| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tuberculosis, Pulmonary | D014397 | 18 associated lipids |
| Peptic Ulcer | D010437 | 19 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Malaria, Falciparum | D016778 | 22 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bala M et al. | Trends of resistance to antimicrobials recommended currently and in the past for management of gonorrhea in the Apex STD center in India and comparison of antimicrobial resistance profile between 2002-2006 and 2007-2012. | 2015 | Sex Transm Dis | pmid:25763675 |
| Laopaiboon M et al. | Azithromycin for acute lower respiratory tract infections. | 2015 | Cochrane Database Syst Rev | pmid:25749735 |
| Hicks LA et al. | US outpatient antibiotic prescribing variation according to geography, patient population, and provider specialty in 2011. | 2015 | Clin. Infect. Dis. | pmid:25747410 |
| Walsh MS et al. | Prevalence of Chlamydia trachomatis infection in Samoan women aged 18 to 29 and assessment of possible risk factors: a community-based study. | 2015 | Trans. R. Soc. Trop. Med. Hyg. | pmid:25732755 |
| Hamasuna R et al. | The second nationwide surveillance of the antimicrobial susceptibility of Neisseria gonorrhoeae from male urethritis in Japan, 2012-2013. | 2015 | J. Infect. Chemother. | pmid:25727286 |
| Gershengorn HB et al. | The association of antibiotic treatment regimen and hospital mortality in patients hospitalized with Legionella pneumonia. | 2015 | Clin. Infect. Dis. | pmid:25722195 |
| Min KW et al. | Education and imaging. Gastrointestinal: a case of histologically confirmed scrub typhus gastritis. | 2015 | J. Gastroenterol. Hepatol. | pmid:25707787 |
| Wessels MR et al. | Case records of the Massachusetts General Hospital. Case 6-2015. A 16-year-old boy with coughing spells. | 2015 | N. Engl. J. Med. | pmid:25693017 |
| Denlinger CE | Matrix metalloproteinases and bronchiolitis obliterans: Wrapping the enigma in a riddle. | 2015 | J. Thorac. Cardiovasc. Surg. | pmid:25618413 |
| Principi N et al. | Azithromycin use in patients with cystic fibrosis. | 2015 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:25686729 |
| Khosropour CM et al. | Efficacy of standard therapies against Ureaplasma species and persistence among men with non-gonococcal urethritis enrolled in a randomised controlled trial. | 2015 | Sex Transm Infect | pmid:25616607 |
| Liu Y et al. | Can tetracycline antibiotics duplicate the ability of azithromycin to stimulate human meibomian gland epithelial cell differentiation? | 2015 | Cornea | pmid:25611398 |
| Chen M et al. | Azithromycin attenuates cigarette smoke extract-induced oxidative stress injury in human alveolar epithelial cells. | 2015 | Mol Med Rep | pmid:25607112 |
| Sutton AL et al. | Perinatal pharmacokinetics of azithromycin for cesarean prophylaxis. | 2015 | Am. J. Obstet. Gynecol. | pmid:25595580 |
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| Unger HW et al. | Sulphadoxine-pyrimethamine plus azithromycin for the prevention of low birthweight in Papua New Guinea: a randomised controlled trial. | 2015 | BMC Med | pmid:25591391 |
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| Nonaka L et al. | Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. | 2015 | Lett. Appl. Microbiol. | pmid:25765542 |
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| Hodge S et al. | Increased CD8 T-cell granzyme B in COPD is suppressed by treatment with low-dose azithromycin. | 2015 | Respirology | pmid:25308201 |
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| Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
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| Aucamp M et al. | Amorphous azithromycin with improved aqueous solubility and intestinal membrane permeability. | 2015 | Drug Dev Ind Pharm | pmid:24980913 |
| Martinez MA et al. | Clinical and histologic features of azithromycin-induced liver injury. | 2015 | Clin. Gastroenterol. Hepatol. | pmid:25111234 |
| Cabeza J et al. | Feasibility of Chlamydia trachomatis screening and treatment in pregnant women in Lima, Peru: a prospective study in two large urban hospitals. | 2015 | Sex Transm Infect | pmid:25107711 |
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| Woodruff AE et al. | Azithromycin-Induced, Biopsy-Proven Acute Interstitial Nephritis in an Adult Successfully Treated with Low-Dose Corticosteroids. | 2015 | Pharmacotherapy | pmid:26598102 |
| Jensen EA et al. | Evidence-Based Pharmacologic Therapies for Prevention of Bronchopulmonary Dysplasia: Application of the Grading of Recommendations Assessment, Development, and Evaluation Methodology. | 2015 | Clin Perinatol | pmid:26593077 |
| Fan WG et al. | Male Paraurethral Duct Infection and Subsequent Paraurethral Duct Dilation. | 2015 | Chin. Med. J. | pmid:26608997 |
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| Hemmige V et al. | Recurrent skin and soft tissue infections in HIV-infected patients during a 5-year period: incidence and risk factors in a retrospective cohort study. | 2015 | BMC Infect. Dis. | pmid:26503616 |
| Su XH et al. | Multidrug-Resistant Neisseria gonorrhoeae Isolates from Nanjing, China, Are Sensitive to Killing by a Novel DNA Gyrase Inhibitor, ETX0914 (AZD0914). | 2015 | Antimicrob. Agents Chemother. | pmid:26482313 |
