Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Harris JA et al. | Safety and efficacy of azithromycin in the treatment of community-acquired pneumonia in children. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802626 |
| Bremond-Gignac D et al. | Efficacy and safety of azithromycin 1.5% eye drops for purulent bacterial conjunctivitis in pediatric patients. | 2010 | Pediatr. Infect. Dis. J. | pmid:19935122 |
| Pichichero ME et al. | Azithromycin for the treatment of pertussis. | 2003 | Pediatr. Infect. Dis. J. | pmid:14515842 |
| Toltzis P et al. | Change in pneumococcal susceptibility to azithromycin during treatment for acute otitis media. | 2007 | Pediatr. Infect. Dis. J. | pmid:17596812 |
| Ferrarini A et al. | Henoch-Schönlein syndrome and pertussis. | 2007 | Pediatr. Infect. Dis. J. | pmid:17596820 |
| Wubbel L et al. | Etiology and treatment of community-acquired pneumonia in ambulatory children. | 1999 | Pediatr. Infect. Dis. J. | pmid:10048679 |
| Snelling PJ et al. | Rhabdomyolysis Complicating Typhoid Fever in A Child and Review of the Literature. | 2017 | Pediatr. Infect. Dis. J. | pmid:28430751 |
| Coles CL et al. | Mass distribution of azithromycin for trachoma control is associated with short-term reduction in risk of acute lower respiratory infection in young children. | 2012 | Pediatr. Infect. Dis. J. | pmid:22173140 |
| Pacifico L and Chiesa C | Efficacy of three-day azithromycin vs. ten-day penicillin V in the treatment of streptococcal pharyngitis. | 1997 | Pediatr. Infect. Dis. J. | pmid:9154566 |
| Banerjee R et al. | Azithromycin treatment of recurrent respiratory tract infections in children. | 2005 | Pediatr. Infect. Dis. J. | pmid:16282955 |
| Heiman KE et al. | Shigellosis with decreased susceptibility to azithromycin. | 2014 | Pediatr. Infect. Dis. J. | pmid:25361413 |
| Nightingale CH | Pharmacokinetics and pharmacodynamics of newer macrolides. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109156 |
| Block SL | Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109158 |
| Tarlow MJ et al. | Future indications for macrolides. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109159 |
| Shelby-James TM et al. | Impact of single dose azithromycin on group A streptococci in the upper respiratory tract and skin of Aboriginal children. | 2002 | Pediatr. Infect. Dis. J. | pmid:12150171 |
| Belvisi V et al. | Bartonella henselae infection presenting with ocular and hepatosplenic manifestations in an immunocompetent child. | 2012 | Pediatr. Infect. Dis. J. | pmid:22801097 |
| Yee CL et al. | Tendon or joint disorders in children after treatment with fluoroquinolones or azithromycin. | 2002 | Pediatr. Infect. Dis. J. | pmid:12182376 |
| Gordon EM and Blumer JL | Rationale for single and high dose treatment regimens with azithromycin. | 2004 | Pediatr. Infect. Dis. J. | pmid:14770072 |
| Meyer Sauteur PM et al. | Neuroinvasive Mycoplasma pneumoniae infection without intrathecal antibody response. | 2012 | Pediatr. Infect. Dis. J. | pmid:22760530 |
| Meloni G and Meloni T | Azithromycin vs. doxycycline for Mediterranean spotted fever. | 1996 | Pediatr. Infect. Dis. J. | pmid:8933556 |
| Arguedas A et al. | Single dose azithromycin for the treatment of uncomplicated otitis media. | 2004 | Pediatr. Infect. Dis. J. | pmid:14770073 |
| Jackson MA et al. | Breakthrough sepsis in macrolide-resistant pneumococcal infection. | 1996 | Pediatr. Infect. Dis. J. | pmid:8933560 |
| Arrieta A and Singh J | Management of recurrent and persistent acute otitis media: new options with familiar antibiotics. | 2004 | Pediatr. Infect. Dis. J. | pmid:14770074 |
| Cohen R | Defining the optimum treatment regimen for azithromycin in acute tonsillopharyngitis. | 2004 | Pediatr. Infect. Dis. J. | pmid:14770076 |
| Ruuskanen O | Safety and tolerability of azithromycin in pediatric infectious diseases: 2003 update. | 2004 | Pediatr. Infect. Dis. J. | pmid:14770077 |
| Klein JO and Schaad UB | [Use of azithromycin in the treatment of acute otitis media and tonsillopharyngitis: summary and conclusions. | 2004 | Pediatr. Infect. Dis. J. | pmid:14770078 |
