Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Acute Lung Injury D055371 33 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Pyomyositis D052880 2 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Tendinopathy D052256 3 associated lipids
Mucositis D052016 7 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Li X et al. Preparation and characterization of azithromycin--Aerosil 200 solid dispersions with enhanced physical stability. 2015 Int J Pharm pmid:25794608
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Hildebrand F et al. Efficacy of gamithromycin for the treatment of foals with mild to moderate bronchopneumonia. 2015 J. Vet. Intern. Med. pmid:25619521
Wessels MR et al. Case records of the Massachusetts General Hospital. Case 6-2015. A 16-year-old boy with coughing spells. 2015 N. Engl. J. Med. pmid:25693017
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Khosropour CM et al. Efficacy of standard therapies against Ureaplasma species and persistence among men with non-gonococcal urethritis enrolled in a randomised controlled trial. 2015 Sex Transm Infect pmid:25616607
Liu Y et al. Can tetracycline antibiotics duplicate the ability of azithromycin to stimulate human meibomian gland epithelial cell differentiation? 2015 Cornea pmid:25611398
Chen M et al. Azithromycin attenuates cigarette smoke extract-induced oxidative stress injury in human alveolar epithelial cells. 2015 Mol Med Rep pmid:25607112
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Unger HW et al. Sulphadoxine-pyrimethamine plus azithromycin for the prevention of low birthweight in Papua New Guinea: a randomised controlled trial. 2015 BMC Med pmid:25591391
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Fraser LA et al. Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. 2015 Ann Pharmacother pmid:25429094
Solleti VS et al. Antimicrobial properties of liposomal azithromycin for Pseudomonas infections in cystic fibrosis patients. 2015 J. Antimicrob. Chemother. pmid:25416744
Chou HW et al. Risks of cardiac arrhythmia and mortality among patients using new-generation macrolides, fluoroquinolones, and β-lactam/β-lactamase inhibitors: a Taiwanese nationwide study. 2015 Clin. Infect. Dis. pmid:25409476
Bauquier JR et al. Anti-inflammatory effects of four potential anti-endotoxaemic drugs assessed in vitro using equine whole blood assays. 2015 J. Vet. Pharmacol. Ther. pmid:25407884
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Bissessor M et al. Persistence of Neisseria gonorrhoeae DNA following treatment for pharyngeal and rectal gonorrhea is influenced by antibiotic susceptibility and reinfection. 2015 Clin. Infect. Dis. pmid:25371490
Ohara H et al. Azithromycin Can Prolong QT Interval and Suppress Ventricular Contraction, but Will Not Induce Torsade de Pointes. 2015 Cardiovasc. Toxicol. pmid:25367413
Chi KH et al. Molecular differentiation of Treponema pallidum subspecies in skin ulceration clinically suspected as yaws in Vanuatu using real-time multiplex PCR and serological methods. 2015 Am. J. Trop. Med. Hyg. pmid:25404075
Merchan LM et al. Pharmacokinetics, microbial response, and pulmonary outcomes of multidose intravenous azithromycin in preterm infants at risk for Ureaplasma respiratory colonization. 2015 Antimicrob. Agents Chemother. pmid:25385115
Schögler A et al. Novel antiviral properties of azithromycin in cystic fibrosis airway epithelial cells. 2015 Eur. Respir. J. pmid:25359346
Nonaka L et al. Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. 2015 Lett. Appl. Microbiol. pmid:25765542
Dubois J et al. In vitro and intracellular activities of peptide deformylase inhibitor GSK1322322 against Legionella pneumophila isolates. 2015 Antimicrob. Agents Chemother. pmid:25348534
Li Y et al. Where macrolide resistance is prevalent. 2015 APMIS pmid:25703275
Kashkouli MB et al. Oral azithromycin versus doxycycline in meibomian gland dysfunction: a randomised double-masked open-label clinical trial. 2015 Br J Ophthalmol pmid:25138765
Gundevia Z et al. Positivity at test of cure following first-line treatment for genital Mycoplasma genitalium: follow-up of a clinical cohort. 2015 Sex Transm Infect pmid:25096921
Hussain S et al. N-acetylcysteine and azithromycin affect the innate immune response in cystic fibrosis bronchial epithelial cells in vitro. 2015 Exp. Lung Res. pmid:25058850
Sandrock CE and Norris A Infection in severe asthma exacerbations and critical asthma syndrome. 2015 Clin Rev Allergy Immunol pmid:24984968
Aucamp M et al. Amorphous azithromycin with improved aqueous solubility and intestinal membrane permeability. 2015 Drug Dev Ind Pharm pmid:24980913
