Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Cat Diseases D002371 12 associated lipids
Stomatitis D013280 14 associated lipids
Weight Loss D015431 56 associated lipids
Tendinopathy D052256 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Opportunistic Infections D009894 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Authors Title Published Journal PubMed Link
Howard KB et al. Azithromycin versus erythromycin for community-acquired pneumonia: a cost-minimization analysis. 1999 Am J Health Syst Pharm pmid:10478989
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Hook EW et al. Azithromycin compared with penicillin G benzathine for treatment of incubating syphilis. 1999 Ann. Intern. Med. pmid:10498560
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Tan HH and Chan RK An open label comparative study of azithromycin and doxycycline in the treatment of non-gonococcal urethritis in males and Chlamydia trachomatis cervicitis in female sex workers in an STD clinic in Singapore. 1999 Singapore Med J pmid:10572491
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Sendi PP et al. Cost-effectiveness of azithromycin for preventing Mycobacterium avium complex infection in HIV-positive patients in the era of highly active antiretroviral therapy. The Swiss HIV Cohort Study. 1999 J. Antimicrob. Chemother. pmid:10590283
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Girgis NI et al. Azithromycin versus ciprofloxacin for treatment of uncomplicated typhoid fever in a randomized trial in Egypt that included patients with multidrug resistance. 1999 Antimicrob. Agents Chemother. pmid:10348767
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Credito KL et al. Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. 1999 Antimicrob. Agents Chemother. pmid:10428930
Giacometti A et al. Efficacy of treatment with paromomycin, azithromycin, and nitazoxanide in a patient with disseminated cryptosporidiosis. 1999 Eur. J. Clin. Microbiol. Infect. Dis. pmid:10691200
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Breitschwerdt EB et al. Efficacy of doxycycline, azithromycin, or trovafloxacin for treatment of experimental Rocky Mountain spotted fever in dogs. 1999 Antimicrob. Agents Chemother. pmid:10103185
Petitta A et al. Economic evaluation of three methods of treating urogenital chlamydial infections in the emergency department. 1999 Pharmacotherapy pmid:10331829
Cammarota G et al. Three-day antibiotic therapy with azithromycin and tinidazole plus lansoprazole or pantoprazole to cure Helicobacter pylori infection: a pilot study. 1999 Eur J Gastroenterol Hepatol pmid:10333196
Wirnsberger GH and Pfragner R Comment on "Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients" by Nash and Zaltzman. 1999 Transplantation pmid:10342326
Foster DR and Milan NL Potential interaction between azithromycin and warfarin. 1999 Pharmacotherapy pmid:10417043
Scaglione F et al. Interpretation of middle ear fluid concentrations of antibiotics: comparison between ceftibuten, cefixime and azithromycin. 1999 Br J Clin Pharmacol pmid:10215750
Khan AA et al. Effect of clarithromycin and azithromycin on production of cytokines by human monocytes. 1999 Int. J. Antimicrob. Agents pmid:10221415
Taylor KI and Taylor HR Distribution of azithromycin for the treatment of trachoma. 1999 Br J Ophthalmol pmid:10396186
Vcev A et al. High dose omeprazole plus amoxicillin and azithromycin in eradication of Helicobacter pylori in duodenal ulcers. 1999 Helicobacter pmid:10352088
Moore PA Dental therapeutic indications for the newer long-acting macrolide antibiotics. 1999 J Am Dent Assoc pmid:10492541
Ogasawara KK and Goodwin TM Efficacy of azithromycin in reducing lower genital Ureaplasma urealyticum colonization in women at risk for preterm delivery. 1999 Jan-Feb J Matern Fetal Med pmid:10052839
Klapan I et al. Azithromycin versus amoxicillin/clavulanate in the treatment of acute sinusitis. 1999 Jan-Feb Am J Otolaryngol pmid:9950107
Gorenek L et al. The diagnosis and treatment of Clostridium difficile in antibiotic-associated diarrhea. 1999 Jan-Feb Hepatogastroenterology pmid:10228818
Braz LM et al. [The evaluation of the efficacy of azithromycin and pyrimethamine used alone or in combination in the treatment of an experimental infection in mice by Toxoplasma gondii]. 1999 Jul-Aug Rev. Soc. Bras. Med. Trop. pmid:10495670
Sawhney N MAC prophylaxis in the era of polypharmacy. 1999 May-Jun WMJ pmid:10414219
