (San Antonio) | pmid:27074964 |
| MartÃn JM et al. | Azithromycin for the Treatment of Ciclosporin-Induced Gingival Hyperplasia. | 2016 | Actas Dermosifiliogr | pmid:26996332 |
| Petrelli F et al. | Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice. | 2016 | Eur. J. Pharmacol. | pmid:27663279 |
| Gerhardt P et al. | [Male urethritis]. | 2016 | Ann Dermatol Venereol | pmid:27776813 |
| Dupin N et al. | [Chlamydia trachomatis]. | 2016 | Ann Dermatol Venereol | pmid:27773503 |
| Gong L et al. | Clinical effect of treating secondary asthma attacks of children Mycoplasma pneumoniae with combined therapy of montelukast and azithromycin. | 2016 | Eur Rev Med Pharmacol Sci | pmid:28051240 |
| Xiridou M et al. | Cost-Effectiveness of Dual Antimicrobial Therapy for Gonococcal Infections Among Men Who Have Sex With Men in the Netherlands. | 2016 | Sex Transm Dis | pmid:27513379 |
| Mitjà O et al. | Mass Treatment with Single-Dose Azithromycin for Yaws. | 2016 | N. Engl. J. Med. | pmid:27626525 |
| Cheng GS et al. | Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant. | 2016 | Ann Am Thorac Soc | pmid:27513368 |
| Kobuchi S et al. | Transport of Azithromycin into Extravascular Space in Rats. | 2016 | Antimicrob. Agents Chemother. | pmid:27600045 |
| Marks M et al. | Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma. | 2016 | PLoS Negl Trop Dis | pmid:27551787 |
| Samson C et al. | Long-term effects of azithromycin in patients with cystic fibrosis. | 2016 | Respir Med | pmid:27492507 |
| Akram FE et al. | A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27530257 |
| Caumes E et al. | [Donovanosis (granuloma inguinale)]. | 2016 | Ann Dermatol Venereol | pmid:27773509 |
| O'Farrell N | Control of gonorrhoea and chlamydia in the UK. | 2016 | Lancet | pmid:27477165 |
| Zhu XH et al. | Viral and Bacterial Etiology of Acute Diarrhea among Children under 5 Years of Age in Wuhan, China. | 2016 | Chin. Med. J. | pmid:27503019 |
| Zhao M et al. | Comparison of minocycline and azithromycin for the treatment of mild scrub typhus in northern China. | 2016 | Int. J. Antimicrob. Agents | pmid:27449540 |
| Dukers-Muijrers NH et al. | Design of the FemCure study: prospective multicentre study on the transmission of genital and extra-genital Chlamydia trachomatis infections in women receiving routine care. | 2016 | BMC Infect. Dis. | pmid:27502928 |
| Huang SW et al. | Azithromycin impairs TLR7 signaling in dendritic cells and improves the severity of imiquimod-induced psoriasis-like skin inflammation in mice. | 2016 | J. Dermatol. Sci. | pmid:27449383 |
| Yoshioka D et al. | Efficacy of β-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal Pneumonia. | 2016 | Antimicrob. Agents Chemother. | pmid:27480866 |
| Jacobsson S et al. | WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014. | 2016 | J. Antimicrob. Chemother. | pmid:27432597 |
| Jeong BH et al. | Peak Plasma Concentration of Azithromycin and Treatment Responses in Mycobacterium avium Complex Lung Disease. | 2016 | Antimicrob. Agents Chemother. | pmid:27480854 |
| de Zwart L et al. | Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling. | 2016 | Clin. Pharmacol. Ther. | pmid:27367453 |
| Abeles SR et al. | Microbial diversity in individuals and their household contacts following typical antibiotic courses. | 2016 | Microbiome | pmid:27473422 |
| Lockington D | Oral azithromycin and blepharitis: symptoms and signs improve, so where are the publications? | 2016 | Clin. Experiment. Ophthalmol. | pmid:27356302 |
| Zhu B et al. | High Resistance to Azithromycin in Clinical Samples from Patients with Sexually Transmitted Diseases in Guangxi Zhuang Autonomous Region, China. | 2016 | PLoS ONE | pmid:27467164 |
