Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Amebiasis D000562 2 associated lipids
Anaphylaxis D000707 35 associated lipids
Anaplasmataceae Infections D000711 3 associated lipids
Angina, Unstable D000789 14 associated lipids
Aphasia, Broca D001039 1 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Bacterial Infections D001424 21 associated lipids
Bartonella Infections D001474 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Verdon MS et al. Pilot study of azithromycin for treatment of primary and secondary syphilis. 1994 Clin. Infect. Dis. pmid:7811868
Beale AS and Upshon PA Characteristics of murine model of genital infection with Chlamydia trachomatis and effects of therapy with tetracyclines, amoxicillin-clavulanic acid, or azithromycin. 1994 Antimicrob. Agents Chemother. pmid:7811001
Rakita RM et al. Intracellular activity of azithromycin against bacterial enteric pathogens. 1994 Antimicrob. Agents Chemother. pmid:7810998
Weber JT and Johnson RE New treatments for Chlamydia trachomatis genital infection. 1995 Clin. Infect. Dis. pmid:7795110
Schlossberg D Azithromycin and clarithromycin. 1995 Med. Clin. North Am. pmid:7791424
Rizzato G et al. Efficacy of a three day course of azithromycin in moderately severe community-acquired pneumonia. 1995 Eur. Respir. J. pmid:7789484
Nilsen OG Pharmacokinetics of macrolides. Comparison of plasma, tissue and free concentrations with special reference to roxithromycin. 1995 Infection pmid:7782117
Pascual A et al. Factors affecting the intracellular accumulation and activity of azithromycin. 1995 J. Antimicrob. Chemother. pmid:7768786
Ives DV et al. Impact of clarithromycin and azithromycin on patterns of treatment and survival among AIDS patients with disseminated Mycobacterium avium complex. 1995 AIDS pmid:7755914
Hunter RP et al. Pharmacokinetics, oral bioavailability and tissue distribution of azithromycin in cats. 1995 J. Vet. Pharmacol. Ther. pmid:7752305
Ramadan MA et al. Post-antibiotic effect of azithromycin and erythromycin on streptococcal susceptibility to phagocytosis. 1995 J. Med. Microbiol. pmid:7752216
Schönwald S et al. Three-day azithromycin compared with ten-day roxithromycin treatment of atypical pneumonia. 1994 Scand. J. Infect. Dis. pmid:7747094
Tuffrey M et al. The effect of a single oral dose of azithromycin on chlamydial infertility and oviduct ultrastructure in mice. 1994 J. Antimicrob. Chemother. pmid:7730241
Adal KA et al. Photo quiz. Bacillary angiomatosis. 1995 Clin. Infect. Dis. pmid:7727641
O'Day DM et al. Ocular pharmacokinetics of orally administered azithromycin in rabbits. 1994 J Ocul Pharmacol pmid:7714407
Nuovo J et al. Cost-effectiveness analysis of five different antibiotic regimens for the treatment of uncomplicated Chlamydia trachomatis cervicitis. 1995 Jan-Feb J Am Board Fam Pract pmid:7701965
Sher AA et al. [Interactions in the system of copper ion-azalide (azithromycin)]. 1994 Sep-Oct Antibiot. Khimioter. pmid:7695446
Malinverni R et al. Effects of two antibiotic regimens on course and persistence of experimental Chlamydia pneumoniae TWAR pneumonitis. 1995 Antimicrob. Agents Chemother. pmid:7695327
Odenholt-Tornqvist I et al. Postantibiotic effects and postantibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens. 1995 Antimicrob. Agents Chemother. pmid:7695310
Amacher DE et al. Preclinical toxicology studies with azithromycin: genetic toxicology evaluation. 1993 Mutat. Res. pmid:7685497
Beghi G et al. Efficacy and tolerability of azithromycin versus amoxicillin/clavulanic acid in acute purulent exacerbation of chronic bronchitis. 1995 J Chemother pmid:7666122
Hashisaki GT Update on macrolide antibiotics. 1995 May-Jun Am J Otolaryngol pmid:7661309
Onyeji CO et al. Activities of clarithromycin, azithromycin, and ofloxacin in combination with liposomal or unencapsulated granulocyte-macrophage colony-stimulating factor against intramacrophage Mycobacterium avium-Mycobacterium intracellulare. 1995 J. Infect. Dis. pmid:7658075