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| Jesus FP et al. | In Vitro and In Vivo Antimicrobial Activities of Minocycline in Combination with Azithromycin, Clarithromycin, or Tigecycline against Pythium insidiosum. | 2015 | Antimicrob. Agents Chemother. | pmid:26459895 |
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| Falk L et al. | Time to eradication of Mycoplasma genitalium after antibiotic treatment in men and women. | 2015 | J. Antimicrob. Chemother. | pmid:26283670 |
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| Fonseca DC et al. | Clinical and Microbiologic Evaluation of Scaling and Root Planing per Quadrant and One-Stage Full-Mouth Disinfection Associated With Azithromycin or Chlorhexidine: A Clinical Randomized Controlled Trial. | 2015 | J. Periodontol. | pmid:26252751 |
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| West SK et al. | Risk of Infection with Chlamydia trachomatis from Migrants to Communities Undergoing Mass Drug Administration for Trachoma Control. | 2015 | Ophthalmic Epidemiol | pmid:26158574 |
| Gebresillasie S et al. | Inter-Rater Agreement between Trachoma Graders: Comparison of Grades Given in Field Conditions versus Grades from Photographic Review. | 2015 | Ophthalmic Epidemiol | pmid:26158573 |
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| Jo KW et al. | The efficacy of prophylactic azithromycin on bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation. | 2015 | Int. J. Hematol. | pmid:26121954 |
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| Qin YH et al. | Transdermal application of azithromycin-amlodipine-heparin gel enhances survival of infected random ischaemic flap. | 2015 | J Plast Surg Hand Surg | pmid:26083309 |
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| Buset SL et al. | Non-surgical periodontal therapy supplemented with systemically administered azithromycin: a systematic review of RCTs. | 2015 | Clin Oral Investig | pmid:26063646 |
| Yin SM et al. | Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. | 2015 | J. Clin. Immunol. | pmid:26048260 |
| Craig AP et al. | Is it time to switch to doxycycline from azithromycin for treating genital chlamydial infections in women? Modelling the impact of autoinoculation from the gastrointestinal tract to the genital tract. | 2015 | BMC Infect. Dis. | pmid:25925662 |
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| Cusini M | Therapy for Gonococcal and Non-gonococcal Genital Infections is a Major Problem for Clinicians. | 2015 | Acta Derm. Venereol. | pmid:25917593 |
| Harding-Esch E et al. | Costs of testing for ocular Chlamydia trachomatis infection compared to mass drug administration for trachoma in the Gambia: application of results from the PRET study. | 2015 | PLoS Negl Trop Dis | pmid:25901349 |
| Escalante MG et al. | Comparison of Azithromycin and Amoxicillin Before Dental Implant Placement: An Exploratory Study of Bioavailability and Resolution of Postoperative Inflammation. | 2015 | J. Periodontol. | pmid:26252749 |
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| Barve A et al. | The effects of CYP3A4 induction and inhibition on the pharmacokinetics of alisporivir in humans. | 2015 | Clin Pharmacol Drug Dev | pmid:27128001 |
| Chandra R et al. | Comparison of azithromycin plus chloroquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in children in Africa: a randomized, open-label study. | 2015 | Malar. J. | pmid:25881046 |
| Gomi K et al. | Full-mouth scaling and root planing combined with azithromycin to treat peri-implantitis. | 2015 | Aust Dent J | pmid:25439282 |
| Schroeck JL et al. | Factors associated with antibiotic misuse in outpatient treatment for upper respiratory tract infections. | 2015 | Antimicrob. Agents Chemother. | pmid:25870064 |
| Zhi D et al. | The enhancement of cardiac toxicity by concomitant administration of Berberine and macrolides. | 2015 | Eur J Pharm Sci | pmid:25976224 |
| Verleden GM et al. | Current views on chronic rejection after lung transplantation. | 2015 | Transpl. Int. | pmid:25857869 |
| Singh AE et al. | Gonorrhea Treatment Failures With Oral and Injectable Expanded Spectrum Cephalosporin Monotherapy vs Dual Therapy at 4 Canadian Sexually Transmitted Infection Clinics, 2010-2013. | 2015 | Sex Transm Dis | pmid:25970311 |
| Waites KB et al. | In vitro antibacterial activity of AZD0914 against human Mycoplasmas and Ureaplasmas. | 2015 | Antimicrob. Agents Chemother. | pmid:25824220 |
| Unemo M et al. | Five-day Azithromycin Treatment Regimen for Mycoplasma genitalium Infection Also Effectively Eradicates Chlamydia trachomatis. | 2015 | Acta Derm. Venereol. | pmid:25823977 |
| Nakamura M et al. | Cat-scratch disease presenting as a solitary splenic abscess in an elderly man. | 2015 | BMJ Case Rep | pmid:25804947 |
| Phelan VV et al. | Mass Spectrometry Analysis of Pseudomonas aeruginosa Treated with Azithromycin. | 2015 | J. Am. Soc. Mass Spectrom. | pmid:25801585 |
| Jimenez V et al. | Mass drug administration for trachoma: how long is not long enough? | 2015 | PLoS Negl Trop Dis | pmid:25799168 |
| Kitsiouli E et al. | Effect of azithromycin on the LPS-induced production and secretion of phospholipase A2 in lung cells. | 2015 | Biochim. Biophys. Acta | pmid:25791017 |
| Prohl A et al. | Enrofloxacin and macrolides alone or in combination with rifampicin as antimicrobial treatment in a bovine model of acute Chlamydia psittaci infection. | 2015 | PLoS ONE | pmid:25768665 |