Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Lung Diseases D008171 37 associated lipids
Sarcoidosis D012507 13 associated lipids
Hyperglycemia D006943 21 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Skin Neoplasms D012878 12 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Osteitis D010000 10 associated lipids
Dog Diseases D004283 5 associated lipids
Osteomyelitis D010019 10 associated lipids
Coronary Disease D003327 70 associated lipids
Pancreatitis D010195 10 associated lipids
Acne Vulgaris D000152 35 associated lipids
Skin Ulcer D012883 6 associated lipids
Eyelid Diseases D005141 4 associated lipids
Multiple Myeloma D009101 13 associated lipids
Pain, Postoperative D010149 13 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Corneal Opacity D003318 3 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Eye Diseases D005128 12 associated lipids
Arteriosclerosis D001161 86 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Sardana K et al. An observational study of the efficacy of azithromycin in erythema annulare centrifugum. 2018 Clin. Exp. Dermatol. pmid:29297941
Bakar O et al. The effect of azithromycin on reactive oxygen species in rosacea. 2007 Clin. Exp. Dermatol. pmid:17244346
Trevisi P et al. Toxic pustuloderma associated with azithromycin. 1994 Clin. Exp. Dermatol. pmid:8033402
Fuentelsaz V et al. Rosacea fulminans in pregnancy: successful treatment with azithromycin. 2011 Clin. Exp. Dermatol. pmid:21714808
López-Lerma I et al. Occupational airborne contact dermatitis from azithromycin. 2009 Clin. Exp. Dermatol. pmid:19486052
Chaudhry SI et al. A rash on the back. Diagnosis: confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud. 2006 Clin. Exp. Dermatol. pmid:16901326
Gruber F et al. Treatment of confluent and reticulated papillomatosis with azithromycin. 1998 Clin. Exp. Dermatol. pmid:9894368
Weckmann M et al. Treatment with rhDNase in patients with cystic fibrosis alters in-vitro CHIT-1 activity of isolated leucocytes. 2016 Clin. Exp. Immunol. pmid:27324468
Iwamoto S et al. The effect of azithromycin on the maturation and function of murine bone marrow-derived dendritic cells. 2011 Clin. Exp. Immunol. pmid:22059997
Buehring I et al. Chronic sinusitis refractory to standard management in patients with humoral immunodeficiencies. 1997 Clin. Exp. Immunol. pmid:9328124
Iwamoto S et al. Efficacy of azithromycin in preventing lethal graft-versus-host disease. 2013 Clin. Exp. Immunol. pmid:23379441
Sugiyama K et al. Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells. 2007 Clin. Exp. Immunol. pmid:17302905
Rotschild M et al. Autoantibodies against bactericidal/permeability-increasing protein (BPI-ANCA) in cystic fibrosis patients treated with azithromycin. 2005 Clin. Exp. Med. pmid:16096858
Jones S et al. Trachoma in Far North Queensland: an example of poor population health practice. 2013 Clin. Experiment. Ophthalmol. pmid:23145782
Lockington D Oral azithromycin and blepharitis: symptoms and signs improve, so where are the publications? 2016 Clin. Experiment. Ophthalmol. pmid:27356302
Shah SA et al. Meibomian gland dysfunction: azithromycin and objective improvement in outcomes in posterior blepharitis. 2016 Clin. Experiment. Ophthalmol. pmid:27314917
Heriot WJ et al. Ocular involvement in a patient with Legionella longbeachae 1 infection. 2014 Clin. Experiment. Ophthalmol. pmid:24650007
Al-Hity A and Lockington D Oral azithromycin as the systemic treatment of choice in the treatment of meibomian gland disease. 2016 Clin. Experiment. Ophthalmol. pmid:26441357
Martinez MA et al. Clinical and histologic features of azithromycin-induced liver injury. 2015 Clin. Gastroenterol. Hepatol. pmid:25111234
Arnez M Antibiotic treatment of children with erythema migrans. 2007 Clin. Infect. Dis. pmid:17366464
Kaplan EL et al. Macrolide therapy of group A streptococcal pharyngitis: 10 days of macrolide therapy (clarithromycin) is more effective in streptococcal eradication than 5 days (azithromycin). 2001 Clin. Infect. Dis. pmid:11360224
Griffith DE et al. Varying dosages of rifabutin affect white blood cell and platelet counts in human immunodeficiency virus--negative patients who are receiving multidrug regimens for pulmonary Mycobacterium avium complex disease. 1996 Clin. Infect. Dis. pmid:8953085
