Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Pyomyositis D052880 2 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Acute Lung Injury D055371 33 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Neglected Diseases D058069 3 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Trichiasis D058457 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Tick Bites D064927 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Wynn RF et al. Azithromycin for cerebral toxoplasmosis in AIDS. 1993 Lancet pmid:8093526
Bailey RL et al. Randomised controlled trial of single-dose azithromycin in treatment of trachoma. 1993 Lancet pmid:8102427
Nahata MC et al. Pharmacokinetics of azithromycin in pediatric patients after oral administration of multiple doses of suspension. 1993 Antimicrob. Agents Chemother. pmid:8383944
Vaara M Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. 1993 Antimicrob. Agents Chemother. pmid:8383945
Brown ST et al. Azithromycin, rifabutin, and rifapentine for treatment and prophylaxis of Mycobacterium avium complex in rats treated with cyclosporine. 1993 Antimicrob. Agents Chemother. pmid:8384809
Cameron DJ Effectiveness of early Lyme disease treatment. 1993 Am. J. Med. pmid:8388627
Melski JW et al. Primary and secondary erythema migrans in central Wisconsin. 1993 Arch Dermatol pmid:8389536
Bonnet M and Van der Auwera P Preincubation of Haemophilus influenzae with subinhibitory concentrations of macrolides: influence on human neutrophil chemiluminescence. 1993 Antimicrob. Agents Chemother. pmid:8390808
Gordillo ME et al. In vitro activity of azithromycin against bacterial enteric pathogens. 1993 Antimicrob. Agents Chemother. pmid:8390813
Amacher DE et al. Preclinical toxicology studies with azithromycin: genetic toxicology evaluation. 1993 Mutat. Res. pmid:7685497
Agacfidan A et al. In vitro activity of azithromycin (CP-62,993) against Chlamydia trachomatis and Chlamydia pneumoniae. 1993 Antimicrob. Agents Chemother. pmid:8239579
Tomazic J et al. In vivo administration of azithromycin affects lymphocyte activity in vitro. 1993 Antimicrob. Agents Chemother. pmid:8239585
Cantin L and Chamberland S In vitro evaluation of the activities of azithromycin alone and combined with pyrimethamine against Toxoplasma gondii. 1993 Antimicrob. Agents Chemother. pmid:8239619
Gage TW New drugs from 1991-1992. 1993 Tex Dent J pmid:8273018
Holdcroft C Two new macrolide antibiotics: clarithromycin and azithromycin. 1993 Nurse Pract pmid:8380492
Spangler SK and Appelbaum PC Oxyrase, a method which avoids CO2 in the incubation atmosphere for anaerobic susceptibility testing of antibiotics affected by CO2. 1993 J. Clin. Microbiol. pmid:8381817
de Górgolas Hernández-Mora M et al. [Therapeutic approaches to cryptosporidiosis. A review of the literature]. 1993 Rev Clin Esp pmid:8259458
Berger BW Lyme disease. 1993 Semin Dermatol pmid:8312152
Gingras BA and Jensen JB Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. 1993 Am. J. Trop. Med. Hyg. pmid:8394660
Mansoor GA et al. Azithromycin-induced acute interstitial nephritis. 1993 Ann. Intern. Med. pmid:8395778