| Miyake H et al. | Meibomian Gland Dysfunction Model in Hairless Mice Fed a Special Diet With Limited Lipid Content. | 2016 | Invest. Ophthalmol. Vis. Sci. | pmid:27327582 |
| Kobbernagel HE et al. | Study protocol, rationale and recruitment in a European multi-centre randomized controlled trial to determine the efficacy and safety of azithromycin maintenance therapy for 6Â months in primary ciliary dyskinesia. | 2016 | BMC Pulm Med | pmid:27450411 |
| Sacks HS | In older adults, macrolide antibiotics were not linked to increased risk for ventricular arrhythmia. | 2016 | Ann. Intern. Med. | pmid:27323264 |
| Liu Y et al. | Influence of Omega 3 and 6 Fatty Acids on Human Meibomian Gland Epithelial Cells. | 2016 | Cornea | pmid:27227397 |
| Noda AA et al. | First Report of the 23S rRNA Gene A2058G Point Mutation Associated With Macrolide Resistance in Treponema pallidum From Syphilis Patients in Cuba. | 2016 | Sex Transm Dis | pmid:27100771 |
| Haas AN et al. | Predictors of clinical outcomes after periodontal treatment of aggressive periodontitis: 12-month randomized trial. | 2016 | Braz Oral Res | pmid:27223128 |
| Itaqui SR et al. | In Vitro Synergism between Azithromycin or Terbinafine and Topical Antimicrobial Agents against Pythium insidiosum. | 2016 | Antimicrob. Agents Chemother. | pmid:27216049 |
| Wang Z and Meenach SA | Synthesis and Characterization of Nanocomposite Microparticles (nCmP) for the Treatment of Cystic Fibrosis-Related Infections. | 2016 | Pharm. Res. | pmid:27091030 |
| Phong NC et al. | In Vivo Efficacy and Tolerability of Artesunate-Azithromycin for the Treatment of Falciparum Malaria in Vietnam. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27215294 |
| Ab Rahman N et al. | Antibiotic prescribing in public and private practice: a cross-sectional study in primary care clinics in Malaysia. | 2016 | BMC Infect. Dis. | pmid:27188538 |
| Brown J et al. | Shigellosis: high rates of antibiotic resistance necessitate new treatment recommendations. | 2016 | Med. J. Aust. | pmid:27078594 |
| Ramaiah B et al. | High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice. | 2016 | Daru | pmid:27150818 |
| Rajabi O et al. | Topical liposomal azithromycin in the treatment of acute cutaneous leishmaniasis. | 2016 | Dermatol Ther | pmid:27073044 |
| Geisler WM et al. | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144856 |
| Dunn AL et al. | Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl. | 2016 | Lab Med | pmid:26984830 |
| Yelenich-Huss MJ et al. | Ozena in Immigrants of Differing Backgrounds. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27114295 |
| Saini H et al. | Antimicrobial and antifouling efficacy of urinary catheters impregnated with a combination of macrolide and fluoroquinolone antibiotics against Pseudomonas aeruginosa. | 2016 | Biofouling | pmid:26982572 |
| Vermeersch K et al. | The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial. | 2016 | Int J Chron Obstruct Pulmon Dis | pmid:27099485 |
| Levy V et al. | A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea. | 2016 | Sex Transm Dis | pmid:26967304 |
| Guo Y et al. | Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. | 2016 | Viruses | pmid:27089359 |
| Gülses A and Ayna M | Re: Comparison of Azithromycin and Amoxicillin Before Dental Implant Placement: An Exploratory Study of Bioavailability and Resolution of Postoperative Inflammation. | 2016 | J. Periodontol. | pmid:26962889 |
