Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Bronchial Hyperreactivity D016535 15 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Díaz Sánchez M et al. [New medications: azithromycin]. 1993 Jul-Sep Rev Med Univ Navarra pmid:8134755
Odugbemi T et al. Single oral dose of azithromycin for therapy of susceptible sexually transmitted diseases: a multicenter open evaluation. 1993 Jul-Sep West Afr J Med pmid:8312208
Minguez F et al. In vitro killing kinetics and postantibiotic effect of josamycin and other macrolides on several bacteria. 1993 May-Jun Chemotherapy pmid:8389685
Weber K et al. Azithromycin versus penicillin V for the treatment of early Lyme borreliosis. 1993 Nov-Dec Infection pmid:8132365
Scaglione F et al. A new model examining intracellular and extracellular activity of amoxicillin, azithromycin, and clarithromycin in infected cells. 1993 Nov-Dec Chemotherapy pmid:8222870
Braga PC and Piatti G Interference by subinhibitory concentrations of azithromycin with the mechanism of bacterial adhesion to human epithelial cells. 1993 Nov-Dec Chemotherapy pmid:8222872
Goldman MP and Longworth DL The role of azithromycin and clarithromycin in clinical practice. 1993 Sep-Oct Cleve Clin J Med pmid:8403355
Jones RN et al. Validation of NCCLS macrolide (azithromycin, clarithromycin, and erythromycin) interpretive criteria for Haemophilus influenzae tested with the Haemophilus test medium. National Committee for Clinical Laboratory Standards. 1994 Diagn. Microbiol. Infect. Dis. pmid:7924221
Wallace MR et al. Azithromycin and typhoid. 1994 Lancet pmid:7911192
Pacor ML et al. [Safety of azithromycin in patients allergic to penicillin and cephalosporin]. 1994 Clin Ter pmid:8001336
Wolinsky E Mycobacterium avium strains resistant to clarithromycin and azithromycin. 1994 Antimicrob. Agents Chemother. pmid:8031406
Trevisi P et al. Toxic pustuloderma associated with azithromycin. 1994 Clin. Exp. Dermatol. pmid:8033402
Katelaris PH et al. Activity of metronidazole, azithromycin and three benzimidazoles on Giardia lamblia growth and attachment to a human intestinal cell line. 1994 Aliment. Pharmacol. Ther. pmid:8038350
Steven N et al. Corticosteroid therapy for AIDS patients with Mycobacterium avium-intracellulare infection. 1994 AIDS pmid:8011231
Chiarini F et al. Chlamydia trachomatis genitourinary infections: laboratory diagnosis and therapeutic aspects. Evaluation of in vitro and in vivo effectiveness of azithromycin. 1994 J Chemother pmid:7830100
[Newly approved specialty drugs in Austria and new knowledge about currently available specialty drugs. Zithromax capsules, dried syrup]. 1994 Wien. Klin. Wochenschr. pmid:7975673
Bush MR and Rosa C Azithromycin and erythromycin in the treatment of cervical chlamydial infection during pregnancy. 1994 Obstet Gynecol pmid:8008325
Godofsky EW Treatment of presumed cerebral toxoplasmosis with azithromycin. 1994 N. Engl. J. Med. pmid:8302335
Kelsey JJ et al. Presence of azithromycin breast milk concentrations: a case report. 1994 Am. J. Obstet. Gynecol. pmid:8178871
Rapp RP et al. New macrolide antibiotics: usefulness in infections caused by mycobacteria other than Mycobacterium tuberculosis. 1994 Ann Pharmacother pmid:7849341