| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tuberculosis, Pulmonary | D014397 | 18 associated lipids |
| Peptic Ulcer | D010437 | 19 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Gastrointestinal Diseases | D005767 | 20 associated lipids |
| Heart Defects, Congenital | D006330 | 20 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Vomiting | D014839 | 21 associated lipids |
| Helicobacter Infections | D016481 | 21 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lu ZK et al. | Cardiac risks associated with antibiotics: azithromycin and levofloxacin. | 2015 | Expert Opin Drug Saf | pmid:25494485 |
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| Keenan JD et al. | Evidence for clonal expansion after antibiotic selection pressure: pneumococcal multilocus sequence types before and after mass azithromycin treatments. | 2015 | J. Infect. Dis. | pmid:25293366 |
| Young PM et al. | Multi-breath dry powder inhaler for delivery of cohesive powders in the treatment of bronchiectasis. | 2015 | Drug Dev Ind Pharm | pmid:24811055 |
| Willekens J et al. | How long should we maintain long-term azithromycin treatment in cystic fibrosis patients? | 2015 | Pediatr. Pulmonol. | pmid:24464958 |
| Galvidis I et al. | Group determination of 14-membered macrolide antibiotics and azithromycin using antibodies against common epitopes. | 2015 | Anal. Biochem. | pmid:25256165 |
| Méndez Abad P et al. | Idiopathic plastic bronchitis as an uncommon cause of massive pulmonary atelectasis. | 2015 | Arch. Bronconeumol. | pmid:24495947 |
| ACOG Committee Opinion No. 645: Dual Therapy for Gonococcal Infections. | 2015 | Obstet Gynecol | pmid:26488526 | |
| ACOG Committee Opinion No. 645 Summary: Dual Therapy for Gonococcal Infections. | 2015 | Obstet Gynecol | pmid:26488518 | |
| Babics A and Roussellier P | Gardnerella vaginalis: An overlooked pathogen in male patients? | 2015 | Med Mal Infect | pmid:26472061 |
| See CW et al. | The Effect of Mass Azithromycin Distribution on Childhood Mortality: Beliefs and Estimates of Efficacy. | 2015 | Am. J. Trop. Med. Hyg. | pmid:26392160 |
| Winters N et al. | Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment. | 2015 | Eur. Respir. J. | pmid:26381514 |
| Lau A et al. | The Efficacy of Azithromycin for the Treatment of Genital Mycoplasma genitalium: A Systematic Review and Meta-analysis. | 2015 | Clin. Infect. Dis. | pmid:26240201 |
| Goldstein LH et al. | Azithromycin is not associated with QT prolongation in hospitalized patients with community-acquired pneumonia. | 2015 | Pharmacoepidemiol Drug Saf | pmid:26238864 |
| Lahra MM | Australian Gonococcal Surveillance Programme annual report, 2013. | 2015 | Commun Dis Intell Q Rep | pmid:26063087 |
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| Beyda RM et al. | Azithromycin efficacy in the treatment of Chlamydia trachomatis among detained youth. | 2014 | Sex Transm Dis | pmid:25211253 |
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| Schachterle SE et al. | Short-term malaria reduction by single-dose azithromycin during mass drug administration for trachoma, Tanzania. | 2014 | Emerging Infect. Dis. | pmid:24865642 |
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| Phillips-Campbell R et al. | Induction of the Chlamydia muridarum stress/persistence response increases azithromycin treatment failure in a murine model of infection. | 2014 | Antimicrob. Agents Chemother. | pmid:24342653 |
| Jang MO et al. | Outcome of intravenous azithromycin therapy in patients with complicated scrub typhus compared with that of doxycycline therapy using propensity-matched analysis. | 2014 | Antimicrob. Agents Chemother. | pmid:24366734 |
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