| MeSH term | MeSH ID | Detail |
|---|---|---|
| Retinal Hemorrhage | D012166 | 3 associated lipids |
| Mycobacterium Infections, Nontuberculous | D009165 | 8 associated lipids |
| Dyspnea | D004417 | 10 associated lipids |
| Angina, Unstable | D000789 | 14 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
| Keratitis | D007634 | 7 associated lipids |
| Stevens-Johnson Syndrome | D013262 | 3 associated lipids |
| Food Hypersensitivity | D005512 | 7 associated lipids |
| Lymphadenitis | D008199 | 8 associated lipids |
| Drug Eruptions | D003875 | 30 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| New DL et al. | Vertically transmitted babesiosis. | 1997 | J. Pediatr. | pmid:9255211 |
| Motohiro T et al. | [Clinical study on azithromycin in 10% fine granules and 100mg capsules in the field of pediatrics]. | 1997 | Jpn J Antibiot | pmid:9634360 |
| Rodvold KA et al. | Intrapulmonary steady-state concentrations of clarithromycin and azithromycin in healthy adult volunteers. | 1997 | Antimicrob. Agents Chemother. | pmid:9174209 |
| Khan WA et al. | Treatment of shigellosis: V. Comparison of azithromycin and ciprofloxacin. A double-blind, randomized, controlled trial. | 1997 | Ann. Intern. Med. | pmid:9139555 |
| Yasin RM et al. | Comparison of E-test with agar dilution methods in testing susceptibility of N. gonorrhoeae to azithromycin. | 1997 | Sex Transm Dis | pmid:9153733 |
| Pacifico L and Chiesa C | Efficacy of three-day azithromycin vs. ten-day penicillin V in the treatment of streptococcal pharyngitis. | 1997 | Pediatr. Infect. Dis. J. | pmid:9154566 |
| Fernandez-Obregon AC | Azithromycin for the treatment of acne. | 1997 | Int. J. Dermatol. | pmid:9159021 |
| Nightingale CH | Pharmacokinetics and pharmacodynamics of newer macrolides. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109156 |
| Block SL | Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109158 |
| Tarlow MJ et al. | Future indications for macrolides. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109159 |
| Dawson CR et al. | A comparison of oral azithromycin with topical oxytetracycline/polymyxin for the treatment of trachoma in children. | 1997 | Clin. Infect. Dis. | pmid:9114186 |
| Brown BA et al. | Relationship of adverse events to serum drug levels in patients receiving high-dose azithromycin for mycobacterial lung disease. | 1997 | Clin. Infect. Dis. | pmid:9142801 |
| Littlewood-Evans AJ et al. | Effect of combination therapy of rifampicin and azithromycin on TNF levels during a rat model of chronic osteomyelitis. | 1997 | J. Antimicrob. Chemother. | pmid:9145822 |
| Caselli M et al. | Short-term low-dose triple therapy with azithromycin, metronidazole and lansoprazole appears highly effective for the eradication of Helicobacter pylori. | 1997 | Eur J Gastroenterol Hepatol | pmid:9031898 |
| Arévalo Morles C et al. | Donovanosis: treatment with azithromycin. | 1997 | Int J STD AIDS | pmid:9043983 |
| Fuchs PC et al. | Effect of minor pH changes on the in-vitro activity of azithromycin and clarithromycin. | 1997 | J. Antimicrob. Chemother. | pmid:9044039 |
| Tursi A et al. | What is the best azithromycin-based therapy for Helicobacter pylori infection? | 1997 | J. Antimicrob. Chemother. | pmid:9044040 |
| Pendland SL et al. | Comparison of charcoal- and starch-based media for testing susceptibilities of Legionella species to macrolides, azalides, and fluoroquinolones. | 1997 | J. Clin. Microbiol. | pmid:9350781 |
| Hoepelman IM et al. | A short (3-day) course of azithromycin tablets versus a 10-day course of amoxycillin-clavulanic acid (co-amoxiclav) in the treatment of adults with lower respiratory tract infections and effects on long-term outcome. | 1997 | Int. J. Antimicrob. Agents | pmid:9552709 |
| Leri O et al. | [Effects of the triple therapy in the eradication of Helicobacter pylori: comparison of 3 different antibiotics]. | 1997 | Clin Ter | pmid:9528197 |
| Jepras RI et al. | Rapid assessment of antibiotic effects on Escherichia coli by bis-(1,3-dibutylbarbituric acid) trimethine oxonol and flow cytometry. | 1997 | Antimicrob. Agents Chemother. | pmid:9303401 |
| RodrÃguez-Bano J et al. | [Penetration of azithromycin into human neutrophils: effect of hydrogen peroxide production]. | 1997 | Enferm. Infecc. Microbiol. Clin. | pmid:9312278 |
| Gupta S et al. | Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarction. | 1997 | Circulation | pmid:9244203 |
