| MeSH term | MeSH ID | Detail |
|---|---|---|
| Toxoplasmosis, Ocular | D014126 | 2 associated lipids |
| Typhoid Fever | D014435 | 2 associated lipids |
| Acquired Hyperostosis Syndrome | D020083 | 1 associated lipids |
| Central Nervous System Protozoal Infections | D020808 | 3 associated lipids |
| Syncope, Vasovagal | D019462 | 1 associated lipids |
| Leishmaniasis, Mucocutaneous | D007897 | 1 associated lipids |
| Trichiasis | D058457 | 1 associated lipids |
| Paratyphoid Fever | D010284 | 1 associated lipids |
| Ectodermal Dysplasia | D004476 | 1 associated lipids |
| Tooth Erosion | D014077 | 2 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Graybill JR and Bocanegra R | Treatment alternatives for Mycobacterium kansasii. | 2001 | J. Antimicrob. Chemother. | pmid:11266413 |
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| Butler T et al. | In vitro effects of azithromycin on Salmonella typhi: early inhibition by concentrations less than the MIC and reduction of MIC by alkaline pH and small inocula. | 2001 | J. Antimicrob. Chemother. | pmid:11266420 |
| Kawamura-Sato K et al. | Postantibiotic suppression effect of macrolides on the expression of flagellin in Pseudomonas aeruginosa and Proteus mirabilis. | 2001 | J. Infect. Chemother. | pmid:11406758 |
| Kurdowska A et al. | The effect of azithromycin and clarithromycin on ex vivo interleukin-8 (IL-8) release from whole blood and IL-8 production by human alveolar macrophages. | 2001 | J. Antimicrob. Chemother. | pmid:11389120 |
| Thompson C et al. | A family cluster of Chlamydia trachomatis infection. | 2001 | BMJ | pmid:11408308 |
| Jacobson GF et al. | A randomized controlled trial comparing amoxicillin and azithromycin for the treatment of Chlamydia trachomatis in pregnancy. | 2001 | Am. J. Obstet. Gynecol. | pmid:11408852 |
| Matsunaga T | [Pharmacological and pharmacokinetic properties of azithromycin (Zithromac), a novel 15-membered ring macrolide antibacterial agent]. | 2001 | Nippon Yakurigaku Zasshi | pmid:11411344 |
| Kain KC et al. | Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens. | 2001 | Clin. Infect. Dis. | pmid:11418883 |
| Tabbara KF | Trachoma: a review. | 2001 | J Chemother | pmid:11434524 |
| Lisby G et al. | Bacteremia and meningitis caused by a macrolide-sensitive strain of Streptococcus pneumoniae during treatment with azithromycin. | 2001 | Clin. Infect. Dis. | pmid:11438918 |
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| Tyteca D et al. | Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosis in cultured fibroblasts. | 2001 | Eur. J. Cell Biol. | pmid:11499789 |
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| Solera J et al. | Azithromycin and gentamicin therapy for the treatment of humans with brucellosis. | 2001 | Clin. Infect. Dis. | pmid:11170962 |
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| Conrad DA | Treatment of cat-scratch disease. | 2001 | Curr. Opin. Pediatr. | pmid:11176245 |
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| Cascaval RI and Lancaster DJ | Hypersensitivity syndrome associated with azithromycin. | 2001 | Am. J. Med. | pmid:11247598 |
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| De Diego JI et al. | Comparison of amoxicillin and azithromycin in the prevention of recurrent acute otitis media. | 2001 | Int. J. Pediatr. Otorhinolaryngol. | pmid:11249979 |
| Ioannidis JP et al. | Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for upper respiratory tract infections. | 2001 | J. Antimicrob. Chemother. | pmid:11679557 |
| Contopoulos-Ioannidis DG et al. | Meta-analysis of randomized controlled trials on the comparative efficacy and safety of azithromycin against other antibiotics for lower respiratory tract infections. | 2001 | J. Antimicrob. Chemother. | pmid:11679558 |
| Laurent J et al. | A randomized comparison of four omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. | 2001 | Aliment. Pharmacol. Ther. | pmid:11683693 |
| Woolard S and Kenkel D | Heading off antibiotic resistance. | 2001 | Adv Nurse Pract | pmid:12420432 |
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| Weigl LB et al. | [Confluent and reticulate papillomatosis. Successful therapy with azithromycin]. | 2001 | Hautarzt | pmid:11715390 |
| Gray RH et al. | Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda. | 2001 | Am. J. Obstet. Gynecol. | pmid:11717659 |
| Intrauterine devices: antibiotic prophylaxis not necessary during insertion. | 2001 | Prescrire Int | pmid:11718174 | |
| Golledge CL and Riley TV | The efficacy of an antibiotic protocol for community-acquired pneumonia. | 2001 | Med. J. Aust. | pmid:11700844 |
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| Gray GC et al. | Randomized, placebo-controlled clinical trial of oral azithromycin prophylaxis against respiratory infections in a high-risk, young adult population. | 2001 | Clin. Infect. Dis. | pmid:11528569 |
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| Miyazaki S et al. | Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice. | 2001 | J. Antimicrob. Chemother. | pmid:11533011 |
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| Arellano-Rodrigo E et al. | [Torsade de pointes and cardiorespiratory arrest induced by azithromycin in a patient with congenital long QT syndrome]. | 2001 | Med Clin (Barc) | pmid:11459586 |
