Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diarrhea D003967 32 associated lipids
Digestive System Diseases D004066 3 associated lipids
Dog Diseases D004283 5 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Dry Socket D004368 3 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Dyspnea D004417 10 associated lipids
Ectodermal Dysplasia D004476 1 associated lipids
Edema D004487 152 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Elephantiasis D004604 2 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Enteritis D004751 8 associated lipids
Epiglottitis D004826 1 associated lipids
Erythema Nodosum D004893 5 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Exanthema D005076 11 associated lipids
Eye Diseases D005128 12 associated lipids
Eyelid Diseases D005141 4 associated lipids
Fatty Liver D005234 48 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Fever D005334 35 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Furunculosis D005667 2 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Giardiasis D005873 3 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Gonorrhea D006069 7 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Haemophilus Infections D006192 3 associated lipids
Hearing Disorders D006311 10 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Heartburn D006356 2 associated lipids
Hemolysis D006461 131 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Herpes Genitalis D006558 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hoarseness D006685 2 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperglycemia D006943 21 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Onyeji CO et al. Activities of clarithromycin, azithromycin, and ofloxacin in combination with liposomal or unencapsulated granulocyte-macrophage colony-stimulating factor against intramacrophage Mycobacterium avium-Mycobacterium intracellulare. 1995 J. Infect. Dis. pmid:7658075
Debets-Ossenkopp YJ et al. Effect of an acidic environment on the susceptibility of Helicobacter pylori to trospectomycin and other antimicrobial agents. 1995 Eur. J. Clin. Microbiol. Infect. Dis. pmid:7649202
Adal KA et al. Photo quiz. Bacillary angiomatosis. 1995 Clin. Infect. Dis. pmid:7727641
Bermudez LE et al. Efficacy of azithromycin and rifabutin in preventing infection by Mycobacterium avium complex in beige mice. 1995 J. Antimicrob. Chemother. pmid:8591938
Clancy J et al. Assays to detect and characterize synthetic agents that inhibit the ErmC methyltransferase. 1995 J. Antibiot. pmid:8557568
Amsden GW Macrolides versus azalides: a drug interaction update. 1995 Ann Pharmacother pmid:8547740
Beckers CJ et al. Inhibition of cytoplasmic and organellar protein synthesis in Toxoplasma gondii. Implications for the target of macrolide antibiotics. 1995 J. Clin. Invest. pmid:7814637
Friis HM [Azithromycin--an exciting new antibiotic]. 1995 Ugeskr. Laeg. pmid:7831724
Tajima T et al. [Pharmacokinetic and clinical studies with azithromycin (fine granule) in the pediatric field. Pediatric Study Group of Azithromycin]. 1995 Jpn J Antibiot pmid:7474329
Dessau RB [Azithromycin]. 1995 Ugeskr. Laeg. pmid:7831733
Fujii R et al. [Pharmacokinetic and clinical studies with azithromycin (capsule) in the pediatric field. Pediatric Study Group of Azithromycin]. 1995 Jpn J Antibiot pmid:7474330
Goldstein EJ et al. Comparative in vitro activities of azithromycin, Bay y 3118, levofloxacin, sparfloxacin, and 11 other oral antimicrobial agents against 194 aerobic and anaerobic bite wound isolates. 1995 Antimicrob. Agents Chemother. pmid:7625795
Barry AL et al. Relative potencies of azithromycin, clarithromycin and five other orally administered antibiotics. 1995 J. Antimicrob. Chemother. pmid:7628991
Stamm WE et al. Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. 1995 JAMA pmid:7629982
Schmid GP and Fontanarosa PB Evolving strategies for management of the nongonococcal urethritis syndrome. 1995 JAMA pmid:7629989
Sadiq ST et al. Effects of azithromycin on malariometric indices in The Gambia. 1995 Lancet pmid:7564674
Wawer MJ et al. AIDS intervention in Uganda. 1995 Science pmid:7570005
Amland PF et al. A prospective, double-blind, placebo-controlled trial of a single dose of azithromycin on postoperative wound infections in plastic surgery. 1995 Plast. Reconstr. Surg. pmid:7480237
Worm AM and Osterlind A Azithromycin levels in cervical mucus and plasma after a single 1.0g oral dose for chlamydial cervicitis. 1995 Genitourin Med pmid:7590717
Gastearena I et al. Determination of the alpha1-acid glycoprotein binding of azithromycin in vitro by equilibrium dialysis. 1995 J Chemother pmid:8904095