Hicks LA et al. US outpatient antibiotic prescribing variation according to geography, patient population, and provider specialty in 2011. 2015 Clin. Infect. Dis. pmid:25747410
Gershengorn HB et al. The association of antibiotic treatment regimen and hospital mortality in patients hospitalized with Legionella pneumonia. 2015 Clin. Infect. Dis. pmid:25722195
Plouffe JF et al. Azithromycin in the treatment of Legionella pneumonia requiring hospitalization. 2003 Clin. Infect. Dis. pmid:14614670
Kober MB and Mason BA Colonization of the female genital tract by resistant Ureaplasma urealyticum treated successfully with azithromycin. 1998 Clin. Infect. Dis. pmid:9709898
Adal KA et al. Photo quiz. Bacillary angiomatosis. 1995 Clin. Infect. Dis. pmid:7727641
Bissessor M et al. Macrolide resistance and azithromycin failure in a Mycoplasma genitalium-infected cohort and response of azithromycin failures to alternative antibiotic regimens. 2015 Clin. Infect. Dis. pmid:25537875
Doan T et al. Gut Microbial Diversity in Antibiotic-Naive Children After Systemic Antibiotic Exposure: A Randomized Controlled Trial. 2017 Clin. Infect. Dis. pmid:28402408
Tribble D et al. Efficacy of azithromycin for typhoid fever. 1995 Clin. Infect. Dis. pmid:8645805
Kain KC et al. Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens. 2001 Clin. Infect. Dis. pmid:11418883
Lisby G et al. Bacteremia and meningitis caused by a macrolide-sensitive strain of Streptococcus pneumoniae during treatment with azithromycin. 2001 Clin. Infect. Dis. pmid:11438918
Taylor WR et al. Malaria prophylaxis using azithromycin: a double-blind, placebo-controlled trial in Irian Jaya, Indonesia. 1999 Clin. Infect. Dis. pmid:10028075
Bissessor M et al. Persistence of Neisseria gonorrhoeae DNA following treatment for pharyngeal and rectal gonorrhea is influenced by antibiotic susceptibility and reinfection. 2015 Clin. Infect. Dis. pmid:25371490
Reichenbach J et al. Actinomyces in chronic granulomatous disease: an emerging and unanticipated pathogen. 2009 Clin. Infect. Dis. pmid:19874205
Katz AR et al. Neisseria gonorrhoeae with high-level resistance to azithromycin: case report of the first isolate identified in the United States. 2012 Clin. Infect. Dis. pmid:22184617
Goins WP et al. A comparison of 2 strategies to prevent infection following pertussis exposure in vaccinated healthcare personnel. 2012 Clin. Infect. Dis. pmid:22238169
Genton B and D'Acremont V Evidence of efficacy is not enough to develop recommendations: antibiotics for treatment of traveler's diarrhea. 2007 Clin. Infect. Dis. pmid:17479953
Park J et al. Progression and Treatment Outcomes of Lung Disease Caused by Mycobacterium abscessus and Mycobacterium massiliense. 2017 Clin. Infect. Dis. pmid:28011609
Read TR et al. Azithromycin 1.5g Over 5 Days Compared to 1g Single Dose in Urethral Mycoplasma genitalium: Impact on Treatment Outcome and Resistance. 2017 Clin. Infect. Dis. pmid:28011607
White AC Treatment of Early Syphilis in HIV: What Do We Really Know? 2017 Clin. Infect. Dis. pmid:28362951
Amza A et al. A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children. 2017 Clin. Infect. Dis. pmid:27956455
Halpern MT and Cifaldi MA Is azithromycin the first-choice macrolide for treatment of community-acquired pneumonia? 2004 Clin. Infect. Dis. pmid:15206068
Wind CM et al. Decreased Azithromycin Susceptibility of Neisseria gonorrhoeae Isolates in Patients Recently Treated with Azithromycin. 2017 Clin. Infect. Dis. pmid:28510723
Shanks GD et al. Single dose of azithromycin or three-day course of ciprofloxacin as therapy for epidemic dysentery in Kenya. Acute Dysentery Study Group. 1999 Clin. Infect. Dis. pmid:10589921
Kirkcaldy RD et al. The efficacy and safety of gentamicin plus azithromycin and gemifloxacin plus azithromycin as treatment of uncomplicated gonorrhea. 2014 Clin. Infect. Dis. pmid:25031289
Guerrant RL et al. Thinking deeper about important mass treatment trials. 2012 Clin. Infect. Dis. pmid:22431805
Falagas ME and Klempner MS Babesiosis in patients with AIDS: a chronic infection presenting as fever of unknown origin. 1996 Clin. Infect. Dis. pmid:8722936
