Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

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Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Parasitemia D018512 5 associated lipids
Abdominal Abscess D018784 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Pseudolymphoma D019310 1 associated lipids
Pouchitis D019449 3 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Mucositis D052016 7 associated lipids
Tendinopathy D052256 3 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Agarwal P et al. susceptibility of Indian isolates to different antimalarial drugs & antibiotics. 2017 Indian J. Med. Res. pmid:29512604
Yang Z et al. Azithromycin Causes a Novel Proarrhythmic Syndrome. 2017 Circ Arrhythm Electrophysiol pmid:28408648
Doan T et al. Gut Microbial Diversity in Antibiotic-Naive Children After Systemic Antibiotic Exposure: A Randomized Controlled Trial. 2017 Clin. Infect. Dis. pmid:28402408
Riddle MS et al. Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. 2017 Clin. Infect. Dis. pmid:29029033
Alchakaki A et al. Which patients with respiratory disease need long-term azithromycin? 2017 Cleve Clin J Med pmid:28985171
Li Y et al. Synergistic Activity of Berberine with Azithromycin against Pseudomonas Aeruginosa Isolated from Patients with Cystic Fibrosis of Lung In Vitro and In Vivo. 2017 Cell. Physiol. Biochem. pmid:28738346
Llop CJ et al. Antibiotic treatment patterns, costs, and resource utilization among patients with community acquired pneumonia: a US cohort study. 2017 Hosp Pract (1995) pmid:28064542
West SK et al. Treating village newcomers and travelers for trachoma: Results from ASANTE cluster randomized trial. 2017 PLoS ONE pmid:28662043
Johnson SR et al. Use of whole-genome sequencing data to analyze 23S rRNA-mediated azithromycin resistance. 2017 Int. J. Antimicrob. Agents pmid:28038960
Sanders AM et al. Burden of trachoma in five counties of Eastern Equatoria state, South Sudan: Results from population-based surveys. 2017 PLoS Negl Trop Dis pmid:28614375
Allen G Evidence appraisal of Tita ATN, Szychowski JM, Boggess K, et al. Adjunctive azithromycin prophylaxis for cesarean delivery.: N Engl J Med. 2016;375:1231-1241. 2017 AORN J pmid:28034388
Gensel JC et al. Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment. 2017 Sci Rep pmid:28057928
Sutton SS Is cardiovascular risk a concern when prescribing azithromycin? 2017 JAAPA pmid:28033168
Kawamura K et al. Azithromycin for idiopathic acute exacerbation of idiopathic pulmonary fibrosis: a retrospective single-center study. 2017 BMC Pulm Med pmid:28629448
Nozawa H et al. Pertussis without apparent cough in a disabled girl with a tracheostomy. 2017 J. Infect. Chemother. pmid:28623110
Manesh A et al. A case of clinical and microbiological failure of azithromycin therapy in Salmonella enterica serotype Typhi despite low azithromycin MIC. 2017 Int. J. Infect. Dis. pmid:27894983
Menzel M et al. Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. 2017 Oncotarget pmid:28415826
Kneidinger N et al. Lung volumes predict survival in patients with chronic lung allograft dysfunction. 2017 Eur. Respir. J. pmid:28404648
Fohner AE et al. PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. 2017 Pharmacogenet. Genomics pmid:28146011
Fuji S Azithromycin and Survival After Hematopoietic Stem Cell Transplant. 2017 JAMA pmid:29279920