Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Otitis Media, Suppurative D010035 4 associated lipids
Serum Sickness D012713 7 associated lipids
Bites, Human D001734 2 associated lipids
Rickettsia Infections D012282 5 associated lipids
Pharyngeal Diseases D010608 4 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

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What genes are associated with Azithramycine?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Authors Title Published Journal PubMed Link
Dias R and Caniça M Emergence of invasive erythromycin-resistant Streptococcus pneumoniae strains in Portugal: contribution and phylogenetic relatedness of serotype 14. 2004 J. Antimicrob. Chemother. pmid:15531597
Tobin JM et al. Which treatment for genital tract Chlamydia trachomatis infection? 2004 Int J STD AIDS pmid:15537459
Basilion EV et al. Simplification and improvement of height-based azithromycin treatment for paediatric trachoma. 2005 Trans. R. Soc. Trop. Med. Hyg. pmid:15550255
Ioannidis J and Wilkinson D HIV: prevention of opportunistic infections. 2003 Clin Evid pmid:15555123
Mann J et al. Gonorrhea treatment guidelines in Canada: 2004 update. 2004 CMAJ pmid:15557584
Caronzolo D et al. Glucocorticoids increase in vitro and in vivo activities of antibiotics against Chlamydophila pneumoniae. 2004 Antimicrob. Agents Chemother. pmid:15561871
Carter G et al. A subinhibitory concentration of clarithromycin inhibits Mycobacterium avium biofilm formation. 2004 Antimicrob. Agents Chemother. pmid:15561879
Hyodo E et al. Effect of azithromycin therapy on coronary circulation in patients with coronary artery disease. 2004 Am. J. Cardiol. pmid:15566918
Khamitov RF et al. [Significance of antibacterial therapy of Chlamydophila pneumoniae infection in patients with bronchial asthma]. 2004 Ter. Arkh. pmid:15575487
Gillis RJ and Iglewski BH Azithromycin retards Pseudomonas aeruginosa biofilm formation. 2004 J. Clin. Microbiol. pmid:15583321
Amsden GW Anti-inflammatory effects of macrolides--an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions? 2005 J. Antimicrob. Chemother. pmid:15590715
Le Normand Y et al. [An example of simulation for a better understanding of PK/PD relationship of antibiotics]. 2004 Pathol. Biol. pmid:15596309
Ranque S et al. In vitro activity of azithromycin and dirithromycin against axenic Entamoeba histolytica. 2004 Eur. J. Clin. Microbiol. Infect. Dis. pmid:15599659
Soni N et al. Recurrent acute interstitial nephritis induced by azithromycin. 2004 Pediatr. Infect. Dis. J. pmid:15602202
Zervos M et al. Comparative efficacies and tolerabilities of intravenous azithromycin plus ceftriaxone and intravenous levofloxacin with step-down oral therapy for hospitalized patients with moderate to severe community-acquired pneumonia. 2004 Treat Respir Med pmid:15606222
Wilms E et al. Quantitative determination of azithromycin in plasma, blood and isolated neutrophils by liquid chromatography using pre-column derivatization with 9-fluorenylmethyloxycarbonyl-chloride and fluorescence detection. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15607705
Mumcu G et al. Clinical and immunological effects of azithromycin in Behçet's disease. 2005 J. Oral Pathol. Med. pmid:15610401
Weiss K et al. Clinical characteristics at initial presentation and impact of dual therapy on the outcome of bacteremic Streptococcus pneumoniae pneumonia in adults. 2004 Nov-Dec Can. Respir. J. pmid:15611810
Kiddugavu MG et al. Effectiveness of syphilis treatment using azithromycin and/or benzathine penicillin in Rakai, Uganda. 2005 Sex Transm Dis pmid:15614114
Hughes WT et al. Comparison of atovaquone and azithromycin with trimethoprim-sulfamethoxazole for the prevention of serious bacterial infections in children with HIV infection. 2005 Clin. Infect. Dis. pmid:15614703
Tokgöz B et al. Effects of azithromycin on cyclosporine-induced gingival hyperplasia in renal transplant patients. 2004 Transplant. Proc. pmid:15621128
