Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Harris JA et al. | Safety and efficacy of azithromycin in the treatment of community-acquired pneumonia in children. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802626 |
| Nash MM and Zaltzman JS | Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients. | 1998 | Transplantation | pmid:9665078 |
| Dooley DP | Revisiting doxycycline. | 1998 | Arch. Intern. Med. | pmid:9665360 |
| Adair CD et al. | Chlamydia in pregnancy: a randomized trial of azithromycin and erythromycin. | 1998 | Obstet Gynecol | pmid:9469269 |
| Soepandi P et al. | The pattern of micro-organisms and the efficacy of new macrolide in acute lower respiratory tract infections. | 1998 | Respirology | pmid:9692520 |
| Fang X et al. | [Inhibitory activity of azithromycin on biofilm synthesis and synergism between azithromycin and fleroxacin on Pseudomonas aeruginosa in biofilms]. | 1998 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11360505 |
| Mitrokhin SD et al. | [Susceptibility of community-acquired pneumonia pathogens to azithromycin]. | 1998 | Antibiot. Khimioter. | pmid:9606504 |
| Thornton AC et al. | Prevention of experimental Haemophilus ducreyi infection: a randomized, controlled clinical trial. | 1998 | J. Infect. Dis. | pmid:9607840 |
| Palomar R et al. | Effectiveness and safety of azithromycin on the treatment of cyclosporine-induced gingival overgrowth. | 1998 | Nephron | pmid:9609470 |
| Kober MB and Mason BA | Colonization of the female genital tract by resistant Ureaplasma urealyticum treated successfully with azithromycin. | 1998 | Clin. Infect. Dis. | pmid:9709898 |
| Langtry HD and Balfour JA | Azithromycin. A review of its use in paediatric infectious diseases. | 1998 | Drugs | pmid:9711451 |
| Bianchi A et al. | Kinetics of Chlamydia trachomatis clearance in patients with azithromycin, as assessed by first void urine testing by PCR and transcription-mediated amplification. | 1998 | Sex Transm Dis | pmid:9713917 |
| Karpov OI et al. | [Comparative trial of 3-day azithromycin versus 10-day coamoxilav course efficacy in acute sinusitis]. | 1998 | Ter. Arkh. | pmid:9644751 |
| [6th München AIDS-Days. Azithromycin in HIV-associated opportunistic infections]. | 1998 | Internist (Berl) | pmid:9648000 | |
| Griffith DE et al. | Initial (6-month) results of three-times-weekly azithromycin in treatment regimens for Mycobacterium avium complex lung disease in human immunodeficiency virus-negative patients. | 1998 | J. Infect. Dis. | pmid:9652431 |
| Syphilis elimination seen as good HIV prevention. | 1998 | AIDS Alert | pmid:11365457 | |
| Azithro once a week for MAC. | 1998 | TreatmentUpdate | pmid:11365625 | |
| Haye R et al. | Azithromycin versus placebo in acute infectious rhinitis with clinical symptoms but without radiological signs of maxillary sinusitis. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9721958 |
| Wirnsberger GH et al. | Effect of antibiotic treatment with azithromycin on cyclosporine A-induced gingival hyperplasia among renal transplant recipients. | 1998 | Transplant. Proc. | pmid:9723411 |
| Blandizzi C et al. | Gastric mucosal distribution and clinical efficacy of azithromycin in patients with Helicobacter pylori related gastritis. | 1998 | J. Antimicrob. Chemother. | pmid:9700531 |
| O'Doherty B and Muller O | Randomized, multicentre study of the efficacy and tolerance of azithromycin versus clarithromycin in the treatment of adults with mild to moderate community-acquired pneumonia. Azithromycin Study Group. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10052544 |
| Van Bambeke F et al. | Lysosomal alterations induced in cultured rat fibroblasts by long-term exposure to low concentrations of azithromycin. | 1998 | J. Antimicrob. Chemother. | pmid:10052900 |
| Denis A and Agouridas C | Synthesis of 6-O-methyl-azithromycin and its ketolide analogue via Beckmann rearrangement of 9(E)-6-O-methyl-erythromycin oxime. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873555 |
| den Hollander JG et al. | Comparison of pharmacodynamics of azithromycin and erythromycin in vitro and in vivo. | 1998 | Antimicrob. Agents Chemother. | pmid:9527789 |
