Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Liang JY et al. | Azithromycin-resistant Neisseria gonorrhoeae isolates in Guangzhou, China (2009-2013): coevolution with decreased susceptibilities to ceftriaxone and genetic characteristics. | 2016 | BMC Infect. Dis. | pmid:27080231 |
| Hu J et al. | Streptococcus pneumoniae and Haemophilus influenzae type b carriage in Chinese children aged 12-18 months in Shanghai, China: a cross-sectional study. | 2016 | BMC Infect. Dis. | pmid:27080523 |
| Poizeau F et al. | [Shifting cellulitis in a patient with X-linked hypogammaglobulinemia]. | Ann Dermatol Venereol | pmid:27080822 | |
| Li X et al. | Macrolides use and the risk of sudden cardiac death. | 2016 | Expert Rev Anti Infect Ther | pmid:27086751 |
| Guo Y et al. | Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. | 2016 | Viruses | pmid:27089359 |
| Ni C et al. | High prevalence of Neisseria gonorrhoeae with high-level resistance to azithromycin in Hangzhou, China. | 2016 | J. Antimicrob. Chemother. | pmid:27090631 |
| Wang Z and Meenach SA | Synthesis and Characterization of Nanocomposite Microparticles (nCmP) for the Treatment of Cystic Fibrosis-Related Infections. | 2016 | Pharm. Res. | pmid:27091030 |
| Illia R et al. | Role of cervical cerclage and prolonged antibiotic therapy with azithromycin in patients with previous perinatal loss amnionitis. | 2017 | J. Matern. Fetal. Neonatal. Med. | pmid:27094535 |
| Topp E et al. | Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. | 2016 | Sci. Total Environ. | pmid:27096634 |
| Vermeersch K et al. | The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial. | 2016 | Int J Chron Obstruct Pulmon Dis | pmid:27099485 |
| Noda AA et al. | First Report of the 23S rRNA Gene A2058G Point Mutation Associated With Macrolide Resistance in Treponema pallidum From Syphilis Patients in Cuba. | 2016 | Sex Transm Dis | pmid:27100771 |
| Kloepfer KM | Azithromycin may prevent severe respiratory-infection-induced wheezing. | 2016 | J. Pediatr. | pmid:27112084 |
| MUW researcher of the month Franz Ratzinger. | 2016 | Wien. Klin. Wochenschr. | pmid:27113348 | |
| Yelenich-Huss MJ et al. | Ozena in Immigrants of Differing Backgrounds. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27114295 |
| Zheng Z et al. | Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. | 2016 | J. Antibiot. | pmid:27118243 |
| Latif SA et al. | Azithromycin buccal patch in treatment of chronic periodontitis. | 2016 Mar-Apr | Indian J Pharmacol | pmid:27127325 |
| Barve A et al. | The effects of CYP3A4 induction and inhibition on the pharmacokinetics of alisporivir in humans. | 2015 | Clin Pharmacol Drug Dev | pmid:27128001 |
| Tous Romero F et al. | Acute Infection by Staphylococcus simulans in the Hand of a Man. | 2016 | JAMA Dermatol | pmid:27144675 |
| O'Beirne SL et al. | Trust Your Instincts. Surgical Lung Biopsy with Normal Chest Imaging in a 49-Year-Old Man with Progressive Dyspnea. | 2016 | Ann Am Thorac Soc | pmid:27144798 |
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| Horner PJ et al. | 2016 European guideline on the management of non-gonococcal urethritis. | 2016 | Int J STD AIDS | pmid:27147267 |
| Ramaiah B et al. | High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice. | 2016 | Daru | pmid:27150818 |
| Hanssens L et al. | The clinical benefits of long-term supplementation with omega-3 fatty acids in cystic fibrosis patients - A pilot study. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:27154364 |
| Oliveira GN et al. | Congenital dacryocystocoele with prenatal diagnosis. | 2016 | BMJ Case Rep | pmid:27166005 |
| Kong FY et al. | Higher organism load associated with failure of azithromycin to treat rectal chlamydia. | 2016 | Epidemiol. Infect. | pmid:27180823 |
| Morgan R et al. | Unusual cause of lymphangitis in a 2-year-old boy. | 2016 | BMJ Case Rep | pmid:27181743 |
| Fleming-Dutra KE et al. | Early Azithromycin Treatment to Prevent Severe Lower Respiratory Tract Illnesses in Children. | 2016 | JAMA | pmid:27187308 |
