Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wirnsberger GH et al. | Effect of antibiotic treatment with azithromycin on cyclosporine A-induced gingival hyperplasia among renal transplant recipients. | 1998 | Transplant. Proc. | pmid:9723411 |
| Bayoumi AM and Redelmeier DA | Preventing Mycobacterium avium complex in patients who are using protease inhibitors: a cost-effectiveness analysis. | 1998 | AIDS | pmid:9727572 |
| Moyle GJ et al. | Once weekly azithromycin as prophylaxis against recurrence of non-tuberculous mycobacterial infections in HIV-1-positive individuals. | 1998 | AIDS | pmid:9727581 |
| Smith NH et al. | Combination drug therapy for cryptosporidiosis in AIDS. | 1998 | J. Infect. Dis. | pmid:9728569 |
| Alder JD et al. | Dynamics of clarithromycin and azithromycin efficacies against experimental Haemophilus influenzae pulmonary infection. | 1998 | Antimicrob. Agents Chemother. | pmid:9736568 |
| Yeo AE et al. | Indirect inhibition by antibiotics of nucleotide and deoxynucleotide biosynthesis in Plasmodium falciparum. | 1998 | Southeast Asian J. Trop. Med. Public Health | pmid:9740262 |
| Mainardi JL et al. | Cat scratch disease due to Bartonella henselae serotype Marseille (Swiss cat) in a seronegative patient. | 1998 | J. Clin. Microbiol. | pmid:9742017 |
| Apseloff G et al. | Comparison of azithromycin and clarithromycin in their interactions with rifabutin in healthy volunteers. | 1998 | J Clin Pharmacol | pmid:9753212 |
| Greenblatt DJ et al. | Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. | 1998 | Clin. Pharmacol. Ther. | pmid:9757151 |
| Pontani D et al. | Susceptibility of European respiratory tract isolates to trovafloxacin, ciprofloxacin, clarithromycin, azithromycin and ampicillin. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9758284 |
| Dagan R et al. | Early eradication of pathogens from middle ear fluid during antibiotic treatment of acute otitis media is associated with improved clinical outcome. | 1998 | Pediatr. Infect. Dis. J. | pmid:9779760 |
| Girgis N et al. | Azithromycin compared with rifampin for eradication of nasopharyngeal colonization by Neisseria meningitidis. | 1998 | Pediatr. Infect. Dis. J. | pmid:9779768 |
| Shih CM and Wang CC | Ability of azithromycin in combination with quinine for the elimination of babesial infection in humans. | 1998 | Am. J. Trop. Med. Hyg. | pmid:9790419 |
| Davis TM | Adverse effects of antimalarial prophylactic drugs: an important consideration in the risk-benefit equation. | 1998 | Ann Pharmacother | pmid:9793605 |
| Sánchez F et al. | [Treatment of pneumonia caused by Legionella with azithromycin]. | 1998 | Rev Esp Quimioter | pmid:9795300 |
| Pankuch GA et al. | In vitro selection of resistance to four beta-lactams and azithromycin in Streptococcus pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9797225 |
| Harris JA et al. | Safety and efficacy of azithromycin in the treatment of community-acquired pneumonia in children. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802626 |
| Dagan R et al. | Dynamics of pneumococcal nasopharyngeal colonization during the first days of antibiotic treatment in pediatric patients. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802628 |
| Johnson DM et al. | Antimicrobial interactions of trovafloxacin and extended-spectrum cephalosporins or azithromycin tested against clinical isolates of Pseudomonas aeruginosa and Stenotrophomonas maltophilia. | 1998 | J. Antimicrob. Chemother. | pmid:9818765 |
| Champney WS and Burdine R | Macrolide antibiotic inhibition of translation and 50S ribosomal subunit assembly in methicillin-resistant Staphylococcus aureus cells. | 1998 | Microb. Drug Resist. | pmid:9818968 |
| Bauriedel G et al. | Azithromycin, Chlamydia pneumoniae, and intimal thickening. | 1998 | Circulation | pmid:9826328 |
| Ward TT et al. | Randomized, open-label trial of azithromycin plus ethambutol vs. clarithromycin plus ethambutol as therapy for Mycobacterium avium complex bacteremia in patients with human immunodeficiency virus infection. Veterans Affairs HIV Research Consortium. | 1998 | Clin. Infect. Dis. | pmid:9827282 |
| Gascón A et al. | Cryptosporidiosis in a haemodialysis patient with depressed CD4+ T cell count: successful treatment with azithromycin. | 1998 | Nephrol. Dial. Transplant. | pmid:9829506 |
| Shafran SD | Prevention and treatment of disseminated Mycobacterium avium complex infection in human immunodeficiency virus-infected individuals. | 1998 Jul-Sep | Int. J. Infect. Dis. | pmid:9831675 |
