Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Vaginosis, Bacterial D016585 10 associated lipids
Amebiasis D000562 2 associated lipids
Lung Diseases, Parasitic D008174 2 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Tooth Mobility D014086 2 associated lipids
Mitral Valve Stenosis D008946 3 associated lipids
Prostatitis D011472 5 associated lipids
Meningoencephalitis D008590 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Yazdanbakhsh AR et al. Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. 2016 Water Environ. Res. pmid:28661328
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Serdar Kutuk M et al. Relationship between maternal c-reactive protein level and neonatal outcome in patients with preterm premature rupture of membranes treated with Ampicillin and Azithromycin. 2016 J Obstet Gynaecol pmid:27825282
Ervin AM et al. Surveillance and Azithromycin Treatment for Newcomers and Travelers Evaluation (ASANTE) Trial: Design and Baseline Characteristics. 2016 Ophthalmic Epidemiol pmid:27820670
Weintraub A et al. In-vitro activity of solithromycin against anaerobic bacteria from the normal intestinal microbiota. 2016 Anaerobe pmid:27725229
Berkowitz ST et al. Resolution of spontaneous hemoabdomen secondary to peliosis hepatis following surgery and azithromycin treatment in a Bartonella species infected dog. 2016 J Vet Emerg Crit Care (San Antonio) pmid:27074964
Martín JM et al. Azithromycin for the Treatment of Ciclosporin-Induced Gingival Hyperplasia. 2016 Actas Dermosifiliogr pmid:26996332
Molini BJ et al. Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains. 2016 Sex Transm Dis pmid:27513385
Xiridou M et al. Cost-Effectiveness of Dual Antimicrobial Therapy for Gonococcal Infections Among Men Who Have Sex With Men in the Netherlands. 2016 Sex Transm Dis pmid:27513379
Mitjà O et al. Mass Treatment with Single-Dose Azithromycin for Yaws. 2016 N. Engl. J. Med. pmid:27626525
Cheng GS et al. Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant. 2016 Ann Am Thorac Soc pmid:27513368
Kobuchi S et al. Transport of Azithromycin into Extravascular Space in Rats. 2016 Antimicrob. Agents Chemother. pmid:27600045
Marks M et al. Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma. 2016 PLoS Negl Trop Dis pmid:27551787
Samson C et al. Long-term effects of azithromycin in patients with cystic fibrosis. 2016 Respir Med pmid:27492507
Akram FE et al. A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). 2016 Ann. Clin. Microbiol. Antimicrob. pmid:27530257
O'Farrell N Control of gonorrhoea and chlamydia in the UK. 2016 Lancet pmid:27477165
Zhu XH et al. Viral and Bacterial Etiology of Acute Diarrhea among Children under 5 Years of Age in Wuhan, China. 2016 Chin. Med. J. pmid:27503019
Dukers-Muijrers NH et al. Design of the FemCure study: prospective multicentre study on the transmission of genital and extra-genital Chlamydia trachomatis infections in women receiving routine care. 2016 BMC Infect. Dis. pmid:27502928
Haas AN et al. Predictors of clinical outcomes after periodontal treatment of aggressive periodontitis: 12-month randomized trial. 2016 Braz Oral Res pmid:27223128
Itaqui SR et al. In Vitro Synergism between Azithromycin or Terbinafine and Topical Antimicrobial Agents against Pythium insidiosum. 2016 Antimicrob. Agents Chemother. pmid:27216049
Wang Z and Meenach SA Synthesis and Characterization of Nanocomposite Microparticles (nCmP) for the Treatment of Cystic Fibrosis-Related Infections. 2016 Pharm. Res. pmid:27091030
Phong NC et al. In Vivo Efficacy and Tolerability of Artesunate-Azithromycin for the Treatment of Falciparum Malaria in Vietnam. 2016 Am. J. Trop. Med. Hyg. pmid:27215294
Ab Rahman N et al. Antibiotic prescribing in public and private practice: a cross-sectional study in primary care clinics in Malaysia. 2016 BMC Infect. Dis. pmid:27188538
