| MeSH term | MeSH ID | Detail |
|---|---|---|
| Retinal Hemorrhage | D012166 | 3 associated lipids |
| Mycobacterium Infections, Nontuberculous | D009165 | 8 associated lipids |
| Dyspnea | D004417 | 10 associated lipids |
| Angina, Unstable | D000789 | 14 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
| Keratitis | D007634 | 7 associated lipids |
| Stevens-Johnson Syndrome | D013262 | 3 associated lipids |
| Food Hypersensitivity | D005512 | 7 associated lipids |
| Lymphadenitis | D008199 | 8 associated lipids |
| Drug Eruptions | D003875 | 30 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kikuchi Y et al. | Hyperoxia exaggerates bacterial dissemination and lethality in Pseudomonas aeruginosa pneumonia. | 2009 | Pulm Pharmacol Ther | pmid:19162211 |
| Yamada K et al. | Azithromycin inhibits MUC5AC induction via multidrug-resistant Acinetobacter baumannii in human airway epithelial cells. | 2014 | Pulm Pharmacol Ther | pmid:24910464 |
| Morinaga Y et al. | Azithromycin, clarithromycin and telithromycin inhibit MUC5AC induction by Chlamydophila pneumoniae in airway epithelial cells. | 2009 | Pulm Pharmacol Ther | pmid:19716898 |
| Blasi F et al. | Long-term azithromycin use in patients with chronic obstructive pulmonary disease and tracheostomy. | 2010 | Pulm Pharmacol Ther | pmid:20025989 |
| Kang JY et al. | Long-term azithromycin ameliorates not only airway inflammation but also remodeling in a murine model of chronic asthma. | 2016 | Pulm Pharmacol Ther | pmid:26778828 |
| Kai T et al. | A low concentration of azithromycin inhibits the mRNA expression of N-acyl homoserine lactone synthesis enzymes, upstream of lasI or rhlI, in Pseudomonas aeruginosa. | 2009 | Pulm Pharmacol Ther | pmid:19393329 |
| Weinschenk K and Schwartz AC | A case report of closed-eye visual hallucinations. | 2011 Jan-Feb | Psychosomatics | pmid:21300201 |
| Serwin AB et al. | Gonorrhoea in 21st century--international and Polish situation. | 2014 | Przegl Epidemiol | pmid:25004630 |
| Biernat-Sudolska M et al. | [Voice on the treatment of ureaplasmas infections]. | 2009 | Przegl Epidemiol | pmid:19522233 |
| Szpakowski M and Szawłowski A | [Azithromycin (Sumamed) administration in empiric treatment of nosocomial pneumonia in upper digestive tract cancer patients]. | 2003 | Prz. Lek. | pmid:14575010 |
| Hanssens L et al. | The clinical benefits of long-term supplementation with omega-3 fatty acids in cystic fibrosis patients - A pilot study. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:27154364 |
| Bakheit AH et al. | Azithromycin. | 2014 | Profiles Drug Subst Excip Relat Methodol | pmid:24794904 |
| Bulkley D et al. | Revisiting the structures of several antibiotics bound to the bacterial ribosome. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20876130 |
| Davis AR et al. | Sequence selectivity of macrolide-induced translational attenuation. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25313041 |
| Retallack H et al. | Zika virus cell tropism in the developing human brain and inhibition by azithromycin. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:27911847 |
| Palmer NO | Pharmaceutical prescribing for children. Part 3. Antibiotic prescribing for children with odontogenic infections. | 2006 | Prim Dent Care | pmid:16393495 |
| James GD et al. | Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. | 2013 | Prim Care Respir J | pmid:23839240 |
| de Barbeyrac B | [Current aspects of Chlamydia trachomatis infection]. | 2013 | Presse Med | pmid:23419460 |
| Chanal J et al. | [What's new in the diagnosis and treatment of Neisseria gonorrhoeae]. | 2013 | Presse Med | pmid:23433914 |
| Yaws, a non-venereal treponemal infection. Still endemic in some parts of the world. | 2012 | Prescrire Int | pmid:23016260 | |
| Antibiotic therapy for trachoma. | 2009 | Prescrire Int | pmid:19750586 | |
| Intrauterine devices: antibiotic prophylaxis not necessary during insertion. | 2001 | Prescrire Int | pmid:11718174 | |
| Azithromycin: cardiovascular deaths. | 2013 | Prescrire Int | pmid:23383407 | |