Debets-Ossenkopp YJ et al. Effect of an acidic environment on the susceptibility of Helicobacter pylori to trospectomycin and other antimicrobial agents. 1995 Eur. J. Clin. Microbiol. Infect. Dis. pmid:7649202
Yeo AE and Rieckmann KH Increased antimalarial activity of azithromycin during prolonged exposure of Plasmodium falciparum in vitro. 1995 Int. J. Parasitol. pmid:7635629
Bowden FJ et al. Azithromycin and syphilis. 1995 Genitourin Med pmid:7635501
Management of genital Chlamydia trachomatis infections. 1994 Drug Ther Bull pmid:7635012
Péc J et al. [Treatment of chlamydia infections and a brief review of the problems]. 1995 Bratisl Lek Listy pmid:7633932
Schmid GP and Fontanarosa PB Evolving strategies for management of the nongonococcal urethritis syndrome. 1995 JAMA pmid:7629989
Stamm WE et al. Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. 1995 JAMA pmid:7629982
Barry AL et al. Relative potencies of azithromycin, clarithromycin and five other orally administered antibiotics. 1995 J. Antimicrob. Chemother. pmid:7628991
Goldstein EJ et al. Comparative in vitro activities of azithromycin, Bay y 3118, levofloxacin, sparfloxacin, and 11 other oral antimicrobial agents against 194 aerobic and anaerobic bite wound isolates. 1995 Antimicrob. Agents Chemother. pmid:7625795
Fouda HG and Schneider RP Quantitative determination of the antibiotic azithromycin in human serum by high-performance liquid chromatography (HPLC)-atmospheric pressure chemical ionization mass spectrometry: correlation with a standard HPLC-electrochemical method. 1995 Ther Drug Monit pmid:7624907
Ljutić D and Rumboldt Z Possible interaction between azithromycin and cyclosporin: a case report. 1995 Nephron pmid:7617103
Kobayashi H et al. [Study on azithromycin in treatment of diffuse panbronchiolitis]. 1995 Kansenshogaku Zasshi pmid:7616016
Spangler SK et al. Susceptibilities of 201 anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin by oxyrase agar dilution and E test methodologies. 1995 J. Clin. Microbiol. pmid:7615756
Vartiovaara I Living with Lyme. 1995 Lancet pmid:7605437
Adegbola RA et al. Effect of azithromycin on pharyngeal microflora. 1995 Pediatr. Infect. Dis. J. pmid:7603826
Bamberger DM et al. Azithromycin in an experimental Staphylococcus aureus abscess model. 1995 J. Antimicrob. Chemother. pmid:7592175
Worm AM and Osterlind A Azithromycin levels in cervical mucus and plasma after a single 1.0g oral dose for chlamydial cervicitis. 1995 Genitourin Med pmid:7590717
Backman JT et al. Azithromycin does not increase plasma concentrations of oral midazolam. 1995 Int J Clin Pharmacol Ther pmid:7582388
Anderson SL et al. Prophylaxis of Plasmodium falciparum malaria with azithromycin administered to volunteers. 1995 Ann. Intern. Med. pmid:7574195
Wawer MJ et al. AIDS intervention in Uganda. 1995 Science pmid:7570005
Sadiq ST et al. Effects of azithromycin on malariometric indices in The Gambia. 1995 Lancet pmid:7564674
Van Asselt GJ et al. Susceptibility of Streptococcus pyogenes to azithromycin, clarithromycin, erythromycin and roxithromycin in vitro. 1995 J. Med. Microbiol. pmid:7563004
Carlier MB et al. Accumulation, release and subcellular localization of azithromycin in phagocytic and non-phagocytic cells in culture. 1994 Int J Tissue React pmid:7558665
Bokemeyer B [Combined therapy with azithromycin and omeprazole for the eradication of Helicobacter pylori]. 1995 Dtsch. Med. Wochenschr. pmid:7555645
Qadri SM et al. Antibacterial activity of azithromycin against Brucella melitensis. 1995 Jul-Aug Chemotherapy pmid:7555205
Harris S et al. Azithromycin and terfenadine: lack of drug interaction. 1995 Clin. Pharmacol. Ther. pmid:7554704
Genç M and Mårdh A A cost-effectiveness analysis of screening and treatment for Chlamydia trachomatis infection in asymptomatic women. 1996 Ann. Intern. Med. pmid:7503471