Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Sidhu H et al. | Risk assessment of biosolids-borne ciprofloxacin and azithromycin. | 2019 | Sci. Total Environ. | pmid:30463165 |
Sidhu H et al. | Plant toxicity and accumulation of biosolids-borne ciprofloxacin and azithromycin. | 2019 | Sci. Total Environ. | pmid:30340267 |
Sidhu H et al. | Retention-release of ciprofloxacin and azithromycin in biosolids and biosolids-amended soils. | 2019 | Sci. Total Environ. | pmid:30196217 |
Sidhu H et al. | Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: Microbial toxicity and earthworm responses. | 2019 | Sci. Total Environ. | pmid:30195128 |
Å majs D and PospÃÅ¡ilová P | Macrolide resistance in yaws. | 2018 | Lancet | pmid:29428184 |
Mitjà O et al. | Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study. | 2018 | Lancet | pmid:29428183 |
Brereton CJ et al. | Is gentamicin safe and effective for severe community-acquired pneumonia? An 8-year retrospective cohort study. | 2018 | Int. J. Antimicrob. Agents | pmid:29410326 |
Ting CY and Shahdadpuri R | Fuchs syndrome: a case of fever, mucositis and conjunctivitis. | 2018 | BMJ Case Rep | pmid:29378740 |
Huang S et al. | Human babesiosis in Southeast China: A case report. | 2018 | Int. J. Infect. Dis. | pmid:29355731 |
Jenson A et al. | Patient-centered communication of community treatment assistants in Tanzania predicts coverage of future mass drug administration for trachoma. | 2018 | Patient Educ Couns | pmid:29329726 |
Sarathchandran P et al. | infection presenting as stroke and meningoencephalitis with aortic and subclavian aneurysms without pulmonary involvement. | 2018 | BMJ Case Rep | pmid:29326371 |
Mascarenhas TR et al. | Tick-borne illness after transplantation: Case and review. | 2018 | Transpl Infect Dis | pmid:29277955 |
Oldenburg CE et al. | Comparison of Mass Azithromycin Coverage Targets of Children in Niger: A Cluster-Randomized Trachoma Trial. | 2018 | Am. J. Trop. Med. Hyg. | pmid:29260659 |
Medeiros PHQS et al. | Molecular characterization of virulence and antimicrobial resistance profile of Shigella species isolated from children with moderate to severe diarrhea in northeastern Brazil. | 2018 | Diagn. Microbiol. Infect. Dis. | pmid:29217418 |
Casas-Maldonado F | Bronchiectasis and Azithromycin. | 2018 | Arch. Bronconeumol. | pmid:28757281 |
Zhao L et al. | Trends in antimicrobial resistance in Neisseria gonorrhoeae and molecular characteristics of N. gonorrhoeae with decreased susceptibility to ceftriaxone in Shandong, China, 2007 to 2014. | 2018 | Int. J. Antimicrob. Agents | pmid:28729124 |
Bakshi SS | In reference to 'Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion'. | 2018 | Eur Arch Otorhinolaryngol | pmid:28612316 |
Revello R et al. | Prediction of chorioamnionitis in cases of intraamniotic infection by ureaplasma urealyticum in women with very preterm premature rupture of membranes or preterm labour. | 2018 | J. Matern. Fetal. Neonatal. Med. | pmid:28502201 |
Hassan KS and Al-Khadouri G | Pneumonia with Worsening Pleural Effusion Despite Treatment with Appropriate Antimicrobials: Case report. | 2018 | Sultan Qaboos Univ Med J | pmid:30210860 |
Williams PCM and Berkley JA | Guidelines for the management of paediatric cholera infection: a systematic review of the evidence. | 2018 | Paediatr Int Child Health | pmid:29790841 |
Al-Darraji A et al. | Azithromycin therapy reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction: Potential therapeutic targets in ischemic heart disease. | 2018 | PLoS ONE | pmid:30001416 |
Glanternik JR et al. | A Cluster of Cases of Babesia microti Among Neonates Traced to a Single Unit of Donor Blood. | 2018 | Pediatr. Infect. Dis. J. | pmid:28945680 |
Cai X et al. | Anti-N-methyl-D-aspartate receptor encephalitis associated with acute Toxoplasma gondii infection: A case report. | 2018 | Medicine (Baltimore) | pmid:29443773 |
Yang D et al. | The timing of azithromycin treatment is not associated with the clinical prognosis of childhood Mycoplasma pneumoniae pneumonia in high macrolide-resistant prevalence settings. | 2018 | PLoS ONE | pmid:29377957 |
