Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Parasitemia D018512 5 associated lipids
Abdominal Abscess D018784 2 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Pseudolymphoma D019310 1 associated lipids
Pouchitis D019449 3 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

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What genes are associated with Azithramycine?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Misra R and Prasad KN Antimicrobial susceptibility to azithromycin among Salmonella enterica Typhi and Paratyphi A isolates from India. 2016 J. Med. Microbiol. pmid:27902389
Paul SP et al. Spontaneous surgical emphysema: an unusual complication of paediatric asthma. 2016 Br J Hosp Med (Lond) pmid:27828753
Hanssens L et al. The clinical benefits of long-term supplementation with omega-3 fatty acids in cystic fibrosis patients - A pilot study. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:27154364
Zhou Y et al. Azithromycin therapy during respiratory syncytial virus bronchiolitis: Upper airway microbiome alterations and subsequent recurrent wheeze. 2016 J. Allergy Clin. Immunol. pmid:27339392
Rosenthal PJ Azithromycin for Malaria? 2016 Am. J. Trop. Med. Hyg. pmid:27215296
Wang A et al. Effects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia. 2016 Sci Rep pmid:27405358
Menzel M et al. Azithromycin induces anti-viral effects in cultured bronchial epithelial cells from COPD patients. 2016 Sci Rep pmid:27350308
O'Beirne SL et al. Trust Your Instincts. Surgical Lung Biopsy with Normal Chest Imaging in a 49-Year-Old Man with Progressive Dyspnea. 2016 Ann Am Thorac Soc pmid:27144798
Nair S et al. WGS for surveillance of antimicrobial resistance: a pilot study to detect the prevalence and mechanism of resistance to azithromycin in a UK population of non-typhoidal Salmonella. 2016 J. Antimicrob. Chemother. pmid:27585964
Mwingira UJ et al. Progress of Trachoma Mapping in Mainland Tanzania: Results of Baseline Surveys from 2012 to 2014. 2016 Ophthalmic Epidemiol pmid:27775455
Wind CM et al. Time to clearance of Chlamydia trachomatis RNA and DNA after treatment in patients coinfected with Neisseria gonorrhoeae - a prospective cohort study. 2016 BMC Infect. Dis. pmid:27724878
Yasuda M et al. Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility of azithromycin and increase in the failure of azithromycin therapy in male gonococcal urethritis in Sendai in 2015. 2016 J. Infect. Chemother. pmid:27578029
Tita AT et al. Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. 2016 N. Engl. J. Med. pmid:27682034
Committee Opinion No. 645: Dual Therapy for Gonococcal Infections. 2016 Obstet Gynecol pmid:27548425
Waites KB et al. In Vitro Activities of Omadacycline (PTK 0796) and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas. 2016 Antimicrob. Agents Chemother. pmid:27671057
Committee Opinion No. 645 Summary: Dual Therapy for Gonococcal Infections. 2016 Obstet Gynecol pmid:27548417
Li S et al. Two case reports: Whole genome sequencing of two clinical macrolide-resistant Mycoplasma pneumoniae isolates with different responses to azithromycin. 2016 Medicine (Baltimore) pmid:27661056
Mustapha NA et al. Impact of different antibiotics on methane production using waste-activated sludge: mechanisms and microbial community dynamics. 2016 Appl. Microbiol. Biotechnol. pmid:27531514
Brunner A et al. Emerging azithromycin-resistance among the Neisseria gonorrhoeae strains isolated in Hungary. 2016 Ann. Clin. Microbiol. Antimicrob. pmid:27646968
Molini BJ et al. Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains. 2016 Sex Transm Dis pmid:27513385
Regnath T et al. Antimicrobial resistance of Neisseria gonorrhoeae isolates in south-west Germany, 2004 to 2015: increasing minimal inhibitory concentrations of tetracycline but no resistance to third-generation cephalosporins. 2016 Euro Surveill. pmid:27632642