| Nowicki M et al. | Partial regression of advanced cyclosporin-induced gingival hyperplasia after treatment with azithromycin. A case report. | 1998 | Ann. Transplant. | pmid:10234432 |
| Gascón A et al. | Cryptosporidiosis in a haemodialysis patient with depressed CD4+ T cell count: successful treatment with azithromycin. | 1998 | Nephrol. Dial. Transplant. | pmid:9829506 |
| Sackoff J et al. | Prophylaxis for opportunistic infections among HIV-infected patients receiving medical care. | 1998 | J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. | pmid:9833748 |
| Hogan PA and Sheehan DJ | Macrolide susceptibility and beta-lactamase production among haemophilus influenzae isolates in the United States, 1996-1997. | 1998 | Antimicrob. Agents Chemother. | pmid:9835536 |
| Altschuler EL | Azithromycin, the multidrug-resistant protein, and cystic fibrosis. | 1998 | Lancet | pmid:9643772 |
| Tapsall JW et al. | Failure of azithromycin therapy in gonorrhea and discorrelation with laboratory test parameters. | 1998 | Sex Transm Dis | pmid:9858344 |
| Johnson DM et al. | Antimicrobial interactions of trovafloxacin and extended-spectrum cephalosporins or azithromycin tested against clinical isolates of Pseudomonas aeruginosa and Stenotrophomonas maltophilia. | 1998 | J. Antimicrob. Chemother. | pmid:9818765 |
| Mortensen JE et al. | In vitro activity of oral antimicrobial agents against clinical isolates of Pasteurella multocida. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9554176 |
| Hoppe JE and Bryskier A | In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). | 1998 | Antimicrob. Agents Chemother. | pmid:9559823 |
| Oldfield EC et al. | Once weekly azithromycin therapy for prevention of Mycobacterium avium complex infection in patients with AIDS: a randomized, double-blind, placebo-controlled multicenter trial. | 1998 | Clin. Infect. Dis. | pmid:9524832 |
| Fuentes F et al. | Postanitbiotic and sub-MIC effects of azithromycin and isepamicin against Staphylococcus aureus and Escherichia coli. | 1998 | Antimicrob. Agents Chemother. | pmid:9527796 |
| Kashuba AD and Amsden GW | Bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. | 1998 | Antimicrob. Agents Chemother. | pmid:9527816 |
| Socan M | Treatment of atypical pneumonia with azithromycin: comparison of a 5-day and a 3-day course. | 1998 | J Chemother | pmid:9531077 |
| Muhlestein JB et al. | Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. | 1998 | Circulation | pmid:9495296 |
| Woldtvedt BR et al. | Possible increased anticoagulation effect of warfarin induced by azithromycin. | 1998 | Ann Pharmacother | pmid:9496419 |
| Goldstein EJ et al. | Trovafloxacin compared with levofloxacin, ofloxacin, ciprofloxacin, azithromycin and clarithromycin against unusual aerobic and anaerobic human and animal bite-wound pathogens. | 1998 | J. Antimicrob. Chemother. | pmid:9578167 |
| Miller SR et al. | Delayed cellulitis associated with conservative therapy for breast cancer. | 1998 | J Surg Oncol | pmid:9579371 |
| Scaglione F and Rossoni G | Comparative anti-inflammatory effects of roxithromycin, azithromycin and clarithromycin. | 1998 | J. Antimicrob. Chemother. | pmid:9579712 |
| Kemper CA et al. | Immunomodulatory treatment of Mycobacterium avium complex bacteremia in patients with AIDS by use of recombinant granulocyte-macrophage colony-stimulating factor. | 1998 | J. Infect. Dis. | pmid:9534963 |
| Jucglà A et al. | The use of azithromycin for cyclosporin-induced gingival overgrowth. | 1998 | Br. J. Dermatol. | pmid:9536254 |
| Lilley LL and Guanci R | Distraction delays a dose. | 1998 | Am J Nurs | pmid:9473978 |
| Hahn DL et al. | Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9475566 |
| Dietz A et al. | [Macrolide antibiotic-induced vasculitis (Churg-Strauss syndrome)]. | 1998 | Laryngorhinootologie | pmid:9555706 |
| Levert H et al. | Azithromycin impact on neutrophil oxidative metabolism depends on exposure time. | 1998 | Inflammation | pmid:9561928 |
| Trevisani L et al. | A four-day low dose triple therapy regimen for the treatment of Helicobacter pylori infection. | 1998 | Am. J. Gastroenterol. | pmid:9517646 |
