| MeSH term | MeSH ID | Detail |
|---|---|---|
| Fatty Liver | D005234 | 48 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Weight Loss | D015431 | 56 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
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| Gawin A et al. | Mildly pruritic palmar rash. | 2016 | J Fam Pract | pmid:28087868 |
| Weintraub A et al. | In-vitro activity of solithromycin against anaerobic bacteria from the normal intestinal microbiota. | 2016 | Anaerobe | pmid:27725229 |
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| Petrelli F et al. | Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice. | 2016 | Eur. J. Pharmacol. | pmid:27663279 |
| Gerhardt P et al. | [Male urethritis]. | 2016 | Ann Dermatol Venereol | pmid:27776813 |
| Samson C et al. | Long-term effects of azithromycin in patients with cystic fibrosis. | 2016 | Respir Med | pmid:27492507 |
| Akram FE et al. | A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). | 2016 | Ann. Clin. Microbiol. Antimicrob. | pmid:27530257 |
| Caumes E et al. | [Donovanosis (granuloma inguinale)]. | 2016 | Ann Dermatol Venereol | pmid:27773509 |
| O'Farrell N | Control of gonorrhoea and chlamydia in the UK. | 2016 | Lancet | pmid:27477165 |
| Zhu XH et al. | Viral and Bacterial Etiology of Acute Diarrhea among Children under 5 Years of Age in Wuhan, China. | 2016 | Chin. Med. J. | pmid:27503019 |
| Zhao M et al. | Comparison of minocycline and azithromycin for the treatment of mild scrub typhus in northern China. | 2016 | Int. J. Antimicrob. Agents | pmid:27449540 |
| Dukers-Muijrers NH et al. | Design of the FemCure study: prospective multicentre study on the transmission of genital and extra-genital Chlamydia trachomatis infections in women receiving routine care. | 2016 | BMC Infect. Dis. | pmid:27502928 |
| Huang SW et al. | Azithromycin impairs TLR7 signaling in dendritic cells and improves the severity of imiquimod-induced psoriasis-like skin inflammation in mice. | 2016 | J. Dermatol. Sci. | pmid:27449383 |
| Yoshioka D et al. | Efficacy of β-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal Pneumonia. | 2016 | Antimicrob. Agents Chemother. | pmid:27480866 |
| Jacobsson S et al. | WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014. | 2016 | J. Antimicrob. Chemother. | pmid:27432597 |
| Jeong BH et al. | Peak Plasma Concentration of Azithromycin and Treatment Responses in Mycobacterium avium Complex Lung Disease. | 2016 | Antimicrob. Agents Chemother. | pmid:27480854 |
| de Zwart L et al. | Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling. | 2016 | Clin. Pharmacol. Ther. | pmid:27367453 |
| Abeles SR et al. | Microbial diversity in individuals and their household contacts following typical antibiotic courses. | 2016 | Microbiome | pmid:27473422 |
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| Brown J et al. | Shigellosis: high rates of antibiotic resistance necessitate new treatment recommendations. | 2016 | Med. J. Aust. | pmid:27078594 |
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| Rajabi O et al. | Topical liposomal azithromycin in the treatment of acute cutaneous leishmaniasis. | 2016 | Dermatol Ther | pmid:27073044 |
| Geisler WM et al. | Azithromycin versus Doxycycline for Chlamydia. | 2016 | N. Engl. J. Med. | pmid:27144856 |
| Dunn AL et al. | Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl. | 2016 | Lab Med | pmid:26984830 |
| Yelenich-Huss MJ et al. | Ozena in Immigrants of Differing Backgrounds. | 2016 | Am. J. Trop. Med. Hyg. | pmid:27114295 |
| Saini H et al. | Antimicrobial and antifouling efficacy of urinary catheters impregnated with a combination of macrolide and fluoroquinolone antibiotics against Pseudomonas aeruginosa. | 2016 | Biofouling | pmid:26982572 |
| Vermeersch K et al. | The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial. | 2016 | Int J Chron Obstruct Pulmon Dis | pmid:27099485 |
| Levy V et al. | A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea. | 2016 | Sex Transm Dis | pmid:26967304 |
| Guo Y et al. | Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. | 2016 | Viruses | pmid:27089359 |
| Gülses A and Ayna M | Re: Comparison of Azithromycin and Amoxicillin Before Dental Implant Placement: An Exploratory Study of Bioavailability and Resolution of Postoperative Inflammation. | 2016 | J. Periodontol. | pmid:26962889 |
| Hu J et al. | Streptococcus pneumoniae and Haemophilus influenzae type b carriage in Chinese children aged 12-18 months in Shanghai, China: a cross-sectional study. | 2016 | BMC Infect. Dis. | pmid:27080523 |
| McClure KS and Cameron ST | An audit of expedited treatment for uncomplicated Chlamydia trachomatis index cases at the community pharmacy. | 2016 | Int J STD AIDS | pmid:26945591 |
| Afshar M et al. | Azithromycin use and outcomes in severe sepsis patients with and without pneumonia. | 2016 | J Crit Care | pmid:26803186 |
| Lee H et al. | New treatment options for infections caused by increasingly antimicrobial-resistant Neisseria gonorrhoeae. | 2016 | Expert Rev Anti Infect Ther | pmid:26690658 |
| Nakajima T et al. | Microbiological and Clinical Effects of Sitafloxacin and Azithromycin in Periodontitis Patients Receiving Supportive Periodontal Therapy. | 2016 | Antimicrob. Agents Chemother. | pmid:26729495 |
| Jentsch HF et al. | Nonsurgical therapy of chronic periodontitis with adjunctive systemic azithromycin or amoxicillin/metronidazole. | 2016 | Clin Oral Investig | pmid:26685849 |
