| MeSH term | MeSH ID | Detail |
|---|---|---|
| Epiglottitis | D004826 | 1 associated lipids |
| Furcation Defects | D017823 | 1 associated lipids |
| Pseudolymphoma | D019310 | 1 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Corneal Endothelial Cell Loss | D055954 | 1 associated lipids |
| Asymptomatic Infections | D058345 | 1 associated lipids |
| Aphasia, Broca | D001039 | 1 associated lipids |
| Heartburn | D006356 | 2 associated lipids |
| Eisenmenger Complex | D004541 | 1 associated lipids |
| Focal Nodular Hyperplasia | D020518 | 1 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hublikar S et al. | Disseminated gonococcal infection and eculizumab--a "high risk" connection? | 2014 | Sex Transm Dis | pmid:25581812 |
| Na YJ et al. | An imported case of severe falciparum malaria with prolonged hemolytic anemia clinically mimicking a coinfection with babesiosis. | 2014 | Korean J. Parasitol. | pmid:25548419 |
| Safari D et al. | Increase in the rate of azithromycin-resistant Streptococcus pneumoniae isolates carrying the erm(B) and mef(A) genes in Taiwan, 2006-2010. | 2014 | BMC Infect. Dis. | pmid:25527193 |
| Hincapié JP et al. | Microbiological effects of periodontal therapy plus azithromycin in patients with diabetes: results from a randomized clinical trial. | 2014 | Acta Odontol Latinoam | pmid:25523961 |
| Ratzinger F et al. | Azithromycin suppresses CD4(+) T-cell activation by direct modulation of mTOR activity. | 2014 | Sci Rep | pmid:25500904 |
| Krásny J et al. | The role of Chlamydia pneumoniae in the etiology of keratoconjunctivitis sicca (KCS). | 2014 | Recent Pat Inflamm Allergy Drug Discov | pmid:25395268 |
| Legrand T et al. | An optimal LC-MS/MS method for determination of azithromycin in white blood cells: application to pediatric samples. | 2014 | Bioanalysis | pmid:25383741 |
| Maisch NM et al. | Azithromycin and the risk of cardiovascular complications. | 2014 | J Pharm Pract | pmid:25374989 |
| Restrepo MI and Anzueto A | Reply: Azithromycin: We're there! | 2014 | Am. J. Respir. Crit. Care Med. | pmid:25360733 |
| Albert RK et al. | Azithromycin: We're there! | 2014 | Am. J. Respir. Crit. Care Med. | pmid:25360732 |
| Collins DP et al. | Fever, wet cough, rash-Dx? | 2014 | J Fam Pract | pmid:25353030 |
| Shin B et al. | Changes in QT intervals after azithromycin-containing antibiotic therapy in patients with NTM lung disease. | 2014 | Int. J. Tuberc. Lung Dis. | pmid:25299875 |
| Yu T and Niu T | Giant inverted T waves and substantial QT interval prolongation induced by azithromycin in an elderly woman with renal insufficiency. | 2014 | Can Fam Physician | pmid:25392441 |
| Benwill JL and Wallace RJ | Mycobacterium abscessus: challenges in diagnosis and treatment. | 2014 | Curr. Opin. Infect. Dis. | pmid:25268925 |
| Nie W et al. | [The analysis of species identification and susceptibility testing of Mycobacterium abscessus]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:25262693 |
| Heiman KE et al. | Shigellosis with decreased susceptibility to azithromycin. | 2014 | Pediatr. Infect. Dis. J. | pmid:25361413 |
| Meyer KC et al. | An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome. | 2014 | Eur. Respir. J. | pmid:25359357 |
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| Dhakad U et al. | Arthritis and adult respiratory distress syndrome: unusual presentations of typhoid fever. | 2014 | BMJ Case Rep | pmid:25336548 |
| Davis AR et al. | Sequence selectivity of macrolide-induced translational attenuation. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25313041 |
| Haworth CS et al. | Long-term macrolide maintenance therapy in non-CF bronchiectasis: evidence and questions. | 2014 | Respir Med | pmid:25301290 |
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| Zhang C et al. | Preparation and characterization of novel microparticles based on poly(3-hydroxybutyrate-co-3-hydroxyoctanoate). | 2014 | J Microencapsul | pmid:23701218 |
| Zhu BY et al. | Surveillance of antimicrobial susceptibilities of Neisseria gonorrhoeae in Nanning, China, 2000 to 2012. | 2014 | Sex Transm Dis | pmid:25013979 |
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| Yasuda M et al. | A single 2 g oral dose of extended-release azithromycin for treatment of gonococcal urethritis. | 2014 | J. Antimicrob. Chemother. | pmid:24948703 |