Martinez MA et al. Clinical and histologic features of azithromycin-induced liver injury. 2015 Clin. Gastroenterol. Hepatol. pmid:25111234
Cabeza J et al. Feasibility of Chlamydia trachomatis screening and treatment in pregnant women in Lima, Peru: a prospective study in two large urban hospitals. 2015 Sex Transm Infect pmid:25107711
Ratjen F et al. Response to letter. 2015 Pediatr. Pulmonol. pmid:24700677
Tayob N and Murray S Nonparametric tests of treatment effect based on combined endpoints for mortality and recurrent events. 2015 Biostatistics pmid:24719282
Geisler WM et al. Azithromycin versus Doxycycline for Urogenital Chlamydia trachomatis Infection. 2015 N. Engl. J. Med. pmid:26699167
Smith C et al. Use and safety of azithromycin in neonates: a systematic review. 2015 BMJ Open pmid:26656010
Solomon AW et al. Trachoma and Yaws: Common Ground? 2015 PLoS Negl Trop Dis pmid:26633176
Ruíz del Olmo I et al. [Severe neutropenia as side effect of medical treatment in nontuberculous mycobacterial adenitis]. 2015 Rev Chilena Infectol pmid:26633119
Woodruff AE et al. Azithromycin-Induced, Biopsy-Proven Acute Interstitial Nephritis in an Adult Successfully Treated with Low-Dose Corticosteroids. 2015 Pharmacotherapy pmid:26598102
Jensen EA et al. Evidence-Based Pharmacologic Therapies for Prevention of Bronchopulmonary Dysplasia: Application of the Grading of Recommendations Assessment, Development, and Evaluation Methodology. 2015 Clin Perinatol pmid:26593077
Fan WG et al. Male Paraurethral Duct Infection and Subsequent Paraurethral Duct Dilation. 2015 Chin. Med. J. pmid:26608997
Wise J Early use of azithromycin may reduce severity of wheezing, study finds. 2015 BMJ pmid:26582751
Maračić S et al. 1,2,3-Triazole pharmacophore-based benzofused nitrogen/sulfur heterocycles with potential anti-Moraxella catarrhalis activity. 2015 Bioorg. Med. Chem. pmid:26578325
Zhang B et al. Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury. 2015 J Neuroinflammation pmid:26597676
Cohen RT and Pelton SI Individual Benefit vs Societal Effect of Antibiotic Prescribing for Preschool Children With Recurrent Wheeze. 2015 JAMA pmid:26575058
Roca A et al. Prevention of bacterial infections in the newborn by pre-delivery administration of azithromycin: Study protocol of a randomized efficacy trial. 2015 BMC Pregnancy Childbirth pmid:26585192
Bacharier LB et al. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. 2015 JAMA pmid:26575060
Hemmige V et al. Recurrent skin and soft tissue infections in HIV-infected patients during a 5-year period: incidence and risk factors in a retrospective cohort study. 2015 BMC Infect. Dis. pmid:26503616
Su XH et al. Multidrug-Resistant Neisseria gonorrhoeae Isolates from Nanjing, China, Are Sensitive to Killing by a Novel DNA Gyrase Inhibitor, ETX0914 (AZD0914). 2015 Antimicrob. Agents Chemother. pmid:26482313
Pollock E and Hasse B [CME. Pertussis]]. 2015 Praxis (Bern 1994) pmid:26331198
Xue J et al. Occurrence of high-level azithromycin-resistant Neisseria gonorrhoeae isolates in China. 2015 J. Antimicrob. Chemother. pmid:26316384
McCallum GB et al. Further clinical trials on macrolides for bronchiolitis in infants are unnecessary. 2015 J. Allergy Clin. Immunol. pmid:26316096
Pavlova A and Gumbart JC Parametrization of macrolide antibiotics using the force field toolkit. 2015 J Comput Chem pmid:26280362
Puri K et al. Bartonella Osteomyelitis of the Acetabulum: Case Report and Review of the Literature. 2015 Vector Borne Zoonotic Dis. pmid:26273806
Beigelman A and Bacharier LB Reply: To PMID 25458910. 2015 J. Allergy Clin. Immunol. pmid:26309182
Marks M et al. Impact of Community Mass Treatment with Azithromycin for Trachoma Elimination on the Prevalence of Yaws. 2015 PLoS Negl Trop Dis pmid:26241484
Stellari F et al. In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa and its modulation by azithromycin. 2015 J Transl Med pmid:26239109
Taylor SP et al. Azithromycin for the Prevention of COPD Exacerbations: The Good, Bad, and Ugly. 2015 Am. J. Med. pmid:26291905
Haruki Y et al. [Investigation of Intravenous Azithromycin Treatment Safety When Reducing Solvent for Intensive Care Unit Patients]. 2015 Yakugaku Zasshi pmid:26234357
Wetherbee EE et al. Self-reported alcohol intake and risk of acute exacerbations of chronic obstructive pulmonary disease: a prospective cohort study. 2015 Int J Chron Obstruct Pulmon Dis pmid:26229455
Moi H et al. Management of non-gonococcal urethritis. 2015 BMC Infect. Dis. pmid:26220178
Kong FY and Hocking JS Treatment challenges for urogenital and anorectal Chlamydia trachomatis. 2015 BMC Infect. Dis. pmid:26220080
