Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Pericoronitis D010497 2 associated lipids
Tuberculosis, Urogenital D014401 2 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Abdominal Abscess D018784 2 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hoarseness D006685 2 associated lipids
Scrub Typhus D012612 3 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Frontal Sinusitis D015522 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Horner PJ and Martin DH Mycoplasma genitalium Infection in Men. 2017 J. Infect. Dis. pmid:28838074
Bradshaw CS et al. New Horizons in Mycoplasma genitalium Treatment. 2017 J. Infect. Dis. pmid:28838073
Paul P et al. Capillary electrophoresis with capacitively coupled contactless conductivity detection method development and validation for the determination of azithromycin, clarithromycin, and clindamycin. 2017 J Sep Sci pmid:28683179
Gaydos CA Mycoplasma genitalium: Accurate Diagnosis Is Necessary for Adequate Treatment. 2017 J. Infect. Dis. pmid:28838072
Volgers C et al. Budesonide, fluticasone propionate, and azithromycin do not modulate the membrane vesicle release by THP-1 macrophages and respiratory pathogens during macrophage infection. 2017 Inflammopharmacology pmid:28528362
Ribeiro M et al. Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells. 2017 Exp. Parasitol. pmid:28803905
Stieger N et al. Solution-mediated crystallization of amorphous azithromycin. 2017 Pharmazie pmid:29441902
Feng X and Liu J A combination of irsogladine maleate and azithromycin exhibits addictive protective effects in LPS-induced human gingival epithelial cells. 2017 Pharmazie pmid:29441859
Wiesenfeld HC Screening for Chlamydia trachomatis Infections in Women. 2017 N. Engl. J. Med. pmid:28225683
Shmarina G et al. Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression. 2017 Int. Arch. Allergy Immunol. pmid:28219060
Ramappa M et al. Successful Medical Management of Presumptive Pythium insidiosum Keratitis. 2017 Cornea pmid:28207431
González-Beiras C et al. Yaws Osteoperiostitis Treated with Single-Dose Azithromycin. 2017 Am. J. Trop. Med. Hyg. pmid:28193743
Saiz JC and Martín-Acebes MA Reply to Iannetta et al., "Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells". 2017 Antimicrob. Agents Chemother. pmid:28839084
Iannetta M et al. Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells. 2017 Antimicrob. Agents Chemother. pmid:28839081
Hallström H et al. Open flap debridement of peri-implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial. 2017 J. Clin. Periodontol. pmid:28836279
Papp JR et al. Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA. 2017 Emerging Infect. Dis. pmid:28418303
Liu Y et al. Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. 2017 Life Sci. pmid:27916734
Vandooren J et al. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. 2017 PLoS ONE pmid:28369077
Valdés SO et al. Cardiac Arrest in Pediatric Patients Receiving Azithromycin. 2017 J. Pediatr. pmid:27912925
Bojang E et al. Short-term increase in prevalence of nasopharyngeal carriage of macrolide-resistant Staphylococcus aureus following mass drug administration with azithromycin for trachoma control. 2017 BMC Microbiol. pmid:28351345
Kong FY et al. Pharmacokinetics of a single 1g dose of azithromycin in rectal tissue in men. 2017 PLoS ONE pmid:28350806
Bornstein M et al. Factors Associated With Primary Care Physician Knowledge of the Recommended Regimen for Treating Gonorrhea. 2017 Sex Transm Dis pmid:27898574
Agarwal E et al. Locally Delivered 0.5% Azithromycin as an Adjunct to Non-Surgical Treatment in Patients With Chronic Periodontitis With Type 2 Diabetes: A Randomized Controlled Clinical Trial. 2017 J. Periodontol. pmid:22655911
