Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Acute Lung Injury D055371 33 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Pyomyositis D052880 2 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Tendinopathy D052256 3 associated lipids
Mucositis D052016 7 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Karhu E et al. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. 2017 J. Nat. Prod. pmid:29043803
Tuite AR et al. Impact of Rapid Susceptibility Testing and Antibiotic Selection Strategy on the Emergence and Spread of Antibiotic Resistance in Gonorrhea. 2017 J. Infect. Dis. pmid:28968710
Trembizki E et al. High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia. 2017 J. Med. Microbiol. pmid:28893363
Horner PJ and Martin DH Mycoplasma genitalium Infection in Men. 2017 J. Infect. Dis. pmid:28838074
Bystrzycka W et al. Azithromycin and Chloramphenicol Diminish Neutrophil Extracellular Traps (NETs) Release. 2017 Int J Mol Sci pmid:29292737
Pavlinac PB et al. Azithromycin to prevent post-discharge morbidity and mortality in Kenyan children: a protocol for a randomised, double-blind, placebo-controlled trial (the Toto Bora trial). 2017 BMJ Open pmid:29289941
Last AR et al. The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma-endemic island communities in West Africa. 2017 Parasit Vectors pmid:29282126
Husein-ElAhmed H Single nontender ulcer on the glans. 2017 J Fam Pract pmid:28375399
Leeyaphan C et al. Treatment Outcomes for Rectal Lymphogranuloma Venereum in Men Who Have Sex with Men Using Doxycycline, Azithromycin, or Both: A Review of Clinical Cases. 2017 Sex Transm Dis pmid:28282652
Ito S et al. Haemophilus influenzae Isolated From Men With Acute Urethritis: Its Pathogenic Roles, Responses to Antimicrobial Chemotherapies, and Antimicrobial Susceptibilities. 2017 Sex Transm Dis pmid:28282645
Stieler Stewart AL et al. Effects of clarithromycin, azithromycin and rifampicin on terbutaline-induced sweating in foals. 2017 Equine Vet. J. pmid:28238211
Allan RN et al. Cephalosporin-NO-donor prodrug PYRRO-C3D shows β-lactam-mediated activity against Streptococcus pneumoniae biofilms. 2017 Nitric Oxide pmid:28235635
Wiesenfeld HC Screening for Chlamydia trachomatis Infections in Women. 2017 N. Engl. J. Med. pmid:28225683
Shmarina G et al. Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression. 2017 Int. Arch. Allergy Immunol. pmid:28219060
Cluver C et al. Interventions for treating genital Chlamydia trachomatis infection in pregnancy. 2017 Cochrane Database Syst Rev pmid:28937705
Molefe NI et al. Oral administration of azithromycin ameliorates trypanosomosis in Trypanosoma congolense-infected mice. 2017 Parasitol. Res. pmid:28674747
Batteiger BE Azithromycin Efficacy in Asymptomatic Rectal Chlamydial Infection in Men Who Have Sex With Men: A More Definitive Answer Soon? 2017 Sex Transm Dis pmid:28604482
Sonavane AD and Rathi PM Fitz-Hugh-Curtis syndrome. 2017 Indian J. Med. Res. pmid:28574030
Ra SW et al. Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. 2017 Respir. Res. pmid:28558695
Karalius VP et al. Bordetella parapertussis outbreak in Southeastern Minnesota and the United States, 2014. 2017 Medicine (Baltimore) pmid:28514288
Read TR et al. Azithromycin 1.5g Over 5 Days Compared to 1g Single Dose in Urethral Mycoplasma genitalium: Impact on Treatment Outcome and Resistance. 2017 Clin. Infect. Dis. pmid:28011607
Vodstrcil LA et al. Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS). 2017 PLoS ONE pmid:28498845
Schwameis M et al. Topical azithromycin for the prevention of Lyme borreliosis: a randomised, placebo-controlled, phase 3 efficacy trial. 2017 Lancet Infect Dis pmid:28007428
Houinei W et al. Haemophilus ducreyi DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea. 2017 PLoS Negl Trop Dis pmid:28489855
Nenoff P et al. [Non-viral sexually transmitted infections - Epidemiology, clinical manifestations, diagnostics and therapy : Part 1: Gonococci]. 2017 Hautarzt pmid:27981386