Å majs D et al. Macrolide Resistance in the Syphilis Spirochete, Treponema pallidum ssp. pallidum: Can We Also Expect Macrolide-Resistant Yaws Strains? 2015 Am. J. Trop. Med. Hyg. pmid:26217043
Beigelman A et al. Does azithromycin modify viral load during severe respiratory syncytial virus bronchiolitis? 2015 J. Allergy Clin. Immunol. pmid:26215052
Pereira A et al. Acute onset of widespread pustular eruption. 2015 Aust Fam Physician pmid:26209988
Zhang L et al. Effects of azithromycin on gene expression profiles of proinflammatory and anti-inflammatory mediators in the eyelid margin and conjunctiva of patients with meibomian gland disease. 2015 JAMA Ophthalmol pmid:26204109
Wilson DW et al. Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum. 2015 BMC Biol. pmid:26187647
Furfaro LL et al. In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin. 2015 Int. J. Antimicrob. Agents pmid:26141231
Farber FR et al. Atraumatic splenic rupture from Babesia: A disease of the otherwise healthy patient. 2015 Ticks Tick Borne Dis pmid:26123434
Ahmed N et al. Donovanosis causing lymphadenitis, mastoiditis, and meningitis in a child. 2015 Lancet pmid:26122163
Jo KW et al. The efficacy of prophylactic azithromycin on bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation. 2015 Int. J. Hematol. pmid:26121954
Koepke R et al. Widespread Bordetella parapertussis Infections-Wisconsin, 2011-2012: Clinical and Epidemiologic Features and Antibiotic Use for Treatment and Prevention. 2015 Clin. Infect. Dis. pmid:26113655
Qin YH et al. Transdermal application of azithromycin-amlodipine-heparin gel enhances survival of infected random ischaemic flap. 2015 J Plast Surg Hand Surg pmid:26083309
Missov E and Cogswell R Sudden cardiac death, mitral valve prolapse, and long QT syndrome. 2015 Am. J. Med. pmid:26071830
Buset SL et al. Non-surgical periodontal therapy supplemented with systemically administered azithromycin: a systematic review of RCTs. 2015 Clin Oral Investig pmid:26063646
Hauser G et al. Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. 2015 Medicine (Baltimore) pmid:25929897
Yin SM et al. Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. 2015 J. Clin. Immunol. pmid:26048260
Craig AP et al. Is it time to switch to doxycycline from azithromycin for treating genital chlamydial infections in women? Modelling the impact of autoinoculation from the gastrointestinal tract to the genital tract. 2015 BMC Infect. Dis. pmid:25925662
Abely M et al. [National consensus regarding azithromycin use in cystic fibrosis]. 2015 Rev Mal Respir pmid:26003196
Cusini M Therapy for Gonococcal and Non-gonococcal Genital Infections is a Major Problem for Clinicians. 2015 Acta Derm. Venereol. pmid:25917593
Harding-Esch E et al. Costs of testing for ocular Chlamydia trachomatis infection compared to mass drug administration for trachoma in the Gambia: application of results from the PRET study. 2015 PLoS Negl Trop Dis pmid:25901349
Escalante MG et al. Comparison of Azithromycin and Amoxicillin Before Dental Implant Placement: An Exploratory Study of Bioavailability and Resolution of Postoperative Inflammation. 2015 J. Periodontol. pmid:26252749
Rudoler N et al. Comparison of the acute phase protein and antioxidant responses in dogs vaccinated against canine monocytic ehrlichiosis and naive-challenged dogs. 2015 Parasit Vectors pmid:25888870
Carter N and Horner P Treatment regimens in non-gonococcal urethritis. 2015 Sex Transm Infect pmid:25990780
Chandra R et al. Comparison of azithromycin plus chloroquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in children in Africa: a randomized, open-label study. 2015 Malar. J. pmid:25881046
Schroeck JL et al. Factors associated with antibiotic misuse in outpatient treatment for upper respiratory tract infections. 2015 Antimicrob. Agents Chemother. pmid:25870064
Verleden GM et al. Current views on chronic rejection after lung transplantation. 2015 Transpl. Int. pmid:25857869
Waites KB et al. In vitro antibacterial activity of AZD0914 against human Mycoplasmas and Ureaplasmas. 2015 Antimicrob. Agents Chemother. pmid:25824220
Unemo M et al. Five-day Azithromycin Treatment Regimen for Mycoplasma genitalium Infection Also Effectively Eradicates Chlamydia trachomatis. 2015 Acta Derm. Venereol. pmid:25823977
Nakamura M et al. Cat-scratch disease presenting as a solitary splenic abscess in an elderly man. 2015 BMJ Case Rep pmid:25804947
Phelan VV et al. Mass Spectrometry Analysis of Pseudomonas aeruginosa Treated with Azithromycin. 2015 J. Am. Soc. Mass Spectrom. pmid:25801585