| Mendes-Bastos P et al. | Non-occupational allergic contact dermatitis caused by azithromycin in an eye solution. | 2014 | J Dtsch Dermatol Ges | pmid:24943901 |
| Kingah PL et al. | Azithromycin improves lung function in patients with post-lung transplant bronchiolitis obliterans syndrome: a meta-analysis. | 2014 | Clin Transplant | pmid:24931185 |
| Zhanel GG et al. | Clinical cure rates in subjects treated with azithromycin for community-acquired respiratory tract infections caused by azithromycin-susceptible or azithromycin-resistant Streptococcus pneumoniae: analysis of Phase 3 clinical trial data. | 2014 | J. Antimicrob. Chemother. | pmid:24920652 |
| Oates TW | Understanding the effects of periodontal therapy plus azithromycin on glycemic control in patients with diabetes remains elusive. | 2014 | J Evid Based Dent Pract | pmid:24913532 |
| Yamada K et al. | Azithromycin inhibits MUC5AC induction via multidrug-resistant Acinetobacter baumannii in human airway epithelial cells. | 2014 | Pulm Pharmacol Ther | pmid:24910464 |
| Berlutti F et al. | Influence of sub-inhibitory antibiotics and flow condition on Staphylococcus aureus ATCC 6538 biofilm development and biofilm growth rate: BioTimer assay as a study model. | 2014 | J. Antibiot. | pmid:24865865 |
| Taylor-Robinson D | Diagnosis and antimicrobial treatment of Mycoplasma genitalium infection: sobering thoughts. | 2014 | Expert Rev Anti Infect Ther | pmid:24834454 |
| Ray WA | Azithromycin associated with a reduction in 90-day mortality among older pneumonia patients, although a true clinical benefit is uncertain. | 2014 | Evid Based Med | pmid:25121563 |
| Burr SE et al. | Mass administration of azithromycin and Streptococcus pneumoniae carriage: cross-sectional surveys in the Gambia. | 2014 | Bull. World Health Organ. | pmid:25110374 |
| Brunner A et al. | Incidence and antimicrobial susceptibility of Neisseria gonorrhoeae isolates from patients attending the national Neisseria gonorrhoeae reference laboratory of Hungary. | 2014 | BMC Infect. Dis. | pmid:25098185 |
| Mikals K et al. | Campylobacter fetus bacteremia in an immunocompetent traveler. | 2014 | Am. J. Trop. Med. Hyg. | pmid:25071002 |
| Carannante A et al. | Changing antimicrobial resistance profiles among Neisseria gonorrhoeae isolates in Italy, 2003 to 2012. | 2014 | Antimicrob. Agents Chemother. | pmid:25070110 |
| Kirkcaldy RD et al. | The efficacy and safety of gentamicin plus azithromycin and gemifloxacin plus azithromycin as treatment of uncomplicated gonorrhea. | 2014 | Clin. Infect. Dis. | pmid:25031289 |
| Jenson A et al. | Gender and performance of community treatment assistants in Tanzania. | 2014 | Int J Qual Health Care | pmid:25022350 |
| Shirey KA et al. | Agents that increase AAM differentiation blunt RSV-mediated lung pathology. | 2014 | J. Leukoc. Biol. | pmid:25009233 |
| Patsche CB et al. | Disseminated Mycobacterium celatum disease with prolonged pulmonary involvement. | 2014 | Int. J. Infect. Dis. | pmid:25008771 |
| Jesus FP et al. | In vitro synergism observed with azithromycin, clarithromycin, minocycline, or tigecycline in association with antifungal agents against Pythium insidiosum. | 2014 | Antimicrob. Agents Chemother. | pmid:25001300 |
| Miura Y et al. | Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma parvum from the amniotic fluid in an ovine model of intrauterine infection. | 2014 | Antimicrob. Agents Chemother. | pmid:24982089 |
| Nguyen D et al. | Neisseria gonorrhoeae strain with reduced susceptibilities to extended-spectrum cephalosporins. | 2014 | Emerging Infect. Dis. | pmid:24964277 |
| Sulis G et al. | Chlamydia trachomatis conjunctivitis in a male teenager: a case report. | 2014 | Infez Med | pmid:24955802 |
| Parnham MJ et al. | Azithromycin: mechanisms of action and their relevance for clinical applications. | 2014 | Pharmacol. Ther. | pmid:24631273 |
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| Grobost V et al. | Suppressive therapy using azithromycin in 2 rare cases of recurrent staphylococcal infections. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:24629578 |
