Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Epiglottitis D004826 1 associated lipids
Furcation Defects D017823 1 associated lipids
Pseudolymphoma D019310 1 associated lipids
Tenosynovitis D013717 3 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Aphasia, Broca D001039 1 associated lipids
Heartburn D006356 2 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Levert H et al. Azithromycin impact on neutrophil oxidative metabolism depends on exposure time. 1998 Inflammation pmid:9561928
Hoppe JE and Bryskier A In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). 1998 Antimicrob. Agents Chemother. pmid:9559823
Dietz A et al. [Macrolide antibiotic-induced vasculitis (Churg-Strauss syndrome)]. 1998 Laryngorhinootologie pmid:9555706
Mortensen JE et al. In vitro activity of oral antimicrobial agents against clinical isolates of Pasteurella multocida. 1998 Diagn. Microbiol. Infect. Dis. pmid:9554176
Hoepelman IM et al. A short (3-day) course of azithromycin tablets versus a 10-day course of amoxycillin-clavulanic acid (co-amoxiclav) in the treatment of adults with lower respiratory tract infections and effects on long-term outcome. 1997 Int. J. Antimicrob. Agents pmid:9552709
Chakrabarti MK et al. Evaluation of different antibiotics in inhibiting colonization of Vibrio cholerae O1 and O139 in the rabbit intestine. 1998 Mar-Apr Chemotherapy pmid:9551241
Walsh T et al. Randomised controlled trial of prophylactic antibiotics before insertion of intrauterine devices. IUD Study Group. 1998 Lancet pmid:9546505
Mizutani S [Nontuberculous mycobacteriosis; the present status and in the future. Infection with human immunodeficiency virus (HIV) and nontuberculous mycobacteriosis]. 1998 Kekkaku pmid:9545702
Karcioglu ZA et al. Pharmacokinetics of azithromycin in trachoma patients: serum and tear levels. 1998 Ophthalmology pmid:9544640
Jucglà A et al. The use of azithromycin for cyclosporin-induced gingival overgrowth. 1998 Br. J. Dermatol. pmid:9536254
Kemper CA et al. Immunomodulatory treatment of Mycobacterium avium complex bacteremia in patients with AIDS by use of recombinant granulocyte-macrophage colony-stimulating factor. 1998 J. Infect. Dis. pmid:9534963
Rajyaguru JM and Muszynski MJ Sensitization of Burkholderia cepacia to antibiotics by cationic drugs. 1998 J. Antimicrob. Chemother. pmid:9533472
Dzelalija B et al. [Azithromycin in the prevention of Mediterranean spotted fever]. 1997 Lijec Vjesn pmid:9531759
Socan M Treatment of atypical pneumonia with azithromycin: comparison of a 5-day and a 3-day course. 1998 J Chemother pmid:9531077
Leri O et al. [Effects of the triple therapy in the eradication of Helicobacter pylori: comparison of 3 different antibiotics]. 1997 Clin Ter pmid:9528197
Kashuba AD and Amsden GW Bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. 1998 Antimicrob. Agents Chemother. pmid:9527816
Fuentes F et al. Postanitbiotic and sub-MIC effects of azithromycin and isepamicin against Staphylococcus aureus and Escherichia coli. 1998 Antimicrob. Agents Chemother. pmid:9527796
den Hollander JG et al. Comparison of pharmacodynamics of azithromycin and erythromycin in vitro and in vivo. 1998 Antimicrob. Agents Chemother. pmid:9527789
Oldfield EC et al. Once weekly azithromycin therapy for prevention of Mycobacterium avium complex infection in patients with AIDS: a randomized, double-blind, placebo-controlled multicenter trial. 1998 Clin. Infect. Dis. pmid:9524832
Bowden FJ and Savage J Donovanosis: treatment with azithromycin. 1998 Int J STD AIDS pmid:9518024