| Hu J et al. | Streptococcus pneumoniae and Haemophilus influenzae type b carriage in Chinese children aged 12-18 months in Shanghai, China: a cross-sectional study. | 2016 | BMC Infect. Dis. | pmid:27080523 |
| McClure KS and Cameron ST | An audit of expedited treatment for uncomplicated Chlamydia trachomatis index cases at the community pharmacy. | 2016 | Int J STD AIDS | pmid:26945591 |
| Liang JY et al. | Azithromycin-resistant Neisseria gonorrhoeae isolates in Guangzhou, China (2009-2013): coevolution with decreased susceptibilities to ceftriaxone and genetic characteristics. | 2016 | BMC Infect. Dis. | pmid:27080231 |
| McCarthy M | No link between macrolide antibiotics and ventricular arrhythmias, study finds. | 2016 | BMJ | pmid:26905692 |
| Ward E and Duff P | A comparison of 3 antibiotic regimens for prevention of postcesarean endometritis: an historical cohort study. | 2016 | Am. J. Obstet. Gynecol. | pmid:26901276 |
| Kadota T et al. | Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease. | 2016 | BMC Infect. Dis. | pmid:26818764 |
| Wladis EJ et al. | Oral Antibiotics for Meibomian Gland-Related Ocular Surface Disease: A Report by the American Academy of Ophthalmology. | 2016 | Ophthalmology | pmid:26707417 |
| Deshpande D et al. | Azithromycin Dose To Maximize Efficacy and Suppress Acquired Drug Resistance in Pulmonary Mycobacterium avium Disease. | 2016 | Antimicrob. Agents Chemother. | pmid:26810646 |
| Stokholm J et al. | Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial. | 2016 | Lancet Respir Med | pmid:26704020 |
| Swatton JE et al. | Impact of Azithromycin on the Quorum Sensing-Controlled Proteome of Pseudomonas aeruginosa. | 2016 | PLoS ONE | pmid:26808156 |
| Afshar M et al. | Azithromycin use and outcomes in severe sepsis patients with and without pneumonia. | 2016 | J Crit Care | pmid:26803186 |
| Lenehan PJ et al. | An evaluation strategy for potential QTc prolongation with chronic azithromycin therapy in cystic fibrosis. | 2016 | J. Cyst. Fibros. | pmid:26698953 |
| Lee H et al. | New treatment options for infections caused by increasingly antimicrobial-resistant Neisseria gonorrhoeae. | 2016 | Expert Rev Anti Infect Ther | pmid:26690658 |
| Nakajima T et al. | Microbiological and Clinical Effects of Sitafloxacin and Azithromycin in Periodontitis Patients Receiving Supportive Periodontal Therapy. | 2016 | Antimicrob. Agents Chemother. | pmid:26729495 |
| Jentsch HF et al. | Nonsurgical therapy of chronic periodontitis with adjunctive systemic azithromycin or amoxicillin/metronidazole. | 2016 | Clin Oral Investig | pmid:26685849 |
| Slade J et al. | Chlamydial Pre-Infection Protects from Subsequent Herpes Simplex Virus-2 Challenge in a Murine Vaginal Super-Infection Model. | 2016 | PLoS ONE | pmid:26726882 |
| Lococo F et al. | Hemoptysis and Progressive Dyspnea in a 67-Year-Old Woman with History of Renal Transplantation. | 2016 | Am. J. Respir. Crit. Care Med. | pmid:26681504 |
| Mukai S et al. | Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. | 2016 | Int. J. Oncol. | pmid:26718641 |
| Miyagawa T et al. | Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-α. | 2016 | Arch. Oral Biol. | pmid:26655749 |
| Smith DJ et al. | Pseudomonas aeruginosa antibiotic resistance in Australian cystic fibrosis centres. | 2016 | Respirology | pmid:26711802 |
| Lübbert C | Antimicrobial therapy of acute diarrhoea: a clinical review. | 2016 | Expert Rev Anti Infect Ther | pmid:26641310 |
| Lee SJ et al. | Maternal azithromycin administration eradicates intra-amniotic Ureaplasma infection: The first human case report. | 2016 | J Obstet Gynaecol | pmid:26634623 |