| Vandepitte J et al. | High prevalence of ciprofloxacin-resistant gonorrhea among female sex workers in Kampala, Uganda (2008-2009). | 2014 | Sex Transm Dis | pmid:24622633 |
| Takayama Y et al. | Characterization of azithromycin-resistant Neisseria gonorrhoeae isolated in Tokyo in 2005-2011. | 2014 | J. Infect. Chemother. | pmid:24571786 |
| Choi EY et al. | Effect of azithromycin on Prevotella intermedia lipopolysaccharide-induced production of interleukin-6 in murine macrophages. | 2014 | Eur. J. Pharmacol. | pmid:24534490 |
| Maurer FP et al. | Erm(41)-dependent inducible resistance to azithromycin and clarithromycin in clinical isolates of Mycobacterium abscessus. | 2014 | J. Antimicrob. Chemother. | pmid:24500188 |
| Hassing RJ et al. | Case of Shigella flexneri infection with treatment failure due to azithromycin resistance in an HIV-positive patient. | 2014 | Infection | pmid:24488332 |
| Kohno S et al. | Contradiction between in vitro and clinical outcome: intravenous followed by oral azithromycin therapy demonstrated clinical efficacy in macrolide-resistant pneumococcal pneumonia. | 2014 | J. Infect. Chemother. | pmid:24477328 |
| Zur G et al. | Azithromycin pharmacokinetics in the serum and its distribution to the skin in healthy dogs and dogs with pyoderma. | 2014 | Vet. J. | pmid:24472431 |
| Slater M et al. | The impact of azithromycin therapy on the airway microbiota in asthma. | 2014 | Thorax | pmid:24287164 |
| Farley R et al. | Antibiotics for bronchiolitis in children under two years of age. | 2014 | Cochrane Database Syst Rev | pmid:25300167 |
| Meltzer E et al. | A large outbreak of Salmonella Paratyphi A infection among israeli travelers to Nepal. | 2014 | Clin. Infect. Dis. | pmid:24198224 |
| Greene JB et al. | Oral azithromycin for the treatment of meibomitis. | 2014 | JAMA Ophthalmol | pmid:24201556 |
| Fan L et al. | Increased IL-8 production in human bronchial epithelial cells after exposure to azithromycin-pretreated Pseudomonas aeruginosa in vitro. | 2014 | FEMS Microbiol. Lett. | pmid:24716633 |
| Barbee LA | Preparing for an era of untreatable gonorrhea. | 2014 | Curr. Opin. Infect. Dis. | pmid:24685549 |
| Seidman JC et al. | Increased carriage of macrolide-resistant fecal E. coli following mass distribution of azithromycin for trachoma control. | 2014 | Int J Epidemiol | pmid:24659584 |
| Unemo M et al. | First three Neisseria gonorrhoeae isolates with high-level resistance to azithromycin in Sweden: a threat to currently available dual-antimicrobial regimens for treatment of gonorrhea? | 2014 | Antimicrob. Agents Chemother. | pmid:24189248 |
| Hassing RJ et al. | Salmonella subtypes with increased MICs for azithromycin in travelers returned to The Netherlands. | 2014 | Emerging Infect. Dis. | pmid:24655478 |
| Lösch B and Wank R | Life-threatening angioedema of the tongue: the detection of the RNA of B henselae in the saliva of a male patient and his dog as well as of the DNA of three Bartonella species in the blood of the patient. | 2014 | BMJ Case Rep | pmid:24654245 |
| Jensen JS et al. | In vitro activity of the new fluoroketolide solithromycin (CEM-101) against macrolide-resistant and -susceptible Mycoplasma genitalium strains. | 2014 | Antimicrob. Agents Chemother. | pmid:24637681 |
| Kakeya H et al. | Efficacy of combination therapy with oseltamivir phosphate and azithromycin for influenza: a multicenter, open-label, randomized study. | 2014 | PLoS ONE | pmid:24632748 |
| Liu F et al. | The efficacy of oral azithromycin in clearing ocular chlamydia: mathematical modeling from a community-randomized trachoma trial. | 2014 | Epidemics | pmid:24593917 |
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| Ferslew BC and Brouwer KL | Identification of hepatic phospholipidosis inducers in sandwich-cultured rat hepatocytes, a physiologically relevant model, reveals altered basolateral uptake and biliary excretion of anionic probe substrates. | 2014 | Toxicol. Sci. | pmid:24563379 |
| Gandhi SV et al. | Considerations for a Pediatric Biopharmaceutics Classification System (BCS): application to five drugs. | 2014 | AAPS PharmSciTech | pmid:24557773 |
