Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Å majs D and PospÃÅ¡ilová P | Macrolide resistance in yaws. | 2018 | Lancet | pmid:29428184 |
Mitjà O et al. | Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study. | 2018 | Lancet | pmid:29428183 |
Brereton CJ et al. | Is gentamicin safe and effective for severe community-acquired pneumonia? An 8-year retrospective cohort study. | 2018 | Int. J. Antimicrob. Agents | pmid:29410326 |
Ting CY and Shahdadpuri R | Fuchs syndrome: a case of fever, mucositis and conjunctivitis. | 2018 | BMJ Case Rep | pmid:29378740 |
Huang S et al. | Human babesiosis in Southeast China: A case report. | 2018 | Int. J. Infect. Dis. | pmid:29355731 |
Jenson A et al. | Patient-centered communication of community treatment assistants in Tanzania predicts coverage of future mass drug administration for trachoma. | 2018 | Patient Educ Couns | pmid:29329726 |
Casas-Maldonado F | Bronchiectasis and Azithromycin. | 2018 | Arch. Bronconeumol. | pmid:28757281 |
Zhao L et al. | Trends in antimicrobial resistance in Neisseria gonorrhoeae and molecular characteristics of N. gonorrhoeae with decreased susceptibility to ceftriaxone in Shandong, China, 2007 to 2014. | 2018 | Int. J. Antimicrob. Agents | pmid:28729124 |
Weston EJ et al. | Adherence to CDC Recommendations for the Treatment of Uncomplicated Gonorrhea - STD Surveillance Network, United States, 2016. | 2018 | MMWR Morb. Mortal. Wkly. Rep. | pmid:29698384 |
Keenan JD et al. | Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa. | 2018 | N. Engl. J. Med. | pmid:29694816 |
Hassan KS and Al-Khadouri G | Pneumonia with Worsening Pleural Effusion Despite Treatment with Appropriate Antimicrobials: Case report. | 2018 | Sultan Qaboos Univ Med J | pmid:30210860 |
Williams PCM and Berkley JA | Guidelines for the management of paediatric cholera infection: a systematic review of the evidence. | 2018 | Paediatr Int Child Health | pmid:29790841 |
Al-Darraji A et al. | Azithromycin therapy reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction: Potential therapeutic targets in ischemic heart disease. | 2018 | PLoS ONE | pmid:30001416 |
Glanternik JR et al. | A Cluster of Cases of Babesia microti Among Neonates Traced to a Single Unit of Donor Blood. | 2018 | Pediatr. Infect. Dis. J. | pmid:28945680 |
Vermillion Maier ML and Tjeerdema RS | Azithromycin sorption and biodegradation in a simulated California river system. | 2018 | Chemosphere | pmid:29031188 |
Tada H et al. | The effects of Lactobacillus reuteri probiotics combined with azithromycin on peri-implantitis: A randomized placebo-controlled study. | 2018 | J Prosthodont Res | pmid:28756115 |
Iguidbashian JP et al. | and coinfection in the setting of ulcerative colitis. | 2018 | BMJ Case Rep | pmid:29880626 |
Lendermon EA et al. | Azithromycin Fails to Prevent Accelerated Airway Obliteration in T-bet Mouse Lung Allograft Recipients. | 2018 | Transplant. Proc. | pmid:29880387 |
Lam-Franco L et al. | IL-1α and MMP-9 Tear Levels of Patients with Active Ocular Rosacea before and after Treatment with Systemic Azithromycin or Doxycycline. | 2018 | Ophthalmic Res. | pmid:29874670 |
Saita MG et al. | pH-Dependent stability of azithromycin in aqueous solution and structure identification of two new degradation products. | 2018 | J Pharm Biomed Anal | pmid:29860178 |