Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Epiglottitis D004826 1 associated lipids
Furcation Defects D017823 1 associated lipids
Pseudolymphoma D019310 1 associated lipids
Tenosynovitis D013717 3 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Aphasia, Broca D001039 1 associated lipids
Heartburn D006356 2 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Luke DR and Foulds G Disposition of oral azithromycin in humans. 1997 Clin. Pharmacol. Ther. pmid:9209246
Nachbaur D et al. Cryptosporidiosis after CD34-selected autologous peripheral blood stem cell transplantation (PBSCT). Treatment with paromomycin, azithromycin and recombinant human interleukin-2. 1997 Bone Marrow Transplant. pmid:9208124
Ramos JT et al. Cryptosporidium in patients infected with human immunodeficiency virus: azithromycin revisited. 1997 J. Pediatr. pmid:9202631
Shaio MF and Yang KD Response of babesiosis to a combined regimen of quinine and azithromycin. 1997 Mar-Apr Trans. R. Soc. Trop. Med. Hyg. pmid:9196774
Waites K et al. In vitro activities of oral antimicrobial agents against penicillin-resistant Streptococcus pneumoniae: implications for outpatient treatment. 1997 South. Med. J. pmid:9191739
Na-Bangchang K et al. Activity of artemether-azithromycin versus artemether-doxycycline in the treatment of multiple drug resistant falciparum malaria. 1996 Southeast Asian J. Trop. Med. Public Health pmid:9185262
Paul TR et al. Delivery of azithromycin to Chlamydia trachomatis-infected polarized human endometrial epithelial cells by polymorphonuclear leucocytes. 1997 J. Antimicrob. Chemother. pmid:9184362
Hulten K et al. In-vitro activity of azithromycin in against intracellular Helicobacter pylori. 1996 J. Antimicrob. Chemother. pmid:9182105
Young H et al. Azithromycin and erythromycin resistant Neisseria gonorrhoeae following treatment with azithromycin. 1997 Int J STD AIDS pmid:9175650
Rodvold KA et al. Intrapulmonary steady-state concentrations of clarithromycin and azithromycin in healthy adult volunteers. 1997 Antimicrob. Agents Chemother. pmid:9174209
Kuzman I et al. Azithromycin in the treatment of pneumonias caused by Chlamydia spp: a retrospective study. 1996 Int J Clin Pharmacol Res pmid:9172008
Nilius AM et al. Variability in susceptibilities of Haemophilus influenzae to clarithromycin and azithromycin due to medium pH. 1997 J. Clin. Microbiol. pmid:9163435
Fernandez-Obregon AC Azithromycin for the treatment of acne. 1997 Int. J. Dermatol. pmid:9159021
Pacifico L and Chiesa C Efficacy of three-day azithromycin vs. ten-day penicillin V in the treatment of streptococcal pharyngitis. 1997 Pediatr. Infect. Dis. J. pmid:9154566
Yasin RM et al. Comparison of E-test with agar dilution methods in testing susceptibility of N. gonorrhoeae to azithromycin. 1997 Sex Transm Dis pmid:9153733
Trotta M et al. [Azithromycin combined with pyrimethamine in the treatment of neurotoxoplasmosis, in an AIDS patient]. 1997 Minerva Med. pmid:9148227
Worth S et al. Quality control guidelines for amoxicillin, amoxicillin-clavulanate, azithromycin, piperacillin-tazobactam, roxithromycin, ticarcillin, ticarcillin-clavulanate, trovafloxacin (CP 99,219), U-100592, and U-100766 for various National Committee for Clinical Laboratory Standards susceptibility testing methods. Results from multicenter trials. 1996 Diagn. Microbiol. Infect. Dis. pmid:9147914
Littlewood-Evans AJ et al. Effect of combination therapy of rifampicin and azithromycin on TNF levels during a rat model of chronic osteomyelitis. 1997 J. Antimicrob. Chemother. pmid:9145822
Brown BA et al. Relationship of adverse events to serum drug levels in patients receiving high-dose azithromycin for mycobacterial lung disease. 1997 Clin. Infect. Dis. pmid:9142801
Khan WA et al. Treatment of shigellosis: V. Comparison of azithromycin and ciprofloxacin. A double-blind, randomized, controlled trial. 1997 Ann. Intern. Med. pmid:9139555