Murphy TK et al. A Double-Blind Randomized Placebo-Controlled Pilot Study of Azithromycin in Youth with Acute-Onset Obsessive-Compulsive Disorder. 2017 J Child Adolesc Psychopharmacol pmid:28358599
Eyre DW et al. WGS to predict antibiotic MICs for Neisseria gonorrhoeae. 2017 J. Antimicrob. Chemother. pmid:28333355
Shan LS et al. Effects of methylprednisolone or immunoglobulin when added to standard treatment with intravenous azithromycin for refractory Mycoplasma pneumoniae pneumonia in children. 2017 World J Pediatr pmid:28130749
Daimee UA et al. A 77-year-old man with fever and night sweats. 2017 Eur. J. Intern. Med. pmid:27765389
Purssell A et al. Azithromycin and Doxycycline Attenuation of Acanthamoeba Virulence in a Human Corneal Tissue Model. 2017 J. Infect. Dis. pmid:27578848
Lusk MJ et al. Cervicitis: a prospective observational study of empiric azithromycin treatment in women with cervicitis and non-specific cervicitis. 2017 Int J STD AIDS pmid:26792283
Marks M and Mabey D Single-dose azithromycin to treat latent yaws. 2017 Lancet Glob Health pmid:29107622
Mitjà O et al. Effectiveness of single-dose azithromycin to treat latent yaws: a longitudinal comparative cohort study. 2017 Lancet Glob Health pmid:29107621
Terkelsen D et al. Multidrug-resistant infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. 2017 Euro Surveill. pmid:29067905
Halhal B et al. Pertussis Outbreak Among Soldiers During Basic Training: The Need for Updated Protocols. 2017 Mil Med pmid:28291499
Çelik Payçu DG and Büyükbaba Boral Ö [Effects of azithromycin and Chlorella vulgaris treatment on certain cytokine values and NK cell activity in an acute murine toxoplasmosis model]. 2017 Mikrobiyol Bul pmid:28283010
Garcia-Vidal C et al. Levofloxacin versus azithromycin for treating legionella pneumonia: a propensity score analysis. 2017 Clin. Microbiol. Infect. pmid:28267637
Salman S et al. Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling. 2017 Antimicrob. Agents Chemother. pmid:28242669
Diniz LM et al. Bacillary angiomatosis with bone invasion. 2016 Nov-Dec An Bras Dermatol pmid:28099606
Akoglu G et al. Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. 2016 May-Jun Indian J Pharmacol pmid:27298507
Latif SA et al. Azithromycin buccal patch in treatment of chronic periodontitis. 2016 Mar-Apr Indian J Pharmacol pmid:27127325
Oliveira IS et al. Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. 2016 Mar-Apr Braz J Otorhinolaryngol pmid:26601998
Chatterjee S et al. Azithromycin susceptibility among clinical isolates of Salmonella: Interfacing guidelines with routine practices. 2016 Jul-Sep Indian J Med Microbiol pmid:27514976
Hazra A Author Reply. 2016 Jan-Feb Indian J Pharmacol pmid:26997735
Das S and Mohanty M Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. 2016 Jan-Feb Indian J Pharmacol pmid:26997734
Das A et al. Azithromycin induced bullous fixed drug eruption. 2016 Jan-Feb Indian J Pharmacol pmid:26997729
Paul SP et al. Spontaneous surgical emphysema: an unusual complication of paediatric asthma. 2016 Br J Hosp Med (Lond) pmid:27828753
Serdar Kutuk M et al. Relationship between maternal c-reactive protein level and neonatal outcome in patients with preterm premature rupture of membranes treated with Ampicillin and Azithromycin. 2016 J Obstet Gynaecol pmid:27825282
Ervin AM et al. Surveillance and Azithromycin Treatment for Newcomers and Travelers Evaluation (ASANTE) Trial: Design and Baseline Characteristics. 2016 Ophthalmic Epidemiol pmid:27820670
Weintraub A et al. In-vitro activity of solithromycin against anaerobic bacteria from the normal intestinal microbiota. 2016 Anaerobe pmid:27725229
Wang A et al. Effects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia. 2016 Sci Rep pmid:27405358
Menzel M et al. Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients. 2016 Sci Rep pmid:27350308
