Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gaydos CA | Mycoplasma genitalium: Accurate Diagnosis Is Necessary for Adequate Treatment. | 2017 | J. Infect. Dis. | pmid:28838072 |
| Ribeiro M et al. | Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells. | 2017 | Exp. Parasitol. | pmid:28803905 |
| Benn K et al. | Bradycardia and Hypothermia Complicating Azithromycin Treatment. | 2017 | Am J Case Rep | pmid:28798290 |
| Mei J et al. | Implications of intrapartum azithromycin on neonatal microbiota. | 2017 | Lancet Infect Dis | pmid:28244378 |
| Bergeron A et al. | Effect of Azithromycin on Airflow Decline-Free Survival After Allogeneic Hematopoietic Stem Cell Transplant: The ALLOZITHRO Randomized Clinical Trial. | 2017 | JAMA | pmid:28787506 |
| Zhang M et al. | Electrophysiologic Studies on the Risks and Potential Mechanism Underlying the Proarrhythmic Nature of Azithromycin. | 2017 | Cardiovasc. Toxicol. | pmid:28213753 |
| Hoogewoud F et al. | Prognostic Factors in Syphilitic Uveitis. | 2017 | Ophthalmology | pmid:28779905 |
| Lahra MM et al. | Treatment guidelines after an outbreak of azithromycin-resistant Neisseria gonorrhoeae in South Australia. | 2017 | Lancet Infect Dis | pmid:28134103 |
| Bloch EM et al. | Antibiotic Resistance in Young Children in Kilosa District, Tanzania 4 Years after Mass Distribution of Azithromycin for Trachoma Control. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28722638 |
| O'Brien KS et al. | Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28722569 |
| Stoney RJ et al. | Travelers' Diarrhea and Other Gastrointestinal Symptoms Among Boston-Area International Travelers. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28719282 |
| Stieger N et al. | Solution-mediated crystallization of amorphous azithromycin. | 2017 | Pharmazie | pmid:29441902 |
| Feng X and Liu J | A combination of irsogladine maleate and azithromycin exhibits addictive protective effects in LPS-induced human gingival epithelial cells. | 2017 | Pharmazie | pmid:29441859 |
| González-Beiras C et al. | Yaws Osteoperiostitis Treated with Single-Dose Azithromycin. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28193743 |
| Ivanová L et al. | Estimation of amount of selected pharmaceuticals sorbed onto digested sludge from wastewater treatment plant Bratislava-Petržalka. | 2017 | Environ. Res. | pmid:28183039 |
| Thakur SD et al. | Resistance to Ceftriaxone and Azithromycin in Neisseria gonorrhoeae Isolates From 7 Countries of South America and the Caribbean: 2010-2011. | 2017 | Sex Transm Dis | pmid:28178114 |
| Boggess KA et al. | Risk Factors for Postcesarean Maternal Infection in a Trial of Extended-Spectrum Antibiotic Prophylaxis. | 2017 | Obstet Gynecol | pmid:28178058 |
| Ullah S et al. | Creatinine-based non-phospholipid vesicular carrier for improved oral bioavailability of Azithromycin. | 2017 | Drug Dev Ind Pharm | pmid:28157445 |
| Hallström H et al. | Open flap debridement of peri-implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial. | 2017 | J. Clin. Periodontol. | pmid:28836279 |
| Subedi Y | Around Manaslu Ultramarathon: Diarrhea Is Still the King. | 2017 | Wilderness Environ Med | pmid:28735656 |
| McConnell K and Shields M | Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years. | 2017 | Arch Dis Child Educ Pract Ed | pmid:28735295 |
| Gibson PG et al. | Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. | 2017 | Lancet | pmid:28687413 |
| Bojang E et al. | Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control. | 2017 | BMC Microbiol. | pmid:28351345 |
| Kong FY et al. | Pharmacokinetics of a single 1g dose of azithromycin in rectal tissue in men. | 2017 | PLoS ONE | pmid:28350806 |
| Bornstein M et al. | Factors Associated With Primary Care Physician Knowledge of the Recommended Regimen for Treating Gonorrhea. | 2017 | Sex Transm Dis | pmid:27898574 |