West ES et al. Mass treatment and the effect on the load of Chlamydia trachomatis infection in a trachoma-hyperendemic community. 2005 Invest. Ophthalmol. Vis. Sci. pmid:15623758
Conti CR Antibiotics for coronary disease: it's time to move on. 2004 Clin Cardiol pmid:15628106
Mueller M et al. Toll-like receptors 2 and 4 do not contribute to clearance of Chlamydophila pneumoniae in mice, but are necessary for the release of monokines. 2004 Immunobiology pmid:15638128
Alexander ND et al. An index of community ocular Chlamydia trachomatis load for control of trachoma. 2005 Trans. R. Soc. Trop. Med. Hyg. pmid:15653119
Barker PM et al. Effect of macrolides on in vivo ion transport across cystic fibrosis nasal epithelium. 2005 Am. J. Respir. Crit. Care Med. pmid:15657462
Pino Rivero V et al. [Facial palsy caused by otitis media with effusion in a 9-year old child]. 2004 An Otorrinolaringol Ibero Am pmid:15663088
Jacobs RF et al. Pharmacokinetics of intravenously administered azithromycin in pediatric patients. 2005 Pediatr. Infect. Dis. J. pmid:15665708
Verma A and Dhawan A Re: Trial of metronidazole vs. azithromycin for treatment of cyclosporine-induced gingival overgrowth. 2005 Pediatr Transplant pmid:15667627
Altunaiji S et al. Antibiotics for whooping cough (pertussis). 2005 Cochrane Database Syst Rev pmid:15674946
Klochkov OI et al. [The use of azithromycin in prophylaxis of respiratory infections occurred in the organized collectives, clinical sequelae]. 2004 Voen Med Zh pmid:15675752
Verleden GM et al. Is it bronchiolitis obliterans syndrome or is it chronic rejection: a reappraisal? 2005 Eur. Respir. J. pmid:15684284
Kyebambe P Incomplete Reiter's arthritis in a 23 year old nursing mother. 2004 Afr Health Sci pmid:15687073
Prahalad S et al. Fatal acute fibrinous and organizing pneumonia in a child with juvenile dermatomyositis. 2005 J. Pediatr. pmid:15689928
Schalock PC and Dinulos JG Mycoplasma pneumoniae-induced Stevens-Johnson syndrome without skin lesions: fact or fiction? 2005 J. Am. Acad. Dermatol. pmid:15692479
Preheim LC et al. Effect of cirrhosis on antibiotic efficacy in a rat model of pneumococcal pneumonia. 2005 Diagn. Microbiol. Infect. Dis. pmid:15698715
Arguedas A et al. A randomized, multicenter, double blind, double dummy trial of single dose azithromycin versus high dose amoxicillin for treatment of uncomplicated acute otitis media. 2005 Pediatr. Infect. Dis. J. pmid:15702045
McCormack JG and Bell SC Has the time come to prescribe azithromycin in cystic fibrosis patients? 2005 Intern Med J pmid:15705133
Waters LJ et al. Efficacy of azithromycin 1 g single dose in the management of uncomplicated gonorrhoea. 2005 Int J STD AIDS pmid:15705283
O'Mahony C Blindingly obvious! 2005 Int J STD AIDS pmid:15705287
Carter JD et al. Antimicrobial treatment for Chlamydia induced reactive arthritis. 2005 Ann. Rheum. Dis. pmid:15708913
Golden MR et al. Effect of expedited treatment of sex partners on recurrent or persistent gonorrhea or chlamydial infection. 2005 N. Engl. J. Med. pmid:15716561
Cárceles CM et al. Pharmacokinetics of azithromycin after intravenous and intramuscular administration to goats. 2005 J. Vet. Pharmacol. Ther. pmid:15720515
Srinivasan R and Yeo TH Are newer macrolides effective in eradicating carriage of pertussis? 2005 Arch. Dis. Child. pmid:15723933
Verhoeven V et al. Implementation of a pilot programme for screening for chlamydial infection in general practice. 2004 Eur J Gen Pract pmid:15724126
Swanson RN et al. Once-daily azithromycin for 3 days compared with clarithromycin for 10 days for acute exacerbation of chronic bronchitis: a multicenter, double-blind, randomized study. 2005 Treat Respir Med pmid:15725048
Berry V et al. Comparative bacteriological efficacy of pharmacokinetically enhanced amoxicillin-clavulanate against Streptococcus pneumoniae with elevated amoxicillin MICs and Haemophilus influenzae. 2005 Antimicrob. Agents Chemother. pmid:15728883
Lafortune M et al. Proliferative enteritis associated with Lawsonia intracellularis in a Japanese macaque (Macaca fuscata). 2004 J. Zoo Wildl. Med. pmid:15732600