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| Woodruff PG et al. | Tumour necrosis factor receptor-75 and risk of COPD exacerbation in the azithromycin trial. | 2014 | Eur. Respir. J. | pmid:24136332 |
| King JD et al. | Prevalence of trachoma at sub-district level in ethiopia: determining when to stop mass azithromycin distribution. | 2014 | PLoS Negl Trop Dis | pmid:24625539 |
| Xiao C et al. | Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births. | 2014 | J Perinat Med | pmid:24566358 |
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| Thakur SD et al. | Molecular epidemiology of Neisseria gonorrhoeae isolates from Saskatchewan, Canada: utility of NG-MAST in predicting antimicrobial susceptibility regionally. | 2014 | Sex Transm Infect | pmid:24503900 |
| Zhao Q et al. | Population pharmacokinetics of azithromycin and chloroquine in healthy adults and paediatric malaria subjects following oral administration of fixed-dose azithromycin and chloroquine combination tablets. | 2014 | Malar. J. | pmid:24472224 |
| Liu Y et al. | One man's poison is another man's meat: using azithromycin-induced phospholipidosis to promote ocular surface health. | 2014 | Toxicology | pmid:24613571 |
| Gaynor BD et al. | Impact of mass azithromycin distribution on malaria parasitemia during the low-transmission season in Niger: a cluster-randomized trial. | 2014 | Am. J. Trop. Med. Hyg. | pmid:24615132 |
| Khan MS et al. | Fatal heart rhythms associated with azithromycin. | 2014 | J Pak Med Assoc | pmid:24640827 |
| Abbass K et al. | Mycobacterium fortuitum breast abscess after nipple piercing. | 2014 | Can Fam Physician | pmid:24452562 |
| de Wall C et al. | Home spirometry as early detector of azithromycin refractory bronchiolitis obliterans syndrome in lung transplant recipients. | 2014 | Respir Med | pmid:24445061 |
| Wong E and Nguyen TV | A case-based approach to evaluating azithromycin use and cardiovascular risks. | 2014 | Consult Pharm | pmid:24413014 |
| Khosropour CM et al. | Comparing azithromycin and doxycycline for the treatment of rectal chlamydial infection: a retrospective cohort study. | 2014 | Sex Transm Dis | pmid:24413484 |
| Otake H et al. | Antimicrobial prophylaxis in tonsillectomy: the efficacy of preoperative single-dose oral administration of azithromycin in preventing surgical site infection. | 2014 | Acta Otolaryngol. | pmid:24215215 |
| Li X et al. | Physicochemical characterization and aerosol dispersion performance of organic solution advanced spray-dried microparticulate/nanoparticulate antibiotic dry powders of tobramycin and azithromycin for pulmonary inhalation aerosol delivery. | 2014 | Eur J Pharm Sci | pmid:24215736 |
| Vall-Mayans M et al. | Bubonic lymphogranuloma venereum with multidrug treatment failure. | 2014 | Int J STD AIDS | pmid:24216037 |
| Bin Abdulhak AA et al. | Azithromycin for elderly patients with pneumonia. | 2014 | JAMA | pmid:25268448 |
| Mortensen EM et al. | Azithromycin for elderly patients with pneumonia--reply. | 2014 | JAMA | pmid:25268450 |
| Jarand J and Field SK | Embrace simplicity when treating lady windermere. | 2014 | Chest | pmid:25091749 |
| Kubanova A et al. | Russian gonococcal antimicrobial susceptibility programme (RU-GASP)--resistance in Neisseria gonorrhoeae during 2009-2012 and NG-MAST genotypes in 2011 and 2012. | 2014 | BMC Infect. Dis. | pmid:24947981 |
| Liu Y and Ding J | The combined effect of azithromycin and insulin-like growth factor-1 on cultured human meibomian gland epithelial cells. | 2014 | Invest. Ophthalmol. Vis. Sci. | pmid:25125598 |
| Poachanukoon O et al. | Macrolides attenuate phorbol ester-induced tumor necrosis factor-α and mucin production from human airway epithelial cells. | 2014 | Pharmacology | pmid:24556631 |
| Kobayashi T et al. | Case report: failure under azithromycin treatment in a case of bacteremia due to Salmonella enterica Paratyphi A. | 2014 | BMC Infect. Dis. | pmid:25041573 |
| Balloy V et al. | Azithromycin analogue CSY0073 attenuates lung inflammation induced by LPS challenge. | 2014 | Br. J. Pharmacol. | pmid:24417187 |
| Gilliams EA et al. | Chloroquine-azithromycin combination antimalarial treatment decreases risk of respiratory- and gastrointestinal-tract infections in Malawian children. | 2014 | J. Infect. Dis. | pmid:24652498 |