O'Beirne SL et al. Trust Your Instincts. Surgical Lung Biopsy with Normal Chest Imaging in a 49-Year-Old Man with Progressive Dyspnea. 2016 Ann Am Thorac Soc pmid:27144798
Committee Opinion No. 645 Summary: Dual Therapy for Gonococcal Infections. 2016 Obstet Gynecol pmid:27548417
Li S et al. Two case reports: Whole genome sequencing of two clinical macrolide-resistant Mycoplasma pneumoniae isolates with different responses to azithromycin. 2016 Medicine (Baltimore) pmid:27661056
Mustapha NA et al. Impact of different antibiotics on methane production using waste-activated sludge: mechanisms and microbial community dynamics. 2016 Appl. Microbiol. Biotechnol. pmid:27531514
Brunner A et al. Emerging azithromycin-resistance among the Neisseria gonorrhoeae strains isolated in Hungary. 2016 Ann. Clin. Microbiol. Antimicrob. pmid:27646968
Molini BJ et al. Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains. 2016 Sex Transm Dis pmid:27513385
Regnath T et al. Antimicrobial resistance of Neisseria gonorrhoeae isolates in south-west Germany, 2004 to 2015: increasing minimal inhibitory concentrations of tetracycline but no resistance to third-generation cephalosporins. 2016 Euro Surveill. pmid:27632642
Xiridou M et al. Cost-Effectiveness of Dual Antimicrobial Therapy for Gonococcal Infections Among Men Who Have Sex With Men in the Netherlands. 2016 Sex Transm Dis pmid:27513379
Mitjà O et al. Mass Treatment with Single-Dose Azithromycin for Yaws. 2016 N. Engl. J. Med. pmid:27626525
Cheng GS et al. Lung Function Trajectory in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplant. 2016 Ann Am Thorac Soc pmid:27513368
Kobuchi S et al. Transport of Azithromycin into Extravascular Space in Rats. 2016 Antimicrob. Agents Chemother. pmid:27600045
Marks M et al. Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma. 2016 PLoS Negl Trop Dis pmid:27551787
Samson C et al. Long-term effects of azithromycin in patients with cystic fibrosis. 2016 Respir Med pmid:27492507
Akram FE et al. A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). 2016 Ann. Clin. Microbiol. Antimicrob. pmid:27530257
Zhou QT et al. How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder? 2016 AAPS J pmid:27255350
MUW researcher of the month Franz Ratzinger. 2016 Wien. Klin. Wochenschr. pmid:27113348
Yuan ZF et al. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with Mycoplasma pneumoniae infection. 2016 BMC Infect. Dis. pmid:27230114
Kloepfer KM Azithromycin may prevent severe respiratory-infection-induced wheezing. 2016 J. Pediatr. pmid:27112084
Liu Y et al. Influence of Omega 3 and 6 Fatty Acids on Human Meibomian Gland Epithelial Cells. 2016 Cornea pmid:27227397
Noda AA et al. First Report of the 23S rRNA Gene A2058G Point Mutation Associated With Macrolide Resistance in Treponema pallidum From Syphilis Patients in Cuba. 2016 Sex Transm Dis pmid:27100771
Haas AN et al. Predictors of clinical outcomes after periodontal treatment of aggressive periodontitis: 12-month randomized trial. 2016 Braz Oral Res pmid:27223128
Itaqui SR et al. In Vitro Synergism between Azithromycin or Terbinafine and Topical Antimicrobial Agents against Pythium insidiosum. 2016 Antimicrob. Agents Chemother. pmid:27216049
Wang Z and Meenach SA Synthesis and Characterization of Nanocomposite Microparticles (nCmP) for the Treatment of Cystic Fibrosis-Related Infections. 2016 Pharm. Res. pmid:27091030
Phong NC et al. In Vivo Efficacy and Tolerability of Artesunate-Azithromycin for the Treatment of Falciparum Malaria in Vietnam. 2016 Am. J. Trop. Med. Hyg. pmid:27215294
Ab Rahman N et al. Antibiotic prescribing in public and private practice: a cross-sectional study in primary care clinics in Malaysia. 2016 BMC Infect. Dis. pmid:27188538
