Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Dry Eye Syndromes D015352 10 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Corneal Edema D015715 3 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Helicobacter Infections D016481 21 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Wynn RF et al. Azithromycin for cerebral toxoplasmosis in AIDS. 1993 Lancet pmid:8093526
Bailey RL et al. Randomised controlled trial of single-dose azithromycin in treatment of trachoma. 1993 Lancet pmid:8102427
Nahata MC et al. Pharmacokinetics of azithromycin in pediatric patients after oral administration of multiple doses of suspension. 1993 Antimicrob. Agents Chemother. pmid:8383944
Vaara M Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. 1993 Antimicrob. Agents Chemother. pmid:8383945
Cameron DJ Effectiveness of early Lyme disease treatment. 1993 Am. J. Med. pmid:8388627
Melski JW et al. Primary and secondary erythema migrans in central Wisconsin. 1993 Arch Dermatol pmid:8389536
Amacher DE et al. Preclinical toxicology studies with azithromycin: genetic toxicology evaluation. 1993 Mutat. Res. pmid:7685497
Lefèvre JC et al. In vitro evaluation of activities of azithromycin, clarithromycin and sparfloxacin against Chlamydia trachomatis. 1993 Pathol. Biol. pmid:8233628
Agacfidan A et al. In vitro activity of azithromycin (CP-62,993) against Chlamydia trachomatis and Chlamydia pneumoniae. 1993 Antimicrob. Agents Chemother. pmid:8239579
Tomazic J et al. In vivo administration of azithromycin affects lymphocyte activity in vitro. 1993 Antimicrob. Agents Chemother. pmid:8239585
Cantin L and Chamberland S In vitro evaluation of the activities of azithromycin alone and combined with pyrimethamine against Toxoplasma gondii. 1993 Antimicrob. Agents Chemother. pmid:8239619
Meyer AP et al. Uptake of azithromycin by human monocytes and enhanced intracellular antibacterial activity against Staphylococcus aureus. 1993 Antimicrob. Agents Chemother. pmid:8285612
Lalak NJ and Morris DL Azithromycin clinical pharmacokinetics. 1993 Clin Pharmacokinet pmid:8287632
Saverino D et al. Plasmid loss from gram-negative bacteria exposed to subinhibitory concentrations of beta-lactam drugs and azithromycin. 1993 New Microbiol. pmid:8264424
Pajukanta R In vitro antimicrobial susceptibility of Porphyromonas gingivalis to azithromycin, a novel macrolide. 1993 Oral Microbiol. Immunol. pmid:8265209
Gage TW New drugs from 1991-1992. 1993 Tex Dent J pmid:8273018
Holdcroft C Two new macrolide antibiotics: clarithromycin and azithromycin. 1993 Nurse Pract pmid:8380492
Spangler SK and Appelbaum PC Oxyrase, a method which avoids CO2 in the incubation atmosphere for anaerobic susceptibility testing of antibiotics affected by CO2. 1993 J. Clin. Microbiol. pmid:8381817
de Górgolas Hernández-Mora M et al. [Therapeutic approaches to cryptosporidiosis. A review of the literature]. 1993 Rev Clin Esp pmid:8259458
Gingras BA and Jensen JB Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. 1993 Am. J. Trop. Med. Hyg. pmid:8394660