Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Central Nervous System Protozoal Infections D020808 3 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Mucositis D052016 7 associated lipids
Tendinopathy D052256 3 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

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Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Díaz Sánchez M et al. [New medications: azithromycin]. 1993 Jul-Sep Rev Med Univ Navarra pmid:8134755
Odugbemi T et al. Single oral dose of azithromycin for therapy of susceptible sexually transmitted diseases: a multicenter open evaluation. 1993 Jul-Sep West Afr J Med pmid:8312208
Minguez F et al. In vitro killing kinetics and postantibiotic effect of josamycin and other macrolides on several bacteria. 1993 May-Jun Chemotherapy pmid:8389685
Weber K et al. Azithromycin versus penicillin V for the treatment of early Lyme borreliosis. 1993 Nov-Dec Infection pmid:8132365
Scaglione F et al. A new model examining intracellular and extracellular activity of amoxicillin, azithromycin, and clarithromycin in infected cells. 1993 Nov-Dec Chemotherapy pmid:8222870
Braga PC and Piatti G Interference by subinhibitory concentrations of azithromycin with the mechanism of bacterial adhesion to human epithelial cells. 1993 Nov-Dec Chemotherapy pmid:8222872
Goldman MP and Longworth DL The role of azithromycin and clarithromycin in clinical practice. 1993 Sep-Oct Cleve Clin J Med pmid:8403355
Donowitz GR Tissue-directed antibiotics and intracellular parasites: complex interaction of phagocytes, pathogens, and drugs. 1994 Clin. Infect. Dis. pmid:7893881
Beale AS and Upshon PA Characteristics of murine model of genital infection with Chlamydia trachomatis and effects of therapy with tetracyclines, amoxicillin-clavulanic acid, or azithromycin. 1994 Antimicrob. Agents Chemother. pmid:7811001
Carlier MB et al. Accumulation, release and subcellular localization of azithromycin in phagocytic and non-phagocytic cells in culture. 1994 Int J Tissue React pmid:7558665
Management of genital Chlamydia trachomatis infections. 1994 Drug Ther Bull pmid:7635012
Steven N et al. Corticosteroid therapy for AIDS patients with Mycobacterium avium-intracellulare infection. 1994 AIDS pmid:8011231
Chiarini F et al. Chlamydia trachomatis genitourinary infections: laboratory diagnosis and therapeutic aspects. Evaluation of in vitro and in vivo effectiveness of azithromycin. 1994 J Chemother pmid:7830100
Wang JH et al. Azithromycin in the treatment of pneumonia caused by Chlamydia pneumoniae: report of a case. 1994 J. Formos. Med. Assoc. pmid:7866068
[Newly approved specialty drugs in Austria and new knowledge about currently available specialty drugs. Zithromax capsules, dried syrup]. 1994 Wien. Klin. Wochenschr. pmid:7975673
Cynamon MH et al. Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7979270
Klemens SP and Cynamon MH Activities of azithromycin and clarithromycin against nontuberculous mycobacteria in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7979271
Schönwald S et al. Three-day azithromycin compared with ten-day roxithromycin treatment of atypical pneumonia. 1994 Scand. J. Infect. Dis. pmid:7747094
Schwab JC et al. Localization of azithromycin in Toxoplasma gondii-infected cells. 1994 Antimicrob. Agents Chemother. pmid:7979295
[Azithromycin--an innovative macrolide antibiotic for 3-day-therapy]. 1994 Immun. Infekt. pmid:7982710