Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Staphylococcal Infections D013203 15 associated lipids
HIV Seropositivity D006679 15 associated lipids
Neutropenia D009503 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Angina, Unstable D000789 14 associated lipids
Stomatitis D013280 14 associated lipids
Sarcoidosis D012507 13 associated lipids
Multiple Myeloma D009101 13 associated lipids
Pain, Postoperative D010149 13 associated lipids
Airway Obstruction D000402 13 associated lipids
Urticaria D014581 13 associated lipids
Rosacea D012393 13 associated lipids
Abscess D000038 13 associated lipids
Wound Infection D014946 12 associated lipids
Otitis Media D010033 12 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Skin Neoplasms D012878 12 associated lipids
Endophthalmitis D009877 12 associated lipids
Eye Diseases D005128 12 associated lipids
Cat Diseases D002371 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Crohn Disease D003424 12 associated lipids
Exanthema D005076 11 associated lipids
Shock, Septic D012772 11 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Scalp Dermatoses D012536 11 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Pregnancy Complications, Infectious D011251 11 associated lipids
Long QT Syndrome D008133 10 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Osteitis D010000 10 associated lipids
Dyspnea D004417 10 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Hearing Disorders D006311 10 associated lipids
Pancreatitis D010195 10 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Sinusitis D012852 9 associated lipids
Toxoplasmosis D014123 9 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Keratosis D007642 9 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Rehg JE Anti-cryptosporidial activity of macrolides in immunosuppressed rats. 1991 Nov-Dec J. Protozool. pmid:1667930
Daniel R Azithromycin, erythromycin and cloxacillin in the treatment of infections of skin and associated soft tissues. European Azithromycin Study Group. 1991 Nov-Dec J. Int. Med. Res. pmid:1663466
Ball AP Azithromycin: an interim analysis. 1991 Nov-Dec J. Int. Med. Res. pmid:1663467
Waugh MA Azithromycin in sexually transmitted diseases--an overview. 1991 Jul-Aug Int J STD AIDS pmid:1655055
Whatley JD et al. Azithromycin vs doxycycline in the treatment of non-gonococcal urethritis. 1991 Jul-Aug Int J STD AIDS pmid:1655056
Stuhne-Sekalec L et al. Liposomes as carriers of macrolides: preferential association of erythromycin A and azithromycin with liposomes of phosphatidylglycerol containing unsaturated fatty acid(s). 1991 Apr-Jun J Microencapsul pmid:1662717
Clarithro- and azithromycin--better erythromycins? 1991 Drug Ther Bull pmid:1665125
Young LS et al. Azithromycin for treatment of Mycobacterium avium-intracellulare complex infection in patients with AIDS. 1991 Lancet pmid:1682544
Foulds G et al. The effects of an antacid or cimetidine on the serum concentrations of azithromycin. 1991 J Clin Pharmacol pmid:1849152
Edelstein PH and Edelstein MA In vitro activity of azithromycin against clinical isolates of Legionella species. 1991 Antimicrob. Agents Chemother. pmid:1849708
Neu HC Clinical microbiology of azithromycin. 1991 Am. J. Med. pmid:1656736
Stamm WE Azithromycin in the treatment of uncomplicated genital chlamydial infections. 1991 Am. J. Med. pmid:1656737
Hooton TM A comparison of azithromycin and penicillin V for the treatment of streptococcal pharyngitis. 1991 Am. J. Med. pmid:1656738
Casiano RR Azithromycin and amoxicillin in the treatment of acute maxillary sinusitis. 1991 Am. J. Med. pmid:1656739
Dark D Multicenter evaluation of azithromycin and cefaclor in acute lower respiratory tract infections. 1991 Am. J. Med. pmid:1656740
Mallory SB Azithromycin compared with cephalexin in the treatment of skin and skin structure infections. 1991 Am. J. Med. pmid:1656741
Azoulay-Dupuis E et al. Prophylactic and therapeutic activities of azithromycin in a mouse model of pneumococcal pneumonia. 1991 Antimicrob. Agents Chemother. pmid:1656849
Amacher DE et al. Comparison of the effects of the new azalide antibiotic, azithromycin, and erythromycin estolate on rat liver cytochrome P-450. 1991 Antimicrob. Agents Chemother. pmid:1656856
Johnson RB The role of azalide antibiotics in the treatment of Chlamydia. 1991 Am. J. Obstet. Gynecol. pmid:1645503
Gelber RH et al. Activities of various macrolide antibiotics against Mycobacterium leprae infection in mice. 1991 Antimicrob. Agents Chemother. pmid:1648889