Murphy GS et al. Ciprofloxacin- and azithromycin-resistant Campylobacter causing traveler's diarrhea in U.S. troops deployed to Thailand in 1994. 1996 Clin. Infect. Dis. pmid:8722958
Guchev IA et al. Two regimens of azithromycin prophylaxis against community-acquired respiratory and skin/soft-tissue infections among military trainees. 2004 Clin. Infect. Dis. pmid:15095213
Martin DH et al. Comparison of azithromycin and ceftriaxone for the treatment of chancroid. 1995 Clin. Infect. Dis. pmid:8562752
Ghaffar F et al. Effects of amoxicillin/clavulanate or azithromycin on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae in children with acute otitis media. 2000 Clin. Infect. Dis. pmid:11049764
Kelley MA et al. Breakthrough pneumococcal bacteremia in patients being treated with azithromycin and clarithromycin. 2000 Clin. Infect. Dis. pmid:11049784
Adachi JA et al. Empirical antimicrobial therapy for traveler's diarrhea. 2000 Clin. Infect. Dis. pmid:11049792
Liao CH et al. Nutritionally variant streptococcal infections at a University Hospital in Taiwan: disease emergence and high prevalence of beta-lactam and macrolide resistance. 2004 Clin. Infect. Dis. pmid:14727223
Frenck RW et al. Azithromycin versus ceftriaxone for the treatment of uncomplicated typhoid fever in children. 2000 Clin. Infect. Dis. pmid:11073741
Meltzer E et al. A large outbreak of Salmonella Paratyphi A infection among israeli travelers to Nepal. 2014 Clin. Infect. Dis. pmid:24198224
Tseng AL et al. Azithromycin-related ototoxicity in patients infected with human immunodeficiency virus. 1997 Clin. Infect. Dis. pmid:8994766
Dunne M et al. A randomized, double-blind trial comparing azithromycin and clarithromycin in the treatment of disseminated Mycobacterium avium infection in patients with human immunodeficiency virus. 2000 Clin. Infect. Dis. pmid:11073759
Adimora AA Treatment of uncomplicated genital Chlamydia trachomatis infections in adults. 2002 Clin. Infect. Dis. pmid:12353204
Augenbraun MH Treatment of syphilis 2001: nonpregnant adults. 2002 Clin. Infect. Dis. pmid:12353205
Gill DA et al. Complete elimination is a difficult goal for trachoma programs in severely affected communities. 2008 Clin. Infect. Dis. pmid:18194094
Hoge CW et al. Trends in antibiotic resistance among diarrheal pathogens isolated in Thailand over 15 years. 1998 Clin. Infect. Dis. pmid:9502453
Kuschner RA et al. Use of azithromycin for the treatment of Campylobacter enteritis in travelers to Thailand, an area where ciprofloxacin resistance is prevalent. 1995 Clin. Infect. Dis. pmid:8527539
Keenan JD et al. Ribosomal RNA evidence of ocular Chlamydia trachomatis infection following 3 annual mass azithromycin distributions in communities with highly prevalent trachoma. 2012 Clin. Infect. Dis. pmid:22095569
Kaplan EL et al. Reduced ability of penicillin to eradicate ingested group A streptococci from epithelial cells: clinical and pathogenetic implications. 2006 Clin. Infect. Dis. pmid:17083011
Malhotra-Kumar S and Goossens H Mass azithromycin distribution and emerging resistance: taking a minimum harms approach. 2013 Clin. Infect. Dis. pmid:23487372
Coles CL et al. Mass distribution of azithromycin for trachoma control is associated with increased risk of azithromycin-resistant Streptococcus pneumoniae carriage in young children 6 months after treatment. 2013 Clin. Infect. Dis. pmid:23487375
Weber JT and Johnson RE New treatments for Chlamydia trachomatis genital infection. 1995 Clin. Infect. Dis. pmid:7795110
Joloba ML et al. Pneumococcal conjugate vaccine serotypes of Streptococcus pneumoniae isolates and the antimicrobial susceptibility of such isolates in children with otitis media. 2001 Clin. Infect. Dis. pmid:11588694
Sanders JW et al. Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey. 2007 Clin. Infect. Dis. pmid:18688944
Sirinavin S et al. Norfloxacin and azithromycin for treatment of nontyphoidal salmonella carriers. 2003 Clin. Infect. Dis. pmid:12942401
Black S Changing epidemiology of invasive pneumococcal disease: a complicated story. 2008 Clin. Infect. Dis. pmid:18627248
Rocha JL Correct dose of azithromycin for patients scheduled to undergo dental procedures. 2003 Clin. Infect. Dis. pmid:12955653
