Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Donowitz GR | Tissue-directed antibiotics and intracellular parasites: complex interaction of phagocytes, pathogens, and drugs. | 1994 | Clin. Infect. Dis. | pmid:7893881 |
| Beale AS and Upshon PA | Characteristics of murine model of genital infection with Chlamydia trachomatis and effects of therapy with tetracyclines, amoxicillin-clavulanic acid, or azithromycin. | 1994 | Antimicrob. Agents Chemother. | pmid:7811001 |
| Verdon MS et al. | Pilot study of azithromycin for treatment of primary and secondary syphilis. | 1994 | Clin. Infect. Dis. | pmid:7811868 |
| Chiarini F et al. | Chlamydia trachomatis genitourinary infections: laboratory diagnosis and therapeutic aspects. Evaluation of in vitro and in vivo effectiveness of azithromycin. | 1994 | J Chemother | pmid:7830100 |
| Schwab JC et al. | Localization of azithromycin in Toxoplasma gondii-infected cells. | 1994 | Antimicrob. Agents Chemother. | pmid:7979295 |
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| Rodriguez WJ and Wiedermann BL | The role of newer oral cephalosporins, fluoroquinolones, and macrolides in the treatment of pediatric infections. | 1994 | Adv Pediatr Infect Dis | pmid:8123221 |
| SteingrÃmsson O et al. | Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men. | 1994 Jan-Feb | Sex Transm Dis | pmid:8140488 |
| Tyndall MW et al. | Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. | 1994 Jul-Aug | Sex Transm Dis | pmid:7974076 |
| Lang R et al. | Therapeutic effects of roxithromycin and azithromycin in experimental murine brucellosis. | 1994 Jul-Aug | Chemotherapy | pmid:8082413 |
| Handsfield HH et al. | Multicenter trial of single-dose azithromycin vs. ceftriaxone in the treatment of uncomplicated gonorrhea. Azithromycin Gonorrhea Study Group. | 1994 Mar-Apr | Sex Transm Dis | pmid:9071422 |
| Sher AA et al. | [Interactions in the system of copper ion-azalide (azithromycin)]. | 1994 Sep-Oct | Antibiot. Khimioter. | pmid:7695446 |
| Debets-Ossenkopp YJ et al. | Effect of an acidic environment on the susceptibility of Helicobacter pylori to trospectomycin and other antimicrobial agents. | 1995 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:7649202 |
| Adal KA et al. | Photo quiz. Bacillary angiomatosis. | 1995 | Clin. Infect. Dis. | pmid:7727641 |
| Bermudez LE et al. | Efficacy of azithromycin and rifabutin in preventing infection by Mycobacterium avium complex in beige mice. | 1995 | J. Antimicrob. Chemother. | pmid:8591938 |
| Domingo S et al. | Comparative activity of azithromycin and doxycycline against Brucella spp. infection in mice. | 1995 | J. Antimicrob. Chemother. | pmid:8591939 |
| Nash KA and Inderlied CB | Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated disease. | 1995 | Antimicrob. Agents Chemother. | pmid:8592991 |
| Bohte R et al. | Levels of azithromycin and alpha-1 acid glycoprotein in serum in patients with community-acquired pneumonia. | 1995 | Antimicrob. Agents Chemother. | pmid:8593024 |
| Tribble D et al. | Efficacy of azithromycin for typhoid fever. | 1995 | Clin. Infect. Dis. | pmid:8645805 |
| Strickman D et al. | In vitro effectiveness of azithromycin against doxycycline-resistant and -susceptible strains of Rickettsia tsutsugamushi, etiologic agent of scrub typhus. | 1995 | Antimicrob. Agents Chemother. | pmid:8585717 |
| Kuzman I et al. | Azithromycin for treatment of community acquired pneumonia caused by Legionella pneumophila: a retrospective study. | 1995 | Scand. J. Infect. Dis. | pmid:8588143 |
| Gill CJ et al. | In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin. | 1995 | J. Antibiot. | pmid:7490222 |
| Silvestri M et al. | Azithromycin induces in vitro a time-dependent increase in the intracellular killing of Staphylococcus aureus by human polymorphonuclear leucocytes without damaging phagocytes. | 1995 | J. Antimicrob. Chemother. | pmid:8821593 |
| Patton DL et al. | The activity of azithromycin on the infectivity of Chlamydia trachomatis in human amniotic cells. | 1995 | J. Antimicrob. Chemother. | pmid:8821594 |
| Spangler SK et al. | Susceptibilities of 201 anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin by oxyrase agar dilution and E test methodologies. | 1995 | J. Clin. Microbiol. | pmid:7615756 |