| Bowden FJ and Savage J | Donovanosis: treatment with azithromycin. | 1998 | Int J STD AIDS | pmid:9518024 |
| Champney WS and Burdine R | Macrolide antibiotic inhibition of translation and 50S ribosomal subunit assembly in methicillin-resistant Staphylococcus aureus cells. | 1998 | Microb. Drug Resist. | pmid:9818968 |
| Edelstein PH | Legionnaires' disease. | 1998 | N. Engl. J. Med. | pmid:9441231 |
| Bermudez LE et al. | Emergence of Mycobacterium avium populations resistant to macrolides during experimental chemotherapy. | 1998 | Antimicrob. Agents Chemother. | pmid:9449283 |
| Roblin PM and Hammerschlag MR | Microbiologic efficacy of azithromycin and susceptibilities to azithromycin of isolates of Chlamydia pneumoniae from adults and children with community-acquired pneumonia. | 1998 | Antimicrob. Agents Chemother. | pmid:9449287 |
| Jaffé A et al. | Long-term azithromycin may improve lung function in children with cystic fibrosis. | 1998 | Lancet | pmid:9482305 |
| Seelis RE and Dohmen W | [Short-term (6 days) eradication of Helicobacter pylori infection in the practice of a health insurance physician]. | 1998 | Dtsch. Med. Wochenschr. | pmid:9487294 |
| Thalhammer F et al. | Azithromycin-related toxic effects of digitoxin. | 1998 | Br J Clin Pharmacol | pmid:9489601 |
| Wawer MJ et al. | A randomized, community trial of intensive sexually transmitted disease control for AIDS prevention, Rakai, Uganda. | 1998 | AIDS | pmid:9677171 |
| Goldstein EJ et al. | Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated from skin and soft tissue infections in humans. | 1998 | Antimicrob. Agents Chemother. | pmid:9593139 |
| Spangler SK et al. | Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. | 1998 | Antimicrob. Agents Chemother. | pmid:9593160 |
| Turcinov T and Pepeljnjak S | Azithromycin potency determination: optimal conditions for microbiological diffusion method assay. | 1998 | J Pharm Biomed Anal | pmid:9682177 |
| Pankuch GA et al. | In vitro selection of resistance to four beta-lactams and azithromycin in Streptococcus pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9797225 |
| Dagan R et al. | Dynamics of pneumococcal nasopharyngeal colonization during the first days of antibiotic treatment in pediatric patients. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802628 |
| Can antibiotics prevent heart disease? | 1998 | Harv Heart Lett | pmid:9619136 | |
| Bass JW et al. | Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655532 |
| Klein JO | Clarithromycin and azithromycin. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655546 |
| Vcev A et al. | Omeprazole, azithromycin and either amoxycillin or metronidazole in eradication of Helicobacter pylori in duodenal ulcer patients. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663725 |
| Dagan R et al. | Early eradication of pathogens from middle ear fluid during antibiotic treatment of acute otitis media is associated with improved clinical outcome. | 1998 | Pediatr. Infect. Dis. J. | pmid:9779760 |
| Girgis N et al. | Azithromycin compared with rifampin for eradication of nasopharyngeal colonization by Neisseria meningitidis. | 1998 | Pediatr. Infect. Dis. J. | pmid:9779768 |
| Négrel AD and Mariotti SP | WHO alliance for the global elimination of blinding trachoma and the potential use of azithromycin. | 1998 | Int. J. Antimicrob. Agents | pmid:9916898 |
| Lacy MK et al. | Comparison of bactericidal activity after multidose administration of clarithromycin, azithromycin, and ceruroxime axetil against Streptococcus pneumoniae. | 1998 | Int. J. Antimicrob. Agents | pmid:9916901 |
| Cohen DA et al. | A school-based Chlamydia control program using DNA amplification technology. | 1998 | Pediatrics | pmid:9417165 |
| Fera MT et al. | Bactericidal activity of lansoprazole and three macrolides against Helicobacter pylori strains tested by the time-kill kinetic method. | 1998 | Int. J. Antimicrob. Agents | pmid:9916902 |
| Klausner JD et al. | Enhanced control of an outbreak of Mycoplasma pneumoniae pneumonia with azithromycin prophylaxis. | 1998 | J. Infect. Dis. | pmid:9419183 |