| Bacharier LB et al. | Early Azithromycin Treatment to Prevent Severe Lower Respiratory Tract Illnesses in Children--Reply. | 2016 | JAMA | pmid:27187309 |
| Ab Rahman N et al. | Antibiotic prescribing in public and private practice: a cross-sectional study in primary care clinics in Malaysia. | 2016 | BMC Infect. Dis. | pmid:27188538 |
| Keenan JD et al. | Nasopharyngeal Pneumococcal Serotypes Before and After Mass Azithromycin Distributions for Trachoma. | 2016 | J Pediatric Infect Dis Soc | pmid:27199475 |
| Phong NC et al. | In Vivo Efficacy and Tolerability of Artesunate-Azithromycin for the Treatment of Falciparum Malaria in Vietnam. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27215294 |
| Rosenthal PJ | Azithromycin for Malaria? | 2016 | Am. J. Trop. Med. Hyg. | pmid:27215296 |
| Itaqui SR et al. | In Vitro Synergism between Azithromycin or Terbinafine and Topical Antimicrobial Agents against Pythium insidiosum. | 2016 | Antimicrob. Agents Chemother. | pmid:27216049 |
| Das S et al. | Revisit of fluoroquinolone and azithromycin susceptibility breakpoints for Salmonella enterica serovar Typhi. | 2016 | J. Med. Microbiol. | pmid:27221661 |
| Haas AN et al. | Predictors of clinical outcomes after periodontal treatment of aggressive periodontitis: 12-month randomized trial. | 2016 | Braz Oral Res | pmid:27223128 |
| Liu Y et al. | Influence of Omega 3 and 6 Fatty Acids on Human Meibomian Gland Epithelial Cells. | 2016 | Cornea | pmid:27227397 |
| Yuan ZF et al. | Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with Mycoplasma pneumoniae infection. | 2016 | BMC Infect. Dis. | pmid:27230114 |
| Mertens TC et al. | Azithromycin differentially affects the IL-13-induced expression profile in human bronchial epithelial cells. | 2016 | Pulm Pharmacol Ther | pmid:27246785 |
| Zhou QT et al. | How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder? | 2016 | AAPS J | pmid:27255350 |
| Long SS | Optimizing antimicrobial therapy in children. | 2016 | J. Infect. | pmid:27263076 |
| Marks M | Yaws: towards the WHO eradication target. | 2016 | Trans. R. Soc. Trop. Med. Hyg. | pmid:27268712 |
| GarcÃa-Quintanilla M et al. | Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii. | 2016 | Antimicrob. Agents Chemother. | pmid:27270288 |
| El-Shitany NA and El-Desoky K | Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-β, and TNF-α Production and Inhibiting NF-κB and Caspase-3 Expression. | 2016 | Oxid Med Cell Longev | pmid:27274777 |
| Falay D et al. | Microbiological, clinical and molecular findings of non-typhoidal Salmonella bloodstream infections associated with malaria, Oriental Province, Democratic Republic of the Congo. | 2016 | BMC Infect. Dis. | pmid:27286886 |
| Akoglu G et al. | Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. | 2016 May-Jun | Indian J Pharmacol | pmid:27298507 |
| Belkacem A et al. | Molecular epidemiology and mechanisms of resistance of azithromycin-resistant Neisseria gonorrhoeae isolated in France during 2013-14. | 2016 | J. Antimicrob. Chemother. | pmid:27301565 |
| Shah SA et al. | Meibomian gland dysfunction: azithromycin and objective improvement in outcomes in posterior blepharitis. | 2016 | Clin. Experiment. Ophthalmol. | pmid:27314917 |
| Sacks HS | In older adults, macrolide antibiotics were not linked to increased risk for ventricular arrhythmia. | 2016 | Ann. Intern. Med. | pmid:27323264 |
| Weckmann M et al. | Treatment with rhDNase in patients with cystic fibrosis alters in-vitro CHIT-1 activity of isolated leucocytes. | 2016 | Clin. Exp. Immunol. | pmid:27324468 |
| Kimani J et al. | Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial. | 2016 | PLoS ONE | pmid:27326859 |
| Miyake H et al. | Meibomian Gland Dysfunction Model in Hairless Mice Fed a Special Diet With Limited Lipid Content. | 2016 | Invest. Ophthalmol. Vis. Sci. | pmid:27327582 |