Brown J et al. Shigellosis: high rates of antibiotic resistance necessitate new treatment recommendations. 2016 Med. J. Aust. pmid:27078594
Ramaiah B et al. High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice. 2016 Daru pmid:27150818
Rajabi O et al. Topical liposomal azithromycin in the treatment of acute cutaneous leishmaniasis. 2016 Dermatol Ther pmid:27073044
Kumaraswamy M et al. Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia. 2016 J. Antimicrob. Chemother. pmid:26832758
Arikan S et al. Effect of Topically Applied Azithromycin on Corneal Epithelial and Endothelial Apoptosis in a Rat Model of Corneal Alkali Burn. 2016 Cornea pmid:26751994
Zhou T et al. Fabrication of a Selective and Sensitive Sensor Based on Molecularly Imprinted Polymer/Acetylene Black for the Determination of Azithromycin in Pharmaceuticals and Biological Samples. 2016 PLoS ONE pmid:26820753
Russell DW et al. Disease phenotyping in chronic obstructive pulmonary disease: the neutrophilic endotype. 2016 Curr Opin Pulm Med pmid:26717512
Kadota T et al. Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease. 2016 BMC Infect. Dis. pmid:26818764
Wladis EJ et al. Oral Antibiotics for Meibomian Gland-Related Ocular Surface Disease: A Report by the American Academy of Ophthalmology. 2016 Ophthalmology pmid:26707417
Deshpande D et al. Azithromycin Dose To Maximize Efficacy and Suppress Acquired Drug Resistance in Pulmonary Mycobacterium avium Disease. 2016 Antimicrob. Agents Chemother. pmid:26810646
Stokholm J et al. Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial. 2016 Lancet Respir Med pmid:26704020
Swatton JE et al. Impact of Azithromycin on the Quorum Sensing-Controlled Proteome of Pseudomonas aeruginosa. 2016 PLoS ONE pmid:26808156
Afshar M et al. Azithromycin use and outcomes in severe sepsis patients with and without pneumonia. 2016 J Crit Care pmid:26803186
Lenehan PJ et al. An evaluation strategy for potential QTc prolongation with chronic azithromycin therapy in cystic fibrosis. 2016 J. Cyst. Fibros. pmid:26698953
Lee H et al. New treatment options for infections caused by increasingly antimicrobial-resistant Neisseria gonorrhoeae. 2016 Expert Rev Anti Infect Ther pmid:26690658
Nakajima T et al. Microbiological and Clinical Effects of Sitafloxacin and Azithromycin in Periodontitis Patients Receiving Supportive Periodontal Therapy. 2016 Antimicrob. Agents Chemother. pmid:26729495
Al-Hity A and Lockington D Oral azithromycin as the systemic treatment of choice in the treatment of meibomian gland disease. 2016 Clin. Experiment. Ophthalmol. pmid:26441357
Ruttens D et al. Prophylactic Azithromycin Therapy After Lung Transplantation: Post hoc Analysis of a Randomized Controlled Trial. 2016 Am. J. Transplant. pmid:26372728
Wu TS et al. Postcesarean section wound infection caused by Mycobacterium massiliense. 2016 J Microbiol Immunol Infect pmid:26350122
Li SQ et al. Establishment of a new animal model of azithromycin-induced liver injury and study the molecular pathological change during the process. 2016 Hum Exp Toxicol pmid:26205530
Nappe TM et al. Stevens-Johnson syndrome after treatment with azithromycin: an uncommon culprit. 2016 Am J Emerg Med pmid:26194400
Derad I et al. Hypertension and mild chronic kidney disease persist following severe haemolytic uraemic syndrome caused by Shiga toxin-producing Escherichia coli O104:H4 in adults. 2016 Nephrol. Dial. Transplant. pmid:26180049
Steeples LR et al. Real-time PCR using the 529 bp repeat element for the diagnosis of atypical ocular toxoplasmosis. 2016 Br J Ophthalmol pmid:26174811
Arora N et al. Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster. 2016 Nat Microbiol pmid:27918528
Shimizu T and Suzaki H Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. 2016 Auris Nasus Larynx pmid:26441370