Yang YZ [Death of a case caused by anaphylaxis to azithromycin]. 2004 Zhonghua Er Ke Za Zhi pmid:15733367
Kadota J et al. Antibiotic-induced apoptosis in human activated peripheral lymphocytes. 2005 Int. J. Antimicrob. Agents pmid:15737515
Bryant DH Obliterative bronchiolitis in haematopoietic stem cell transplantation: can it be treated? 2005 Eur. Respir. J. pmid:15738280
Khalid M et al. Azithromycin in bronchiolitis obliterans complicating bone marrow transplantation: a preliminary study. 2005 Eur. Respir. J. pmid:15738293
Vainas T et al. Secondary prevention of atherosclerosis through chlamydia pneumoniae eradication (SPACE Trial): a randomised clinical trial in patients with peripheral arterial disease. 2005 Eur J Vasc Endovasc Surg pmid:15749042
Hansen CR et al. Long-term azitromycin treatment of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection; an observational cohort study. 2005 J. Cyst. Fibros. pmid:15752679
Janahi IA et al. Rapidly progressive lung disease in a patient with cystic fibrosis on long-term azithromycin: possible role of mycoplasma infection. 2005 J. Cyst. Fibros. pmid:15752685
Brandén E et al. Intermittent azithromycin treatment for respiratory symptoms in patients with chronic Chlamydia pneumoniae infection. 2004 Scand. J. Infect. Dis. pmid:15764166
Lescano SA et al. [Evaluation of the efficacy of azithromycin and pyrimethamine, for treatment of experimental infection of mice with Toxoplasma gondii cystogenic strain]. 2004 Nov-Dec Rev. Soc. Bras. Med. Trop. pmid:15765594
Halpern MT et al. Meta-analysis of bacterial resistance to macrolides. 2005 J. Antimicrob. Chemother. pmid:15772147
Guven MA et al. The demographic and behavioural profile of women with cervicitis infected with Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum and the comparison of two medical regimens. 2005 Arch. Gynecol. Obstet. pmid:15778862
García Vázquez E et al. Lower mortality among patients with community-acquired pneumonia treated with a macrolide plus a beta-lactam agent versus a beta-lactam agent alone. 2005 Eur. J. Clin. Microbiol. Infect. Dis. pmid:15782278
Kotloff KL et al. Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A streptococcus vaccine. 2005 Infect. Immun. pmid:15784582
Imamura Y et al. Azithromycin exhibits bactericidal effects on Pseudomonas aeruginosa through interaction with the outer membrane. 2005 Antimicrob. Agents Chemother. pmid:15793115
Skrepnek GH et al. An economic and outcomes assessment of first-line monotherapy in the treatment of community-acquired pneumonia within managed care. 2005 Curr Med Res Opin pmid:15801997
Kastelik JA et al. Azithromycin in cystic fibrosis. 2005 Eur. Respir. J. pmid:15802355
Tabbara KF et al. Azithromycin prophylaxis and treatment of murine toxoplasmosis. 2005 Saudi Med J pmid:15806206
Kus S et al. Comparison of efficacy of azithromycin vs. doxycycline in the treatment of acne vulgaris. 2005 Clin. Exp. Dermatol. pmid:15807672
Yoshida K et al. Macrolides with promotive activity of monocyte to macrophage differentiation. 2005 J. Antibiot. pmid:15813186
Cymbala AA et al. The disease-modifying effects of twice-weekly oral azithromycin in patients with bronchiectasis. 2005 Treat Respir Med pmid:15813663
Young F Sexually transmitted infections. Genital chlamydia: practical management in primary care. 2005 J Fam Health Care pmid:15819362
Snider LA et al. Antibiotic prophylaxis with azithromycin or penicillin for childhood-onset neuropsychiatric disorders. 2005 Biol. Psychiatry pmid:15820236
Burton MJ et al. Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study. 2005 Apr 9-15 Lancet pmid:15823382
Berquand A et al. Interaction of the macrolide antibiotic azithromycin with lipid bilayers: effect on membrane organization, fluidity, and permeability. 2005 Pharm. Res. pmid:15835753
Dunne MW et al. A multicenter study of azithromycin, alone and in combination with chloroquine, for the treatment of acute uncomplicated Plasmodium falciparum malaria in India. 2005 J. Infect. Dis. pmid:15838784