| Jakob-Sölder B et al. | Treatment of pediatric patients with acute group A beta-hemolytic streptococcal tonsillopharyngitis. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9923529 |
| Rothova A et al. | Azithromycin for ocular toxoplasmosis. | 1998 | Br J Ophthalmol | pmid:9924338 |
| Apseloff G et al. | Comparison of azithromycin and clarithromycin in their interactions with rifabutin in healthy volunteers. | 1998 | J Clin Pharmacol | pmid:9753212 |
| Yanami J et al. | [Tumor neovascularization inhibiting and tumor proliferation and metastasis suppressing actions of 14-, 15-, and 16-member ring macrolides]. | 1998 | Jpn J Antibiot | pmid:9597489 |
| Shih CM and Wang CC | Ability of azithromycin in combination with quinine for the elimination of babesial infection in humans. | 1998 | Am. J. Trop. Med. Hyg. | pmid:9790419 |
| Inoue K et al. | [Inhibitory effects of macrolide antibiotics on infiltration and proliferation of lung cancer cell lines, A-549 and SBC-3]. | 1998 | Jpn J Antibiot | pmid:9597493 |
| Nakayama I et al. | [Transport of azithromycin into infected tissue observed by macro- and microautoradiography]. | 1998 | Jpn J Antibiot | pmid:9597509 |
| Davis TM | Adverse effects of antimalarial prophylactic drugs: an important consideration in the risk-benefit equation. | 1998 | Ann Pharmacother | pmid:9793605 |
| Dionisio D et al. | Chronic cryptosporidiosis in patients with AIDS: stable remission and possible eradication after long-term, low dose azithromycin. | 1998 | J. Clin. Pathol. | pmid:9602688 |
| Hillis SD et al. | Doxycycline and azithromycin for prevention of chlamydial persistence or recurrence one month after treatment in women. A use-effectiveness study in public health settings. | 1998 | Sex Transm Dis | pmid:9437777 |
| Sánchez F et al. | [Treatment of pneumonia caused by Legionella with azithromycin]. | 1998 | Rev Esp Quimioter | pmid:9795300 |
| Bayoumi AM and Redelmeier DA | Preventing Mycobacterium avium complex in patients who are using protease inhibitors: a cost-effectiveness analysis. | 1998 | AIDS | pmid:9727572 |
| Moyle GJ et al. | Once weekly azithromycin as prophylaxis against recurrence of non-tuberculous mycobacterial infections in HIV-1-positive individuals. | 1998 | AIDS | pmid:9727581 |
| Gray GC et al. | Weekly oral azithromycin as prophylaxis for agents causing acute respiratory disease. | 1998 | Clin. Infect. Dis. | pmid:9455517 |
| Smith NH et al. | Combination drug therapy for cryptosporidiosis in AIDS. | 1998 | J. Infect. Dis. | pmid:9728569 |
| Andersen SL et al. | Successful double-blinded, randomized, placebo-controlled field trial of azithromycin and doxycycline as prophylaxis for malaria in western Kenya. | 1998 | Clin. Infect. Dis. | pmid:9455524 |
| Hammerschlag MR et al. | Treatment of neonatal chlamydial conjunctivitis with azithromycin. | 1998 | Pediatr. Infect. Dis. J. | pmid:9849993 |
| Chia JK et al. | Azithromycin for the treatment of cat-scratch disease. | 1998 | Clin. Infect. Dis. | pmid:9455538 |
| Raines DA et al. | Simultaneous high-performance liquid chromatography analysis of azithromycin and two of its metabolites in human tears and plasma. | 1998 | Ther Drug Monit | pmid:9853988 |
| Alder JD et al. | Dynamics of clarithromycin and azithromycin efficacies against experimental Haemophilus influenzae pulmonary infection. | 1998 | Antimicrob. Agents Chemother. | pmid:9736568 |
| Yeo AE et al. | Indirect inhibition by antibiotics of nucleotide and deoxynucleotide biosynthesis in Plasmodium falciparum. | 1998 | Southeast Asian J. Trop. Med. Public Health | pmid:9740262 |
| Mainardi JL et al. | Cat scratch disease due to Bartonella henselae serotype Marseille (Swiss cat) in a seronegative patient. | 1998 | J. Clin. Microbiol. | pmid:9742017 |
| Gruber F et al. | Treatment of confluent and reticulated papillomatosis with azithromycin. | 1998 | Clin. Exp. Dermatol. | pmid:9894368 |
| Carbon C | Pharmacodynamics of macrolides, azalides, and streptogramins: effect on extracellular pathogens. | 1998 | Clin. Infect. Dis. | pmid:9675445 |
| Greenblatt DJ et al. | Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. | 1998 | Clin. Pharmacol. Ther. | pmid:9757151 |
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