| Slade J et al. | Chlamydial Pre-Infection Protects from Subsequent Herpes Simplex Virus-2 Challenge in a Murine Vaginal Super-Infection Model. | 2016 | PLoS ONE | pmid:26726882 |
| Lococo F et al. | Hemoptysis and Progressive Dyspnea in a 67-Year-Old Woman with History of Renal Transplantation. | 2016 | Am. J. Respir. Crit. Care Med. | pmid:26681504 |
| Mukai S et al. | Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. | 2016 | Int. J. Oncol. | pmid:26718641 |
| Miyagawa T et al. | Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-α. | 2016 | Arch. Oral Biol. | pmid:26655749 |
| Smith DJ et al. | Pseudomonas aeruginosa antibiotic resistance in Australian cystic fibrosis centres. | 2016 | Respirology | pmid:26711802 |
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| Lee SJ et al. | Maternal azithromycin administration eradicates intra-amniotic Ureaplasma infection: The first human case report. | 2016 | J Obstet Gynaecol | pmid:26634623 |
| Martin I et al. | Decline in Decreased Cephalosporin Susceptibility and Increase in Azithromycin Resistance in Neisseria gonorrhoeae, Canada. | 2016 | Emerging Infect. Dis. | pmid:26689114 |
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| Unger HW et al. | Azithromycin-containing intermittent preventive treatment in pregnancy affects gestational weight gain, an important predictor of birthweight in Papua New Guinea - an exploratory analysis. | 2016 | Matern Child Nutr | pmid:26373537 |
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| Chang Y et al. | Factors Influencing the HPLC Determination for Related Substances of Azithromycin. | 2016 | J Chromatogr Sci | pmid:26324196 |
| Caspi M et al. | A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. | 2016 | J. Mol. Med. | pmid:26620677 |
| Derad I et al. | Hypertension and mild chronic kidney disease persist following severe haemolytic uraemic syndrome caused by Shiga toxin-producing Escherichia coli O104:H4 in adults. | 2016 | Nephrol. Dial. Transplant. | pmid:26180049 |
| Steeples LR et al. | Real-time PCR using the 529 bp repeat element for the diagnosis of atypical ocular toxoplasmosis. | 2016 | Br J Ophthalmol | pmid:26174811 |
| Arora N et al. | Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster. | 2016 | Nat Microbiol | pmid:27918528 |
| Retallack H et al. | Zika virus cell tropism in the developing human brain and inhibition by azithromycin. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:27911847 |
| Brittain C et al. | Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial. | 2016 | Trials | pmid:27881151 |
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| Oliveira IS et al. | Evaluation of the improvement of quality of life with Azithromycin in the treatment of eosinophilic nasal polyposis. | 2016 Mar-Apr | Braz J Otorhinolaryngol | pmid:26601998 |
| Akoglu G et al. | Erlotinib-induced purpuric papulopustular eruption treated with pulsed azithromycin. | 2016 May-Jun | Indian J Pharmacol | pmid:27298507 |
| Diniz LM et al. | Bacillary angiomatosis with bone invasion. | 2016 Nov-Dec | An Bras Dermatol | pmid:28099606 |
| Jordan SJ et al. | Lower Levels of Cervicovaginal Tryptophan Are Associated With Natural Clearance of Chlamydia in Women. | 2017 | J. Infect. Dis. | pmid:28520912 |
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| Lee SC et al. | Comparative effectiveness of azithromycin for treating scrub typhus: A PRISMA-compliant systematic review and meta-analysis. | 2017 | Medicine (Baltimore) | pmid:28885357 |
| Mandhane PJ et al. | Treatment of preschool children presenting to the emergency department with wheeze with azithromycin: A placebo-controlled randomized trial. | 2017 | PLoS ONE | pmid:28771627 |
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| Sharpton R et al. | Do cystic fibrosis patients on azithromycin need electrocardiogram monitoring? | 2017 | Pulm Pharmacol Ther | pmid:28219728 |
| Braam JF et al. | High prevalence of the A2058T macrolide resistance-associated mutation in Mycoplasma genitalium strains from the Netherlands. | 2017 | J. Antimicrob. Chemother. | pmid:28158595 |
| Asano N et al. | Limited Azithromycin Localization to Rabbit Meibomian Glands Revealed by LC-MS-Based Bioanalysis and DESI Imaging. | 2017 | Biol. Pharm. Bull. | pmid:28867744 |
| Seyama S et al. | Amino Acid Substitution in the Major Multidrug Efflux Transporter Protein AcrB Contributes to Low Susceptibility to Azithromycin in Haemophilus influenzae. | 2017 | Antimicrob. Agents Chemother. | pmid:28848006 |
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| Saini H et al. | Azithromycin-Ciprofloxacin-Impregnated Urinary Catheters Avert Bacterial Colonization, Biofilm Formation, and Inflammation in a Murine Model of Foreign-Body-Associated Urinary Tract Infections Caused by Pseudomonas aeruginosa. | 2017 | Antimicrob. Agents Chemother. | pmid:28031194 |
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| Lee N et al. | Anti-inflammatory effects of adjunctive macrolide treatment in adults hospitalized with influenza: A randomized controlled trial. | 2017 | Antiviral Res. | pmid:28535933 |
| Allen GP and Harris KA | Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin. | 2017 | Antimicrob. Agents Chemother. | pmid:28483960 |
| Waetzig V et al. | Neurodegenerative effects of azithromycin in differentiated PC12 cells. | 2017 | Eur. J. Pharmacol. | pmid:28479141 |
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| Bergeron A et al. | Azithromycin and Survival After Hematopoietic Stem Cell Transplant-Reply. | 2017 | JAMA | pmid:29279924 |