| Martin I et al. | Decline in Decreased Cephalosporin Susceptibility and Increase in Azithromycin Resistance in Neisseria gonorrhoeae, Canada. | 2016 | Emerging Infect. Dis. | pmid:26689114 |
| Höh H et al. | [MALT Lymphoma of the Conjunctiva in a 13-year old Child--5-Year Relapse-free Follow-up Following Antibiotic Treatment]. | 2016 | Klin Monbl Augenheilkd | pmid:26609671 |
| Luo Q et al. | Surface plasmon resonance sensor for antibiotics detection based on photo-initiated polymerization molecularly imprinted array. | 2016 | Talanta | pmid:27769483 |
| Al-Hity A and Lockington D | Oral azithromycin as the systemic treatment of choice in the treatment of meibomian gland disease. | 2016 | Clin. Experiment. Ophthalmol. | pmid:26441357 |
| Ruttens D et al. | Prophylactic Azithromycin Therapy After Lung Transplantation: Post hoc Analysis of a Randomized Controlled Trial. | 2016 | Am. J. Transplant. | pmid:26372728 |
| Wu TS et al. | Postcesarean section wound infection caused by Mycobacterium massiliense. | 2016 | J Microbiol Immunol Infect | pmid:26350122 |
| Unger HW et al. | Azithromycin-containing intermittent preventive treatment in pregnancy affects gestational weight gain, an important predictor of birthweight in Papua New Guinea - an exploratory analysis. | 2016 | Matern Child Nutr | pmid:26373537 |
| Zhang Z et al. | Clinical effect of azithromycin as an adjunct to non-surgical treatment of chronic periodontitis: a meta-analysis of randomized controlled clinical trials. | 2016 | J. Periodont. Res. | pmid:26362529 |
| Chang Y et al. | Factors Influencing the HPLC Determination for Related Substances of Azithromycin. | 2016 | J Chromatogr Sci | pmid:26324196 |
| Caspi M et al. | A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. | 2016 | J. Mol. Med. | pmid:26620677 |
| Li SQ et al. | Establishment of a new animal model of azithromycin-induced liver injury and study the molecular pathological change during the process. | 2016 | Hum Exp Toxicol | pmid:26205530 |
| Nappe TM et al. | Stevens-Johnson syndrome after treatment with azithromycin: an uncommon culprit. | 2016 | Am J Emerg Med | pmid:26194400 |
| Derad I et al. | Hypertension and mild chronic kidney disease persist following severe haemolytic uraemic syndrome caused by Shiga toxin-producing Escherichia coli O104:H4 in adults. | 2016 | Nephrol. Dial. Transplant. | pmid:26180049 |
| Steeples LR et al. | Real-time PCR using the 529 bp repeat element for the diagnosis of atypical ocular toxoplasmosis. | 2016 | Br J Ophthalmol | pmid:26174811 |
| Arora N et al. | Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster. | 2016 | Nat Microbiol | pmid:27918528 |
| Retallack H et al. | Zika virus cell tropism in the developing human brain and inhibition by azithromycin. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:27911847 |
| Brittain C et al. | Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial. | 2016 | Trials | pmid:27881151 |
| Shimizu T and Suzaki H | Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. | 2016 | Auris Nasus Larynx | pmid:26441370 |
| Libois A and De Wit S | Which empiric syndromic treatment for urethritis? | 2016 | Int J STD AIDS | pmid:27794143 |
| Gaudreau C et al. | Shigella flexneri with Ciprofloxacin Resistance and Reduced Azithromycin Susceptibility, Canada, 2015. | 2016 | Emerging Infect. Dis. | pmid:27767915 |
| Narita M et al. | Antimicrobial Susceptibility of Microorganisms Isolated from Periapical Periodontitis Lesions. | 2016 | Bull. Tokyo Dent. Coll. | pmid:27665691 |
| Dombrowski JC and Batteiger BE | Reconsidering the Use of Azithromycin for Chlamydial Urethritis. | 2016 | Sex Transm Dis | pmid:27626187 |