Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wynn RF et al. | Azithromycin for cerebral toxoplasmosis in AIDS. | 1993 | Lancet | pmid:8093526 |
| Fortner JH et al. | Tapetal effect of an azalide antibiotic following oral administration in beagle dogs. | 1993 | Fundam Appl Toxicol | pmid:8405779 |
| Narcio Reyes LE et al. | [Efficacy and safety of azithromycin in the treatment of female genital Chlamydia trachomatis infections]. | 1993 | Ginecol Obstet Mex | pmid:8406112 |
| Cameron DJ | Effectiveness of early Lyme disease treatment. | 1993 | Am. J. Med. | pmid:8388627 |
| Melski JW et al. | Primary and secondary erythema migrans in central Wisconsin. | 1993 | Arch Dermatol | pmid:8389536 |
| Lopatkin NA et al. | [Use of azithromycin ("Sumamded") in the treatment of infectious-inflammatory diseases of the lower urinary tract and male genitalia]. | 1993 | Antibiot. Khimioter. | pmid:8060189 |
| Saba J et al. | Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. | 1993 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8112357 |
| Weiss LM et al. | Efficacy of azithromycin for treating Babesia microti infection in the hamster model. | 1993 | J. Infect. Dis. | pmid:8228366 |
| Holdcroft C | Two new macrolide antibiotics: clarithromycin and azithromycin. | 1993 | Nurse Pract | pmid:8380492 |
| Lazarova Z et al. | Azithromycin (Sumamed-Pliva) in the treatment of chlamydial genital tract infections in infertile marriages. | 1992 Nov-Dec | Int J STD AIDS | pmid:1337473 |
| Farthing C et al. | Azithromycin for cerebral toxoplasmosis. | 1992 | Lancet | pmid:1346707 |
| Chave JP et al. | Once-a-week azithromycin in AIDS patients: tolerability, kinetics, and effects on zidovudine disposition. | 1992 | Antimicrob. Agents Chemother. | pmid:1324635 |
| Derouin F et al. | Synergistic activity of azithromycin and pyrimethamine or sulfadiazine in acute experimental toxoplasmosis. | 1992 | Antimicrob. Agents Chemother. | pmid:1324642 |
| Vallée E et al. | Activity and local delivery of azithromycin in a mouse model of Haemophilus influenzae lung infection. | 1992 | Antimicrob. Agents Chemother. | pmid:1324644 |
| Mertens JC et al. | Double-blind randomized study comparing the efficacies and safeties of a short (3-day) course of azithromycin and a 5-day course of amoxicillin in patients with acute exacerbations of chronic bronchitis. | 1992 | Antimicrob. Agents Chemother. | pmid:1324645 |
| Hammerschlag MR et al. | In vitro activities of azithromycin, clarithromycin, L-ofloxacin, and other antibiotics against Chlamydia pneumoniae. | 1992 | Antimicrob. Agents Chemother. | pmid:1324650 |
| Paulsen P et al. | Influence of azithromycin and other macrolides on the intracellular killing of Staphylococcus aureus by human polymorphonuclear leucocytes of healthy donors and a patient with Chédiak-Higashi syndrome. | 1992 | Chemotherapy | pmid:1324831 |
| Martin DH et al. | A controlled trial of a single dose of azithromycin for the treatment of chlamydial urethritis and cervicitis. The Azithromycin for Chlamydial Infections Study Group. | 1992 | N. Engl. J. Med. | pmid:1325036 |
| Gingras BA and Jensen JB | Activity of azithromycin (CP-62,993) and erythromycin against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro. | 1992 | Am. J. Trop. Med. Hyg. | pmid:1326232 |
| Pajukanta R et al. | In vitro activity of azithromycin compared with that of erythromycin against Actinobacillus actinomycetemcomitans. | 1992 | Antimicrob. Agents Chemother. | pmid:1329617 |
| Bonnet M and Van der Auwera P | In vitro and in vivo intraleukocytic accumulation of azithromycin (CP-62, 993) and its influence on ex vivo leukocyte chemiluminescence. | 1992 | Antimicrob. Agents Chemother. | pmid:1329619 |
| Cynamon MH and Klemens SP | Activity of azithromycin against Mycobacterium avium infection in beige mice. | 1992 | Antimicrob. Agents Chemother. | pmid:1329622 |
| Ballow CH and Amsden GW | Azithromycin: the first azalide antibiotic. | 1992 | Ann Pharmacother | pmid:1330097 |
| Nilsen A et al. | A double blind study of single dose azithromycin and doxycycline in the treatment of chlamydial urethritis in males. | 1992 | Genitourin Med | pmid:1330880 |