| Raju M et al. | Atovaquone and azithromycin treatment for babesiosis in an infant. | 2007 | Pediatr. Infect. Dis. J. | pmid:17259886 |
| Morrison W | Infantile hypertrophic pyloric stenosis in infants treated with azithromycin. | 2007 | Pediatr. Infect. Dis. J. | pmid:17259889 |
| Dagan R et al. | Resistant organisms and otitis media. | 2005 | Pediatr. Infect. Dis. J. | pmid:16148862 |
| Marchisio P and Principi N | Single dose azithromycin for treatment of uncomplicated acute otitis media. | 2005 | Pediatr. Infect. Dis. J. | pmid:16148864 |
| Watson ME and Storch GA | Recurrent Mycoplasma pneumoniae infection in a human immunodeficiency virus-positive child. | 2008 | Pediatr. Infect. Dis. J. | pmid:18985833 |
| Gonzalez BE et al. | Azithromycin compared with beta-lactam antibiotic treatment failures in pneumococcal infections of children. | 2004 | Pediatr. Infect. Dis. J. | pmid:15131461 |
| Cohen R et al. | Comparison of two dosages of azithromycin for three days versus penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. | 2002 | Pediatr. Infect. Dis. J. | pmid:12075760 |
| Schaad UB et al. | Azithromycin versus penicillin V for treatment of acute group A streptococcal pharyngitis. | 2002 | Pediatr. Infect. Dis. J. | pmid:12075761 |
| Miron D et al. | Azithromycin as an alternative to nalidixic acid in the therapy of childhood shigellosis. | 2004 | Pediatr. Infect. Dis. J. | pmid:15071299 |
| Aderinboye O and Syed SS | Congenital babesiosis in a four-week-old female infant. | 2010 | Pediatr. Infect. Dis. J. | pmid:20118748 |
| Saegeman V et al. | Management of macrolide-resistant Mycoplasma pneumoniae infection. | 2012 | Pediatr. Infect. Dis. J. | pmid:22668803 |
| Minodier P et al. | Cutaneous leishmaniasis treated with azithromycin in a child. | 2008 | Pediatr. Infect. Dis. J. | pmid:18162948 |
| Arguedas A et al. | A randomized, multicenter, double blind, double dummy trial of single dose azithromycin versus high dose amoxicillin for treatment of uncomplicated acute otitis media. | 2005 | Pediatr. Infect. Dis. J. | pmid:15702045 |
| Jacobs RF et al. | Pharmacokinetics of intravenously administered azithromycin in pediatric patients. | 2005 | Pediatr. Infect. Dis. J. | pmid:15665708 |
| Powers JL et al. | Comparison of the palatability of the oral suspension of cefdinir vs. amoxicillin/clavulanate potassium, cefprozil and azithromycin in pediatric patients. | 2000 | Pediatr. Infect. Dis. J. | pmid:11144401 |
| Tramper-Stranders GA et al. | Maintenance azithromycin treatment in pediatric patients with cystic fibrosis: long-term outcomes related to macrolide resistance and pulmonary function. | 2007 | Pediatr. Infect. Dis. J. | pmid:17195698 |
| Toltzis P et al. | Comparative effects of single-dose ceftriaxone versus three oral antibiotic regimens on stool colonization by resistant bacilli in children. | 2007 | Pediatr. Infect. Dis. J. | pmid:17195701 |
| Esposito S et al. | Role of atypical bacteria and azithromycin therapy for children with recurrent respiratory tract infections. | 2005 | Pediatr. Infect. Dis. J. | pmid:15876944 |
| Gomperts BN and White LK | Gonococcal hand abscess. | 2000 | Pediatr. Infect. Dis. J. | pmid:10917235 |
| Glanternik JR et al. | A Cluster of Cases of Babesia microti Among Neonates Traced to a Single Unit of Donor Blood. | 2018 | Pediatr. Infect. Dis. J. | pmid:28945680 |
| Adegbola RA et al. | Effect of azithromycin on pharyngeal microflora. | 1995 | Pediatr. Infect. Dis. J. | pmid:7603826 |
| Jain SK et al. | Antimicrobial-resistant Shigella sonnei: limited antimicrobial treatment options for children and challenges of interpreting in vitro azithromycin susceptibility. | 2005 | Pediatr. Infect. Dis. J. | pmid:15933557 |
| Hoberman A et al. | Large dosage amoxicillin/clavulanate, compared with azithromycin, for the treatment of bacterial acute otitis media in children. | 2005 | Pediatr. Infect. Dis. J. | pmid:15933563 |
| Bowden FJ et al. | Donovanosis causing cervical lymphadenopathy in a five-month-old boy. | 2000 | Pediatr. Infect. Dis. J. | pmid:10694010 |