Grayston JT et al. Azithromycin for the secondary prevention of coronary events. 2005 N. Engl. J. Med. pmid:15843666
Anderson JL Infection, antibiotics, and atherothrombosis--end of the road or new beginnings? 2005 N. Engl. J. Med. pmid:15843674
Blessing E et al. A 6 week course of azithromycin treatment has no beneficial effect on atherosclerotic lesion development in apolipoprotein E-deficient mice chronically infected with Chlamydia pneumoniae. 2005 J. Antimicrob. Chemother. pmid:15845780
Iur'ev SIu et al. [Azithromycin levels in the chorion tissue within the first three months of the pregnancy term]. 2004 Antibiot. Khimioter. pmid:15850052
Tu D et al. Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. 2005 Cell pmid:15851032
Reveneau N et al. Bactericidal activity of first-choice antibiotics against gamma interferon-induced persistent infection of human epithelial cells by Chlamydia trachomatis. 2005 Antimicrob. Agents Chemother. pmid:15855497
Mascarenhas P et al. Clinical response of azithromycin as an adjunct to non-surgical periodontal therapy in smokers. 2005 J. Periodontol. pmid:15857078
Blanco M et al. Application of NIR spectroscopy in polymorphic analysis: study of pseudo-polymorphs stability. 2005 J Pharm Sci pmid:15858852
Kim DD et al. Neonatal group B streptococcus sepsis after negative screen in a patient taking oral antibiotics. 2005 Obstet Gynecol pmid:15863602
Low N Chlamydia (uncomplicated, genital). 2004 Clin Evid pmid:15865780
Zhang JX et al. [Resistant analysis and cultivation results of 3 160 blood specimen]. 2005 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:15871208
Goodchild JH Oral triazolam sedation in implant dentistry. 2005 J Oral Implantol pmid:15871531
Zar HJ Neonatal chlamydial infections: prevention and treatment. 2005 Paediatr Drugs pmid:15871630
Bahrami G et al. High performance liquid chromatographic determination of azithromycin in serum using fluorescence detection and its application in human pharmacokinetic studies. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15876560
Zou CC and Liang L Multiple hypoechoic lesions in spleen and Mycoplasma pneumoniae infection. 2005 Indian Pediatr pmid:15876602
Esposito S et al. Role of atypical bacteria and azithromycin therapy for children with recurrent respiratory tract infections. 2005 Pediatr. Infect. Dis. J. pmid:15876944
Cazzola M et al. Treatment of acute exacerbation of severe-to-very severe COPD with azithromycin in patients vaccinated against Streptococcus pneumoniae. 2005 Respir Med pmid:15878482
Sommer A Systemic antibiotics for communitywide trachoma control. 2005 Arch. Ophthalmol. pmid:15883291
Babic Z et al. Increased activity of Pgp multidrug transporter in patients with Helicobacter pylori infection. 2005 World J. Gastroenterol. pmid:15884110
Mahgoub A et al. Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats. 2005 Toxicol. Appl. Pharmacol. pmid:15885263
Bouchillon SK et al. Impact of carbon dioxide on the susceptibility of key respiratory tract pathogens to telithromycin and azithromycin. 2005 J. Antimicrob. Chemother. pmid:15890718
Dandekar PK et al. Assessment of the efficacy of telithromycin simulating human exposures against S. pneumoniae with ribosomal mutations in a murine pneumonia model. 2005 Int. J. Antimicrob. Agents pmid:15894464
Casey JR and Pichichero ME Higher dosages of azithromycin are more effective in treatment of group A streptococcal tonsillopharyngitis. 2005 Clin. Infect. Dis. pmid:15909262
Mori T et al. Tacrolimus-azithromycin interaction in a recipient of allogeneic bone marrow transplantation. 2005 Transpl. Int. pmid:15910307
Levy SB et al. The misuse of antibiotics. 2004 Med Ethics (Burlingt Mass) pmid:15915579
Bosnar M et al. Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin. 2005 Antimicrob. Agents Chemother. pmid:15917536
Fairgrieve WT et al. Accumulation and clearance of orally administered erythromycin and its derivative, azithromycin, in juvenile fall chinook salmon Oncorhynchus tshawytscha. 2005 Dis. Aquat. Org. pmid:15918472