Rutenberg D et al. Efficacy of Tulathromycin for the Treatment of Foals with Mild to Moderate Bronchopneumonia. 2017 J. Vet. Intern. Med. pmid:28421633
Trifirò G et al. Use of azithromycin and risk of ventricular arrhythmia. 2017 CMAJ pmid:28420680
Amza A et al. A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children. 2017 Clin. Infect. Dis. pmid:27956455
Papp JR et al. Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA. 2017 Emerging Infect. Dis. pmid:28418303
Liu Y et al. Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. 2017 Life Sci. pmid:27916734
Smith KS et al. Biological and Behavioral Factors Associated With Positive Chlamydia Retests. 2017 Sex Transm Dis pmid:28608791
Wind CM et al. Decreased Azithromycin Susceptibility of Neisseria gonorrhoeae Isolates in Patients Recently Treated with Azithromycin. 2017 Clin. Infect. Dis. pmid:28510723
van Wagensveld L et al. [Persistent, therapy-resistant conjunctivitis: consider infection with Chlamydia trachomatis]. 2017 Ned Tijdschr Geneeskd pmid:28443807
Foerster S et al. A new rapid resazurin-based microdilution assay for antimicrobial susceptibility testing of Neisseria gonorrhoeae. 2017 J. Antimicrob. Chemother. pmid:28431096
Murphy TK et al. A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder. 2017 J Child Adolesc Psychopharmacol pmid:28358599
Zhang Y et al. Novel Detection Strategy To Rapidly Evaluate the Efficacy of Antichlamydial Agents. 2017 Antimicrob. Agents Chemother. pmid:27855081
Waites KB et al. In Vitro Activities of Lefamulin and Other Antimicrobial Agents against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China. 2017 Antimicrob. Agents Chemother. pmid:27855075
Thompson DF and Ramos CL Antibiotic-Induced Rash in Patients With Infectious Mononucleosis. 2017 Ann Pharmacother pmid:27620494
Rajesh AM and Popat KM Taste masking of azithromycin by resin complex and sustained release through interpenetrating polymer network with functionalized biopolymers. 2017 Drug Dev Ind Pharm pmid:27600608
Romero L et al. Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. 2017 Cochrane Database Syst Rev pmid:29226307
Dror T et al. Microbiota manipulation for weight change. 2017 Microb. Pathog. pmid:26792677
Lusk MJ et al. Cervicitis: a prospective observational study of empiric azithromycin treatment in women with cervicitis and non-specific cervicitis. 2017 Int J STD AIDS pmid:26792283
Burr SE et al. Does azithromycin given to women in labour decrease ocular bacterial infection in neonates? A double-blind, randomized trial. 2017 BMC Infect. Dis. pmid:29282015
Wind CM et al. A Case-Control Study of Molecular Epidemiology in Relation to Azithromycin Resistance in Neisseria gonorrhoeae Isolates Collected in Amsterdam, the Netherlands, between 2008 and 2015. 2017 Antimicrob. Agents Chemother. pmid:28373191
Watson JR et al. Healthcare Claims Data: An Underutilized Tool for Pediatric Outpatient Antimicrobial Stewardship. 2017 Clin. Infect. Dis. pmid:28329388
Thompson CN et al. Treatment Response in Enteric Fever in an Era of Increasing Antimicrobial Resistance: An Individual Patient Data Analysis of 2092 Participants Enrolled into 4 Randomized, Controlled Trials in Nepal. 2017 Clin. Infect. Dis. pmid:28329181
Emerging risk of untreatable gonorrhea and what to do about it. 2017 Can Fam Physician pmid:28292798
Halhal B et al. Pertussis Outbreak Among Soldiers During Basic Training: The Need for Updated Protocols. 2017 Mil Med pmid:28291499
Çelik Payçu DG and Büyükbaba Boral Ö [Effects of azithromycin and Chlorella vulgaris treatment on certain cytokine values and NK cell activity in an acute murine toxoplasmosis model]. 2017 Mikrobiyol Bul pmid:28283010
Stanbrook MB Azithromycin reduced exacerbations and improved QoL in symptomatic asthma despite inhaled maintenance therapy. 2017 Ann. Intern. Med. pmid:29049761