| Fleming-Dutra KE et al. | Variations in Antibiotic and Azithromycin Prescribing for Children by Geography and Specialty-United States, 2013. | 2018 | Pediatr. Infect. Dis. J. | pmid:28746259 |
| Dagan R et al. | Dynamics of pneumococcal nasopharyngeal colonization during the first days of antibiotic treatment in pediatric patients. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802628 |
| Bass JW et al. | Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655532 |
| Klein JO | History of macrolide use in pediatrics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109154 |
| Klein JO | Clarithromycin and azithromycin. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655546 |
| McCracken GH | Microbiologic activity of the newer macrolide antibiotics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109155 |
| Tarlow MJ | Macrolides in the management of streptococcal pharyngitis/tonsillitis. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109157 |
| Dagan R et al. | Early eradication of pathogens from middle ear fluid during antibiotic treatment of acute otitis media is associated with improved clinical outcome. | 1998 | Pediatr. Infect. Dis. J. | pmid:9779760 |
| Girgis N et al. | Azithromycin compared with rifampin for eradication of nasopharyngeal colonization by Neisseria meningitidis. | 1998 | Pediatr. Infect. Dis. J. | pmid:9779768 |
| Reed MD and Blumer JL | Azithromycin: a critical review of the first azilide antibiotic and its role in pediatric practice. | 1997 | Pediatr. Infect. Dis. J. | pmid:9384342 |
| Hammerschlag MR et al. | Treatment of neonatal chlamydial conjunctivitis with azithromycin. | 1998 | Pediatr. Infect. Dis. J. | pmid:9849993 |
| Arnež M and Ružić-Sabljić E | Azithromycin Is Equally Effective as Amoxicillin in Children with Solitary Erythema Migrans. | 2015 | Pediatr. Infect. Dis. J. | pmid:26186104 |
| Basualdo W and Arbo A | Randomized comparison of azithromycin versus cefixime for treatment of shigellosis in children. | 2003 | Pediatr. Infect. Dis. J. | pmid:12712971 |
| Soni N et al. | Recurrent acute interstitial nephritis induced by azithromycin. | 2004 | Pediatr. Infect. Dis. J. | pmid:15602202 |
| Schaad UB and Heynen G | Evaluation of the efficacy, safety and toleration of azithromycin vs. penicillin V in the treatment of acute streptococcal pharyngitis in children: results of a multicenter, open comparative study. The Swiss Tonsillopharyngitis Study Group. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878223 |
| McLinn S and Williams D | Incidence of antibiotic-resistant Streptococcus pneumoniae and beta-lactamase-positive Haemophilus influenzae in clinical isolates from patients with otitis media. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878239 |
| McCarty J | A multicenter, open label trial of azithromycin for the treatment of children with acute otitis media. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878240 |
| Aronovitz G | A multicenter, open label trial of azithromycin vs. amoxicillin/ clavulanate for the management of acute otitis media in children. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878241 |
| McLinn S | A multicenter, double blind comparison of azithromycin and amoxicillin/ clavulanate for the treatment of acute otitis media in children. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878242 |
| Khurana CM | A multicenter, randomized, open label comparison of azithromycin and amoxicillin/clavulanate in acute otitis media among children attending day care or school. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878243 |
| Powers JL | Properties of azithromycin that enhance the potential for compliance in children with upper respiratory tract infections. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878244 |
| Farooq O et al. | Azithromycin-induced agitation and choreoathetosis. | 2011 | Pediatr. Neurol. | pmid:21397177 |
| Weinberger M et al. | Diffuse panbronchiolitis in a 10-year-old boy. | 2015 | Pediatr. Pulmonol. | pmid:25824890 |
| Schultz KD and Oermann CM | Treatment of cast bronchitis with low-dose oral azithromycin. | 2003 | Pediatr. Pulmonol. | pmid:12526076 |