Brown J et al. Shigellosis: high rates of antibiotic resistance necessitate new treatment recommendations. 2016 Med. J. Aust. pmid:27078594
Ramaiah B et al. High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice. 2016 Daru pmid:27150818
Rajabi O et al. Topical liposomal azithromycin in the treatment of acute cutaneous leishmaniasis. 2016 Dermatol Ther pmid:27073044
Geisler WM et al. Azithromycin versus Doxycycline for Chlamydia. 2016 N. Engl. J. Med. pmid:27144856
Dunn AL et al. Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl. 2016 Lab Med pmid:26984830
Kadota T et al. Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease. 2016 BMC Infect. Dis. pmid:26818764
Wladis EJ et al. Oral Antibiotics for Meibomian Gland-Related Ocular Surface Disease: A Report by the American Academy of Ophthalmology. 2016 Ophthalmology pmid:26707417
Deshpande D et al. Azithromycin Dose To Maximize Efficacy and Suppress Acquired Drug Resistance in Pulmonary Mycobacterium avium Disease. 2016 Antimicrob. Agents Chemother. pmid:26810646
Stokholm J et al. Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial. 2016 Lancet Respir Med pmid:26704020
Swatton JE et al. Impact of Azithromycin on the Quorum Sensing-Controlled Proteome of Pseudomonas aeruginosa. 2016 PLoS ONE pmid:26808156
Afshar M et al. Azithromycin use and outcomes in severe sepsis patients with and without pneumonia. 2016 J Crit Care pmid:26803186
Lenehan PJ et al. An evaluation strategy for potential QTc prolongation with chronic azithromycin therapy in cystic fibrosis. 2016 J. Cyst. Fibros. pmid:26698953
Lee H et al. New treatment options for infections caused by increasingly antimicrobial-resistant Neisseria gonorrhoeae. 2016 Expert Rev Anti Infect Ther pmid:26690658
Nakajima T et al. Microbiological and Clinical Effects of Sitafloxacin and Azithromycin in Periodontitis Patients Receiving Supportive Periodontal Therapy. 2016 Antimicrob. Agents Chemother. pmid:26729495
Jentsch HF et al. Nonsurgical therapy of chronic periodontitis with adjunctive systemic azithromycin or amoxicillin/metronidazole. 2016 Clin Oral Investig pmid:26685849
Slade J et al. Chlamydial Pre-Infection Protects from Subsequent Herpes Simplex Virus-2 Challenge in a Murine Vaginal Super-Infection Model. 2016 PLoS ONE pmid:26726882
Lococo F et al. Hemoptysis and Progressive Dyspnea in a 67-Year-Old Woman with History of Renal Transplantation. 2016 Am. J. Respir. Crit. Care Med. pmid:26681504
Al-Hity A and Lockington D Oral azithromycin as the systemic treatment of choice in the treatment of meibomian gland disease. 2016 Clin. Experiment. Ophthalmol. pmid:26441357
Wu TS et al. Postcesarean section wound infection caused by Mycobacterium massiliense. 2016 J Microbiol Immunol Infect pmid:26350122
Unger HW et al. Azithromycin-containing intermittent preventive treatment in pregnancy affects gestational weight gain, an important predictor of birthweight in Papua New Guinea - an exploratory analysis. 2016 Matern Child Nutr pmid:26373537
Nappe TM et al. Stevens-Johnson syndrome after treatment with azithromycin: an uncommon culprit. 2016 Am J Emerg Med pmid:26194400
Derad I et al. Hypertension and mild chronic kidney disease persist following severe haemolytic uraemic syndrome caused by Shiga toxin-producing Escherichia coli O104:H4 in adults. 2016 Nephrol. Dial. Transplant. pmid:26180049
Steeples LR et al. Real-time PCR using the 529 bp repeat element for the diagnosis of atypical ocular toxoplasmosis. 2016 Br J Ophthalmol pmid:26174811
Arora N et al. Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster. 2016 Nat Microbiol pmid:27918528
Retallack H et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. 2016 Proc. Natl. Acad. Sci. U.S.A. pmid:27911847
Brittain C et al. Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial. 2016 Trials pmid:27881151
Shimizu T and Suzaki H Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. 2016 Auris Nasus Larynx pmid:26441370