Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dunne MW | Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trial. | 2000 | J. Infect. Dis. | pmid:10839762 |
| Anderson JL and Muhlestein JB | The ACADEMIC study in perspective (Azithromycin in coronary artery disease: elimination of myocardial infection with Chlamydia). | 2000 | J. Infect. Dis. | pmid:10839761 |
| Matute AJ et al. | Is a 5 day course of azithromycin enough for infections caused by Legionella pneumophila? | 2000 | J. Antimicrob. Chemother. | pmid:10837459 |
| Moshkani SK and Dalimi A | Evaluation of the efficacy of atovaquone alone or in combination with azithromycin against acute murine toxoplasmosis. | 2000 | Vet. Res. Commun. | pmid:10836275 |
| Straubinger RK | PCR-Based quantification of Borrelia burgdorferi organisms in canine tissues over a 500-Day postinfection period. | 2000 | J. Clin. Microbiol. | pmid:10834975 |
| Mirmiran R et al. | Disseminated gonococcal infection: a case of beta-lactamase-producing Neisseria gonorrhoeae. | 2000 | J Am Podiatr Med Assoc | pmid:10833879 |
| Zuckerman JM | The newer macrolides: azithromycin and clarithromycin. | 2000 | Infect. Dis. Clin. North Am. | pmid:10829265 |
| Bin XX et al. | Effect of azithromycin plus rifampin versus amoxicillin alone on eradication and inflammation in the chronic course of Chlamydia pneumoniae pneumonitis in mice. | 2000 | Antimicrob. Agents Chemother. | pmid:10817751 |
| Tsitsika A et al. | Single-oral-dose azithromycin prophylaxis against experimental streptococcal or staphylococcal aortic valve endocarditis. | 2000 | Antimicrob. Agents Chemother. | pmid:10817749 |
| Turcinov D et al. | Failure of azithromycin in treatment of Brill-Zinsser disease. | 2000 | Antimicrob. Agents Chemother. | pmid:10817744 |
| Vergis EN et al. | Azithromycin vs cefuroxime plus erythromycin for empirical treatment of community-acquired pneumonia in hospitalized patients: a prospective, randomized, multicenter trial. | 2000 | Arch. Intern. Med. | pmid:10809032 |
| Sasaki TY and Sumida KN | Angioimmunoblastic T-cell lymphoma (AIL-TCL) following macrolide administration. | 2000 | Hawaii Med J | pmid:10800250 |
| Kozyrskyj AL et al. | Short course antibiotics for acute otitis media. | 2000 | Cochrane Database Syst Rev | pmid:10796591 |
| Skerk V et al. | Comparative analysis of azithromycin and doxycycline efficacy in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum. | 2000 | J Chemother | pmid:10789560 |
| Miller SA et al. | Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human vascular smooth muscle and induces cellular proliferation. | 2000 | J. Surg. Res. | pmid:10781378 |
| Ress BD and Gross EM | Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. | 2000 | Ann. Otol. Rhinol. Laryngol. | pmid:10778901 |
| Bujanda L et al. | Ranitidine bismuth citrate plus azithromycin for Helicobacter pylori eradication. | 2000 | J. Clin. Gastroenterol. | pmid:10777206 |
| Donders GG | Treatment of sexually transmitted bacterial diseases in pregnant women. | 2000 | Drugs | pmid:10776830 |
| Laming AC et al. | A targeted, single-dose azithromycin strategy for trachoma. | 2000 | Med. J. Aust. | pmid:10772587 |
| Najib MM et al. | Cost-effectiveness of sparfloxacin compared with other oral antimicrobials in outpatient treatment of community-acquired pneumonia. | 2000 | Pharmacotherapy | pmid:10772376 |
| Brieland JK et al. | Efficacy of SCH27899 in an animal model of Legionnaires' disease using immunocompromised A/J mice. | 2000 | Antimicrob. Agents Chemother. | pmid:10770771 |
| El-Sadr WM et al. | Discontinuation of prophylaxis for Mycobacterium avium complex disease in HIV-infected patients who have a response to antiretroviral therapy. Terry Beirn Community Programs for Clinical Research on AIDS. | 2000 | N. Engl. J. Med. | pmid:10766581 |
| Somani J et al. | Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure. | 2000 | J. Infect. Dis. | pmid:10762573 |
| Diculencu D et al. | [The postantibiotic effect of azithromycin on respiratory pathogens]. | 1998 Jul-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:10756861 |