| Nguyen D et al. | Clinical response to azithromycin in cystic fibrosis correlates with in vitro effects on Pseudomonas aeruginosa phenotypes. | 2007 | Pediatr. Pulmonol. | pmid:17469154 |
| Kogan R et al. | Comparative randomized trial of azithromycin versus erythromycin and amoxicillin for treatment of community-acquired pneumonia in children. | 2003 | Pediatr. Pulmonol. | pmid:12526069 |
| Jubin V et al. | Risk factors for Aspergillus colonization and allergic bronchopulmonary aspergillosis in children with cystic fibrosis. | 2010 | Pediatr. Pulmonol. | pmid:20597074 |
| Ratjen F et al. | Response to letter. | 2015 | Pediatr. Pulmonol. | pmid:24700677 |
| Kneyber MC et al. | Azithromycin does not improve disease course in hospitalized infants with respiratory syncytial virus (RSV) lower respiratory tract disease: a randomized equivalence trial. | 2008 | Pediatr. Pulmonol. | pmid:18085694 |
| Zemanick ET et al. | Pulmonary exacerbations in cystic fibrosis with negative bacterial cultures. | 2010 | Pediatr. Pulmonol. | pmid:20503282 |
| Saiman L et al. | Open-label, follow-on study of azithromycin in pediatric patients with CF uninfected with Pseudomonas aeruginosa. | 2012 | Pediatr. Pulmonol. | pmid:22684984 |
| Wilms EB et al. | Azithromycin maintenance therapy in patients with cystic fibrosis: a dose advice based on a review of pharmacokinetics, efficacy, and side effects. | 2012 | Pediatr. Pulmonol. | pmid:22684985 |
| Willekens J et al. | How long should we maintain long-term azithromycin treatment in cystic fibrosis patients? | 2015 | Pediatr. Pulmonol. | pmid:24464958 |
| Luo Z et al. | Effects of prednisolone on refractory mycoplasma pneumoniae pneumonia in children. | 2014 | Pediatr. Pulmonol. | pmid:23401275 |
| Arıkan-Ayyıldız Z et al. | Survival of an infant with homozygous surfactant protein C (SFTPC) mutation. | 2014 | Pediatr. Pulmonol. | pmid:24347240 |
| ElMallah MK et al. | Plastic bronchitis: resolution after heart transplantation. | 2011 | Pediatr. Pulmonol. | pmid:21465672 |
| Ballard HO et al. | Use of azithromycin for the prevention of bronchopulmonary dysplasia in preterm infants: a randomized, double-blind, placebo controlled trial. | 2011 | Pediatr. Pulmonol. | pmid:20963840 |
| Aghai ZH et al. | Azithromycin suppresses activation of nuclear factor-kappa B and synthesis of pro-inflammatory cytokines in tracheal aspirate cells from premature infants. | 2007 | Pediatr. Res. | pmid:17667842 |
| Walls SA et al. | Antibiotic prophylaxis improves Ureaplasma-associated lung disease in suckling mice. | 2009 | Pediatr. Res. | pmid:19390479 |
| Londhe VA et al. | Hyperoxia impairs alveolar formation and induces senescence through decreased histone deacetylase activity and up-regulation of p21 in neonatal mouse lung. | 2011 | Pediatr. Res. | pmid:21270677 |
| Weisman LE et al. | Appropriate antibiotic therapy improves Ureaplasma sepsis outcome in the neonatal mouse. | 2012 | Pediatr. Res. | pmid:22907617 |
| Eberly MD et al. | Azithromycin in early infancy and pyloric stenosis. | 2015 | Pediatrics | pmid:25687145 |
| Oluwalana C et al. | Azithromycin in Labor Lowers Clinical Infections in Mothers and Newborns: A Double-Blind Trial. | 2017 | Pediatrics | pmid:28130432 |
| Gerber JS and Zaoutis TE | Azithromycin Prophylaxis for Laboring Mothers. | 2017 | Pediatrics | pmid:28130431 |
| Cogen JD et al. | Characterization of Inpatient Cystic Fibrosis Pulmonary Exacerbations. | 2017 | Pediatrics | pmid:28126911 |
| Langley JM et al. | Azithromycin is as effective as and better tolerated than erythromycin estolate for the treatment of pertussis. | 2004 | Pediatrics | pmid:15231980 |
| Cohen DA et al. | A school-based Chlamydia control program using DNA amplification technology. | 1998 | Pediatrics | pmid:9417165 |
| Amer A and Fischer H | Azithromycin does not cure pityriasis rosea. | 2006 | Pediatrics | pmid:16651327 |
| Clavier A and Hupert J | Azithromycin for pityriasis. | 2006 | Pediatrics | pmid:17079605 |
| Fox JW et al. | Recurrent expressive aphasia as a presentation of cat-scratch encephalopathy. | 2007 | Pediatrics | pmid:17332191 |