Xiridou M et al. Cost-Effectiveness of Dual Antimicrobial Therapy for Gonococcal Infections Among Men Who Have Sex With Men in the Netherlands. 2016 Sex Transm Dis pmid:27513379
Mitjà O et al. Mass Treatment with Single-Dose Azithromycin for Yaws. 2016 N. Engl. J. Med. pmid:27626525
Falay D et al. Microbiological, clinical and molecular findings of non-typhoidal Salmonella bloodstream infections associated with malaria, Oriental Province, Democratic Republic of the Congo. 2016 BMC Infect. Dis. pmid:27286886
Horner PJ et al. 2016 European guideline on the management of non-gonococcal urethritis. 2016 Int J STD AIDS pmid:27147267
El-Shitany NA and El-Desoky K Protective Effects of Carvedilol and Vitamin C against Azithromycin-Induced Cardiotoxicity in Rats via Decreasing ROS, IL1-β, and TNF-α Production and Inhibiting NF-κB and Caspase-3 Expression. 2016 Oxid Med Cell Longev pmid:27274777
Kreuter A and Wieland U Azithromycin versus Doxycycline for Chlamydia. 2016 N. Engl. J. Med. pmid:27144858
García-Quintanilla M et al. Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii. 2016 Antimicrob. Agents Chemother. pmid:27270288
Schachter J Azithromycin versus Doxycycline for Chlamydia. 2016 N. Engl. J. Med. pmid:27144857
Zhou QT et al. How Much Surface Coating of Hydrophobic Azithromycin Is Sufficient to Prevent Moisture-Induced Decrease in Aerosolisation of Hygroscopic Amorphous Colistin Powder? 2016 AAPS J pmid:27255350
MUW researcher of the month Franz Ratzinger. 2016 Wien. Klin. Wochenschr. pmid:27113348
Yuan ZF et al. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with Mycoplasma pneumoniae infection. 2016 BMC Infect. Dis. pmid:27230114
Kloepfer KM Azithromycin may prevent severe respiratory-infection-induced wheezing. 2016 J. Pediatr. pmid:27112084
Liu Y et al. Influence of Omega 3 and 6 Fatty Acids on Human Meibomian Gland Epithelial Cells. 2016 Cornea pmid:27227397
Noda AA et al. First Report of the 23S rRNA Gene A2058G Point Mutation Associated With Macrolide Resistance in Treponema pallidum From Syphilis Patients in Cuba. 2016 Sex Transm Dis pmid:27100771
Haas AN et al. Predictors of clinical outcomes after periodontal treatment of aggressive periodontitis: 12-month randomized trial. 2016 Braz Oral Res pmid:27223128
Marks M et al. Mass drug administration of azithromycin for trachoma reduces the prevalence of genital Chlamydia trachomatis infection in the Solomon Islands. 2016 Sex Transm Infect pmid:26888658
Economopoulos KP et al. Prevention of antibiotic-associated metabolic syndrome in mice by intestinal alkaline phosphatase. 2016 Diabetes Obes Metab pmid:26876427
Kang JY et al. Long-term azithromycin ameliorates not only airway inflammation but also remodeling in a murine model of chronic asthma. 2016 Pulm Pharmacol Ther pmid:26778828
Sridhar S et al. High recurrence rate supports need for secondary prophylaxis in non-HIV patients with disseminated mycobacterium avium complex infection: a multi-center observational study. 2016 BMC Infect. Dis. pmid:26861696
Peters RP et al. Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome. 2016 Sex Transm Dis pmid:26760182
Hodgson D et al. The Effects of Azithromycin in Treatment-Resistant Cough: A Randomized, Double-Blind, Placebo-Controlled Trial. 2016 Chest pmid:26836927
Zheng Z et al. Synthesis and antibacterial activity of novel 11-[3-[(arylcarbamoyl)oxy]propylamino]-11-deoxy-6-O-methyl-3-oxoerythromycin A 11-N,12-O-cyclic carbamate derivatives. 2016 J. Antibiot. pmid:27118243
Gratrix J et al. A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men. 2016 Sex Transm Dis pmid:26760180
Kumaraswamy M et al. Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia. 2016 J. Antimicrob. Chemother. pmid:26832758