| Wenisch C | [Pharmacokinetic effects of antibiotics on the development of bacterial resistance particularly in reference to azithromycin]. | 2000 | Wien Med Wochenschr | pmid:10756595 |
| Nishi Y et al. | [Effect of macrolide antibiotics on adhesion by cancer cells]. | 2000 | Jpn J Antibiot | pmid:10756450 |
| Giacometti A et al. | Activity of nitazoxanide alone and in combination with azithromycin and rifabutin against Cryptosporidium parvum in cell culture. | 2000 | J. Antimicrob. Chemother. | pmid:10747821 |
| Schissel DJ et al. | Azithromycin eruption in infectious mononucleosis: a proposed mechanism of interaction. | 2000 | Cutis | pmid:10738636 |
| Ouchi K | Chlamydia pneumoniae and atherosclerosis. | 1999 | Jpn. J. Infect. Dis. | pmid:10738358 |
| Potts JM et al. | Association of chronic urinary symptoms in women and Ureaplasma urealyticum. | 2000 | Urology | pmid:10736488 |
| Canut Blasco A et al. | [A randomized, prospective and comparative study is a clinical trial]. | 2000 | Med Clin (Barc) | pmid:10734631 |
| Rino BE et al. | Azithromycin in the treatment of plasmodium falciparum gametocytes: a preliminary observation. | 2000 | J. Trop. Pediatr. | pmid:10730047 |
| Angelilli ML et al. | Palatability of oral antibiotics among children in an urban primary care center. | 2000 | Arch Pediatr Adolesc Med | pmid:10710025 |
| Slavinsky J et al. | Factors associated with the decline in sexually transmitted infections among HIV-positive women. | 2000 | J. Acquir. Immune Defic. Syndr. | pmid:10708065 |
| Giacometti A et al. | Anticryptosporidial activity of ranalexin, lasalocid and azithromycin alone and in combination in cell lines. | 2000 | J. Antimicrob. Chemother. | pmid:10702561 |
| Bowden FJ et al. | Donovanosis causing cervical lymphadenopathy in a five-month-old boy. | 2000 | Pediatr. Infect. Dis. J. | pmid:10694010 |
| Dagan R et al. | Bacteriologic and clinical efficacy of amoxicillin/clavulanate vs. azithromycin in acute otitis media. | 2000 | Pediatr. Infect. Dis. J. | pmid:10693993 |
| Giacometti A et al. | Efficacy of treatment with paromomycin, azithromycin, and nitazoxanide in a patient with disseminated cryptosporidiosis. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10691200 |
| Lo SH et al. | Azithromycin-induced hearing loss. | 1999 | Am J Health Syst Pharm | pmid:10690220 |
| Steen R et al. | Evidence of declining STD prevalence in a South African mining community following a core-group intervention. | 2000 | Sex Transm Dis | pmid:10654860 |
| Fernandez-Obregon AC | Azithromycin for the treatment of acne. | 2000 | Int. J. Dermatol. | pmid:10651967 |
| Morita JY et al. | Impact of azithromycin on oropharyngeal carriage of group A Streptococcus and nasopharyngeal carriage of macrolide-resistant Streptococcus pneumoniae. | 2000 | Pediatr. Infect. Dis. J. | pmid:10643849 |
| Karpov OI | [The clinical and economic efficacies of short courses of azithromycin in acute sinusitis]. | 1999 | Antibiot. Khimioter. | pmid:10635419 |
| Vcev A et al. | Pantoprazole, amoxycillin and either azithromycin or clarithromycin for eradication of Helicobacter pylori in duodenal ulcer. | 2000 | Aliment. Pharmacol. Ther. | pmid:10632647 |
| Puri SK and Singh N | Azithromycin: antimalarial profile against blood- and sporozoite-induced infections in mice and monkeys. | 2000 | Exp. Parasitol. | pmid:10631075 |
| Burgess DS et al. | A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. | 1999 | Ann Pharmacother | pmid:10630825 |
| National guideline for the management of donovanosis (granuloma inguinale). Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616381 | |
| Bowden FJ and Skov SJ | Treating donovanosis. | 1999 | Aust Fam Physician | pmid:10615749 |
| Ianaro A et al. | Anti-inflammatory activity of macrolide antibiotics. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10604943 |
| Dagan R et al. | Bacteriologic efficacies of oral azithromycin and oral cefaclor in treatment of acute otitis media in infants and young children. | 2000 | Antimicrob. Agents Chemother. | pmid:10602721 |