Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diarrhea D003967 32 associated lipids
Digestive System Diseases D004066 3 associated lipids
Dog Diseases D004283 5 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Dry Socket D004368 3 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Dyspnea D004417 10 associated lipids
Ectodermal Dysplasia D004476 1 associated lipids
Edema D004487 152 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Elephantiasis D004604 2 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Enteritis D004751 8 associated lipids
Epiglottitis D004826 1 associated lipids
Erythema Nodosum D004893 5 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Exanthema D005076 11 associated lipids
Eye Diseases D005128 12 associated lipids
Eyelid Diseases D005141 4 associated lipids
Fatty Liver D005234 48 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Fever D005334 35 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Furunculosis D005667 2 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Giardiasis D005873 3 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Gonorrhea D006069 7 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Haemophilus Infections D006192 3 associated lipids
Hearing Disorders D006311 10 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Heartburn D006356 2 associated lipids
Hemolysis D006461 131 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Herpes Genitalis D006558 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hoarseness D006685 2 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperglycemia D006943 21 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Ribeiro M et al. Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells. 2017 Exp. Parasitol. pmid:28803905
Benn K et al. Bradycardia and Hypothermia Complicating Azithromycin Treatment. 2017 Am J Case Rep pmid:28798290
Mei J et al. Implications of intrapartum azithromycin on neonatal microbiota. 2017 Lancet Infect Dis pmid:28244378
Bergeron A et al. Effect of Azithromycin on Airflow Decline-Free Survival After Allogeneic Hematopoietic Stem Cell Transplant: The ALLOZITHRO Randomized Clinical Trial. 2017 JAMA pmid:28787506
Feng X and Liu J A combination of irsogladine maleate and azithromycin exhibits addictive protective effects in LPS-induced human gingival epithelial cells. 2017 Pharmazie pmid:29441859
González-Beiras C et al. Yaws Osteoperiostitis Treated with Single-Dose Azithromycin. 2017 Am. J. Trop. Med. Hyg. pmid:28193743
Ivanová L et al. Estimation of amount of selected pharmaceuticals sorbed onto digested sludge from wastewater treatment plant Bratislava-Petržalka. 2017 Environ. Res. pmid:28183039
Hallström H et al. Open flap debridement of peri-implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial. 2017 J. Clin. Periodontol. pmid:28836279
Subedi Y Around Manaslu Ultramarathon: Diarrhea Is Still the King. 2017 Wilderness Environ Med pmid:28735656
Kong FY et al. Pharmacokinetics of a single 1g dose of azithromycin in rectal tissue in men. 2017 PLoS ONE pmid:28350806
Bornstein M et al. Factors Associated With Primary Care Physician Knowledge of the Recommended Regimen for Treating Gonorrhea. 2017 Sex Transm Dis pmid:27898574
Checa R et al. Efficacy, safety and tolerance of imidocarb dipropionate versus atovaquone or buparvaquone plus azithromycin used to treat sick dogs naturally infected with the Babesia microti-like piroplasm. 2017 Parasit Vectors pmid:28292316
Ishiguro N et al. Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients. 2017 PLoS ONE pmid:28288170
Babić I et al. Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion. 2017 Eur Arch Otorhinolaryngol pmid:27873023
Daimee UA et al. A 77-year-old man with fever and night sweats. 2017 Eur. J. Intern. Med. pmid:27765389
Terkelsen D et al. Multidrug-resistant infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. 2017 Euro Surveill. pmid:29067905
Srivastava S et al. A 'shock and awe' thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium-intracellulare complex disease. 2017 J. Antimicrob. Chemother. pmid:28922810
Salman S et al. Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling. 2017 Antimicrob. Agents Chemother. pmid:28242669
Mathew A et al. Antimicrobial and Immunomodulatory Surface-Functionalized Electrospun Membranes for Bone Regeneration. 2017 Adv Healthc Mater pmid:28240815
Quinn KL et al. Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. 2017 Drug Saf pmid:28421551