Arikan S et al. Effect of Topically Applied Azithromycin on Corneal Epithelial and Endothelial Apoptosis in a Rat Model of Corneal Alkali Burn. 2016 Cornea pmid:26751994
Zhou T et al. Fabrication of a Selective and Sensitive Sensor Based on Molecularly Imprinted Polymer/Acetylene Black for the Determination of Azithromycin in Pharmaceuticals and Biological Samples. 2016 PLoS ONE pmid:26820753
Russell DW et al. Disease phenotyping in chronic obstructive pulmonary disease: the neutrophilic endotype. 2016 Curr Opin Pulm Med pmid:26717512
Kadota T et al. Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease. 2016 BMC Infect. Dis. pmid:26818764
Wladis EJ et al. Oral Antibiotics for Meibomian Gland-Related Ocular Surface Disease: A Report by the American Academy of Ophthalmology. 2016 Ophthalmology pmid:26707417
Deshpande D et al. Azithromycin Dose To Maximize Efficacy and Suppress Acquired Drug Resistance in Pulmonary Mycobacterium avium Disease. 2016 Antimicrob. Agents Chemother. pmid:26810646
Stokholm J et al. Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years: a randomised, double-blind, placebo-controlled trial. 2016 Lancet Respir Med pmid:26704020
Nicholson TT et al. Assessing potential risks of treatment with long-term azithromycin in COPD patients: long-term oxygen users beware? 2016 Ir J Med Sci pmid:26502012
Deguchi T et al. Multidrug-Resistant Mycoplasma genitalium Is Increasing. 2016 Clin. Infect. Dis. pmid:26494825
Kong FY et al. Reply to Deguchi et al. 2016 Clin. Infect. Dis. pmid:26494824
Ruttens D et al. Prophylactic Azithromycin Therapy After Lung Transplantation: Post hoc Analysis of a Randomized Controlled Trial. 2016 Am. J. Transplant. pmid:26372728
Osborne LG et al. Enteric fever in a British soldier from Sierra Leone. 2016 J R Army Med Corps pmid:26243802
Li SQ et al. Establishment of a new animal model of azithromycin-induced liver injury and study the molecular pathological change during the process. 2016 Hum Exp Toxicol pmid:26205530
Shimizu T and Suzaki H Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. 2016 Auris Nasus Larynx pmid:26441370
Chang CC et al. Disseminated cat-scratch disease: case report and review of the literature. 2016 Paediatr Int Child Health pmid:25940800
Hazra A Author Reply. 2016 Jan-Feb Indian J Pharmacol pmid:26997735
Das S and Mohanty M Comparative evaluation of 2 g single dose versus conventional dose azithromycin in uncomplicated skin and skin structure infections. 2016 Jan-Feb Indian J Pharmacol pmid:26997734
Das A et al. Azithromycin induced bullous fixed drug eruption. 2016 Jan-Feb Indian J Pharmacol pmid:26997729
Chatterjee S et al. Azithromycin susceptibility among clinical isolates of Salmonella: Interfacing guidelines with routine practices. 2016 Jul-Sep Indian J Med Microbiol pmid:27514976
Latif SA et al. Azithromycin buccal patch in treatment of chronic periodontitis. 2016 Mar-Apr Indian J Pharmacol pmid:27127325
Oliveira IS et al. Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. 2016 Mar-Apr Braz J Otorhinolaryngol pmid:26601998
Akoglu G et al. Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. 2016 May-Jun Indian J Pharmacol pmid:27298507
Diniz LM et al. Bacillary angiomatosis with bone invasion. 2016 Nov-Dec An Bras Dermatol pmid:28099606
O'Brien KS et al. Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial. 2017 Am. J. Trop. Med. Hyg. pmid:28722569
Stoney RJ et al. Travelers' Diarrhea and Other Gastrointestinal Symptoms Among Boston-Area International Travelers. 2017 Am. J. Trop. Med. Hyg. pmid:28719282
Harper LM et al. Economic Evaluation of Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. 2017 Obstet Gynecol pmid:28697108
Fan LC et al. Macrolides protect against infection via inhibition of inflammasomes. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28684545