Morales A et al. | Microbiological and clinical effects of probiotics and antibiotics on nonsurgical treatment of chronic periodontitis: a randomized placebo- controlled trial with 9-month follow-up. | 2018 | J Appl Oral Sci | pmid:29364340 |
Buder S et al. | Antimicrobial resistance of Neisseria gonorrhoeae in Germany: low levels of cephalosporin resistance, but high azithromycin resistance. | 2018 | BMC Infect. Dis. | pmid:29343220 |
Crooks MG et al. | How does azithromycin improve asthma exacerbations? | 2018 | Lancet | pmid:29323653 |
Gibson PG | How does azithromycin improve asthma exacerbations? - Author's reply. | 2018 | Lancet | pmid:29323652 |
Sanchez Garcia D et al. | Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) - A comparison with lysosomotropic drugs. | 2018 | Chem. Biol. Interact. | pmid:29248446 |
Vermillion Maier ML and Tjeerdema RS | Azithromycin sorption and biodegradation in a simulated California river system. | 2018 | Chemosphere | pmid:29031188 |
Obaro S | Azithromycin and Childhood Mortality in Africa. | 2018 | N. Engl. J. Med. | pmid:30284804 |
Michelow IC and Sánchez PJ | Azithromycin and Childhood Mortality in Africa. | 2018 | N. Engl. J. Med. | pmid:30284803 |
Cutler T et al. | Azithromycin and Childhood Mortality in Africa. | 2018 | N. Engl. J. Med. | pmid:30284802 |
Keenan JD et al. | Azithromycin and Childhood Mortality in Africa. | 2018 | N. Engl. J. Med. | pmid:30281987 |
El Sayed I et al. | Antibiotics for treating scrub typhus. | 2018 | Cochrane Database Syst Rev | pmid:30246875 |
Goyal V et al. | Amoxicillin-clavulanate versus azithromycin for respiratory exacerbations in children with bronchiectasis (BEST-2): a multicentre, double-blind, non-inferiority, randomised controlled trial. | 2018 | Lancet | pmid:30241722 |
Iguidbashian JP et al. | and coinfection in the setting of ulcerative colitis. | 2018 | BMJ Case Rep | pmid:29880626 |
Lendermon EA et al. | Azithromycin Fails to Prevent Accelerated Airway Obliteration in T-bet Mouse Lung Allograft Recipients. | 2018 | Transplant. Proc. | pmid:29880387 |
Lam-Franco L et al. | IL-1α and MMP-9 Tear Levels of Patients with Active Ocular Rosacea before and after Treatment with Systemic Azithromycin or Doxycycline. | 2018 | Ophthalmic Res. | pmid:29874670 |
Saita MG et al. | pH-Dependent stability of azithromycin in aqueous solution and structure identification of two new degradation products. | 2018 | J Pharm Biomed Anal | pmid:29860178 |
Naderi N et al. | Long-term azithromycin therapy to reduce acute exacerbations in patients with severe chronic obstructive pulmonary disease. | 2018 | Respir Med | pmid:29724384 |
Zmora N et al. | Open label comparative trial of mono versus dual antibiotic therapy for Typhoid Fever in adults. | 2018 | PLoS Negl Trop Dis | pmid:29684022 |
Wei W et al. | MPEG-PCL Copolymeric Micelles for Encapsulation of Azithromycin. | 2018 | AAPS PharmSciTech | pmid:29675667 |
Barge L et al. | Transient immune-mediated agranulocytosis following infection. | 2018 | BMJ Case Rep | pmid:29669774 |
Baker KS et al. | Horizontal antimicrobial resistance transfer drives epidemics of multiple Shigella species. | 2018 | Nat Commun | pmid:29654279 |
Ganesh R et al. | Clinical profile and outcome of children with scrub typhus from Chennai, South India. | 2018 | Eur. J. Pediatr. | pmid:29637374 |
Papp JR et al. | Accuracy and reproducibility of the Etest to detect drug-resistant Neisseria gonorrhoeae to contemporary treatment. | 2018 | J. Med. Microbiol. | pmid:29219803 |
Deguchi T et al. | Macrolide and fluoroquinolone resistance is uncommon in clinical strains of Chlamydia trachomatis. | 2018 | J. Infect. Chemother. | pmid:29627327 |
Smith-Norowitz TA et al. | Doxycycline suppresses Chlamydia pneumoniae induced interferon-gamma responses in peripheral blood mononuclear cells in children with allergic asthma. | 2018 | J. Infect. Chemother. | pmid:29615379 |
Rim JH et al. | Recent Increase in the Incidence of TEM-135 β-Lactamase-harboring Neisseria gonorrhoeae in Korea. | 2018 | Ann Lab Med | pmid:29611382 |