Schönwald S et al. Azithromycin: single 1.5 g dose in the treatment of patients with atypical pneumonia syndrome--a randomized study. 1999 May-Jun Infection pmid:10378132
Paavonen J and Eggert-Kruse W Chlamydia trachomatis: impact on human reproduction. 1999 Sep-Oct Hum. Reprod. Update pmid:10582782
McNabb J et al. Comparison of azithromycin leukocyte disposition in healthy volunteers and volunteers with AIDS. 2000 Int. J. Antimicrob. Agents pmid:11185411
Amsden GW et al. A study of the pharmacokinetics of azithromycin and nelfinavir when coadministered in healthy volunteers. 2000 J Clin Pharmacol pmid:11185676
Garasiuta EG [Surgical treatment of ulnar and pre-patellar bursitis under ambulatory conditions]. 2000 Voen Med Zh pmid:12886538
Schissel DJ et al. Azithromycin eruption in infectious mononucleosis: a proposed mechanism of interaction. 2000 Cutis pmid:10738636
Giacometti A et al. Activity of nitazoxanide alone and in combination with azithromycin and rifabutin against Cryptosporidium parvum in cell culture. 2000 J. Antimicrob. Chemother. pmid:10747821
Bujanda L et al. Ranitidine bismuth citrate plus azithromycin for Helicobacter pylori eradication. 2000 J. Clin. Gastroenterol. pmid:10777206
Ress BD and Gross EM Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. 2000 Ann. Otol. Rhinol. Laryngol. pmid:10778901
Miller SA et al. Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human vascular smooth muscle and induces cellular proliferation. 2000 J. Surg. Res. pmid:10781378
Skerk V et al. Comparative analysis of azithromycin and doxycycline efficacy in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum. 2000 J Chemother pmid:10789560
Sasaki TY and Sumida KN Angioimmunoblastic T-cell lymphoma (AIL-TCL) following macrolide administration. 2000 Hawaii Med J pmid:10800250
Somani J et al. Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure. 2000 J. Infect. Dis. pmid:10762573
El-Sadr WM et al. Discontinuation of prophylaxis for Mycobacterium avium complex disease in HIV-infected patients who have a response to antiretroviral therapy. Terry Beirn Community Programs for Clinical Research on AIDS. 2000 N. Engl. J. Med. pmid:10766581
Brieland JK et al. Efficacy of SCH27899 in an animal model of Legionnaires' disease using immunocompromised A/J mice. 2000 Antimicrob. Agents Chemother. pmid:10770771
Laming AC et al. A targeted, single-dose azithromycin strategy for trachoma. 2000 Med. J. Aust. pmid:10772587
Turcinov D et al. Failure of azithromycin in treatment of Brill-Zinsser disease. 2000 Antimicrob. Agents Chemother. pmid:10817744
Tsitsika A et al. Single-oral-dose azithromycin prophylaxis against experimental streptococcal or staphylococcal aortic valve endocarditis. 2000 Antimicrob. Agents Chemother. pmid:10817749
Waterer GW et al. Fatal pneumococcal pneumonia attributed to macrolide resistance and azithromycin monotherapy. 2000 Chest pmid:11115489
Esposito S and Ascione T Short-course treatment for acute tonsillopharyngitis. 2000 Int. J. Antimicrob. Agents pmid:11118866
Gandhi R et al. Validated LC method for in-vitro analysis of azithromycin using electrochemical detection. 2000 J Pharm Biomed Anal pmid:11095310
Bowman RJ et al. Operational comparison of single-dose azithromycin and topical tetracycline for trachoma. 2000 Invest. Ophthalmol. Vis. Sci. pmid:11095598
Calabrese C et al. Pantoprazole, azithromycin and tinidazole: short duration triple therapy for eradication of Helicobacter pylori infection. 2000 Aliment. Pharmacol. Ther. pmid:11121909
DeAbate CA et al. The safety and efficacy of short course (5-day) moxifloxacin vs. azithromycin in the treatment of patients with acute exacerbation of chronic bronchitis. 2000 Respir Med pmid:11127487
Macaigne G et al. [Acute pseudoangiocholitic hepatitis probably induced by azithromycin]. 2000 Gastroenterol. Clin. Biol. pmid:11084438
Alvarez MP et al. [Pharmacovigilance study of azithromycin tablets (500 mg) in the treatment of adult patients with respiratory tract infections]. 2000 Rev Esp Quimioter pmid:11086281
Nagai K et al. In vitro development of resistance to ceftriaxone, cefprozil and azithromycin in Streptococcus pneumoniae. 2000 J. Antimicrob. Chemother. pmid:11102409
Sader H and Del'Alamo L Etest compared to broth microdilution: discrepant results when testing macrolides against Streptococcus pneumoniae indicate a need for better clinical and serum level/MIC correlation. 2000 Braz J Infect Dis pmid:11063559