| Gesink D et al. | Mycoplasma genitalium in Toronto, Ont: Estimates of prevalence and macrolide resistance. | 2016 | Can Fam Physician | pmid:27331225 |
| Fifer H et al. | Failure of Dual Antimicrobial Therapy in Treatment of Gonorrhea. | 2016 | N. Engl. J. Med. | pmid:27332921 |
| Zhou Y et al. | Azithromycin therapy during respiratory syncytial virus bronchiolitis: Upper airway microbiome alterations and subsequent recurrent wheeze. | 2016 | J. Allergy Clin. Immunol. | pmid:27339392 |
| Wang X et al. | Increased therapeutic efficacy of combination of azithromycin and ceftazidime on Pseudomonas aeruginosa biofilm in an animal model of ureteral stent infection. | 2016 | BMC Microbiol. | pmid:27341798 |
| Menzel M et al. | Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients. | 2016 | Sci Rep | pmid:27350308 |
| Narayanasamy DK et al. | Clinico - Laboratory Profile of Scrub Typhus - An Emerging Rickettsiosis in India. | 2016 | Indian J Pediatr | pmid:27352842 |
| Katanami Y et al. | Six Cases of Paratyphoid Fever Due to Salmonella Paratyphi A in Travelers Returning from Myanmar Between July 2014 and August 2015. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27352874 |
| Lockington D | Oral azithromycin and blepharitis: symptoms and signs improve, so where are the publications? | 2016 | Clin. Experiment. Ophthalmol. | pmid:27356302 |
| de Zwart L et al. | Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling. | 2016 | Clin. Pharmacol. Ther. | pmid:27367453 |
| Liu B et al. | Relationship between Community Drug Administration Strategy and Changes in Trachoma Prevalence, 2007 to 2013. | 2016 | PLoS Negl Trop Dis | pmid:27385309 |
| Malhotra S et al. | Prevalence of Trachoma in Car-Nicobar Island, India after Three Annual Rounds of Mass Drug Administration with Azithromycin. | 2016 | PLoS ONE | pmid:27391274 |
| Davido B et al. | Why should 1 gram of ceftriaxone monotherapy be considered as a therapeutic option in gonococcal sexually transmitted diseases? | 2016 | Clin. Microbiol. Infect. | pmid:27404364 |
| Wang A et al. | Effects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia. | 2016 | Sci Rep | pmid:27405358 |
| Horner P and Saunders J | Should azithromycin 1 g be abandoned as a treatment for bacterial STIs? The case for and against. | 2017 | Sex Transm Infect | pmid:27418572 |
| Chavada VD et al. | Surface plasmon resonance based selective and sensitive colorimetric determination of azithromycin using unmodified silver nanoparticles in pharmaceuticals and human plasma. | 2017 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:27419643 |
| Abdus-Salam RA et al. | A comparative study of azithromycin and sulphadoxine-pyrimethamine as prophylaxis against malaria in pregnancy. | Niger Postgrad Med J | pmid:27424614 | |
| Goh YS et al. | Neutralizing Antibodies against Plasmodium falciparum Associated with Successful Cure after Drug Therapy. | 2016 | PLoS ONE | pmid:27427762 |
| Jacobsson S et al. | WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014. | 2016 | J. Antimicrob. Chemother. | pmid:27432597 |
| Huang SW et al. | Azithromycin impairs TLR7 signaling in dendritic cells and improves the severity of imiquimod-induced psoriasis-like skin inflammation in mice. | 2016 | J. Dermatol. Sci. | pmid:27449383 |
| Zhao M et al. | Comparison of minocycline and azithromycin for the treatment of mild scrub typhus in northern China. | 2016 | Int. J. Antimicrob. Agents | pmid:27449540 |
| Kobbernagel HE et al. | Study protocol, rationale and recruitment in a European multi-centre randomized controlled trial to determine the efficacy and safety of azithromycin maintenance therapy for 6Â months in primary ciliary dyskinesia. | 2016 | BMC Pulm Med | pmid:27450411 |
| Zhu B et al. | High Resistance to Azithromycin in Clinical Samples from Patients with Sexually Transmitted Diseases in Guangxi Zhuang Autonomous Region, China. | 2016 | PLoS ONE | pmid:27467164 |
| Abeles SR et al. | Microbial diversity in individuals and their household contacts following typical antibiotic courses. | 2016 | Microbiome | pmid:27473422 |
