Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Chlamydial Pneumonia D061387 2 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Penile Diseases D010409 2 associated lipids
Toxoplasmosis, Ocular D014126 2 associated lipids
Pneumonia, Lipid D011017 2 associated lipids
Furunculosis D005667 2 associated lipids
Abdominal Abscess D018784 2 associated lipids
Typhoid Fever D014435 2 associated lipids
Pyomyositis D052880 2 associated lipids
Tooth Erosion D014077 2 associated lipids
Heartburn D006356 2 associated lipids
Elephantiasis D004604 2 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Tooth Mobility D014086 2 associated lipids
Hoarseness D006685 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Bites, Human D001734 2 associated lipids
Herpes Genitalis D006558 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Speer EM et al. Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro. 2018 PLoS ONE pmid:29715306
Chen QF and Zhang YW [Clinical effect of Saccharomyces boulardii powder combined with azithromycin sequential therapy in treatment of children with diarrhea secondary to Mycoplasma pneumoniae pneumonia]. 2018 Zhongguo Dang Dai Er Ke Za Zhi pmid:29429459
Kawamura K et al. Adjunctive therapy with azithromycin for moderate and severe acute respiratory distress syndrome: a retrospective, propensity score-matching analysis of prospectively collected data at a single center. 2018 Int. J. Antimicrob. Agents pmid:29501821
Bandyopadhyay R et al. Effectiveness of treatment regimens for Typhoid fever in the nalidixic acid-resistant S. typhi (NARST) era in South India. 2018 Trop Doct pmid:29495943
Mulugeta A et al. Coverage, social mobilization and challenges of mass Zithromax administration campaign in South and South East zones of Tigray, Northern Ethiopia: A cross sectional study. 2018 PLoS Negl Trop Dis pmid:29481558
Atkin PA and Simms ML Orofacial granulomatosis: an unsuccessful response to weekly azithromycin pulse therapy. 2018 Oral Surg Oral Med Oral Pathol Oral Radiol pmid:29477603
Liu YH et al. Antimicrobial susceptibilities and molecular typing of neisseria gonorrhoeae isolates at a medical centre in Taiwan, 2001-2013 with an emphasis on high rate of azithromycin resistance among the isolates. 2018 Int. J. Antimicrob. Agents pmid:29477549
Li B et al. The efficacy of azithromycin and doxycycline treatment for rectal chlamydial infection: a retrospective cohort study in South Australia. 2018 Intern Med J pmid:28967178
Bogdan M et al. In vitro effect of subminimal inhibitory concentrations of antibiotics on the biofilm formation ability of Acinetobacter baumannii clinical isolates. 2018 J Chemother pmid:28956494
Kamio K and Azuma A Diffuse panbronchiolitis: A fine road from the discovery of a disease to the establishment of treatment. 2018 Respir Investig pmid:30049592
Zikic A et al. Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis. 2018 J Pediatric Infect Dis Soc pmid:30007329
Morales A et al. Microbiological and clinical effects of probiotics and antibiotics on nonsurgical treatment of chronic periodontitis: a randomized placebo- controlled trial with 9-month follow-up. 2018 J Appl Oral Sci pmid:29364340
Buder S et al. Antimicrobial resistance of Neisseria gonorrhoeae in Germany: low levels of cephalosporin resistance, but high azithromycin resistance. 2018 BMC Infect. Dis. pmid:29343220
Crooks MG et al. How does azithromycin improve asthma exacerbations? 2018 Lancet pmid:29323653
Gibson PG How does azithromycin improve asthma exacerbations? - Author's reply. 2018 Lancet pmid:29323652
Tilahun Z and Fenta TG Coverage of azithromycin mass treatment for trachoma elimination in Northwestern Ethiopia: a community based cross-sectional study. 2018 BMC Ophthalmol pmid:30081851
Lundin MS et al. Lemierre's syndrome and 2016 American College of Physician guidelines for pharyngitis: no to empiric coverage for bacterial pharyngitis. While no role for routine Fusobacterium PCR, keep suspicion for this pathogen. 2018 BMJ Case Rep pmid:30030249
Celma A et al. Development of a Retention Time Interpolation scale (RTi) for liquid chromatography coupled to mass spectrometry in both positive and negative ionization modes. 2018 J Chromatogr A pmid:30005941
Lederhandler MH et al. Severe Oral Mucositis: A Rare Adverse Event of Pembrolizumab. 2018 J Drugs Dermatol pmid:30005106
Valor C and Huber K Atypical presentation of cat scratch disease: Parinaud's oculoglandular syndrome with facial nerve paresis. 2018 BMJ Case Rep pmid:29982178