| Lo KK et al. | An open non-comparative pilot study with azithromycin in the treatment of non-gonococcal urethritis in the sexually transmitted disease clinics in Hong Kong. | 1995 | Ann. Acad. Med. Singap. | pmid:8849186 |
| Martin DH et al. | Comparison of azithromycin and ceftriaxone for the treatment of chancroid. | 1995 | Clin. Infect. Dis. | pmid:8562752 |
| Kieserman SP et al. | Streptococcal pharyngitis: alternative treatments. | 1995 | Ear Nose Throat J | pmid:8536567 |
| van Rijsoort-Vos JH et al. | In-vitro activity of a new quinolone (CP-99,219) compared with ciprofloxacin, pefloxacin, azithromycin and penicillin against Neisseria gonorrhoeae. | 1995 | J. Antimicrob. Chemother. | pmid:8537268 |
| Tissi L et al. | In vivo efficacy of azithromycin in treatment of systemic infection and septic arthritis induced by type IV group B Streptococcus strains in mice: comparative study with erythromycin and penicillin G. | 1995 | Antimicrob. Agents Chemother. | pmid:8540695 |
| Kuschner RA et al. | Use of azithromycin for the treatment of Campylobacter enteritis in travelers to Thailand, an area where ciprofloxacin resistance is prevalent. | 1995 | Clin. Infect. Dis. | pmid:8527539 |
| Beckers CJ et al. | Inhibition of cytoplasmic and organellar protein synthesis in Toxoplasma gondii. Implications for the target of macrolide antibiotics. | 1995 | J. Clin. Invest. | pmid:7814637 |
| Friis HM | [Azithromycin--an exciting new antibiotic]. | 1995 | Ugeskr. Laeg. | pmid:7831724 |
| Dessau RB | [Azithromycin]. | 1995 | Ugeskr. Laeg. | pmid:7831733 |
| al-Assi MT et al. | Azithromycin triple therapy for Helicobacter pylori infection: azithromycin, tetracycline, and bismuth. | 1995 | Am. J. Gastroenterol. | pmid:7872278 |
| Andersen SL et al. | Activity of azithromycin as a blood schizonticide against rodent and human plasmodia in vivo. | 1995 | Am. J. Trop. Med. Hyg. | pmid:7872444 |
| Bokemeyer B | [Combined therapy with azithromycin and omeprazole for the eradication of Helicobacter pylori]. | 1995 | Dtsch. Med. Wochenschr. | pmid:7555645 |
| Péc J et al. | [Treatment of chlamydia infections and a brief review of the problems]. | 1995 | Bratisl Lek Listy | pmid:7633932 |
| Bowden FJ et al. | Azithromycin and syphilis. | 1995 | Genitourin Med | pmid:7635501 |
| Yeo AE and Rieckmann KH | Increased antimalarial activity of azithromycin during prolonged exposure of Plasmodium falciparum in vitro. | 1995 | Int. J. Parasitol. | pmid:7635629 |
| Bamberger DM et al. | Azithromycin in an experimental Staphylococcus aureus abscess model. | 1995 | J. Antimicrob. Chemother. | pmid:7592175 |
| Adegbola RA et al. | Effect of azithromycin on pharyngeal microflora. | 1995 | Pediatr. Infect. Dis. J. | pmid:7603826 |
| Vartiovaara I | Living with Lyme. | 1995 | Lancet | pmid:7605437 |
| Fouda HG and Schneider RP | Quantitative determination of the antibiotic azithromycin in human serum by high-performance liquid chromatography (HPLC)-atmospheric pressure chemical ionization mass spectrometry: correlation with a standard HPLC-electrochemical method. | 1995 | Ther Drug Monit | pmid:7624907 |
| Goldstein EJ et al. | Comparative in vitro activities of azithromycin, Bay y 3118, levofloxacin, sparfloxacin, and 11 other oral antimicrobial agents against 194 aerobic and anaerobic bite wound isolates. | 1995 | Antimicrob. Agents Chemother. | pmid:7625795 |
| Barry AL et al. | Relative potencies of azithromycin, clarithromycin and five other orally administered antibiotics. | 1995 | J. Antimicrob. Chemother. | pmid:7628991 |
| Pascual A et al. | Factors affecting the intracellular accumulation and activity of azithromycin. | 1995 | J. Antimicrob. Chemother. | pmid:7768786 |
| Beghi G et al. | Efficacy and tolerability of azithromycin versus amoxicillin/clavulanic acid in acute purulent exacerbation of chronic bronchitis. | 1995 | J Chemother | pmid:7666122 |
| [New ways of antibiotic therapy]. | 1995 | Internist (Berl) | pmid:9431354 | |
| Bessette RE and Amsden GW | Treatment of non-HIV cryptosporidial diarrhea with azithromycin. | 1995 | Ann Pharmacother | pmid:8845560 |