| Vazifeh D et al. | Cellular accumulation of the new ketolide RU 64004 by human neutrophils: comparison with that of azithromycin and roxithromycin. | 1997 | Antimicrob. Agents Chemother. | pmid:9333032 |
| Nilius AM et al. | Variability in susceptibilities of Haemophilus influenzae to clarithromycin and azithromycin due to medium pH. | 1997 | J. Clin. Microbiol. | pmid:9163435 |
| Rajyaguru JM and Muszynski MJ | Enhancement of Burkholderia cepacia antimicrobial susceptibility by cationic compounds. | 1997 | J. Antimicrob. Chemother. | pmid:9338485 |
| Odenholt I et al. | Studies of the killing kinetics of benzylpenicillin, cefuroxime, azithromycin, and sparfloxacin on bacteria in the postantibiotic phase. | 1997 | Antimicrob. Agents Chemother. | pmid:9371360 |
| Jones RN and Biedenbach DJ | Antimicrobial activity of RU-66647, a new ketolide. | 1997 Jan-Feb | Diagn. Microbiol. Infect. Dis. | pmid:9127099 |
| Pollak PT and Slayter KL | Reduced serum theophylline concentrations after discontinuation of azithromycin: evidence for an unusual interaction. | 1997 Jul-Aug | Pharmacotherapy | pmid:9250566 |
| Grunden JW and Fisher KA | Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin. | 1997 Jul-Aug | Ann Pharmacother | pmid:9220046 |
| Tartaglione T | Treatment of nontuberculous mycobacterial infections: role of clarithromycin and azithromycin. | 1997 Jul-Aug | Clin Ther | pmid:9377608 |
| Shaio MF and Yang KD | Response of babesiosis to a combined regimen of quinine and azithromycin. | 1997 Mar-Apr | Trans. R. Soc. Trop. Med. Hyg. | pmid:9196774 |
| Stevens RC et al. | Pharmacokinetics of azithromycin after single- and multiple-doses in children. | 1997 Sep-Oct | Pharmacotherapy | pmid:9324176 |
| Destache CJ et al. | Microbiologic effect of bovine cerebrospinal fluid and azithromycin against Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. | 1997 Sep-Oct | Pharmacotherapy | pmid:9324186 |
| Lauvau DV and Verbist L | An open, multicentre, comparative study of the efficacy and safety of azithromycin and co-amoxiclav in the treatment of upper and lower respiratory tract infections in children. The Paediatric Azithromycin Study Group. | 1997 Sep-Oct | J. Int. Med. Res. | pmid:9364291 |
| Adair CD et al. | Chlamydia in pregnancy: a randomized trial of azithromycin and erythromycin. | 1998 | Obstet Gynecol | pmid:9469269 |
| Syphilis elimination seen as good HIV prevention. | 1998 | AIDS Alert | pmid:11365457 | |
| Haye R et al. | Azithromycin versus placebo in acute infectious rhinitis with clinical symptoms but without radiological signs of maxillary sinusitis. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9721958 |
| Wirnsberger GH et al. | Effect of antibiotic treatment with azithromycin on cyclosporine A-induced gingival hyperplasia among renal transplant recipients. | 1998 | Transplant. Proc. | pmid:9723411 |
| Blandizzi C et al. | Gastric mucosal distribution and clinical efficacy of azithromycin in patients with Helicobacter pylori related gastritis. | 1998 | J. Antimicrob. Chemother. | pmid:9700531 |
| Hogan PA and Sheehan DJ | Macrolide susceptibility and beta-lactamase production among haemophilus influenzae isolates in the United States, 1996-1997. | 1998 | Antimicrob. Agents Chemother. | pmid:9835536 |
| Mortensen JE et al. | In vitro activity of oral antimicrobial agents against clinical isolates of Pasteurella multocida. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9554176 |
| Muhlestein JB et al. | Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit model. | 1998 | Circulation | pmid:9495296 |
| Woldtvedt BR et al. | Possible increased anticoagulation effect of warfarin induced by azithromycin. | 1998 | Ann Pharmacother | pmid:9496419 |
| Champney WS and Burdine R | Azithromycin and clarithromycin inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells. | 1998 | Curr. Microbiol. | pmid:9425251 |
| Can antibiotics prevent heart disease? | 1998 | Harv Heart Lett | pmid:9619136 | |
| Bass JW et al. | Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655532 |
| Apseloff G et al. | Comparison of azithromycin and clarithromycin in their interactions with rifabutin in healthy volunteers. | 1998 | J Clin Pharmacol | pmid:9753212 |
| Shih CM and Wang CC | Ability of azithromycin in combination with quinine for the elimination of babesial infection in humans. | 1998 | Am. J. Trop. Med. Hyg. | pmid:9790419 |
| Greenblatt DJ et al. | Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. | 1998 | Clin. Pharmacol. Ther. | pmid:9757151 |