| Dillon JA et al. | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from three Caribbean countries: Trinidad, Guyana, and St. Vincent. | 2001 | Sex Transm Dis | pmid:11518867 |
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| Doern GV | Antimicrobial use and the emergence of antimicrobial resistance with Streptococcus pneumoniae in the United States. | 2001 | Clin. Infect. Dis. | pmid:11524718 |
| Noedl H et al. | Antimalarial activity of azithromycin, artemisinin and dihydroartemisinin in fresh isolates of Plasmodium falciparum in Thailand. | 2001 | Acta Trop. | pmid:11495642 |
| Fraser-Hurt N et al. | Efficacy of oral azithromycin versus topical tetracycline in mass treatment of endemic trachoma. | 2001 | Bull. World Health Organ. | pmid:11477966 |
| Skerk V et al. | Azithromycin and doxycycline in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum: significance of duration of clinical symptoms. | 2001 | Drugs Exp Clin Res | pmid:11822223 |
| Samra Z et al. | In vitro susceptibility of recent clinical isolates of Chlamydia trachomatis to macrolides and tetracyclines. | 2001 | Diagn. Microbiol. Infect. Dis. | pmid:11337185 |
| Martinez SM et al. | Azithromycin prophylaxis during a hospitalwide outbreak of a pertussis-like illness. | 2001 | Infect Control Hosp Epidemiol | pmid:11876458 |
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| Mendes CM et al. | In vitro susceptibility of gram-positive cocci isolated from skin and respiratory tract to azithromycin and twelve other antimicrobial agents. | 2001 | Braz J Infect Dis | pmid:11779453 |
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| Griffith DE et al. | Azithromycin-containing regimens for treatment of Mycobacterium avium complex lung disease. | 2001 | Clin. Infect. Dis. | pmid:11340525 |
| Tan JS et al. | Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila. | 2001 | Clin. Infect. Dis. | pmid:11340527 |
| Westfall DS et al. | Inoculation of two genotypes of Hemobartonella felis (California and Ohio variants) to induce infection in cats and the response to treatment with azithromycin. | 2001 | Am. J. Vet. Res. | pmid:11341386 |
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| Jacobson JM et al. | Dose-escalation, phase I/II study of azithromycin and pyrimethamine for the treatment of toxoplasmic encephalitis in AIDS. | 2001 | AIDS | pmid:11316995 |
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| Parsad D et al. | Azithromycin monthly pulse vs daily doxycycline in the treatment of acne vulgaris. | 2001 | J. Dermatol. | pmid:11280457 |
| Waring AL et al. | Development of a genomics-based PCR assay for detection of Mycoplasma pneumoniae in a large outbreak in New York State. | 2001 | J. Clin. Microbiol. | pmid:11283060 |
| Lechner A and Bruckner DA | Oligella ureolytica in blood culture: contaminant or infection? | 2001 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11305472 |
| Nagata T et al. | [Two cases successfully treated with long-term administration of low-dosage azithromycin]. | 2001 | Jpn J Antibiot | pmid:12575407 |
| Dreses-Werringloer U et al. | Effects of azithromycin and rifampin on Chlamydia trachomatis infection in vitro. | 2001 | Antimicrob. Agents Chemother. | pmid:11600348 |
| Littler WA | Clindamycin suspension and endocarditis prophylaxis. | 2001 | Br Dent J | pmid:11352383 |
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| Tateda K et al. | Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa. | 2001 | Antimicrob. Agents Chemother. | pmid:11353657 |
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| Pechère JC | Azithromycin reduces the production of virulence factors in Pseudomonas aeruginosa by inhibiting quorum sensing. | 2001 | Jpn J Antibiot | pmid:12575427 |
| Holm SO et al. | Comparison of two azithromycin distribution strategies for controlling trachoma in Nepal. | 2001 | Bull. World Health Organ. | pmid:11285662 |
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| Frick KD et al. | Cost-effectiveness of trachoma control measures: comparing targeted household treatment and mass treatment of children. | 2001 | Bull. World Health Organ. | pmid:11285663 |
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| Sorvillo F et al. | Incidence and determinants of Pseudomonas aeruginosa infection among persons with HIV: association with hospital exposure. | 2001 | Am J Infect Control | pmid:11287873 |
| Edelstein PH et al. | In vitro activity of gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and its pharmacokinetics in guinea pigs with L. pneumophila pneumonia. | 2001 | Antimicrob. Agents Chemother. | pmid:11451675 |
| Rubinstein E | Comparative safety of the different macrolides. | 2001 | Int. J. Antimicrob. Agents | pmid:11574199 |
| Skerk V et al. | Duration of clinical symptoms in female patients with acute urethral syndrome caused by Chlamydia trachomatis treated with azithromycin or doxycycline. | 2001 | J Chemother | pmid:11330365 |
| RodrÃguez Núñez A et al. | [Chemoprophylaxis of meningococcal disease with azithromycin and ciprofloxacin]. | 2001 | An. Esp. Pediatr. | pmid:11333489 |
| Grand A et al. | [Subacute infectious endocarditis due to the agent of cat scratch fever: Bartonella henselae]. | 2001 | Arch Mal Coeur Vaiss | pmid:11265556 |