| MeSH term | MeSH ID | Detail |
|---|---|---|
| Respiratory Tract Infections | D012141 | 4 associated lipids |
| Agammaglobulinemia | D000361 | 4 associated lipids |
| Corneal Edema | D015715 | 3 associated lipids |
| Tuberculosis, Pulmonary | D014397 | 18 associated lipids |
| HIV Seropositivity | D006679 | 15 associated lipids |
| Endophthalmitis | D009877 | 12 associated lipids |
| Enteritis | D004751 | 8 associated lipids |
| Leprosy | D007918 | 8 associated lipids |
| Periapical Periodontitis | D010485 | 6 associated lipids |
| Bronchial Hyperreactivity | D016535 | 15 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Katz KA et al. | Molecular epidemiology of syphilis--San Francisco, 2004-2007. | 2010 | Sex Transm Dis | pmid:20601928 |
| Tapsall JW et al. | Failure of azithromycin therapy in gonorrhea and discorrelation with laboratory test parameters. | 1998 | Sex Transm Dis | pmid:9858344 |
| Blandford JM and Gift TL | The cost-effectiveness of single-dose azithromycin for treatment of incubating syphilis. | 2003 | Sex Transm Dis | pmid:12782951 |
| Dillon JA et al. | Reduced susceptibility to azithromycin and high percentages of penicillin and tetracycline resistance in Neisseria gonorrhoeae isolates from Manaus, Brazil, 1998. | 2001 | Sex Transm Dis | pmid:11518869 |
| Dombrowski JC and Batteiger BE | Reconsidering the Use of Azithromycin for Chlamydial Urethritis. | 2016 | Sex Transm Dis | pmid:27626187 |
| Latif AS et al. | Antimicrobial susceptibility in isolates from five sentinel surveillance sites in Zimbabwe, 2015-2016. | 2018 | Sex Transm Infect | pmid:28476914 |
| Niccolai LM et al. | Behavioural sources of repeat Chlamydia trachomatis infections: importance of different sex partners. | 2011 | Sex Transm Infect | pmid:21212380 |
| Khosropour CM et al. | Efficacy of standard therapies against Ureaplasma species and persistence among men with non-gonococcal urethritis enrolled in a randomised controlled trial. | 2015 | Sex Transm Infect | pmid:25616607 |
| Gundevia Z et al. | Positivity at test of cure following first-line treatment for genital Mycoplasma genitalium: follow-up of a clinical cohort. | 2015 | Sex Transm Infect | pmid:25096921 |
| National guideline for the management of donovanosis (granuloma inguinale). Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616381 | |
| Pasternack R et al. | Follow up of treatment: an integral part of the control of Chlamydia trachomatis infections. | 1999 | Sex Transm Infect | pmid:10448353 |
| Cabeza J et al. | Feasibility of Chlamydia trachomatis screening and treatment in pregnant women in Lima, Peru: a prospective study in two large urban hospitals. | 2015 | Sex Transm Infect | pmid:25107711 |
| Romoren M et al. | Costs and health consequences of chlamydia management strategies among pregnant women in sub-Saharan Africa. | 2007 | Sex Transm Infect | pmid:17932126 |
| Hathorn E et al. | What is the most appropriate treatment for rectal Chlamydia trachomatis infection? | 2016 | Sex Transm Infect | pmid:26892930 |
| Hathorn E et al. | What is the appropriate treatment for the management of rectal Chlamydia trachomatis in men and women? | 2012 | Sex Transm Infect | pmid:22517887 |
| Oud EV et al. | Pitfalls in the diagnosis and management of inguinal lymphogranuloma venereum: important lessons from a case series. | 2014 | Sex Transm Infect | pmid:24787368 |
| Chisholm SA et al. | An outbreak of high-level azithromycin resistant Neisseria gonorrhoeae in England. | 2016 | Sex Transm Infect | pmid:26601852 |
| Thakur SD et al. | Molecular epidemiology of Neisseria gonorrhoeae isolates from Saskatchewan, Canada: utility of NG-MAST in predicting antimicrobial susceptibility regionally. | 2014 | Sex Transm Infect | pmid:24503900 |
| Khosropour CM et al. | Suboptimal adherence to doxycycline and treatment outcomes among men with non-gonococcal urethritis: a prospective cohort study. | 2014 | Sex Transm Infect | pmid:24106340 |
| Horner P and Saunders J | Should azithromycin 1 g be abandoned as a treatment for bacterial STIs? The case for and against. | 2017 | Sex Transm Infect | pmid:27418572 |