| O'Farrell N | Control of gonorrhoea and chlamydia in the UK. | 2016 | Lancet | pmid:27477165 |
| Jeong BH et al. | Peak Plasma Concentration of Azithromycin and Treatment Responses in Mycobacterium avium Complex Lung Disease. | 2016 | Antimicrob. Agents Chemother. | pmid:27480854 |
| Yoshioka D et al. | Efficacy of β-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal Pneumonia. | 2016 | Antimicrob. Agents Chemother. | pmid:27480866 |
| Segal LN et al. | Randomised, double-blind, placebo-controlled trial with azithromycin selects for anti-inflammatory microbial metabolites in the emphysematous lung. | 2017 | Thorax | pmid:27486204 |
| O'Rourke VJ | Azithromycin as an adjunct to non-surgical periodontal therapy: a systematic review. | 2017 | Aust Dent J | pmid:27492140 |
| Samson C et al. | Long-term effects of azithromycin in patients with cystic fibrosis. | 2016 | Respir Med | pmid:27492507 |
| Björnelius E et al. | macrolide resistance in Stockholm, Sweden. | 2017 | Sex Transm Infect | pmid:27502694 |
| Dukers-Muijrers NH et al. | Design of the FemCure study: prospective multicentre study on the transmission of genital and extra-genital Chlamydia trachomatis infections in women receiving routine care. | 2016 | BMC Infect. Dis. | pmid:27502928 |
| Zhu XH et al. | Viral and Bacterial Etiology of Acute Diarrhea among Children under 5 Years of Age in Wuhan, China. | 2016 | Chin. Med. J. | pmid:27503019 |
| Cheng GS et al. | Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant. | 2016 | Ann Am Thorac Soc | pmid:27513368 |
| Xiridou M et al. | Cost-Effectiveness of Dual Antimicrobial Therapy for Gonococcal Infections Among Men Who Have Sex With Men in the Netherlands. | 2016 | Sex Transm Dis | pmid:27513379 |
| Molini BJ et al. | Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains. | 2016 | Sex Transm Dis | pmid:27513385 |
| Chatterjee S et al. | Azithromycin susceptibility among clinical isolates of Salmonella: Interfacing guidelines with routine practices. | 2016 Jul-Sep | Indian J Med Microbiol | pmid:27514976 |
| Espadas D et al. | Lack of effect of azithromycin on QT interval in children: a cohort study. | 2016 | Arch. Dis. Child. | pmid:27515186 |
| Akram FE et al. | A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27530257 |
| Mustapha NA et al. | Impact of different antibiotics on methane production using waste-activated sludge: mechanisms and microbial community dynamics. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27531514 |
| Committee Opinion No. 645 Summary: Dual Therapy for Gonococcal Infections. | 2016 | Obstet Gynecol | pmid:27548417 | |
| Committee Opinion No. 645: Dual Therapy for Gonococcal Infections. | 2016 | Obstet Gynecol | pmid:27548425 | |
| Marks M et al. | Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma. | 2016 | PLoS Negl Trop Dis | pmid:27551787 |
| Lemieux JE et al. | A global map of genetic diversity in Babesia microti reveals strong population structure and identifies variants associated with clinical relapse. | 2016 | Nat Microbiol | pmid:27572973 |
| Yadav H et al. | Azithromycin for the Treatment of Obliterative Bronchiolitis after Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis. | 2016 | Biol. Blood Marrow Transplant. | pmid:27575542 |
| Yasuda M et al. | Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility of azithromycin and increase in the failure of azithromycin therapy in male gonococcal urethritis in Sendai in 2015. | 2016 | J. Infect. Chemother. | pmid:27578029 |
| Purssell A et al. | Azithromycin and Doxycycline Attenuation of Acanthamoeba Virulence in a Human Corneal Tissue Model. | 2017 | J. Infect. Dis. | pmid:27578848 |
| Nair S et al. | WGS for surveillance of antimicrobial resistance: a pilot study to detect the prevalence and mechanism of resistance to azithromycin in a UK population of non-typhoidal Salmonella. | 2016 | J. Antimicrob. Chemother. | pmid:27585964 |