| Jones AB and Herbert CM | The in vitro profile of selected 14-membered azalides. | 1992 | J. Antibiot. | pmid:1334956 |
| Engel JN | Azithromycin-induced block of elementary body formation in Chlamydia trachomatis. | 1992 | Antimicrob. Agents Chemother. | pmid:1280057 |
| Peters DH et al. | Azithromycin. A review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy. | 1992 | Drugs | pmid:1280567 |
| Neu HC | New macrolide antibiotics: azithromycin and clarithromycin. | 1992 | Ann. Intern. Med. | pmid:1310839 |
| Massarotti EM et al. | Treatment of early Lyme disease. | 1992 | Am. J. Med. | pmid:1313637 |
| Pruul H and McDonald PJ | Potentiation of antibacterial activity of azithromycin and other macrolides by normal human serum. | 1992 | Antimicrob. Agents Chemother. | pmid:1317141 |
| Brown BA et al. | Activities of four macrolides, including clarithromycin, against Mycobacterium fortuitum, Mycobacterium chelonae, and M. chelonae-like organisms. | 1992 | Antimicrob. Agents Chemother. | pmid:1317144 |
| Kobrehel G et al. | Synthesis and antibacterial activity of O-methylazithromycin derivatives. | 1992 | J. Antibiot. | pmid:1317368 |
| Welsh LE et al. | In vitro evaluation of activities of azithromycin, erythromycin, and tetracycline against Chlamydia trachomatis and Chlamydia pneumoniae. | 1992 | Antimicrob. Agents Chemother. | pmid:1318677 |
| Bahal N and Nahata MC | The new macrolide antibiotics: azithromycin, clarithromycin, dirithromycin, and roxithromycin. | 1992 | Ann Pharmacother | pmid:1318761 |
| Drew RH and Gallis HA | Azithromycin--spectrum of activity, pharmacokinetics, and clinical applications. | 1992 | Pharmacotherapy | pmid:1319048 |
| Frank MO et al. | In vitro demonstration of transport and delivery of antibiotics by polymorphonuclear leukocytes. | 1992 | Antimicrob. Agents Chemother. | pmid:1336337 |
| O'Reilly T et al. | Relationship between antibiotic concentration in bone and efficacy of treatment of staphylococcal osteomyelitis in rats: azithromycin compared with clindamycin and rifampin. | 1992 | Antimicrob. Agents Chemother. | pmid:1336342 |
| Felstead SJ and Daniel R | Short-course treatment of sinusitis and other upper respiratory tract infections with azithromycin: a comparison with erythromycin and amoxycillin. European Azithromycin Study Group. | 1991 Sep-Oct | J. Int. Med. Res. | pmid:1660823 |
| Daniel R | Simplified treatment of acute lower respiratory tract infection with azithromycin: a comparison with erythromycin and amoxycillin. European Azithromycin Study Group. | 1991 Sep-Oct | J. Int. Med. Res. | pmid:1660824 |
| Rehg JE | Anti-cryptosporidial activity of macrolides in immunosuppressed rats. | 1991 Nov-Dec | J. Protozool. | pmid:1667930 |
| Kimata I et al. | Chemotherapeutic effect of azithromycin and lasalocid on Cryptosporidium infection in mice. | 1991 Nov-Dec | J. Protozool. | pmid:1667931 |
| Daniel R | Azithromycin, erythromycin and cloxacillin in the treatment of infections of skin and associated soft tissues. European Azithromycin Study Group. | 1991 Nov-Dec | J. Int. Med. Res. | pmid:1663466 |
| Ball AP | Azithromycin: an interim analysis. | 1991 Nov-Dec | J. Int. Med. Res. | pmid:1663467 |
| Waugh MA | Azithromycin in sexually transmitted diseases--an overview. | 1991 Jul-Aug | Int J STD AIDS | pmid:1655055 |
| Whatley JD et al. | Azithromycin vs doxycycline in the treatment of non-gonococcal urethritis. | 1991 Jul-Aug | Int J STD AIDS | pmid:1655056 |
| Stuhne-Sekalec L et al. | Liposomes as carriers of macrolides: preferential association of erythromycin A and azithromycin with liposomes of phosphatidylglycerol containing unsaturated fatty acid(s). | 1991 Apr-Jun | J Microencapsul | pmid:1662717 |
| Clarithro- and azithromycin--better erythromycins? | 1991 | Drug Ther Bull | pmid:1665125 | |
| Bermudez LE et al. | Stimulation with cytokines enhances penetration of azithromycin into human macrophages. | 1991 | Antimicrob. Agents Chemother. | pmid:1667256 |
| Young LS et al. | Azithromycin for treatment of Mycobacterium avium-intracellulare complex infection in patients with AIDS. | 1991 | Lancet | pmid:1682544 |
| Davila D et al. | Pharmacokinetics of azithromycin after single oral dosing of experimental animals. | 1991 | Biopharm Drug Dispos | pmid:1657238 |