Putnam SD et al. Pharyngeal colonization prevalence rates for Streptococcus pyogenes and Streptococcus pneumoniae in a respiratory chemoprophylaxis intervention study using azithromycin. 2000 Clin. Microbiol. Infect. pmid:11168029
Schilling F and Wagner AD [Azithromycin: an anti-inflammatory effect in chronic recurrent multifocal osteomyelitis? A preliminary report]. 2000 Z Rheumatol pmid:11142932
Powers JL et al. Comparison of the palatability of the oral suspension of cefdinir vs. amoxicillin/clavulanate potassium, cefprozil and azithromycin in pediatric patients. 2000 Pediatr. Infect. Dis. J. pmid:11144401
Duran JM and Amsden GW Azithromycin: indications for the future? 2000 Expert Opin Pharmacother pmid:11249533
McBroom JW Medical management of interstitial pregnancy with a retained IUD. A case report. 2000 J Reprod Med pmid:10900583
Koch CC et al. Apoptosis, oxidative metabolism and interleukin-8 production in human neutrophils exposed to azithromycin: effects of Streptococcus pneumoniae. 2000 J. Antimicrob. Chemother. pmid:10882684
Herrera D et al. The periodontal abscess (II). Short-term clinical and microbiological efficacy of 2 systemic antibiotic regimes. 2000 J. Clin. Periodontol. pmid:10883868
Anderson JL and Muhlestein JB The ACADEMIC study in perspective (Azithromycin in coronary artery disease: elimination of myocardial infection with Chlamydia). 2000 J. Infect. Dis. pmid:10839761
Dunne MW Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trial. 2000 J. Infect. Dis. pmid:10839762
Jackson LA Description and status of the azithromycin and coronary events study (ACES). 2000 J. Infect. Dis. pmid:10839763
Raja Babu KK et al. Confluent and reticulate papillomatosis: successful treatment with azithromycin. 2000 Br. J. Dermatol. pmid:10848767
SendaÄŸ F et al. Single dose oral azithromycin versus seven day doxycycline in the treatment of non-gonococcal mucopurulent endocervicitis. 2000 Aust N Z J Obstet Gynaecol pmid:10870778
Gruber F et al. Treatment of early syphilis with azithromycin. 2000 J Chemother pmid:10877520
Tateda K et al. Potential of macrolide antibiotics to inhibit protein synthesis of Pseudomonas aeruginosa: suppression of virulence factors and stress response. 2000 J. Infect. Chemother. pmid:11810524
Ernst EJ et al. Comparison of the serum and intracellular pharmacokinetics of azithromycin in healthy and diabetic volunteers. 2000 Pharmacotherapy pmid:10853621
Criqui GI et al. Effects of azithromycin on ozone-induced airway neutrophilia and cytokine release. 2000 Eur. Respir. J. pmid:10853849
Chinh NT et al. A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. 2000 Antimicrob. Agents Chemother. pmid:10858343
González de Aledo Linos A and García Merino J [Control of a school outbreak of serogroup B meningococcal disease by chemoprophylaxis with azithromycin and ciprofloxacin]. 2000 An. Esp. Pediatr. pmid:11521657
Oksi J [Diagnostics and treatment of Lyme borreliosis]. 2000 Duodecim pmid:11787113
Miyazaki S and Yamaguchi K [In vitro and in vivo antibacterial activities of azithromycin]. 2000 Jpn J Antibiot pmid:12572087
Shiba K [Pharmacokinetics and tissue distribution of azithromycin in humans]. 2000 Jpn J Antibiot pmid:12572088
Enogaki K [Transport to an infected site of azithromycin by phagocyte cells]. 2000 Jpn J Antibiot pmid:12572089
Oizumi K [Clinical evaluation of azithromycin for respiratory infectious diseases]. 2000 Jpn J Antibiot pmid:12572090
Nakayama I [Clinical studies of azithromycin, a new macrolide antibiotic, for infections in the field of surgery]. 2000 Jpn J Antibiot pmid:12572091
Sunakawa K [Summary of the clinical studies with azithromycin in the pediatric fields]. 2000 Jpn J Antibiot pmid:12572092
Naoya M [The clinical study of azithromycin in otolaryngologic infection]. 2000 Jpn J Antibiot pmid:12572093
Arata J [Azithromycin in the field of dermatology]. 2000 Jpn J Antibiot pmid:12572094
Sasaki J [Azithromycin in dentistry and oral surgery]. 2000 Jpn J Antibiot pmid:12572095
Grayston JT Secondary prevention antibiotic treatment trials for coronary artery disease. 2000 Circulation pmid:11023925
Muhlestein JB et al. Randomized secondary prevention trial of azithromycin in patients with coronary artery disease: primary clinical results of the ACADEMIC study. 2000 Circulation pmid:11023928
Bharat V and Mohanty B Bleeding complication during coumarin therapy due to amiodarone and azithromycin. 2000 J Assoc Physicians India pmid:11273517
Gulati R et al. Comparative bioavailability of two formulations of azithromycin. 2000 J Assoc Physicians India pmid:11273540