Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Pelvic Pain D017699 7 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Furcation Defects D017823 1 associated lipids
T-Lymphocytopenia, Idiopathic CD4-Positive D018344 1 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

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What genes are associated with Azithramycine?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Authors Title Published Journal PubMed Link
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Aktan B et al. Effect of macrolide antibiotics on nitric oxide synthase and xanthine oxidase activities, and malondialdehyde level in erythrocyte of the guinea pigs with experimental otitis media with effusion. 2003 Nov-Dec Pol J Pharmacol pmid:14730107
Khandekarf R and Mohammed AJ Outcome of azithromycin treatment of active trachoma in Omani school children. 2003 Sep-Nov East. Mediterr. Health J. pmid:16450533
Wyrick PB and Knight ST Pre-exposure of infected human endometrial epithelial cells to penicillin in vitro renders Chlamydia trachomatis refractory to azithromycin. 2004 J. Antimicrob. Chemother. pmid:15163653
Frenck RW et al. Short-course azithromycin for the treatment of uncomplicated typhoid fever in children and adolescents. 2004 Clin. Infect. Dis. pmid:15034826
Smelov V et al. Azithromycin treatment follow-up: antibacterial susceptibility of Chlamydia trachomatis in patients with chronic prostatitis. 2004 Int. J. Antimicrob. Agents pmid:15037332
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Antibiotics ineffective for prevention of recurrent MI. 2004 J Fam Pract pmid:15251088
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Parry CM The treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever in Viet Nam. 2004 Trans. R. Soc. Trop. Med. Hyg. pmid:15138078
Paik JW et al. Inhibition of cyclosporin A-induced gingival overgrowth by azithromycin through phagocytosis: an in vivo and in vitro study. 2004 J. Periodontol. pmid:15088875
Guchev IA et al. Two regimens of azithromycin prophylaxis against community-acquired respiratory and skin/soft-tissue infections among military trainees. 2004 Clin. Infect. Dis. pmid:15095213
Miron D et al. Azithromycin as an alternative to nalidixic acid in the therapy of childhood shigellosis. 2004 Pediatr. Infect. Dis. J. pmid:15071299
Palcevski G et al. Antibiotic use profile at paediatric clinics in two transitional countries. 2004 Pharmacoepidemiol Drug Saf pmid:15072118
Gross M et al. Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor. 2004 J. Antimicrob. Chemother. pmid:14963065
Gandhi R et al. Pharmacokinetic evaluation of an azithromycin controlled release dosage form in healthy human volunteers: a single dose study. 2004 Int J Pharm pmid:14726116
Pino Rivero V et al. [Facial palsy caused by otitis media with effusion in a 9-year old child]. 2004 An Otorrinolaringol Ibero Am pmid:15663088
Fernandez-Obregon A Oral use of azithromycin for the treatment of acne rosacea. 2004 Arch Dermatol pmid:15096385
Dias R and Caniça M Emergence of invasive erythromycin-resistant Streptococcus pneumoniae strains in Portugal: contribution and phylogenetic relatedness of serotype 14. 2004 J. Antimicrob. Chemother. pmid:15531597
Tobin JM et al. Which treatment for genital tract Chlamydia trachomatis infection? 2004 Int J STD AIDS pmid:15537459
Iur'ev SIu et al. [Azithromycin levels in the chorion tissue within the first three months of the pregnancy term]. 2004 Antibiot. Khimioter. pmid:15850052
Brandén E et al. Intermittent azithromycin treatment for respiratory symptoms in patients with chronic Chlamydia pneumoniae infection. 2004 Scand. J. Infect. Dis. pmid:15764166
Carter G et al. A subinhibitory concentration of clarithromycin inhibits Mycobacterium avium biofilm formation. 2004 Antimicrob. Agents Chemother. pmid:15561879
Soni N et al. Recurrent acute interstitial nephritis induced by azithromycin. 2004 Pediatr. Infect. Dis. J. pmid:15602202
Zervos M et al. Comparative efficacies and tolerabilities of intravenous azithromycin plus ceftriaxone and intravenous levofloxacin with step-down oral therapy for hospitalized patients with moderate to severe community-acquired pneumonia. 2004 Treat Respir Med pmid:15606222
Jones S et al. The tip of the iceberg: opportunistic screening for Chlamydia trachomatis in asymptomatic patients attending a young people's health clinic reveals a high prevalence--a pilot study. 2004 Sex Health pmid:16334993
Gregory AR et al. Ophthalmomyiasis caused by the sheep bot fly Oestrus ovis in northern Iraq. 2004 Optom Vis Sci pmid:15300116
McHugh RC et al. A topical azithromycin preparation for the treatment of acne vulgaris and rosacea. 2004 J Dermatolog Treat pmid:15370397
Gattringer R et al. Antimicrobial susceptibility and macrolide resistance genes in Streptococcus pyogenes collected in Austria and Hungary. 2004 Int. J. Antimicrob. Agents pmid:15325435