Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Bartonella Infections D001474 3 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Dry Socket D004368 3 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Furunculosis D005667 2 associated lipids
Elephantiasis D004604 2 associated lipids
Lymphangitis D008205 4 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Herpes Genitalis D006558 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Fonck K et al. A randomized, placebo-controlled trial of monthly azithromycin prophylaxis to prevent sexually transmitted infections and HIV-1 in Kenyan sex workers: study design and baseline findings. 2000 Int J STD AIDS pmid:11138916
Schilling F and Wagner AD [Azithromycin: an anti-inflammatory effect in chronic recurrent multifocal osteomyelitis? A preliminary report]. 2000 Z Rheumatol pmid:11142932
Powers JL et al. Comparison of the palatability of the oral suspension of cefdinir vs. amoxicillin/clavulanate potassium, cefprozil and azithromycin in pediatric patients. 2000 Pediatr. Infect. Dis. J. pmid:11144401
Vallejo C et al. Resolution of cyclosporine-induced gingival hyperplasia resistant to azithromycin by switching to tacrolimus. 2001 Haematologica pmid:11146586
Amsden GW and Gray CL Serum and WBC pharmacokinetics of 1500 mg of azithromycin when given either as a single dose or over a 3 day period in healthy volunteers. 2001 J. Antimicrob. Chemother. pmid:11152432
Giacometti A et al. Activity of buforin II alone and in combination with azithromycin and minocycline against Cryptosporidium parvum in cell culture. 2001 J. Antimicrob. Chemother. pmid:11152438
Skerk V et al. Duration of clinical symptoms in female patients with acute urethral syndrome caused by Ureaplasma urealyticum treated with azithromycin or doxycycline. 2000 J Chemother pmid:11154040
Gieffers J et al. Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic treatment. 2001 Circulation pmid:11157684
Putnam SD et al. Pharyngeal colonization prevalence rates for Streptococcus pyogenes and Streptococcus pneumoniae in a respiratory chemoprophylaxis intervention study using azithromycin. 2000 Clin. Microbiol. Infect. pmid:11168029
Simsir A et al. Rhodococcus equi and cytomegalovirus pneumonia in a renal transplant patient: diagnosis by fine-needle aspiration biopsy. 2001 Diagn. Cytopathol. pmid:11169894
Solera J et al. Azithromycin and gentamicin therapy for the treatment of humans with brucellosis. 2001 Clin. Infect. Dis. pmid:11170962
Gerber MA and Tanz RR New approaches to the treatment of group A streptococcal pharyngitis. 2001 Curr. Opin. Pediatr. pmid:11176244
Conrad DA Treatment of cat-scratch disease. 2001 Curr. Opin. Pediatr. pmid:11176245
From the Centers for Disease Control and Prevention. Fluoroquinolone resistance in Neisseria gonorrhoeae, Hawaii, 1999, and decreased susceptibility to azithromycin in N. gonorrhoeae, Missouri, 1999. 2000 JAMA pmid:11183745
West S The red eye. 2000 N. Engl. J. Med. pmid:11184764
McNabb J et al. Comparison of azithromycin leukocyte disposition in healthy volunteers and volunteers with AIDS. 2000 Int. J. Antimicrob. Agents pmid:11185411
Amsden GW et al. A study of the pharmacokinetics of azithromycin and nelfinavir when coadministered in healthy volunteers. 2000 J Clin Pharmacol pmid:11185676
Mamikoglu B and Mamikoglu O Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. 2001 Ann. Otol. Rhinol. Laryngol. pmid:11201801
Khera M Azithromycin. 2000 Conn Med pmid:11210327
Amsden G et al. Lack of an effect of azithromycin on the disposition of zidovudine and dideoxyinosine in HIV-infected patients. 2001 J Clin Pharmacol pmid:11210404