| Karcioglu ZA et al. | Pharmacokinetics of azithromycinin rabbit lacrimal glands and conjunctiv a. | 1999 | Ophthalmic Res. | pmid:9831822 |
| Sackoff J et al. | Prophylaxis for opportunistic infections among HIV-infected patients receiving medical care. | 1998 | J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. | pmid:9833748 |
| Berry V et al. | Bacteriological efficacies of three macrolides compared with those of amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae. | 1998 | Antimicrob. Agents Chemother. | pmid:9835514 |
| Hogan PA and Sheehan DJ | Macrolide susceptibility and beta-lactamase production among haemophilus influenzae isolates in the United States, 1996-1997. | 1998 | Antimicrob. Agents Chemother. | pmid:9835536 |
| Bonoan JT et al. | Life-threatening babesiosis in an asplenic patient treated with exchange transfusion, azithromycin, and atovaquone. | 1998 Nov-Dec | Heart Lung | pmid:9835673 |
| Hammerschlag MR et al. | Treatment of neonatal chlamydial conjunctivitis with azithromycin. | 1998 | Pediatr. Infect. Dis. J. | pmid:9849993 |
| Raines DA et al. | Simultaneous high-performance liquid chromatography analysis of azithromycin and two of its metabolites in human tears and plasma. | 1998 | Ther Drug Monit | pmid:9853988 |
| Tapsall JW et al. | Failure of azithromycin therapy in gonorrhea and discorrelation with laboratory test parameters. | 1998 | Sex Transm Dis | pmid:9858344 |
| Schuster FL and Visvesvara GS | Efficacy of novel antimicrobials against clinical isolates of opportunistic amebas. | 1998 Nov-Dec | J. Eukaryot. Microbiol. | pmid:9864851 |
| Dohmen W and Seelis RE | The role of azithromycin in the treatment of Helicobacter pylori infection - a retrospective report. | 1998 Jul-Aug | Infection | pmid:9867486 |
| Choi EK and Pai H | Azithromycin therapy for scrub typhus during pregnancy. | 1998 | Clin. Infect. Dis. | pmid:9868680 |
| Amsden GW et al. | Pharmacokinetics in serum and leukocyte exposures of oral azithromycin, 1,500 milligrams, given over a 3- or 5-day period in healthy subjects. | 1999 | Antimicrob. Agents Chemother. | pmid:9869584 |
| Tabbara KF et al. | Ocular levels of azithromycin. | 1998 | Arch. Ophthalmol. | pmid:9869792 |
| Denis A and Agouridas C | Synthesis of 6-O-methyl-azithromycin and its ketolide analogue via Beckmann rearrangement of 9(E)-6-O-methyl-erythromycin oxime. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9873555 |
| Gruber F et al. | Azithromycin compared with minocycline in the treatment of acne comedonica and papulo-pustulosa. | 1998 | J Chemother | pmid:9876055 |
| Ghirga G et al. | Inefficacy of a 3-day course of azithromycin in preventing acute rheumatic fever after group A streptococcal infection (scarlet fever) in an 8-year-old child. | 1999 | J. Pediatr. | pmid:9880464 |
| Chey WD et al. | Low- versus high-dose azithromycin triple therapy for Helicobacter pylori infection. | 1998 | Aliment. Pharmacol. Ther. | pmid:9882036 |
| Trevisani L et al. | Evaluation of a new ultrashort triple therapy for Helicobacter pylori disease. | 1998 | Aliment. Pharmacol. Ther. | pmid:9882037 |
| Gruber F et al. | Treatment of confluent and reticulated papillomatosis with azithromycin. | 1998 | Clin. Exp. Dermatol. | pmid:9894368 |
| Négrel AD and Mariotti SP | WHO alliance for the global elimination of blinding trachoma and the potential use of azithromycin. | 1998 | Int. J. Antimicrob. Agents | pmid:9916898 |
| Lacy MK et al. | Comparison of bactericidal activity after multidose administration of clarithromycin, azithromycin, and ceruroxime axetil against Streptococcus pneumoniae. | 1998 | Int. J. Antimicrob. Agents | pmid:9916901 |
| Fera MT et al. | Bactericidal activity of lansoprazole and three macrolides against Helicobacter pylori strains tested by the time-kill kinetic method. | 1998 | Int. J. Antimicrob. Agents | pmid:9916902 |
| Jakob-Sölder B et al. | Treatment of pediatric patients with acute group A beta-hemolytic streptococcal tonsillopharyngitis. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9923529 |
| Rothova A et al. | Azithromycin for ocular toxoplasmosis. | 1998 | Br J Ophthalmol | pmid:9924338 |
| Adriaenssen CF | Comparison of the efficacy, safety and tolerability of azithromycin and co-amoxiclav in the treatment of acute periapical abscesses. | 1998 Oct-Nov | J. Int. Med. Res. | pmid:9924711 |
| Oliva S et al. | Successful treatment of widely disseminated acanthamoebiasis. | 1999 | South. Med. J. | pmid:9932828 |