Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Toxoplasmosis, Ocular D014126 2 associated lipids
Typhoid Fever D014435 2 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Leishmaniasis, Mucocutaneous D007897 1 associated lipids
Trichiasis D058457 1 associated lipids
Paratyphoid Fever D010284 1 associated lipids
Ectodermal Dysplasia D004476 1 associated lipids
Tooth Erosion D014077 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Ishida K et al. In vitro and in vivo activities of macrolides against Mycoplasma pneumoniae. 1994 Antimicrob. Agents Chemother. pmid:8031048
Dorrell L et al. Intravenous azithromycin as salvage therapy in a patient with Legionnaire's disease. 1994 Thorax pmid:8016806
Klepser ME et al. Treatment of uncomplicated infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae. 1994 Conn Med pmid:7924316
Wallace MR et al. Ototoxicity with azithromycin. 1994 Lancet pmid:7904701
Klemens SP and Cynamon MH Intermittent azithromycin for treatment of Mycobacterium avium infection in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7986001
Andersen SL et al. Efficacy of azithromycin as a causal prophylactic agent against murine malaria. 1994 Antimicrob. Agents Chemother. pmid:7986022
Cazzola M et al. Evaluation of lung tissue and hilar lymph node concentrations of azithromycin. 1994 Int J Clin Pharmacol Ther pmid:8004364
Hughes WT et al. Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model. 1994 J. Infect. Dis. pmid:7930735
Niki Y et al. In vitro and in vivo activities of azithromycin, a new azalide antibiotic, against chlamydia. 1994 Antimicrob. Agents Chemother. pmid:7840560
Freeman CD et al. Intracellular and extracellular penetration of azithromycin into inflammatory and noninflammatory blister fluid. 1994 Antimicrob. Agents Chemother. pmid:7840585
Wildfeuer A et al. Distribution of orally administered azithromycin in various blood compartments. 1994 Int J Clin Pharmacol Ther pmid:7952797
Bottaro G et al. [Evaluation of the clinical efficacy of azithromycin in acute respiratory infections in children]. 1994 Clin Ter pmid:7955949
Sifrim D et al. Comparison of the effects of midecamycin acetate and azithromycin on gastrointestinal motility in man. 1994 Drugs Exp Clin Res pmid:7956719
Dumas JL et al. Evaluation of the efficacy of prolonged administration of azithromycin in a murine model of chronic toxoplasmosis. 1994 J. Antimicrob. Chemother. pmid:7961197
Uzun O et al. Efficacy of a three-day course of azithromycin in the treatment of community-acquired pneumococcal pneumonia. Preliminary report. 1994 J Chemother pmid:8071680
Benson CA Treatment of disseminated disease due to the Mycobacterium avium complex in patients with AIDS. 1994 Clin. Infect. Dis. pmid:8204776
Parent M [Initial empiric treatment of pneumonia and the new antibiotics]. 1994 Union Med Can pmid:8109061
Bosatra A et al. [Effectiveness of and tolerance to azithromycin versus roxithromycin in the treatment of patients with acute infections of the upper respiratory tract]. 1994 Clin Ter pmid:8168348
Kuschner RA et al. Azithromycin prophylaxis against a chloroquine-resistant strain of Plasmodium falciparum. 1994 Lancet pmid:7910886
Rakita RM et al. Intracellular activity of azithromycin against bacterial enteric pathogens. 1994 Antimicrob. Agents Chemother. pmid:7810998