| Gramellini D et al. | Mid-trimester amniocentesis and antibiotic prophylaxis. | 2007 | Prenat. Diagn. | pmid:17607664 |
| Giorlandino C et al. | Antibiotic prophylaxis before second-trimester genetic amniocentesis (APGA): a single-centre open randomised controlled trial. | 2009 | Prenat. Diagn. | pmid:19294678 |
| Miedinger D | [Dysuria and urethral discharge after travel abroad]. | 2006 | Praxis (Bern 1994) | pmid:16640179 |
| Steurer J | [In Process Citation]. | 2013 | Praxis (Bern 1994) | pmid:23919943 |
| Ryser C and Hasler P | [[Reactive arthritis]. | 2010 | Praxis (Bern 1994) | pmid:21049437 |
| Pollock E and Hasse B | [CME. Pertussis]]. | 2015 | Praxis (Bern 1994) | pmid:26331198 |
| Lanz J and Lautenschlager S | [CME Dermatology 16/Answer: Fever, Pustules and Joint Pain as Vacation Mementoes]. | 2018 | Praxis (Bern 1994) | pmid:29921188 |
| Steurer J | [Azithromycin in the treatment of pneumonia in the elderly is not dangerous]. | 2014 | Praxis (Bern 1994) | pmid:25228579 |
| Cramer CL et al. | Immunomodulatory indications of azithromycin in respiratory disease: a concise review for the clinician. | 2017 | Postgrad Med | pmid:28116959 |
| Barlam TF | Expedited treatment for partners of patients with gonorrhea and/or chlamydial infection: impact on rates of persistence or recurrence. | 2005 | Postgrad Med | pmid:15948359 |
| Rapp RP | Clinical and economic outcomes in respiratory tract infections: The impact of bacterial resistance. | 2002 | Postgrad Med | pmid:19667590 |
| Eagan L | Data on HIV infection in women expands. | 1999 | Posit Living | pmid:11367336 |
| Rifabutin for MAC questioned. | 1995 Jul-Aug | Posit Aware | pmid:11362571 | |
| D'Amico R | ICAAC update on opportunistic infections. | 1996 Nov-Dec | Posit Aware | pmid:11363974 |
| Faber M et al. | [Evaluation of clinical effectiveness and direct costs of azithromycin treatment for exacerbation of chronic obstructive pulmonary disease in hospitalized patients and ambulatory care]. | 2004 | Pol. Merkur. Lekarski | pmid:15524029 |
| Breborowicz A | [Azithromycin in the therapy of lower respiratory tract infection in children]. | 2008 | Pol. Merkur. Lekarski | pmid:19177779 |
| Breborowicz A | [Antibiotic therapy in asthma exacerbation and in cystic fibrosis in children]. | 2011 | Pol. Merkur. Lekarski | pmid:21675140 |
| Faber M et al. | [Comparative analysis of the effectiveness and costs of azithromycin and cefoperazone treatment of patients during COPD exacerbation]. | 2003 | Pol. Merkur. Lekarski | pmid:12712826 |
| Mammen MJ and Sethi S | Macrolide therapy for the prevention of acute exacerbations in chronic obstructive pulmonary disease. | 2012 | Pol. Arch. Med. Wewn. | pmid:22353707 |
| Zygner W et al. | Azithromycin in the treatment of a dog infected with Giardia intestinalis. | 2008 | Pol J Vet Sci | pmid:18942546 |
| Aktan B et al. | Effect of macrolide antibiotics on nitric oxide synthase and xanthine oxidase activities, and malondialdehyde level in erythrocyte of the guinea pigs with experimental otitis media with effusion. | 2003 Nov-Dec | Pol J Pharmacol | pmid:14730107 |
| Handrick W et al. | [Pulmonary infection due to Mycobacterium malmoense]. | 2005 | Pneumologie | pmid:15944898 |
| Köhler T et al. | Quorum sensing inhibition selects for virulence and cooperation in Pseudomonas aeruginosa. | 2010 | PLoS Pathog. | pmid:20463812 |
| Amran MY et al. | Investigation of encephalopathy caused by Shiga toxin 2c-producing Escherichia coli infection in mice. | 2013 | PLoS ONE | pmid:23516588 |
| Dukers-Muijrers NH et al. | Chlamydia trachomatis test-of-cure cannot be based on a single highly sensitive laboratory test taken at least 3 weeks after treatment. | 2012 | PLoS ONE | pmid:22470526 |
| Bradshaw CS et al. | Persistence of Mycoplasma genitalium following azithromycin therapy. | 2008 | PLoS ONE | pmid:18978939 |
| Zhu B et al. | High Resistance to Azithromycin in Clinical Samples from Patients with Sexually Transmitted Diseases in Guangxi Zhuang Autonomous Region, China. | 2016 | PLoS ONE | pmid:27467164 |