Spooner K et al. Azithromcyin might not protect against Treponema pallidum infection or reactivation in HIV type 1-infected patients. 2005 Clin. Infect. Dis. pmid:16007551
Sánchez F et al. Is azithromycin the first-choice macrolide for treatment of community-acquired pneumonia? 2003 Clin. Infect. Dis. pmid:12746768
Deguchi T et al. Multidrug-Resistant Mycoplasma genitalium Is Increasing. 2016 Clin. Infect. Dis. pmid:26494825
Kong FY et al. Reply to Deguchi et al. 2016 Clin. Infect. Dis. pmid:26494824
Benson CA Treatment of disseminated disease due to the Mycobacterium avium complex in patients with AIDS. 1994 Clin. Infect. Dis. pmid:8204776
Kalonji LM et al. Invasive Salmonella Infections at Multiple Surveillance Sites in the Democratic Republic of the Congo, 2011-2014. 2015 Clin. Infect. Dis. pmid:26449951
Choi EK and Pai H Azithromycin therapy for scrub typhus during pregnancy. 1998 Clin. Infect. Dis. pmid:9868680
Cascio A et al. Clarithromycin versus azithromycin in the treatment of Mediterranean spotted fever in children: a randomized controlled trial. 2002 Clin. Infect. Dis. pmid:11740701
Watson JR et al. Healthcare Claims Data: An Underutilized Tool for Pediatric Outpatient Antimicrobial Stewardship. 2017 Clin. Infect. Dis. pmid:28329388
Thompson CN et al. Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal. 2017 Clin. Infect. Dis. pmid:28329181
Horner PJ Editorial Commentary: Mycoplasma genitalium and Declining Treatment Efficacy of Azithromycin 1 g: What Can We Do? 2015 Clin. Infect. Dis. pmid:26240204
Lau A et al. The Efficacy of Azithromycin for the Treatment of Genital Mycoplasma genitalium: A Systematic Review and Meta-analysis. 2015 Clin. Infect. Dis. pmid:26240201
Gray GC et al. Weekly oral azithromycin as prophylaxis for agents causing acute respiratory disease. 1998 Clin. Infect. Dis. pmid:9455517
Andersen SL et al. Successful double-blinded, randomized, placebo-controlled field trial of azithromycin and doxycycline as prophylaxis for malaria in western Kenya. 1998 Clin. Infect. Dis. pmid:9455524
Buyck JM et al. Increased susceptibility of Pseudomonas aeruginosa to macrolides and ketolides in eukaryotic cell culture media and biological fluids due to decreased expression of oprM and increased outer-membrane permeability. 2012 Clin. Infect. Dis. pmid:22573850
Chia JK et al. Azithromycin for the treatment of cat-scratch disease. 1998 Clin. Infect. Dis. pmid:9455538
Peterson J and Treadway G Impact of community-based azithromycin treatment of trachoma on carriage and resistance of Streptococcus pneumoniae. 1998 Clin. Infect. Dis. pmid:9455579
Mena LA et al. A randomized comparison of azithromycin and doxycycline for the treatment of Mycoplasma genitalium-positive urethritis in men. 2009 Clin. Infect. Dis. pmid:19438399
Jensen JS Single-dose azithromycin treatment for Mycoplasma genitalium-positive urethritis: best but not good enough. 2009 Clin. Infect. Dis. pmid:19438400
Manhart LE et al. Standard treatment regimens for nongonococcal urethritis have similar but declining cure rates: a randomized controlled trial. 2013 Clin. Infect. Dis. pmid:23223595
Griffith DE et al. Azithromycin activity against Mycobacterium avium complex lung disease in patients who were not infected with human immunodeficiency virus. 1996 Clin. Infect. Dis. pmid:8922790
Ward TT et al. Randomized, open-label trial of azithromycin plus ethambutol vs. clarithromycin plus ethambutol as therapy for Mycobacterium avium complex bacteremia in patients with human immunodeficiency virus infection. Veterans Affairs HIV Research Consortium. 1998 Clin. Infect. Dis. pmid:9827282
Phillips P et al. Azithromycin prophylaxis for Mycobacterium avium complex during the era of highly active antiretroviral therapy: evaluation of a provincial program. 2002 Clin. Infect. Dis. pmid:11774085
Mitchell SJ et al. Azithromycin-resistant syphilis infection: San Francisco, California, 2000-2004. 2006 Clin. Infect. Dis. pmid:16392078
Griffith DE et al. Azithromycin-containing regimens for treatment of Mycobacterium avium complex lung disease. 2001 Clin. Infect. Dis. pmid:11340525
Tan JS et al. Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila. 2001 Clin. Infect. Dis. pmid:11340527