Wang Y et al. Synthesis and antibacterial activity of novel 4″-O-(1-aralkyl-1,2,3-triazol-4-methyl-carbamoyl) azithromycin analogs. 2017 Bioorg. Med. Chem. Lett. pmid:28655423
Bystrzycka W et al. Azithromycin and Chloramphenicol Diminish Neutrophil Extracellular Traps (NETs) Release. 2017 Int J Mol Sci pmid:29292737
Pavlinac PB et al. Azithromycin to prevent post-discharge morbidity and mortality in Kenyan children: a protocol for a randomised, double-blind, placebo-controlled trial (the Toto Bora trial). 2017 BMJ Open pmid:29289941
Giguère S et al. Antimicrobial Resistance in . 2017 Microbiol Spectr pmid:29052538
Ullah S et al. Creatinine-based non-phospholipid vesicular carrier for improved oral bioavailability of Azithromycin. 2017 Drug Dev Ind Pharm pmid:28157445
Mohammed H et al. First line dual therapy for gonorrhoea to limit the spread of antimicrobial resistance. 2017 BMJ pmid:28153820
Oluwalana C et al. Azithromycin in Labor Lowers Clinical Infections in Mothers and Newborns: A Double-Blind Trial. 2017 Pediatrics pmid:28130432
Gerber JS and Zaoutis TE Azithromycin Prophylaxis for Laboring Mothers. 2017 Pediatrics pmid:28130431
Cogen JD et al. Characterization of Inpatient Cystic Fibrosis Pulmonary Exacerbations. 2017 Pediatrics pmid:28126911
Cramer CL et al. Immunomodulatory indications of azithromycin in respiratory disease: a concise review for the clinician. 2017 Postgrad Med pmid:28116959
Gibson PG et al. Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. 2017 Lancet pmid:28687413
Molefe NI et al. Oral administration of azithromycin ameliorates trypanosomosis in Trypanosoma congolense-infected mice. 2017 Parasitol. Res. pmid:28674747
Batteiger BE Azithromycin Efficacy in Asymptomatic Rectal Chlamydial Infection in Men Who Have Sex With Men: A More Definitive Answer Soon? 2017 Sex Transm Dis pmid:28604482
Sonavane AD and Rathi PM Fitz-Hugh-Curtis syndrome. 2017 Indian J. Med. Res. pmid:28574030
Ra SW et al. Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. 2017 Respir. Res. pmid:28558695
Varano GP et al. Post-ischemic treatment with azithromycin protects ganglion cells against retinal ischemia/reperfusion injury in the rat. 2017 Mol. Vis. pmid:29296071
Haque F et al. Evaluation of a Smartphone Decision-Support Tool for Diarrheal Disease Management in a Resource-Limited Setting. 2017 PLoS Negl Trop Dis pmid:28103233
Bulman ZP et al. Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin. 2017 Antimicrob. Agents Chemother. pmid:28096154
Wind CM et al. Trends in antimicrobial susceptibility for azithromycin and ceftriaxone in Neisseria gonorrhoeae isolates in Amsterdam, the Netherlands, between 2012 and 2015. 2017 Euro Surveill. pmid:28079519
Tita ATN et al. Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. 2017 N. Engl. J. Med. pmid:28076707
Björnelius E et al. macrolide resistance in Stockholm, Sweden. 2017 Sex Transm Infect pmid:27502694
O'Rourke VJ Azithromycin as an adjunct to non-surgical periodontal therapy: a systematic review. 2017 Aust Dent J pmid:27492140
Xue Y et al. An in vitro model of azithromycin-induced persistent Chlamydia trachomatis infection. 2017 FEMS Microbiol. Lett. pmid:28854672
Barberá MJ et al. Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance: Prevalence and Risk Factors Among a 2013-2014 Cohort of Patients in Barcelona, Spain. 2017 Sex Transm Dis pmid:28703723
Brusselle G and Pavord I Azithromycin in uncontrolled asthma. 2017 Lancet pmid:28687412
Murray K et al. Increasing Antibiotic Resistance in Shigella spp. from Infected New York City Residents, New York, USA. 2017 Emerging Infect. Dis. pmid:28098543
Nichols DP et al. Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis. 2017 J. Cyst. Fibros. pmid:28025037
Marks M et al. Mathematical Modeling of Programmatic Requirements for Yaws Eradication. 2017 Emerging Infect. Dis. pmid:27983500