| Checa R et al. | Efficacy, safety and tolerance of imidocarb dipropionate versus atovaquone or buparvaquone plus azithromycin used to treat sick dogs naturally infected with the Babesia microti-like piroplasm. | 2017 | Parasit Vectors | pmid:28292316 |
| Ishiguro N et al. | Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients. | 2017 | PLoS ONE | pmid:28288170 |
| Babić I et al. | Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion. | 2017 | Eur Arch Otorhinolaryngol | pmid:27873023 |
| Demczuk W et al. | Neisseria gonorrhoeae Sequence Typing for Antimicrobial Resistance, a Novel Antimicrobial Resistance Multilocus Typing Scheme for Tracking Global Dissemination of N. gonorrhoeae Strains. | 2017 | J. Clin. Microbiol. | pmid:28228492 |
| Yan M et al. | Synthesis and antibacterial activity of novel 3-O-descladinosylazithromycin derivatives. | 2017 | Eur J Med Chem | pmid:27836198 |
| Ginouvès M et al. | In Vitro Sensitivity of Cutaneous Leishmania Promastigote Isolates Circulating in French Guiana to a Set of Drugs. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28167598 |
| Haque F et al. | Evaluation of a Smartphone Decision-Support Tool for Diarrheal Disease Management in a Resource-Limited Setting. | 2017 | PLoS Negl Trop Dis | pmid:28103233 |
| Agarwal E et al. | Locally Delivered 0.5% Azithromycin as an Adjunct to Non-Surgical Treatment in Patients With Chronic Periodontitis With Type 2 Diabetes: A Randomized Controlled Clinical Trial. | 2017 | J. Periodontol. | pmid:22655911 |
| Giguère S | Treatment of Infections Caused by Rhodococcus equi. | 2017 | Vet. Clin. North Am. Equine Pract. | pmid:28161038 |
| Daimee UA et al. | A 77-year-old man with fever and night sweats. | 2017 | Eur. J. Intern. Med. | pmid:27765389 |
| Illia R et al. | Role of cervical cerclage and prolonged antibiotic therapy with azithromycin in patients with previous perinatal loss amnionitis. | 2017 | J. Matern. Fetal. Neonatal. Med. | pmid:27094535 |
| Massip C et al. | Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump. | 2017 | J. Antimicrob. Chemother. | pmid:28137939 |
| Jover-GarcÃa J et al. | [In-vitro activity of azithromycin in faecal isolates of Aeromonas hydrophila]. | 2017 | An Pediatr (Barc) | pmid:27686393 |
| Terkelsen D et al. | Multidrug-resistant infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. | 2017 | Euro Surveill. | pmid:29067905 |
| Srivastava S et al. | A 'shock and awe' thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium-intracellulare complex disease. | 2017 | J. Antimicrob. Chemother. | pmid:28922810 |
| Srivastava S et al. | Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance. | 2017 | J. Antimicrob. Chemother. | pmid:28922805 |
| Cole MJ et al. | Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015. | 2017 | BMC Infect. Dis. | pmid:28893203 |
| Xue Y et al. | An in vitro model of azithromycin-induced persistent Chlamydia trachomatis infection. | 2017 | FEMS Microbiol. Lett. | pmid:28854672 |
| Garcia-Vidal C et al. | Levofloxacin versus azithromycin for treating legionella pneumonia: a propensity score analysis. | 2017 | Clin. Microbiol. Infect. | pmid:28267637 |
| Salman S et al. | Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling. | 2017 | Antimicrob. Agents Chemother. | pmid:28242669 |
| Mathew A et al. | Antimicrobial and Immunomodulatory Surface-Functionalized Electrospun Membranes for Bone Regeneration. | 2017 | Adv Healthc Mater | pmid:28240815 |
| Teng F et al. | In vitro characterization of pH-sensitive azithromycin-loaded methoxy poly (ethylene glycol)-block-poly (aspartic acid-graft-imidazole) micelles. | 2017 | J Colloid Interface Sci | pmid:28209540 |
| Koop AH et al. | 56-Year-Old Woman With Cough and Fatigue for 1 Week. | 2017 | Mayo Clin. Proc. | pmid:28110893 |
| Murray K et al. | Increasing Antibiotic Resistance in Shigella spp. from Infected New York City Residents, New York, USA. | 2017 | Emerging Infect. Dis. | pmid:28098543 |
| Quinn KL et al. | Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. | 2017 | Drug Saf | pmid:28421551 |